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Extract from the Register of European Patents

EP About this file: EP2358894

EP2358894 - TEST FOR PREDICTING NEUTRALIZATION OF ASPARAGINASE ACTIVITY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.11.2014
Database last updated on 26.06.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
Erytech Pharma
60 Avenue Rockefeller
69008 Lyon / FR
[2011/34]
Inventor(s)01 / GODFRIN, Yann
23 rue Henri Gorjus
F-69004 Lyon / FR
 [2011/34]
Representative(s)Colombet, Alain André, et al
Cabinet Lavoix
62, Rue de Bonnel
69448 Lyon Cedex 03 / FR
[N/P]
Former [2014/02]Colombet, Alain André, et al
Cabinet Lavoix
62, rue de Bonnel
69448 Lyon Cedex 03 / FR
Former [2011/34]Colombet, Alain André, et al
Cabinet Lavoix 62, rue de Bonnel
69448 Lyon Cedex 03 / FR
Application number, filing date09747859.806.11.2009
[2011/34]
WO2009EP64793
Priority number, dateFR2008005760407.11.2008         Original published format: FR 0857604
[2011/34]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010052315
Date:14.05.2010
Language:EN
[2010/19]
Type: A1 Application with search report 
No.:EP2358894
Date:24.08.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 14.05.2010 takes the place of the publication of the European patent application.
[2011/34]
Type: B1 Patent specification 
No.:EP2358894
Date:08.01.2014
Language:EN
[2014/02]
Search report(s)International search report - published on:EP14.05.2010
ClassificationIPC:C12Q1/37
[2011/34]
CPC:
C12Q1/34 (EP,US); A61K38/50 (EP,US); A61P35/00 (EP);
A61P35/02 (EP); C12Y305/01001 (EP,US); G01N2333/982 (EP,US);
G01N2800/52 (EP,US); G01N2800/7028 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/34]
Extension statesALNot yet paid
BANot yet paid
RSNot yet paid
TitleGerman:TEST ZUR VORHERSAGE DER NEUTRALISIERUNG VON ASPARAGINASE-AKTIVITÄT[2011/34]
English:TEST FOR PREDICTING NEUTRALIZATION OF ASPARAGINASE ACTIVITY[2011/34]
French:ESSAI POUR LA PRÉDICTION DE LA NEUTRALISATION DE L'ACTIVITÉ DE L'ASPARAGINASE[2011/34]
Entry into regional phase06.05.2011National basic fee paid 
06.05.2011Designation fee(s) paid 
06.05.2011Examination fee paid 
Examination procedure06.05.2011Examination requested  [2011/34]
23.01.2012Amendment by applicant (claims and/or description)
16.05.2012Despatch of a communication from the examining division (Time limit: M06)
26.11.2012Reply to a communication from the examining division
18.07.2013Communication of intention to grant the patent
31.10.2013Fee for grant paid
31.10.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.05.2012
Opposition(s)09.10.2014No opposition filed within time limit [2014/51]
Fees paidRenewal fee
22.11.2011Renewal fee patent year 03
21.11.2012Renewal fee patent year 04
25.11.2013Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU06.11.2009
AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MK08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
TR08.01.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
[2018/30]
Former [2016/33]HU06.11.2009
AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
TR08.01.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/32]HU06.11.2009
AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
TR08.01.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/28]AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/22]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2015/24]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SI08.01.2014
SK08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/50]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SE08.01.2014
SK08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/49]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
RO08.01.2014
SE08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/48]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
SE08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/41]AT08.01.2014
BE08.01.2014
CY08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
SE08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/39]AT08.01.2014
CY08.01.2014
FI08.01.2014
LT08.01.2014
NL08.01.2014
SE08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/37]AT08.01.2014
CY08.01.2014
FI08.01.2014
LT08.01.2014
SE08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/36]LT08.01.2014
NO08.04.2014
IS08.05.2014
Cited inInternational search[AD]FR2873925  (ERYTECH PHARMA SOC PAR ACTIONS [FR]) [AD] 1-17 * the whole document *;
 [XI]  - OGAWA C ET AL, "The ex vivo production of ammonia predicts biologic activity of L-asparaginase in children with ALL", BRITISH JOURNAL OF HAEMATOLOGY, & 48TH ANNUAL SCIENTIFIC MEETING OF THE BRITISH-SOCIETY-FOR-HAEMATOLOGY; GLASGOW, UK; APRIL 07 -09, 2008, (200804), vol. 141, no. Suppl. 1, ISSN 0007-1048, page 96, XP002523664 [X] 1,3,12 * abstract * [I] 14-15
 [XD]  - PANOSYAN EDUARD H ET AL, "Asparaginase antibody and asparaginase activity in children with higher-risk acute lymphoblastic leukemia: Children's Cancer Group Study CCG-1961.", JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY : OFFICIAL JOURNAL OF THE AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY APR 2004, (200404), vol. 26, no. 4, ISSN 1077-4114, pages 217 - 226, XP008105155 [XD] 1,3,12-13 * abstract * * page 225, column RIGHT, paragraphs 1,2 *

