EP2355807 - INHIBITORS OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 28.06.2019 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 20.07.2018 | ||
Former | Grant of patent is intended Status updated on 16.07.2018 | ||
Former | Examination is in progress Status updated on 27.06.2018 | ||
Former | Grant of patent is intended Status updated on 12.02.2018 | ||
Former | Examination is in progress Status updated on 29.05.2017 | Most recent event Tooltip | 03.07.2020 | Lapse of the patent in a contracting state New state(s): CY, MK | published on 05.08.2020 [2020/32] | Applicant(s) | For all designated states Christian-Albrechts-Universität zu Kiel Christian-Albrechts-Platz 4 24118 Kiel / DE | [2018/34] |
Former [2011/33] | For all designated states Christian-Albrechts-Universität zu Kiel Christian-Albrechts-Platz 4 24118 Kiel / DE | Inventor(s) | 01 /
CLEMENT, Bernd Johann-Fleck-Str. 27 24106 Kiel / DE | 02 /
KOTTHAUS, Jürke Westring 341 24118 Kiel / DE | 03 /
SCHADE, Dennis Speckenstr. 2 27632 Dorum / DE | [2012/01] |
Former [2011/33] | 01 /
CLEMENT, Bernd Johann-Fleck-Str. 27 24106 Kiel / DE | ||
02 /
KOTTHAUS, Jürke Wilhelmstrasse 7 24116 Kiel / DE | |||
03 /
SCHADE, Dennis Hasseldieksdammer Weg 5 24114 Kiel / DE | Representative(s) | Steinecke, Peter Müller Fottner Steinecke Rechtsanwalts- und Patentanwaltspartnerschaft mbB Römerstrasse 16 b 52428 Jülich / DE | [2018/34] |
Former [2012/01] | Steinecke, Peter Müller Fottner Steinecke Rechtsanwälte - Patentanwälte Technologiezentrum Jülich Karl-Heinz-Beckurts-Strasse 13 52428 Jülich / DE | ||
Former [2011/33] | Lobemeier, Martin Landolf Boehmert & Boehmert Anwaltssozietät Niemannsweg 133 24105 Kiel / DE | Application number, filing date | 09804240.1 | 08.12.2009 | [2011/33] | WO2009DE01724 | Priority number, date | DE20081061247 | 10.12.2008 Original published format: DE102008061247 | [2011/33] | Filing language | DE | Procedural language | DE | Publication | Type: | A1 Application with search report | No.: | WO2010066239 | Date: | 17.06.2010 | Language: | DE | [2010/24] | Type: | A1 Application with search report | No.: | EP2355807 | Date: | 17.08.2011 | Language: | DE | The application published by WIPO in one of the EPO official languages on 17.06.2010 takes the place of the publication of the European patent application. | [2011/33] | Type: | B1 Patent specification | No.: | EP2355807 | Date: | 22.08.2018 | Language: | DE | [2018/34] | Search report(s) | International search report - published on: | EP | 17.06.2010 | Classification | IPC: | A61K31/155, A61K31/17, A61P9/00, A61P9/02, A61P9/10, A61P11/06, A61P25/00, A61P25/06, A61P29/00, A61P31/04, A61P35/00, C07C257/14, C07C279/12 | [2018/09] | CPC: |
A61K31/155 (EP,US);
A61K31/17 (EP,US);
A61P11/06 (EP);
A61P25/00 (EP);
A61P25/06 (EP);
A61P25/28 (EP);
A61P29/00 (EP);
A61P31/04 (EP);
A61P35/00 (EP);
A61P7/00 (EP);
A61P9/00 (EP);
A61P9/02 (EP);
|
Former IPC [2011/33] | A61K31/00, A61K31/155, A61K31/17, A61P9/00, A61P9/02, A61P9/10, A61P11/06, A61P25/00, A61P25/06, A61P29/00, A61P31/04, A61P35/00 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2018/34] |
Former [2011/33] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR | Extension states | AL | Not yet paid | BA | Not yet paid | RS | Not yet paid | Title | German: | INHIBITOREN DER DIMETHYLARGININ DIMETHYLAMINOHYDROLASE | [2011/33] | English: | INHIBITORS OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE | [2011/33] | French: | INHIBITEURS DE LA DIMÉTHYLARGININE DIMÉTHYLAMINOHYDROLASE | [2011/33] | Entry into regional phase | 15.03.2011 | National basic fee paid | 15.03.2011 | Designation fee(s) paid | 15.03.2011 | Examination fee paid | Examination procedure | 15.03.2011 | Examination requested [2011/33] | 27.01.2012 | Amendment by applicant (claims and/or description) | 10.07.2015 | Despatch of a communication from the examining division (Time limit: M04) | 19.11.2015 | Reply to a communication from the examining division | 18.05.2017 | Despatch of a communication from the examining division (Time limit: M06) | 21.11.2017 | Reply to a communication from the examining division | 13.02.2018 | Communication of intention to grant the patent | 22.06.2018 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 22.06.2018 | Fee for grant paid | 22.06.2018 | Fee for publishing/printing paid | 16.07.2018 | Information about intention to grant a patent | 16.07.2018 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 10.07.2015 | Opposition(s) | 23.05.2019 | No opposition filed within time limit [2019/31] | Fees paid | Renewal fee | 23.12.2011 | Renewal fee patent year 03 | 19.12.2012 | Renewal fee patent year 04 | 27.12.2013 | Renewal fee patent year 05 | 22.12.2014 | Renewal fee patent year 06 | 22.12.2015 | Renewal fee patent year 07 | 29.12.2016 | Renewal fee patent year 08 | 28.12.2017 | Renewal fee patent year 09 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 08.12.2009 | CY | 22.08.2018 | CZ | 22.08.2018 | DK | 22.08.2018 | EE | 22.08.2018 | ES | 22.08.2018 | FI | 22.08.2018 | HR | 22.08.2018 | IT | 22.08.2018 | LT | 22.08.2018 | LV | 22.08.2018 | MC | 22.08.2018 | MK | 22.08.2018 | MT | 22.08.2018 | NL | 22.08.2018 | PL | 22.08.2018 | PT | 22.08.2018 | RO | 22.08.2018 | SE | 22.08.2018 | SI | 22.08.2018 | SK | 22.08.2018 | SM | 22.08.2018 | TR | 22.08.2018 | BG | 22.11.2018 | NO | 22.11.2018 | GR | 23.11.2018 | AT | 08.12.2018 | IE | 08.12.2018 | LU | 08.12.2018 | IS | 22.12.2018 | BE | 31.12.2018 | [2020/31] |
