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Extract from the Register of European Patents

EP About this file: EP2273985

EP2273985 - CAPSULE FOR THE PREVENTION OF CARDIOVASCULAR DISEASES [Right-click to bookmark this link]
StatusOpposition rejected
Status updated on  03.08.2018
Database last updated on 13.07.2024
FormerThe patent has been granted
Status updated on  19.04.2018
Most recent event   Tooltip03.08.2018Opposition rejectedpublished on 05.09.2018  [2018/36]
Applicant(s)For all designated states
Ferrer Internacional, S.A.
Gran Via Carlos III, 94
08028 Barcelona / ES
For all designated states
CNIC Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
C/Melchor Fernández Almagro, 3
28029 Madrid / ES
[2015/38]
Former [2013/16]For all designated states
Ferrer Internacional, S.A.
Gran Via Carlos III, 94
08028 Barcelona / ES
For all designated states
CNIC, Fundacion Centro Nacional de Investigaciones Cardiovasculares Carlos III
Melchor Fernandez Almagro, 3
28029 Madrid / ES
Former [2011/03]For all designated states
Ferrer Internacional, S.A.
Gran Via Carles III 94
08028 Barcelona / ES
For all designated states
CNIC, Fundacion Centro Nacional de Investigaciones Cardiovasculares Carlos III
Melchor Fernandez Almagro, 3
28029 Madrid / ES
Inventor(s)01 / GUERRERO, Marta
Travessera de Dalt 73
E-08024 Barelona / ES
02 / ORRIOLS, Anna
Tortonyes 25-C 2°2a
E-08242 Manresa / ES
03 / MARTÍN, Pablo
Joan XXIII 44 Bjos. 1a
E-08173 Barcelona / ES
04 / RAGA, Manuel
Sors 17-21
E-08024 Barcelona / ES
 [2011/03]
Representative(s)Reitstötter Kinzebach
Patentanwälte
Sternwartstraße 4
81679 München / DE
[N/P]
Former [2016/07]Reitstötter Kinzebach
Patentanwälte
Sternwartstrasse 4
81679 München / DE
Former [2011/03]Reitstötter - Kinzebach
Patentanwälte Sternwartstrasse 4
81679 München / DE
Application number, filing date09724677.125.03.2009
[2011/03]
WO2009EP53545
Priority number, dateEP2008015361528.03.2008         Original published format: EP 08153615
[2011/03]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2009118359
Date:01.10.2009
Language:EN
[2009/40]
Type: A2 Application without search report 
No.:EP2273985
Date:19.01.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 01.10.2009 takes the place of the publication of the European patent application.
[2011/03]
Type: B1 Patent specification 
No.:EP2273985
Date:17.02.2016
Language:EN
[2016/07]
Search report(s)International search report - published on:EP06.05.2010
ClassificationIPC:A61K31/60, A61K31/22, A61K31/366, A61K31/401, A61K31/403, A61K31/405, A61K31/616, A61K9/48, A61K9/20, A61K9/28, A61P9/00
[2015/38]
CPC:
A61K9/4816 (EP,US); A61K31/366 (EP,US); A61K31/403 (EP,US);
A61K31/60 (EP,US); A61K31/616 (EP,US); A61K9/2009 (EP,US);
A61K9/2018 (EP,US); A61K9/2054 (EP,US); A61K9/2059 (EP,US);
A61K9/284 (EP,US); A61K9/2866 (EP,US); A61P13/12 (EP);
A61P29/00 (EP); A61P3/06 (EP); A61P3/10 (EP);
A61P43/00 (EP); A61P9/00 (EP); A61P9/04 (EP);
A61P9/10 (EP); A61P9/12 (EP) (-)
C-Set:
A61K31/366, A61K2300/00 (EP,US);
A61K31/403, A61K2300/00 (US,EP);
A61K31/60, A61K2300/00 (US,EP);
A61K31/616, A61K2300/00 (US,EP)
Former IPC [2011/03]A61K9/48, A61P9/00, A61K31/60, A61K31/22, A61K31/366, A61K31/401, A61K31/403, A61K31/405
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/07]
Former [2011/03]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:KAPSEL ZUR PRÄVENTION VON KARDIOVASKULÄREN ERKRANKUNGEN[2015/38]
English:CAPSULE FOR THE PREVENTION OF CARDIOVASCULAR DISEASES[2011/03]
French:CAPSULE POUR LA PRÉVENTION DES MALADIES CARDIOVASCULAIRES[2015/38]
