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Extract from the Register of European Patents

EP About this file: EP2376090

EP2376090 - INHIBITION OF APOE CLEAVAGE ACTIVITY IN THE TREATMENT OF APOE-RELATED DISORDERS [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  20.09.2013
Database last updated on 03.09.2024
Most recent event   Tooltip20.09.2013Withdrawal of applicationpublished on 23.10.2013  [2013/43]
Applicant(s)For all designated states
The J. David Gladstone Institutes
1650 Owens Street
San Francisco, CA 94158 / US
[2011/42]
Inventor(s)01 / HUANG, Yadong
1718 20th Avenue
San Francisco California 94122 / US
02 / XU, Qin
727 San Pablo Avenue
Albany California 94706 / US
03 / STEELE, Mei Xiu
1641 De Anza Blvd
San Mateo California 94404 / US
04 / MAHLEY, Robert W.
325 Berry Street 327
San Francisco California 94125 / US
05 / WEISGRABER, Karl H.
1018 Rudgear Road
Walnut Creek California 94596 / US
06 / FREEDMAN, Stephen Barry
355 First Street
2301
San Francisco California 94105 / US
 [2011/42]
Representative(s)Brasnett, Adrian Hugh, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2011/42]Brasnett, Adrian Hugh, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Application number, filing date09828290.820.11.2009
WO2009US65335
Priority number, dateUS20080116838P21.11.2008         Original published format: US 116838 P
[2011/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010059942
Date:27.05.2010
Language:EN
[2010/21]
Type: A1 Application with search report 
No.:EP2376090
Date:19.10.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 27.05.2010 takes the place of the publication of the European patent application.
[2011/42]
Search report(s)International search report - published on:US27.05.2010
(Supplementary) European search report - dispatched on:EP26.10.2012
ClassificationIPC:A61K31/7088, A61K38/00, C07K14/775
[2012/48]
CPC:
C12N15/1137 (EP,US); A61K31/7088 (EP,US); A61K45/06 (EP,US);
A61P25/28 (EP); A61P29/00 (EP); A61P43/00 (EP);
A61P9/00 (EP); A61P9/10 (EP); C07K14/775 (EP,US);
C12Y304/21092 (EP,US); G01N33/92 (EP,US); C12N2310/14 (EP,US);
C12N2310/531 (EP,US); G01N2333/96433 (EP,US); G01N2500/02 (EP,US);
G01N2800/2821 (EP,US) (-)
C-Set:
A61K31/7088, A61K2300/00 (EP,US)
Former IPC [2011/42]A61K31/7088, A61K38/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR 
TitleGerman:UNTERDRÜCKUNG DER APOE-SPALTAKTIVITÄT BEI DER BEHANDLUNG VON ERKRANKUNGEN IM ZUSAMMENHANG MIT APOE[2011/45]
English:INHIBITION OF APOE CLEAVAGE ACTIVITY IN THE TREATMENT OF APOE-RELATED DISORDERS[2011/42]
French:INHIBITION DE L 'ACTIVITÉ DE CLIVAGE DE L' APOE DANS LE TRAITEMENT DE TROUBLES ASSOCIÉS À L' APOE[2011/42]
Former [2011/42]UNTERDR?CKUNG DER APOE-SPALTAKTIVIT?T BEI DER BEHANDLUNG VON ERKRANKUNGEN IM ZUSAMMENHANG MIT APOE
Entry into regional phase21.06.2011National basic fee paid 
21.06.2011Search fee paid 
21.06.2011Designation fee(s) paid 
21.06.2011Examination fee paid 
Examination procedure21.06.2011Examination requested  [2011/42]
30.04.2013Amendment by applicant (claims and/or description)
12.09.2013Application withdrawn by applicant  [2013/43]
Fees paidRenewal fee
23.11.2011Renewal fee patent year 03
26.11.2012Renewal fee patent year 04
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Documents cited:Search[I]  - F. M. HARRIS, "Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20030101), vol. 100, no. 19, doi:10.1073/pnas.1434398100, ISSN 0027-8424, pages 10966 - 10971, XP055041569 [I] 1-18 * abstract * * page 10968, column l, paragraph l - column r, paragraph 1; figure 1 *

DOI:   http://dx.doi.org/10.1073/pnas.1434398100
International search[Y]US2002147999  (HUANG YADONG [US], et al);
 [Y]WO2007093042  (ALETHIA BIOTHERAPEUTICS INC [CA], et al)
 [Y]  - ARRIBAS ET AL., "A comparative study of the chymotrypsin-like activity of the rat liver multicatalytic proteinase and the CIpP from Escherichia coli.", J. BIOL. CHEM., (19931005), vol. 268, no. 28, pages 21165 - 21171
 [Y]  - BROSS ET AL., "Human CIpP protease: cDNA sequence, tissue-specific expression and I chromosomal assignment of the gene", FEBS LETT., (19951218), vol. 377, no. 2, pages 249 - 252
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.