EP2369936 - COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF LENS FIBROTIC DISEASES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 30.11.2018 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 22.12.2017 | ||
Former | Grant of patent is intended Status updated on 31.07.2017 | Most recent event Tooltip | 26.06.2020 | Lapse of the patent in a contracting state New state(s): MK | published on 29.07.2020 [2020/31] | Applicant(s) | For all designated states Lankenau Institute for Medical Research 100 East Lancaster Avenue Wynnewood, PA 19096 / US | For all designated states Thomas Jefferson University 1020 Walnut Street Philadelphia, PA 19107 / US | [2012/19] |
Former [2011/40] | For all designated states Lankenau Institute for Medical Research 100 East Lancaster Avenue Wynnewood, PA 19096 / US | Inventor(s) | 01 /
MENKO, Allyn, Sue 205 Standish Road Merion PA 19066 / US | 02 /
GEORGE-WEINSTEIN, Mindy 227 Hemlock Road Wynnewood PA 19096 / US | 03 /
WALKER, Janice, L. 235A Bainbridge Street Philadelphia PA 19147 / US | 04 /
GERHART, Jacquelyn 244 Rockglen Road Wynnewood PA 19096 / US | [2011/40] | Representative(s) | Potter Clarkson Chapel Quarter Mount Street Nottingham NG1 6HQ / GB | [N/P] |
Former [2018/04] | Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG / GB | ||
Former [2013/37] | Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG / GB | ||
Former [2011/40] | Didmon, Mark, et al Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham NG1 5DD / GB | Application number, filing date | 09831240.8 | 04.12.2009 | [2018/04] | WO2009US66859 | Priority number, date | US20080119750P | 04.12.2008 Original published format: US 119750 P | [2011/40] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2010065920 | Date: | 10.06.2010 | Language: | EN | [2010/23] | Type: | A1 Application with search report | No.: | EP2369936 | Date: | 05.10.2011 | Language: | EN | The application published by WIPO in one of the EPO official languages on 10.06.2010 takes the place of the publication of the European patent application. | [2011/40] | Type: | B1 Patent specification | No.: | EP2369936 | Date: | 24.01.2018 | Language: | EN | [2018/04] | Search report(s) | International search report - published on: | US | 10.06.2010 | (Supplementary) European search report - dispatched on: | EP | 07.12.2012 | Classification | IPC: | A01N63/02, A61K39/395 | [2011/40] | CPC: |
C07K16/28 (EP,US);
A61P27/02 (EP);
A61P27/12 (EP);
A61P43/00 (EP);
C07K16/30 (EP,US);
A61K2039/505 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2018/04] | Extension states | AL | Not yet paid | BA | Not yet paid | RS | Not yet paid | Title | German: | ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG UND PRÄVENTION VON FIBROTISCHEN LINSENERKRANKUNGEN | [2011/40] | English: | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF LENS FIBROTIC DISEASES | [2011/40] | French: | COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT PROPHYLACTIQUE ET THÉRAPEUTIQUE DE MALADIES FIBROTIQUES DU CRISTALLIN | [2011/40] | Entry into regional phase | 01.07.2011 | National basic fee paid | 01.07.2011 | Search fee paid | 01.07.2011 | Designation fee(s) paid | 01.07.2011 | Examination fee paid | Examination procedure | 01.07.2011 | Examination requested [2011/40] | 05.07.2013 | Amendment by applicant (claims and/or description) | 06.05.2015 | Despatch of a communication from the examining division (Time limit: M06) | 06.11.2015 | Reply to a communication from the examining division | 21.06.2017 | Cancellation of oral proceeding that was planned for 29.06.2017 | 29.06.2017 | Date of oral proceedings (cancelled) | 01.08.2017 | Communication of intention to grant the patent | 13.11.2017 | Fee for grant paid | 13.11.2017 | Fee for publishing/printing paid | 13.11.