Former [2020/30] | HU | 08.12.2009 | |
CZ | 22.08.2018 | ||
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
MT | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
PT | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
TR | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
AT | 08.12.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
BE | 31.12.2018 | ||
Former [2020/27] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
MT | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
PT | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
TR | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
AT | 08.12.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
BE | 31.12.2018 | ||
Former [2020/23] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
MT | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
TR | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
AT | 08.12.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
BE | 31.12.2018 | ||
Former [2020/17] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
MT | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
TR | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
BE | 31.12.2018 | ||
Former [2020/08] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
MT | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
BE | 31.12.2018 | ||
Former [2019/51] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
BE | 31.12.2018 | ||
Former [2019/48] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IE | 08.12.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
Former [2019/40] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
MC | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
Former [2019/39] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
LU | 08.12.2018 | ||
IS | 22.12.2018 | ||
Former [2019/37] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SI | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/26] | CZ | 22.08.2018 | |
DK | 22.08.2018 | ||
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SK | 22.08.2018 | ||
SM | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/24] | CZ | 22.08.2018 | |
EE | 22.08.2018 | ||
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
SK | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/22] | CZ | 22.08.2018 | |
ES | 22.08.2018 | ||
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
PL | 22.08.2018 | ||
RO | 22.08.2018 | ||
SE | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/21] | ES | 22.08.2018 | |
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
IT | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
SE | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/12] | ES | 22.08.2018 | |
FI | 22.08.2018 | ||
HR | 22.08.2018 | ||
LT | 22.08.2018 | ||
LV | 22.08.2018 | ||
NL | 22.08.2018 | ||
SE | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/11] | FI | 22.08.2018 | |
HR | 22.08.2018 | ||
LT | 22.08.2018 | ||
NL | 22.08.2018 | ||
SE | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/10] | FI | 22.08.2018 | |
LT | 22.08.2018 | ||
NL | 22.08.2018 | ||
SE | 22.08.2018 | ||
BG | 22.11.2018 | ||
NO | 22.11.2018 | ||
GR | 23.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/09] | FI | 22.08.2018 | |
LT | 22.08.2018 | ||
NL | 22.08.2018 | ||
NO | 22.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/08] | FI | 22.08.2018 | |
LT | 22.08.2018 | ||
NO | 22.11.2018 | ||
IS | 22.12.2018 | ||
Former [2019/07] | LT | 22.08.2018 | Cited in | International search | [X]EP0330629 (CONSIGLIO NAZIONALE RICERCHE [IT]) [X] 1,3-7 * abstract * * page 24, lines 14-23 *; | [X]WO9304048 (BOEHRINGER INGELHEIM INT [DE], et al) [X] 1,3-7 * abstract * * page 20, paragraph last - page 11, paragraph 1 *; | [A]WO9732844 (SEARLE & CO [US], et al) [A] 1-8 * abstract *; | [X]WO2006051314 (UCL BIOMEDICA PLC [GB], et al) [X] 1,4-8 * abstract * * page 1, lines 4-6 * * page 4, lines 10-12 * * page 18, line 16 - page 19, line 25 * * page 19, lines 3-12 * * page 23, lines 4-10 * * page 27, line 1 - page 32, line 22; examples 22-30; tables 1, 2, 3,4 * * figures 1,3; example 28; compound SR291 *; | [XI] - ROBERTSON J G ET AL, "Inhibition of Bovine Brain Nitric Oxide Synthase by alpha-Amino and alpha-Carboxyl Derivatives of N-Allyl-L-arginine", BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC., NEW YORK, NY, US LNKD- DOI:10.1006/BIOO.1995.1012, (19950101), vol. 23, ISSN 0045-2068, pages 144 - 151, XP002374532 [X] 1,3-6 * abstract * * NG-Allyl-L-arginine methyl ester * [I] 7 DOI: http://dx.doi.org/10.1006/bioo.1995.1012 | [AP] - KOTTHAUS J ET AL, "Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: Alkenyl-amidines as new leads", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB LNKD- DOI:10.1016/J.BMC.2008.10.058, vol. 16, no. 24, ISSN 0968-0896, (20081215), pages 10205 - 10209, (20081029), XP025685109 [AP] 1-8 * abstract * DOI: http://dx.doi.org/10.1016/j.bmc.2008.10.058 | by applicant | DE4321444 | - CLEMENT, B., "Methoden zur Behandlung und Prophylaxe der Pneomocystis carinii Pneumonie (PCP) und anderen Erkrankungen sowie Verbindungen und Formulierungen zum Gebrauch bei besagten", METHODEN. P., (1993), page 432444.4 | WO2007DE01216 |