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Extract from the Register of European Patents

EP About this file: EP2334800

EP2334800 - MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  01.11.2019
Database last updated on 03.09.2024
FormerThe patent has been granted
Status updated on  23.11.2018
FormerGrant of patent is intended
Status updated on  24.07.2018
FormerExamination is in progress
Status updated on  13.06.2018
FormerGrant of patent is intended
Status updated on  21.02.2018
FormerExamination is in progress
Status updated on  07.11.2016
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK
published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Genomatica, Inc.
4757 Nexus Center Drive
San Diego, CA 92121 / US
[2014/52]
Former [2011/25]For all designated states
Genomatica, Inc.
10520 Wateridge Circle
San Diego, CA 92121 / US
Inventor(s)01 / BURK, Mark, J.
12634 Intermezzo Way
San Diego, CA 92130 / US
02 / BURGARD, Anthony, P.
237 Walker Crossing
Bellefonte, PA 16823 / US
03 / OSTERHOUT, Robin, E.
4910 Orchard Avenue
San Diego, CA 92107 / US
04 / SUN, Jun
8274 Bryn Glen Way
San Diego, CA 92129 / US
 [2011/25]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2018/52]
Former [2013/33]HOFFMANN EITLE
Patent- und Rechtsanwälte
Arabellastrasse 4
81925 München / DE
Former [2011/25]Jones Day
Rechtsanwälte, Attorneys-at-Law, Patentanwälte Prinzregentenstrasse 11
80538 München / DE
Application number, filing date09813563.509.09.2009
[2011/25]
WO2009US56415
Priority number, dateUS20080191710P10.09.2008         Original published format: US 191710 P
US20080192511P17.09.2008         Original published format: US 192511 P
[2011/25]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010030711
Date:18.03.2010
Language:EN
[2010/11]
Type: A2 Application without search report 
No.:EP2334800
Date:22.06.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 18.03.2010 takes the place of the publication of the European patent application.
[2011/25]
Type: B1 Patent specification 
No.:EP2334800
Date:26.12.2018
Language:EN
[2018/52]
Search report(s)International search report - published on:US07.10.2010
(Supplementary) European search report - dispatched on:EP23.07.2012
ClassificationIPC:C12N9/00, C12N9/02, C12N9/04, C12N9/10, C12N9/12, C12N9/16, C12N9/88, C12N9/90, C12N15/52, C12N15/70, C12N15/81, C12P7/18
[2018/08]
CPC:
C12P7/18 (EP,US); B01D3/002 (EP,US); C12N15/52 (EP,US);
C12N15/70 (EP,US); C12N15/81 (EP,US); C12N9/0006 (EP,US);
C12N9/0008 (EP,US); C12N9/001 (EP,US); C12N9/1029 (EP,US);
C12N9/1096 (EP,US); C12N9/12 (EP,US); C12N9/13 (EP,US);
C12N9/16 (EP,US); C12N9/88 (EP,US); C12N9/90 (EP,US);
C12N9/93 (EP,US); C12Y101/01157 (EP,US); C12Y402/01055 (EP,US);
Y02E50/10 (EP) (-)
Former IPC [2011/25]C12P7/16, C12P1/04
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2018/52]
Former [2011/25]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
Extension statesALNot yet paid
BANot yet paid
RSNot yet paid
TitleGerman:MIKROORGANISMEN ZUR HERSTELLUNG VON 1,4-BUTANDIOL[2011/25]
English:MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL[2011/25]
French:MICROORGANISMES POUR LA PRODUCTION DE 1,4-BUTANEDIOL[2011/25]
Entry into regional phase08.04.2011National basic fee paid 
08.04.2011Search fee paid 
08.04.2011Designation fee(s) paid 
08.04.2011Examination fee paid 
Examination procedure08.04.2011Examination requested  [2011/25]
19.02.2013Amendment by applicant (claims and/or description)
03.07.2013Despatch of a communication from the examining division (Time limit: M06)
13.01.2014Reply to a communication from the examining division
28.04.2016Despatch of a communication from the examining division (Time limit: M06)
07.11.2016Reply to a communication from the examining division
05.07.2017Despatch of a communication from the examining division (Time limit: M06)
11.01.2018Reply to a communication from the examining division
22.02.2018Communication of intention to grant the patent
11.06.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
25.07.2018Communication of intention to grant the patent
13.11.2018Fee for grant paid
13.11.2018Fee for publishing/printing paid
13.11.2018Receipt of the translation of the claim(s)
Divisional application(s)EP18214553.2  / EP3514242
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  03.07.2013
Opposition(s)27.09.2019No opposition filed within time limit [2019/49]
Fees paidRenewal fee
29.09.2011Renewal fee patent year 03
12.09.2012Renewal fee patent year 04
12.09.2013Renewal fee patent year 05
12.09.2014Renewal fee patent year 06
11.09.2015Renewal fee patent year 07
13.09.2016Renewal fee patent year 08
12.09.2017Renewal fee patent year 09
11.09.2018Renewal fee patent year 10
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Lapses during opposition  TooltipHU09.09.2009
AT26.12.2018
CY26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
MK26.12.2018
MT26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
IE09.09.2019
IT09.09.2019
LU09.09.2019
[2022/31]
Former [2021/34]HU09.09.2009
AT26.12.2018
CY26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
MT26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
IE09.09.2019
IT09.09.2019
LU09.09.2019
Former [2021/32]HU09.09.2009
AT26.12.2018
CY26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
IE09.09.2019
IT09.09.2019
LU09.09.2019
Former [2021/26]AT26.12.2018
CY26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
IE09.09.2019
IT09.09.2019
LU09.09.2019
Former [2020/39]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
IE09.09.2019
IT09.09.2019
LU09.09.2019
Former [2020/36]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
IE09.09.2019
LU09.09.2019
Former [2020/35]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
LU09.09.2019
Former [2020/25]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
MC26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
Former [2020/17]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
TR26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
Former [2020/13]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SI26.12.2018
SK26.12.2018
SM26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
Former [2019/48]AT26.12.2018
CZ26.12.2018
DK26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SK26.12.2018
SM26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
Former [2019/46]AT26.12.2018
CZ26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SK26.12.2018
SM26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
Former [2019/39]CZ26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SK26.12.2018
SM26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
IS26.04.2019
PT26.04.2019
Former [2019/37]CZ26.12.2018
EE26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
RO26.12.2018
SE26.12.2018
SM26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
PT26.04.2019
Former [2019/35]CZ26.12.2018
ES26.12.2018
FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
PL26.12.2018
SE26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
PT26.04.2019
Former [2019/33]FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
SE26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
PT26.04.2019
Former [2019/24]FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
SE26.12.2018
BG26.03.2019
NO26.03.2019
GR27.03.2019
Former [2019/23]FI26.12.2018
HR26.12.2018
LT26.12.2018
LV26.12.2018
BG26.03.2019
NO26.03.2019
Former [2019/22]FI26.12.2018
LT26.12.2018
BG26.03.2019
NO26.03.2019
Former [2019/21]FI26.12.2018
LT26.12.2018
NO26.03.2019
Former [2019/20]LT26.12.2018
NO26.03.2019
Documents cited:Search[A]KR20070096348  (LG CHEMICAL LTD [KR], et al) [A] 1,2,10,12-16* claims 1-30 *;
 [E]WO2010006076  (OPX BIOTECHNOLOGIES INC [US], et al) [E] 1 * paragraph [00169]; claims 1,4,6,11 *
International search[A]JPS62285779  (CHIYODA CHEM ENG CONSTRUCT CO);
 [A]WO0061763  (UNIV GUELPH [CA], et al);
 [X]US2007190605  (BESSLER CORNELIUS [DE], et al);
 [A]US2008138870  (BRAMUCCI MICHAEL G [US], et al);
 [A]US2008182308  (DONALDSON GAIL K [US], et al);
 [XE]US2009047719  (BURGARD ANTHONY P [US], et al);
 [XE]WO2009094485  (GENOMATICA INC [US], et al);
 [X]  - GERHARDT ET AL., "Fermentation of 4-aminobutyrate by Clostridium aminobutyricum: cloning of two genes involved in the formation and dehydration of 4-hydroxybutyryl-CoA.", ARCH. MICROBIOL., (2000), vol. 174, no. 3, pages 189 - 199, XP008109904