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 06.05.2015 | Opposition(s) | 25.10.2018 | No opposition filed within time limit [2019/01] | Fees paid | Renewal fee | 12.12.2011 | Renewal fee patent year 03 | 11.12.2012 | Renewal fee patent year 04 | 12.12.2013 | Renewal fee patent year 05 | 11.12.2014 | Renewal fee patent year 06 | 10.12.2015 | Renewal fee patent year 07 | 13.12.2016 | Renewal fee patent year 08 | 12.12.2017 | Renewal fee patent year 09 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 04.12.2009 | AT | 24.01.2018 | CY | 24.01.2018 | CZ | 24.01.2018 | DK | 24.01.2018 | EE | 24.01.2018 | ES | 24.01.2018 | FI | 24.01.2018 | HR | 24.01.2018 | IT | 24.01.2018 | LT | 24.01.2018 | LV | 24.01.2018 | MC | 24.01.2018 | MK | 24.01.2018 | NL | 24.01.2018 | PL | 24.01.2018 | PT | 24.01.2018 | RO | 24.01.2018 | SE | 24.01.2018 | SI | 24.01.2018 | SK | 24.01.2018 | SM | 24.01.2018 | TR | 24.01.2018 | BG | 24.04.2018 | NO | 24.04.2018 | GR | 25.04.2018 | IS | 24.05.2018 | [2020/31] |
Former [2020/30] | HU | 04.12.2009 | |
AT | 24.01.2018 | ||
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
MC | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
PT | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SI | 24.01.2018 | ||
SK | 24.01.2018 | ||
SM | 24.01.2018 | ||
TR | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2020/27] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
MC | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
PT | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SI | 24.01.2018 | ||
SK | 24.01.2018 | ||
SM | 24.01.2018 | ||
TR | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2020/16] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
MC | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SI | 24.01.2018 | ||
SK | 24.01.2018 | ||
SM | 24.01.2018 | ||
TR | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2019/40] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
MC | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SI | 24.01.2018 | ||
SK | 24.01.2018 | ||
SM | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2019/13] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SI | 24.01.2018 | ||
SK | 24.01.2018 | ||
SM | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/52] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SK | 24.01.2018 | ||
SM | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/51] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
DK | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SK | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/50] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
CZ | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
SK | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/49] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
EE | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
RO | 24.01.2018 | ||
SE | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/47] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
IT | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
SE | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/40] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
SE | 24.01.2018 | ||
BG | 24.04.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/39] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
LT | 24.01.2018 | ||
LV | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
SE | 24.01.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/38] | AT | 24.01.2018 | |
CY | 24.01.2018 | ||
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
LT | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
IS | 24.05.2018 | ||
Former [2018/37] | CY | 24.01.2018 | |
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
LT | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
NO | 24.04.2018 | ||
GR | 25.04.2018 | ||
Former [2018/36] | CY | 24.01.2018 | |
ES | 24.01.2018 | ||
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
LT | 24.01.2018 | ||
NL | 24.01.2018 | ||
PL | 24.01.2018 | ||
NO | 24.04.2018 | ||
Former [2018/35] | CY | 24.01.2018 | |
FI | 24.01.2018 | ||
HR | 24.01.2018 | ||
LT | 24.01.2018 | ||
NL | 24.01.2018 | ||
NO | 24.04.2018 | ||
Former [2018/34] | FI | 24.01.2018 | |
LT | 24.01.2018 | ||
NL | 24.01.2018 | ||
