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EP About this file: EP2265620

EP2265620 - SPIRO DERIVATIVES OF PARTHENIN AS NOVEL ANTICANCER AGENTS [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 24.04.2015 Database last updated on 02.08.2024
Most recent event Tooltip	22.06.2018	Lapse of the patent in a contracting state New state(s): MK	published on 25.07.2018 [2018/30]
Applicant(s)	For all designated states Council Of Scientific & Industrial Research ̈An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) ̈ Anusandhan Bhawan 2 Rafi Marg. New Delhi 110 001 / IN
	[2014/22]
Former [2010/52]	For all designated states Council Of Scientific & Industrial Research ̈An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) ̈ Anusandhan Bhawan 2 Rafi Marg. New Delhi 110 001 / IN
	For all designated states Verma, Monika Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
Inventor(s)	01 / HALMUTHUR, Mahabalarao, Sampath, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	02 / SAXENA, Ajit, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	03 / TANEJA Subhash, Chandra Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	04 / SINGH, Shashank, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	05 / SETHI, Vijay, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	06 / QAZI, Naveed, Ahmed Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	07 / SAWANT, Sanghapal, Damodhar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	08 / DOMA, Mahendhar, Reddy Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	09 / BANDAY, Abid, Hussain Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	10 / QAZI, Ghularn, Nabi Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	11 / VERMA, Monika Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	[2014/20]
Former [2010/52]	01 / HALMUTHUR, Mahabalarao, Sampath, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	02 / SAXENA, Ajit, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	03 / TANEJA1 Subhash, Chandra Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	04 / SINGH, Shashank, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	05 / SETHI, Vijay, Kumar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	06 / QAZI, Naveed, Ahmed Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	07 / SAWANT, Sanghapal, Damodhar Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	08 / DOMA, Mahendhar, Reddy Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	09 / BANDAY, Abid, Hussain Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	10 / QAZI, Ghularn, Nabi Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
	11 / VERMA, Monika Indian Institute of Integrative Medicine Canal Road Jammu Tawi 180 001 / IN
Representative(s)	Towler, Philip Dean Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD / GB
	[N/P]
Former [2014/25]	Towler, Philip Dean Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD / GB
Former [2010/52]	Towler, Philip Dean Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD / GB
Application number, filing date	09717600.2	05.03.2009
	[2010/52]
	WO2009IN00153
Priority number, date	IN2008DEL0527	05.03.2008 Original published format: IN DE05272008
	[2010/52]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2009110007
	Date:	11.09.2009
	Language:	EN
	[2009/37]
	Type:	A1 Application with search report
	No.:	EP2265620
	Date:	29.12.2010
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 11.09.2009 takes the place of the publication of the European patent application.
	[2010/52]
	Type:	B1 Patent specification
	No.:	EP2265620
	Date:	18.06.2014
	Language:	EN
	[2014/25]
Search report(s)	International search report - published on:	EP	11.09.2009
Classification	IPC:	C07D498/10, C07D491/107, A61K31/424, A61K31/4192, A61K31/396, A61P35/00	[2010/52]
	CPC:	C07D491/107 (EP,US); A61P35/00 (EP); A61P35/02 (EP); C07D498/10 (EP,US)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2010/52]
Title	German:	SPIRO-DERIVATE VON PARTHENIN ALS NEUE ANTIKREBSMITTEL	[2010/52]
	English:	SPIRO DERIVATIVES OF PARTHENIN AS NOVEL ANTICANCER AGENTS	[2010/52]
	French:	DÉRIVÉS SPIRO DE PARTHÉNINE SERVANT DE NOUVEAUX AGENTS ANTICANCÉREUX	[2010/52]
Entry into regional phase	21.09.2010	National basic fee paid
	21.09.2010	Designation fee(s) paid
	21.09.2010	Examination fee paid
Examination procedure	05.01.2010	Request for preliminary examination filed International Preliminary Examining Authority: EP
	21.09.2010	Amendment by applicant (claims and/or description)
	21.09.2010	Examination requested [2010/52]
	21.05.2012	Despatch of a communication from the examining division (Time limit: M04)
	01.10.2012	Reply to a communication from the examining division
	26.11.2012	Despatch of a communication from the examining division (Time limit: M04)
	08.04.2013	Reply to a communication from the examining division
	28.11.2013	Communication of intention to grant the patent
