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Extract from the Register of European Patents

EP About this file: EP2313111

EP2313111 - TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.07.2014
Database last updated on 25.09.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK
published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
VentiRx Pharmaceuticals, Inc.
1191 Second Avenue, Suite 1105
Seattle, WA 98101 / US
[2014/01]
Former [2011/17]For all designated states
Ventirx Pharmaceuticals, Inc.
12651 High Bluff Drive Suite 200
San Diego, CA 92130 / US
Inventor(s)01 / HOWBERT, J., Jeffry
6106 232nd Avenue NE
Redmond, WA 98053 / US
02 / DUVVURI, Muralikrishna
104 Bristol Drive
Chapel Hill, NC 27516 / US
03 / HERSHBERG, Rob
900 Lenora Street, 1103
Seattle, WA 98121 / US
04 / DIETSCH, Greg
17732 105th Avenue SE
Snohomish, WA 98296 / US
 [2011/30]
Former [2011/21]01 / HOWBERT, J., Jeffry
6106 232nd Avenue NE
Redmond, WA 98053 / US
02 / DUVVURI, Muralikrishna
5544 Sunlight Drive, 288
Durham, NC 27707 / US
03 / HERSHBERG, Rob
900 Lenora Street, 1103
Seattle, WA 98121 / US
04 / DIETSCH, Greg
17732 105th Avenue SE
Snohomish, WA 98296 / US
Former [2011/19]01 / HOWBERT, J., Jeffry
6106 232nd Avenue NE
Redmond, WA 98053 / US
02 / DUVVURI, Muralikrishna
5544 Sunlight Drive, 208
Durham, NC 27707 / US
03 / HERSHBERG, Rob
910 Lenora Street, S905
Seattle, WA 98121 / US
04 / DIETSCH, Greg
17732 105th Avenue SE
Snohomish, WA 98296 / US
Former [2011/17]01 / HOWBERT, J., Jeffry
6106 232nd Avenue NE
Redmond Washington 98053 / US
02 / DUVVURI, Muralikrishna
5544 Sunlight Drive 208
Durham NC 27707 / US
03 / HERSHBERG, Rob
910 Lenora Street S905
Seattle WA 98121 / US
04 / DIETSCH, Greg
17732 105th Avenue SE
Snohomish WA 98296 / US
Representative(s)Mintz Levin Cohn Ferris Glovsky and Popeo LLP
Alder Castle
10 Noble Street
London EC2V 7JX / GB
[2013/15]
Former [2011/17]Crump, Julian Richard John, et al
Mintz Levin Cohn Ferris Glovsky & Popeo Intellectual Property LLP Alder Castle 10 Noble Street
London EC2V 7JX / GB
Application number, filing date09803657.731.07.2009
[2011/17]
WO2009US52422
Priority number, dateUS20080137694P01.08.2008         Original published format: US 137694 P
[2011/17]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010014913
Date:04.02.2010
Language:EN
[2010/05]
Type: A1 Application with search report 
No.:EP2313111
Date:27.04.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 04.02.2010 takes the place of the publication of the European patent application.
[2011/17]
Type: B1 Patent specification 
No.:EP2313111
Date:04.09.2013
Language:EN
[2013/36]
Search report(s)International search report - published on:US04.02.2010
(Supplementary) European search report - dispatched on:EP26.07.2011
ClassificationIPC:A61K9/08, A61K31/724, A61K47/00, A61K9/00, A61K9/19, // A61K31/395, A61K47/48, A61P35/00, A61P31/12
[2013/12]
CPC:
A61K31/55 (EP,US); A61K31/724 (EP,US); A61K47/40 (US);
A61K47/6951 (EP,US); A61K9/0019 (EP,US); A61K9/08 (EP,US);
A61K9/19 (EP,US); A61P17/00 (EP); A61P31/00 (EP);
A61P31/12 (EP); A61P35/00 (EP); A61P37/08 (EP);
B82Y5/00 (EP,US); C07D223/16 (EP,US); C08B37/0012 (EP,US);
Y02A50/30 (EP,US) (-)
Former IPC [2011/17]A61K39/395
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/17]
TitleGerman:TOLL-REZEPTORAGONISTEN-FORMULIERUNGEN UND IHRE VERWENDUNG[2011/17]
English:TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE[2011/17]
French:FORMULATIONS D'AGONISTE DES RÉCEPTEURS DE TYPE TOLL ET LEUR UTILISATION[2011/17]
Entry into regional phase31.01.2011National basic fee paid 
31.01.2011Search fee paid 
31.01.2011Designation fee(s) paid 
31.01.2011Examination fee paid 
Examination procedure31.01.2011Examination requested  [2011/17]
13.02.2012Amendment by applicant (claims and/or description)
09.03.2012Despatch of a communication from the examining division (Time limit: M04)
13.07.2012Reply to a communication from the examining division
27.03.2013Communication of intention to grant the patent
16.07.2013Fee for grant paid
16.07.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.03.2012
Opposition(s)05.06.2014No opposition filed within time limit [2014/33]
Fees paidRenewal fee
25.07.2011Renewal fee patent year 03
25.07.2012Renewal fee patent year 04
29.07.2013Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBG04.09.2013
CY04.09.2013
EE04.09.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
MK04.09.2013
MT04.09.2013
RO04.09.2013
SI04.09.2013
SK04.09.2013
SM04.09.2013
GR05.12.2013
IS04.01.2014
[2018/30]
Former [2016/28]BG04.09.2013
CY04.09.2013
EE04.09.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
MT04.09.2013
RO04.09.2013
SI04.09.2013
SK04.09.2013
SM04.09.2013
GR05.12.2013
IS04.01.2014
Former [2016/22]CY04.09.2013
EE04.09.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
RO04.09.2013
SI04.09.2013
SK04.09.2013
SM04.09.2013
GR05.12.2013
IS04.01.2014
Former [2014/23]CY04.09.2013
EE04.09.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
RO04.09.2013
SI04.09.2013
SK04.09.2013
GR05.12.2013
IS04.01.2014
Former [2014/22]CY04.09.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
RO04.09.2013
SI04.09.2013
GR05.12.2013
Former [2014/18]CY04.09.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
SI04.09.2013
GR05.12.2013
Former [2014/12]CY17.07.2013
HR04.09.2013
LT04.09.2013
LV04.09.2013
SI04.09.2013
GR05.12.2013
Former [2014/10]CY17.07.2013
HR04.09.2013
LT04.09.2013
Former [2014/09]HR04.09.2013
LT04.09.2013
Former [2014/08]LT04.09.2013
Documents cited:Search[XY]WO9612493  (MERCK & CO INC [US], et al) [X] 1,7,8,10,11 * See page 2, second paragraph: beta cyclodextrin compositions for increasing bioavailability and absorption of pharmaceutically active compounds. See examples 1-7: compositions comprising beta cyclodextrin and a benzoazepine compound. See claim 2: use to treat HIV * [Y] 1-15;
 [XY]WO9855148  (JANSSEN PHARMACEUTICA NV [BE], et al) [X] 1,7,8,10 * See page 2, lines 4-20; page 5, lines 30-35; examples 2, 8: pharmaceutical compositions comprising a b-benzoazepine and a cyclodextrin as solubility enhancer * [Y] 1-15;
 [Y]  - RAJEWSKI R A ET AL, "PHARMACEUTICAL APPLICATIONS OF CYCLODEXTRINS. 2. IN VIVO DRUG DELIVERY", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, (19961101), vol. 85, no. 11, doi:10.1021/JS960075U, ISSN 0022-3549, pages 1142 - 1169, XP000629515 [Y] 1-15 * See abstract and table 1: beta cyclodextrin and sulfobutylether of cyclodextrin for use in drug delivery for parenteral and other delivery routes *