Former [2011/03]KAPSEL ZUR PRÄVENTION VON HERZ-KREISLAUF-ERKRANKUNGEN
Former [2011/03]Capsule pour la prévention des maladies cardiovasculaires
Entry into regional phase26.10.2010National basic fee paid 
26.10.2010Designation fee(s) paid 
26.10.2010Examination fee paid 
Examination procedure02.06.2010Request for preliminary examination filed
International Preliminary Examining Authority: EP
26.10.2010Examination requested  [2011/03]
30.12.2010Amendment by applicant (claims and/or description)
22.03.2012Despatch of a communication from the examining division (Time limit: M07)
14.12.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
15.02.2013Reply to a communication from the examining division
20.08.2015Communication of intention to grant the patent
11.12.2015Fee for grant paid
11.12.2015Fee for publishing/printing paid
11.12.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.03.2012
Opposition(s)Opponent(s)01  17.11.2016  23.11.2016  ADMISSIBLE
ELLIS IP LTD
53/4 George Street
Edinburgh EH2 2HT / GB
Opponent's representative
Ellis, Michael James
Ellis IP Ltd
53/4 George Street
Edinburgh EH2 2HT / GB
 [2017/06]
Former [2016/52]
Opponent(s)01  17.11.2016  23.11.2016  ADMISSIBLE
ELLIS IP LTD
Newbyth House East Linton East Lothian
EH40 3DU / GB
Opponent's representative
Ellis, Michael James
Ellis IP Ltd
Newbyth House
East Linton
East Lothian EH40 3DU / GB
04.01.2017Invitation to proprietor to file observations on the notice of opposition
15.05.2017Reply of patent proprietor to notice(s) of opposition
27.03.2018Legal effect of rejection of opposition [2018/36]
27.03.2018Date of oral proceedings
20.04.2018Despatch of minutes of oral proceedings
20.04.2018Date of despatch of rejection of opposition
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
15.02.2013Request for further processing filed
15.02.2013Full payment received (date of receipt of payment)
Request granted
04.03.2013Decision despatched
Fees paidRenewal fee
31.03.2011Renewal fee patent year 03
30.03.2012Renewal fee patent year 04
27.03.2013Renewal fee patent year 05
27.03.2014Renewal fee patent year 06
27.03.2015Renewal fee patent year 07
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Lapses during opposition  TooltipEE17.02.2016
IS17.02.2016
LT17.02.2016
LV17.02.2016
MC17.02.2016
MK17.02.2016
LU25.03.2016
[2018/30]
Former [2016/49]EE17.02.2016
LT17.02.2016
LV17.02.2016
Former [2016/39]LT17.02.2016
LV17.02.2016
Former [2016/36]LT17.02.2016
Cited inInternational search[A]WO0158429  (BPSI HOLDINGS INC [US], et al) [A] 1-8 * page 10, lines 7-12 *;
 [XD]WO03020243  (LONGWOOD PHARMACEUTICAL RES IN [US]) [XD] 1-8 * examples 5,6; claims 1-31 *;
 [XD]WO2004080488  (BAYER HEALTHCARE AG [DE], et al) [XD] 1-8 * examples 18,19; claims 1-19 *;
 [XD]WO2005011586  (REDDYS LAB INC DR [US], et al) [XD] 1-8 * example 5; claims 1-24 *;
 [A]EP1657265  (SHIONOGI & CO [JP], et al) [A] 1-8* figure 5; example 3 *;
 [A]US2007009591  (TRIVEDI JAY S [US], et al) [A] 1-8 * the whole document *;
 [XD]US2007116756  (KOMIREDDI PRAKASH R [IN], et al) [XD] 1-8 * examples 1,7; claims 1-17 *;
 [A]US2007166375  (PATEL SHASHANK BABABHAI [IN], et al) [A] 1-8 * example 4 *;
 [AP]WO2009022821  (HANALL PHARMACEUTICAL CO LTD [KR], et al) [AP] 1-8 * example 33; tables 8-9 *
Examination   - LAW M R ET AL, "Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials", BMJ. BRITISH MEDICAL JOURNAL, LONDON, GB, vol. 326, no. 7404, doi:10.1136/BMJ.326.7404.1427, ISSN 0959-8146, (20030628), pages 1427 - 1431, (20030625), XP008145737