NO | 24.04.2018 | Documents cited: | Search | [XI]WO2006128152 (UNIV JEFFERSON [US], et al) [X] 1-6,11-13 * the whole document * [I] 7,14; | [X]WO2004072117 (PHARMACIA CORP [US], et al) [X] 1-7,11-14 * the whole document *; | [X] - J. GERHART ET AL, "MyoD-positive epiblast cells regulate skeletal muscle differentiation in the embryo", THE JOURNAL OF CELL BIOLOGY, (20060101), vol. 175, no. 2, doi:10.1083/jcb.200605037, ISSN 0021-9525, pages 283 - 292, XP055042620 [X] 3-10,12-15 * the whole document * DOI: http://dx.doi.org/10.1083/jcb.200605037 | [X] - STRONY R ET AL, "NeuroM and MyoD are expressed in separate subpopulations of cells in the pregastrulating epiblast", GENE EXPRESSION PATTERNS, ELSEVIER, AMSTERDAM, NL, vol. 5, no. 3, ISSN 1567-133X, (20050201), pages 387 - 395, (20050201), XP027680294 [X] 3-10,12-15 * the whole document * | [A] - IANG Q ET AL, "EGF-INDUCED CELL MIGRATION IS MEDIATED BY ERK AND PI3K/AKT PATHWAYS IN CULTURED HUMAN LENS EPITHELIAL CELLS", JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, MARY ANN LIEBERT, INC., NEW YORK, NY, US, (20060101), vol. 22, no. 2, doi:10.1089/JOP.2006.22.93, ISSN 1080-7683, pages 93 - 102, XP009072395 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1089/jop.2006.22.93 | [IA] - NAGAMOTO TOSHIYUKI ET AL, "Alpha-smooth muscle actin expression in cultured lens epithelial cells", IOVS, (200004), no. 5, pages 1122 - 1129, XP009164265 [I] 1-8,10-14 * the whole document * [A] 9,15 | [IA] - SCHMITT-GRAFF A ET AL, "APPEARANCE OF ALPHA SMOOTH MUSCLE ACTIN IN HUMAN EYE LENS CELLS OF ANTERIOR CAPSULAR CATARACT AND IN CULTURED BOVINE LENS-FORMING CELLS", DIFFERENTIATION, (1990), vol. 43, no. 2, ISSN 0301-4681, pages 115 - 122, XP002687923 [I] 1-8,10-14 * the whole document * [A] 9,15 DOI: http://dx.doi.org/10.1111/j.1432-0436.1990.tb00437.x | [XI] - J. L. WALKER ET AL, "Activation of Src Kinases Signals Induction of Posterior Capsule Opacification", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, (20070501), vol. 48, no. 5, doi:10.1167/iovs.06-1059, ISSN 0146-0404, pages 2214 - 2223, XP055042502 [X] 1-6,8,11-13 * the whole document * [I] 7,14 DOI: http://dx.doi.org/10.1167/iovs.06-1059 | [XI] - ZHOU J ET AL, "SRC KINASE ACTIVATION INDUCES FORMATION OF LENS OPACITIES THROUGH A PATHWAY", ANNUAL MEETING OF THE ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, XX, XX, (20030508), vol. 2003, XP009072433 [X] 1-6,8,11-13 * the whole document * [I] 7,14 | [XI] - ZHOU J ET AL, "INHIBITION OF SRC FAMILY KINASES BLOCKS FORMATION OF CORTICAL CATARACTS IN CULTURED CHICK EMBRYO LENSES", ANNUAL MEETING OF THE ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, XX, XX, (20020510), vol. 2002, XP009072432 [X] 1-6,8,11-13 * the whole document * [I] 7,14 | [XI] - WORMSTONE I M ET AL, "IDENTIFICATION OF SIGNALLING PATHWAYS INVOLVED IN TGFB2 INDUCED MATRIX CONTRACTION OF HUMAN LENS CELLS", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, (20050501), vol. 46, no. SUPPL. S, ISSN 0146-0404, XP009072393 [X] 1-6,8,11-13 * the whole document * [I] 7,14 | [XI] - WOLFF I M ET AL, "MIGRATION OF LENS EPITHELIAL CELLS ON THE POSTERIOR LENS CAPSULE IS BLOCKED BY INHIBITION OF SRC FAMILY KINASES", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, (20050501), vol. 46, no. SUPPL. S, ISSN 0146-0404, page B421), XP009072394 [X] 1-6,8,11-13 * the whole document * [I] 7,14 | [A] - FRIEDLANDER M, "Fibrosis and diseases of the eye", JOURNAL OF CLINICAL INVESTIGATION, AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, US, (20070301), vol. 117, no. 3, doi:10.1172/JCI31030, ISSN 0021-9738, pages 576 - 586, XP008114654 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1172/JCI31030 | [IP] - GERHART J ET AL, "Noggin producing, MyoD-positive cells are crucial for eye development", DEVELOPMENTAL BIOLOGY, ACADEMIC PRESS, NEW YORK, NY, US, vol. 336, no. 1, ISSN 0012-1606, (20091201), pages 30 - 41, (20090922), XP026802168 [IP] 1-15 * the whole document * | [T] - WALKER JANICE L ET AL, "Unique precursors for the mesenchymal cells involved in injury response and fibrosis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (201008), vol. 107, no. 31, ISSN 0027-8424, pages 13730 - 13735, XP002687924 [T] * the whole document * DOI: http://dx.doi.org/10.1073/pnas.0910382107 | International search | [Y]US6180357 (YOUNG DAVID S F [CA], et al); | [Y] - GERHART ET AL., "MyoD-positive myoblasts are present in mature fetal