EP2318013 - SYNTHESIS AND FORMULATIONS OF SALTS OF ISOPHOSPHORAMIDE MUSTARD AND ANALOGS THEREOF [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 21.04.2017 Database last updated on 19.10.2024 | |
Former | Examination is in progress Status updated on 11.01.2017 | Most recent event Tooltip | 21.04.2017 | Application deemed to be withdrawn | published on 24.05.2017 [2017/21] | Applicant(s) | For all designated states ZIOPHARM ONCOLOGY, INC. One First Avenue Parris Building No. 34 Navy Yard Plaza Boston, MA 02129 / US | [2011/19] | Inventor(s) | 01 /
WALIGORA, Frank, Walter 93 Powder House Avenue Haverhill MD 01830 / US | 02 /
AMEDIO, John, C., Jr. 6 Ginny Lane Franklin MA 02038-4116 / US | [2011/19] | Representative(s) | Dörries, Hans Ulrich, et al df-mp Dörries Frank-Molnia & Pohlman Patentanwälte Rechtsanwälte PartG mbB Theatinerstrasse 16 80333 München / DE | [N/P] |
Former [2011/19] | Dörries, Hans Ulrich, et al df-mp Fünf Höfe Theatinerstrasse 16 80333 München / DE | Application number, filing date | 09803607.2 | 30.07.2009 | [2011/19] | WO2009US52295 | Priority number, date | US20080137538P | 31.07.2008 Original published format: US 137538 P | [2011/19] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2010014841 | Date: | 04.02.2010 | Language: | EN | [2010/05] | Type: | A1 Application with search report | No.: | EP2318013 | Date: | 11.05.2011 | Language: | EN | The application published by WIPO in one of the EPO official languages on 04.02.2010 takes the place of the publication of the European patent application. | [2011/19] | Search report(s) | International search report - published on: | AU | 04.02.2010 | (Supplementary) European search report - dispatched on: | EP | 25.06.2013 | Classification | IPC: | A61K31/675, A61K31/66, A61P35/00, C07F9/22, C07F9/24, C07F9/20 | [2013/30] | CPC: |
C07F9/222 (EP,CN,US);
A61K31/664 (EP,CN,US);
A61K31/66 (EP,US);
A61K31/675 (EP,US);
A61K47/38 (CN);
A61K9/0053 (CN);
A61P35/00 (EP);
A61P9/00 (EP);
C07F9/14 (CN);
C07F9/1406 (US);
C07F9/20 (EP,US);
C07F9/22 (EP,US);
|
Former IPC [2011/19] | A61K31/675, A61K31/66, A61P35/00, C07F9/22 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2011/19] | Title | German: | SYNTHESE UND SALZFORMULIERUNGEN AUS ISOPHOSPHORAMID-SENFGAS UND ANALOGA DAVON | [2011/19] | English: | SYNTHESIS AND FORMULATIONS OF SALTS OF ISOPHOSPHORAMIDE MUSTARD AND ANALOGS THEREOF | [2011/19] | French: | SYNTHÈSE ET FORMULATIONS DE SELS DE MOUTARDE D'ISOPHOSPHORAMIDE ET DE LEURS ANALOGUES | [2011/19] | Entry into regional phase | 28.02.2011 | National basic fee paid | 28.02.2011 | Search fee paid | 28.02.2011 | Designation fee(s) paid | 28.02.2011 | Examination fee paid | Examination procedure | 28.02.2011 | Examination requested [2011/19] | 20.01.2014 | Amendment by applicant (claims and/or description) | 05.08.2016 | Despatch of a communication from the examining division (Time limit: M04) | 16.12.2016 | Application deemed to be withdrawn, date of legal effect [2017/21] | 12.01.2017 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2017/21] | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 05.08.2016 | Fees paid | Renewal fee | 25.07.2011 | Renewal fee patent year 03 | 25.07.2012 | Renewal fee patent year 04 | 27.08.2013 | Renewal fee patent year 05 | 28.07.2014 | Renewal fee patent year 06 | 27.07.2015 | Renewal fee patent year 07 | Penalty fee | Additional fee for renewal fee | 31.07.2013 | 05   M06   Fee paid on   27.08.2013 | 31.07.2016 | 08   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]WO0071134 (SOUTHERN RES INST [US], et al) [X] 1-10,15,16 * claim 1 *; | [X]WO2006047575 (DEKK TEC INC [US], et al) [X] 1-10,15,16 * paragraph [0058] - paragraph [0070]; claim 1 *; | [XP]WO2008124097 (ZIOPHARM ONCOLOGY INC [US], et al) [XP] 1-10,15,16 * claims 1,20,21,36 *; | [A] - GERMANN N ET AL, "Comparative preclinical toxicology and pharmacology of isophosphoramide mustard, the active metabolite of ifosfamide", CANCER CHEMOTHERAPY AND PHARMACOLOGY, SPRINGER VERLAG, BERLIN, vol. 55, no. 2, doi:10.1007/S00280-004-0894-Y, ISSN 0344-5704, (20050101), pages 143 - 151, (20040914), XP002481280 [A] 1-10,15,16 * abstract * DOI: http://dx.doi.org/10.1007/s00280-004-0894-y | International search | SU427945 [ ] (INSTITUTE OF HETEROORGANIC COMPOUNDS); | [X]WO2006047575 (DEKK TEC INC [US], et al); | [X] - MISIURA, K ET AL., "'Isophosphoramide mustard analogues as prodrugs for anti-cancer gene-directed enzyme-prodrug therapy (GDEPT)", ACTA BIOCHIMICA POLONICA, (2002), vol. 49, no. 1, pages 169 - 176, XP008142830 | [X] - HAN, S.Y. ET AL., "Synthesis of O (and O) Labelled Isophosphoramide Mustard", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, (1994), vol. XXXIV, no. 3, pages 247 - 254, XP008142829 DOI: http://dx.doi.org/10.1002/jlcr.2580340307 | [X] - CHEMICAL ABSTRACTS, Database accession no. 81:37378, XP008143854 | [X] - ZAKHAROV, S. ET AL., "Catalytic phosphorylation of polyfluoroalkanols. Communication 5. Catalytic phosphorylation of a-polyfluoroalkylbenzyl alcohols with phosphoryl chloride", BULLETIN OF THE ACADEMY OF SCIENCES OF THE USSR, (1976), vol. 25, no. 8, pages 1727 - 1731, XP008142866 |