DOI:   http://dx.doi.org/10.1136/bmj.326.7404.1427
    - SCHIEFFER B ET AL, "Role of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors, angiotensin-converting enzyme inhibitors, cyclooxygenase-2 inhibitors, and aspirin in anti-inflammatory and immunomodulatory treatment of cardiovascular diseases", AMERICAN JOURNAL OF CARDIOLOGY, CAHNERS PUBLISHING CO., NEWTON, MA, US, (20030619), vol. 91, no. 12A, ISSN 0002-9149, pages 12H - 18H, XP001573308

DOI:   http://dx.doi.org/10.1016/S0002-9149(03)00429-6
    - HOLZGRABE U, "How stable are drugs Wie stabil sind Anneimittel", PHARMAZEUTISCHE ZEITUNG, GOVI VERLAG, ESCHBORN, DE, (20040101), vol. 149, no. 26, ISSN 0031-7136, pages 32 - 35, XP008145787
    - FEHER GERGELY ET AL, "Aspirin Resistance: Possible Roles of Cardiovascular Risk Factors, Previous Disease History, Concomitant Medications and Haemorrheological Variables", DRUGS & AGING, ADIS INTERNATIONAL LTD, AUCKLAND,NEW ZEALAND, (20060101), vol. 23, no. 7, ISSN 1170-229X, pages 559 - 567, XP008145786
OppositionUS5442008
 WO03020243
 WO2009022821
    - FEGELY K et al., "Correlation of free salicylic acid content to the water vapor transmission properties of aqueous film coating systems", Poster presentation, American Association of Pharmaceutical Scientists Annual Meeting, Salt Lake City, UT, USA, (20031001), pages 1 - 6, URL: https://www.colorcon.com/literature/marketing/fc/Opadry%20amb/ads_opadry_amb_corr_free_salic_acid.pdf, XP055323873
    - Anonymous, "Opadry® AMB, Colorcon", Colorcon, (20030321), page 1, URL: http://www.fdec.com.tw/static/media/uploads/documents/opadry_amb-1.pdf, XP055325666
    - Sven Stegemann, "Hard gelatin capsules today - and tomorrow", Capsugel Library, (20020000), pages 2 - 23, URL: http://www.capsugel.com/media/library/hard-gelatin-capsules-today-and-tomorrow.pdf, XP008128828
    - DAVID B. TROY et al., "Chapter 45: Oral solid dosage forms", Remington The Science and Practice of Pharmacy 21st edition, page 919, ISBN 0-7817-4673-6, XP055323937
    - Clark A Kelly, "Determination of the decomposition of aspirin", J Pharm Sci., (19700800), vol. 59, no. 8, pages 1053 - 1079, XP008182502

DOI:   http://dx.doi.org/10.1002/jps.2600590802
    - Anonymous, "ICH HARMONISED TRIPARTITE GUIDELINE, 2003 STABILITY TESTING OF NEW DRUG SUBSTANCES AND PRODUCTS Q1A(R2", INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE,, (20030206), pages 1 - 24, URL: http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Quality/Q1A_R2/Step4/Q1A_R2__Guideline.pdf, XP055325580
    - T L Rogers, "Hypromellose", T L Rogers, RAYMOND C. ROWE, Handbook of Pharmaceutical Excipients, Pharmaceutical Press, (20090220), pages 326 - 329, ISBN 9780853697923, XP055325597
    - N J Wald, M R Law, "A strategy to reduce cardiovascular disease by more than 80%", BMJ. BRITISH MEDICAL JOURNAL, (20030628), vol. 326, pages 1 - 6, XP008042512
    - Anonymous, "Simvacor. Summary of product characteristics.", (20050401), pages 1 - 12, URL: http://www.actavis.com.mt/NR/rdonlyres/3231D4F1-BEAF-434A-B273-AF6B7F40554F/0/Si.., XP055325622
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.