DOI:   http://dx.doi.org/10.1097/00043426-200404000-00002
 [XPI]  - DUFOUR EMMANUELLE ET AL, "An Assay to Predict L-Asparaginase Neutralization and Enzyme Loaded Red Blood Cells to Maintain in Vivo Efficacy", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (200811), Database accession no. PREV200900257609, XP002563229 [XP] 1-2,4-5,8 * abstract * [I] 3,6-7,9-17
    [ ] - BLOOD, 50TH ANNUAL MEETING OF THE AMERICAN- SOCIETY-OF-HEMATOLOGY; SAN FRANCISCO, CA, USA; DECEMBER 06 -09, 2008, (200811), vol. 112, no. 11, ISSN 0006-4971, pages 336 - 337
 [AD]  - ORSONNEAU J-L ET AL, "Dosage automatique en cinétique de l'activite L-asparaginase plasmatique en suivi thérapeutique des leucémies aiguës lymphoblastiques", ANNALES DE BIOLOGIE CLINIQUE 2004 SEP-OCT, (200409), vol. 62, no. 5, ISSN 0003-3898, pages 568 - 572, XP002523663 [AD] 1-17 * the whole document *
 [A]  - AVRAMIS VASSILIOS I ET AL, "Pharmacokinetic/pharmacodynamic relationships of asparaginase formulations: the past, the present and recommendations for the future", CLINICAL PHARMACOKINETICS, ADIS INTERNATIONAL LTD., AUCKLAND, NZ, vol. 44, no. 4, ISSN 0312-5963, (20050401), pages 367 - 393, XP008105154 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.2165/00003088-200544040-00003
by applicantFR408667
 WO2007103290
    - WANG ET AL., JOURNAL OF IMMUNOLOGICAL METHODS, vol. 239, no. 200, pages 75 - 83
    - MULLER H.J.; BOOS J., CRIT REV ONCOL/HEMATOL, (1998), no. 28, pages 97 - 113
    - BOOS ET AL., EUROPEAN JOURNAL OF CANCER, (1996), vol. 32, pages 1544 - 1550
    - J.L. ORSONNEAU ET AL., ANN BIOL CLIN, (2004), vol. 62, pages 568 - 72
    - B. WANG ET AL., JOURNAL OF IMMUNOLOGICAL METHODS, (2000), vol. 239, pages 75 - 83
    - M.H. WOO ET AL., LEUKEMIA, (1998), vol. 12, pages 1527 - 1533
    - OGAWA C. ET AL., BRITISH JOURNAL OF HAEMATOLOGY, vol. 141, no. 1, pages 1 - 121
    - E.H. PANOSYAN ET AL., J. PEDIATR. HEMATOL. ONCOL., (2004), vol. 26, no. 4, pages 217 - 226
    - ORSONNEAU ET AL., "Automatic kinetic assay of plasma L-asparaginase activity in therapeutic monitoring of acute lymphoblastic leukaemias", ANN BIOL CLIN, vol. 62, pages 568 - 572
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.