DOI:   http://dx.doi.org/10.1021/js960075u
 [Y]  - CHALLA R ET AL, "Cyclodextrins in drug delivery: an updated review", AAPS PHARMSCITECH, SPRINGER NEW YORK LLC, US, (20051014), vol. 6, no. 2, doi:10.1208/PT060243, ISSN 1530-9932, pages E329 - E357, XP008136705 [Y] 1-15 * See abstract and table 1: beta cyclodextrin and sulfobutylether of cyclodextrin for use in drug delivery systems. See page E337: effects on drug stability *

DOI:   http://dx.doi.org/10.1208/pt060243
International search[Y]WO2007024612  (ARRAY BIOPHARMA INC [US], et al);
 [Y]US2007197478  (JONES PETER [GB], et al);
 [Y]US2008008682  (CHONG LEE S [US], et al)
by applicantUS4120649
 US4665077
 WO2007024612
    - MAIONE ET AL., CANCER RES., (1990), vol. 51, pages 2077 - 2083
    - TOLMA ET AL., J. CELL IOL., (1993), vol. 122, pages 497 - 511
    - TOLSMA ET AL., J. CELL BIOL., (1993), vol. 122, pages 497 - 511
    - SAGE ET AL., J. CELL. BIOCHEM., (1995), vol. 57, pages 1329 - 1334
    - CAO, PROG MOL SUBCELL BID., (1998), vol. 20, pages 161 - 176
    - BROOKS ET AL., SCIENCE, (1994), vol. 264, pages 569 - 571
    - HAMMES ET AL., NATURE MEDICINE, (1996), vol. 2, pages 529 - 533
    - MIN ET AL., CANCER RES., (1996), vol. 56, pages 2428 - 33
    - CROWLEY ET AL., PROC NATL ACAD SCI., (1993), vol. 90, pages 5021 - 25
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.