DOI:   http://dx.doi.org/10.1007/s002030000195
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DOI:   http://dx.doi.org/10.1007/s00253-007-1057-y
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DOI:   http://dx.doi.org/10.1093/bioinformatics/btm575
 [A]  - JEWELL ET AL., "Bioconversion of Propionic, Valeric, and 4-Hydroxybutyric Acids into the Corresponding Alcohols by Clostridium acetobutylicum NRRL 537.", CURR. MICROBIOL., (1986), vol. 13, pages 215 - 219, XP008139685
 [AP]  - CUKALOVIC ET AL., "Feasibility of production method for succinic acid derivatives: a marriage of renewable resources and chemical technology.", BIOFUELS BIOPROD. BIOREF., (20081013), vol. 2, pages 505 - 529, XP008139686

DOI:   http://dx.doi.org/10.1002/bbb.105
 [A]  - FEIST ET AL., "The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli.", NAT. BIOTECHNOL., (200806), vol. 26, no. 6, pages 659 - 667, XP008139687

DOI:   http://dx.doi.org/10.1038/nbt1401
 [A]  - WANG ET AL., "Screening microorganisms for utilization of furfural and possible intermediates in its degradative pathway.", BIOTECHNOL. LETT., (1994), vol. 16, no. 9, pages 977 - 982, XP008139688
 [A]  - OKINO ET AL., "An efficient succinic acid production process in a metabolically engineered Corynebacterium glutamicum strain.", APPL. MICROBIOL. BIOTECHNOL., (20080906), vol. 81, no. 3, pages 459 - 464, XP019654155

DOI:   http://dx.doi.org/10.1007/s00253-008-1668-y
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.