	28.03.2014	Fee for grant paid
	28.03.2014	Fee for publishing/printing paid
	07.04.2014	Receipt of the translation of the claim(s)
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 21.05.2012
Opposition(s)	19.03.2015	No opposition filed within time limit [2015/22]
Fees paid	Renewal fee
	28.03.2011	Renewal fee patent year 03
	26.03.2012	Renewal fee patent year 04
	26.03.2013	Renewal fee patent year 05
	18.03.2014	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	05.03.2009
	AT	18.06.2014
	BE	18.06.2014
	BG	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	GR	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	MC	18.06.2014
	MK	18.06.2014
	MT	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	TR	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
	IE	05.03.2015
	LU	05.03.2015
	[2018/30]
Former [2017/39]	HU	05.03.2009
	AT	18.06.2014
	BE	18.06.2014
	BG	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	GR	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	MC	18.06.2014
	MT	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	TR	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
	IE	05.03.2015
	LU	05.03.2015
Former [2017/03]	AT	18.06.2014
	BE	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	MC	18.06.2014
	MT	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
	IE	05.03.2015
	LU	05.03.2015
Former [2016/07]	AT	18.06.2014
	BE	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	MC	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
	IE	05.03.2015
	LU	05.03.2015
Former [2015/47]	AT	18.06.2014
	BE	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	MC	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
	LU	05.03.2015
Former [2015/46]	AT	18.06.2014
	BE	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	MC	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
Former [2015/36]	AT	18.06.2014
	BE	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SI	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
Former [2015/30]	AT	18.06.2014
	BE	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
Former [2015/22]	AT	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	DK	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	IT	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
Former [2015/12]	AT	18.06.2014
	CY	18.06.2014
	CZ	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	NL	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	IS	18.10.2014
	PT	20.10.2014
Former [2015/11]	CY	18.06.2014
	CZ	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	PL	18.06.2014
	RO	18.06.2014
	SE	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
	PT	20.10.2014
Former [2015/10]	CY	18.06.2014
	CZ	18.06.2014
	EE	18.06.2014
	ES	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	SE	18.06.2014
	SK	18.06.2014
	NO	18.09.2014
Former [2014/50]	CY	18.06.2014
	FI	18.06.2014
	HR	18.06.2014
	LT	18.06.2014
	LV	18.06.2014
	SE	18.06.2014
	NO	18.09.2014
Former [2014/49]	CY	18.06.2014
	FI	18.06.2014
	LT	18.06.2014
	NO	18.09.2014
Former [2014/48]	CY	18.06.2014
	LT	18.06.2014
Former [2014/47]	CY	18.06.2014
Cited in	International search	[X] - DAS ET AL, "Synthetic studies on natural products. Part 20. Synthesis of novel spiro-2-isoxazolines derived from parthenin", INDIAN JOURNAL OF CHEMISTRY, (2005), vol. 44B, no. 10, pages 2149 - 2151, XP002380557 [X] 1,2,6,7 * Scheme I compounds of formulae 3 and 4 Experimental Section; page 2149, column 1, paragraph 2 - column 2, paragraph 1 * * page 2159, column 1, paragraph 1 *
		[X] - HOOPER M ET AL, "Antimalarial activity of parthenin and its derivatives", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 25, no. 9, ISSN 0223-5234, (19901101), pages 717 - 723, (19901101), XP023870757 [X] 1 * abstract * DOI: http://dx.doi.org/10.1016/0223-5234(90)90190-E
		[X] - DATTA S ET AL, "PESTICIDAL PROPERTIES OF PARTHENIN (FROM PARTHENIUM HYSTEROPHORUS) AND RELATED COMPOUNDS", PEST MANAGEMENT SCIENCE, WILEY & SONS, BOGNOR REGIS, GB, (20010101), vol. 57, no. 1, ISSN 1526-498X, pages 95 - 101, XP001011687 [X] 1 * abstract * DOI: http://dx.doi.org/10.1002/1526-4998(200101)57:1<95::AID-PS248>3.0.CO;2-J
	by applicant	- HERZ, W.; WATANABE, H.; MIYAZAKI, M.; KISHIDA. Y, J AM. CHEM. SOC, (1962), vol. 84, page 2601
		- SCHMIDT, T. J., "Toxic Activities of Sesquiterpene Lactones - structural and Biochemical Aspects", CURRENT ORG. CHEM., (1999), vol. 3, pages 577 - 608
		- HUISGEN, R., ANGEW. CHEM INT. ED. ENGL., (1963), vol. 2, page 565
		- PADWA, A, ANGEW. CHEM., (1976), vol. 88, page 131
		- HAMER, J.; MACALUSO, A, CHEM. REV., (1964), vol. 64, page 473
		- KUMAR, H. M. S.; ANJANEYULU, S.; YADAV, J. S, SYNTHETIC COMM., (1999), vol. 29, page 877
		- KUMAR, H. M. S.; ANJANEYULU, S.; REDDY, B. V. S.; YADAV, J. S., SYNLETT, (1999), vol. 5, page 551

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

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