organs lacking skeletal muscle", THE JOURNAL OF CELL BIOLOGY, (20011029), vol. 155, no. 3, doi:doi:10.1083/jcb.200105139, pages 381 - 391, XP055042480 DOI: http://dx.doi.org/10.1083/jcb.200105139 | [Y] - SRINIVASAN ET AL., "Lens-specific Expression of Transforming Growth Factor B1 in Transgenic Mica Causes Anterior Subcapsular Cataracts", J. CLIN. INVEST., (199802), vol. 101, no. 3, pages 625 - 634 | by applicant | WO2006128152 | WO2004072117 | EP0404097 | WO9311161 | - GERHART et al., J Cell Biol., (20011029), vol. 155, no. 3, pages 381 - 392 | - SRINIVASAN et al., J Clin Invest, (19980201), vol. 101, no. 3, pages 625 - 634 | - GERHART et al., J Cell Biol., (20061023), vol. 175, no. 2, pages 283 - 292 | - STRONY et al., Gene Expression Patterns, (20050201), vol. 5, no. 3, pages 387 - 395 | - NAGAMOTO et al., Invest Ophthalmol Vis Sci., (20000400), vol. 41, no. 5, pages 1122 - 9 | - SCHMITT-GRAFF et al., Differentiation, (19900400), vol. 43, no. 2, pages 115 - 22 | - WALKER et al., Invest Ophthalmol Vis Sci., (20070500), vol. 48, no. 5, pages 2214 - 23 | - WOLFF et al., Investigative Ophthalmology & Visual Science, (20050500), vol. 46, page 2868 | - GERHART et al., Dev Biol., (20091201), vol. 336, no. 1, pages 30 - 41 | - WALKER et al., Proc Natl Acad Sci U S A., (20100803), vol. 107, no. 31, pages 13730 - 5 | - CHAKRAVARTY et al., PNAS, (20080000), vol. 105, pages 8697 - 8702 | - CHO et al., Clin. Cancer Res., (20080000), vol. 14, pages 1310 - 1316 | - Remington's Pharmaceutical Sciences, 18th ed., Mack Publishing Co., (19900000), pages 1435 - 1712 | - TERSKIKH et al., PNAS, (19970000), vol. 94, pages 1663 - 1668 | - HOLLIGER et al., Proc. Natl. Acad. Sci. USA, (19930000), vol. 90, pages 6444 - 6448 | - E.W. MARTIN, Remington's Pharmaceutical Sciences, Mack Publishing Co. | - WALKER et al., Invest. Ophthalmol. Vis. Sci., (20070000), vol. 48, pages 2214 - 23 | - GERHART et al., J. Cell Biol., (20010000), vol. 155, pages 381 - 391 | - GERHART et al., J. Cell Biol., (20040000), vol. 164, pages 739 - 746 | - STRONY et al., Gene Expr. Patterns, (20050000), vol. 5, pages 387 - 395 | - GERHART et al., Biol. Proced. Online, (20040000), vol. 6, pages 149 - 156 | - DECHESNE et al., Mol. Cell. Biol., (19940000), vol. 14, pages 5474 - 5486 | - STRONY et al., Gene Exp. Patterns, (20050000), vol. 5, pages 387 - 395 | - GERHART et al., J. Cell Biol., (20070000), vol. 178, pages 649 - 660 | - GERHART et al., J. Cell Biol., (20060000), vol. 175, pages 283 - 292 | - GERHART et al., Biol. Proc. Online, (20080000), vol. 10, pages 74 - 82 | - RADISKY et al., J. Cell Biochem., (20070000), vol. 101, pages 830 - 9 | - EYDEN, B., J. Cell Mol. Med., (20080000), vol. 12, pages 22 - 37 | - POLYAK et al., Nat. Rev. Cancer, (20090000), vol. 9, pages 265 - 73 | - BAUM et al., Semin. Cell Dev. Biol., (20080000), vol. 19, pages 294 - 308 | - LEE et al., J. Cell Biol., (20060000), vol. 172, pages 973 - 81 | - BELLAIRS, R., Anat Embryol (Berl, (19860000), vol. 174, pages 1 - 14 | - GEORGE-WEINSTEIN et al., Dev. Biol., (19960000), vol. 173, pages 279 - 91 | - GERHART et al., J. Cell. Biol., (20000000), vol. 149, pages 825 - 34 | - GERHART et al., J. Cell. Biol., (20060000), vol. 175, pages 283 - 92 | - GERHART et al., J. Cell. Biol., (20010000), vol. 155, pages 381 - 92 | - STRONY et al., Gene Expr. Patterns, (20050000), vol. 5, pages 387 - 95 | - GERHART et al., J. Cell. Biol., (20040000), vol. 164, pages 739 - 46 | - ASAKURA et al., Dev. Biol., (19950000), vol. 171, pages 386 - 98 | - CHEN et al., Genesis, (20050000), vol. 41, pages 116 - 21 | - GROUNDS et al., Exp. Cell. Res., (19920000), vol. 198, pages 357 - 61 | - GERHART et al., Developmental Biology, (20090000), vol. 336, pages 30 - 41 | - TOMASEK et al., Nat. Rev. Mol. Cell. Biol., (20020000), vol. 3, pages 349 - 63 | - HINZ et al., Am. J. Pathol., (20070000), vol. 170, pages 1807 - 16 | - CATTANEO et al., Nature, (19900000), vol. 347, pages 762 - 5 | - BAI et al., Neuroreport., (20090000), vol. 20, pages 918 - 22 | - HINZ, B., J. Invest. Dermatol., (20070000), vol. 127, pages 526 - 37 | - MAYER et al., J. Cell. Biol., (19970000), vol. 139, pages 1477 - 84 |