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Extract from the Register of European Patents

EP About this file: EP2385115

EP2385115 - EXPRESSION VECTOR FOR PRODUCING PROTEIN DERIVED FROM FOREIGN GENE IN LARGE QUANTITY USING ANIMAL CELLS, AND USE THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  15.07.2016
Database last updated on 02.07.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
National University Corporation Hokkaido University
8, Kita 8-jyo Nishi 5-chome
Kita-ku
Sapporo-shi, Hokkaido 060-0808 / JP
For all designated states
Fuso Pharmaceutical Industries, Ltd.
7-10 Dosho-machi 1-chome Chuo-ku
Osaka-shi, Osaka 541-0045 / JP
[N/P]
Former [2012/39]For all designated states
National University Corporation Hokkaido University
8, Kita 8-jyo Nishi 5-chome Kita-ku
Sapporo-shi, Hokkaido 060-0808 / JP
For all designated states
Fuso Pharmaceutical Industries, Ltd.
7-10 Dosho-machi 1-chome Chuo-ku
Osaka-shi, Osaka 541-0045 / JP
Former [2011/45]For all designated states
National University Corporation Hokkaido University
8, Kita 8-jyo Nishi 5-chome Kita-ku
Sapporo-shi, Hokkaido 060-0808 / JP
For all designated states
Fuso Pharmaceutical Industries, Inc.
7-10, Dosho-Machi 1-chome Chuo-ku Osaka-shi
Osaka 541-0045 / JP
Inventor(s)01 / TAHARA, Hiroshi
c/o WORLD INTEC CO. LTD.
5F Nakatsu Bldg. 1-17-26 Nakatsu
Kita-ku
Osaka / JP
02 / SUZUKI, Yusuke
c/o WORLD INTEC CO. LTD.
5F Nakatsu Bldg. 1-17-26 Nakatsu
Kita-ku
Osaka / JP
03 / YAMAMOTO, Keiichi
c/o FUSO PHARMACEUTICAL INDUSTRIES LTD.
Research and Development Center
2-3-30 Morinomiya
Joto-ku
Osaka-shi Osaka 536-0025 / JP
04 / KITAHARA, Yuzuru
c/o FUSO PHARMACEUTICAL INDUSTRIES LTD.
Research and Development Center
2-3-30 Morinomiya
Joto-ku
Osaka-shi Osaka 536-0025 / JP
05 / SUZUKI, Yasuhiko
c/o National University Corporation,
Hokkaido University, Kita 8-jyo Nishi 5-chome
Kita-ku, Sapporo-shi
Hokkaido 0600808 / JP
 [2012/16]
Former [2012/09]01 / TAHARA, Hiroshi
c/o WORLD INTEC CO. LTD.
5F Nakatsu Bldg. 1-17-26 Nakatsu
Kita-ku
Osaka / JP
02 / SUZUKI, Yusuke
c/o WORLD INTEC CO. LTD.
5F Nakatsu Bldg. 1-17-26 Nakatsu
Kita-ku
Osaka / JP
03 / YAMAMOTO, Keiichi
c/o FUSO PHARMACEUTICAL INDUSTRIES LTD.
Research and Development Center
2-3-30 Morinomiya
Joto-ku
Osaka-shi Osaka 536-0025 / JP
04 / KITAHARA, Yuzuru
c/o FUSO PHARMACEUTICAL INDUSTRIES LTD.
Research and Development Center
2-3-30 Morinomiya
Joto-ku
Osaka-shi Osaka 536-0025 / JP
Former [2011/45]01 / TAHARA, Hiroshi
c/o WORLD INTEC CO. LTD.
13th Floor
PIAS TOWER
3-19-3 Toyosaki, Kita-ku
Osaka-shi Osaka 531-0072 / JP
02 / SUZUKI, Yusuke
c/o WORLD INTEC CO. LTD.
13th Floor
PIAS TOWER
3-19-3 Toyosaki, Kita-ku
Osaka-shi Osaka 531-0072 / JP
03 / YAMAMOTO, Keiichi
c/o FUSO PHARMACEUTICAL INDUSTRIES LTD.
Research and Development Center
2-3-30 Morinomiya
Joto-ku
Osaka-shi Osaka 536-0025 / JP
04 / KITAHARA, Yuzuru
c/o FUSO PHARMACEUTICAL INDUSTRIES LTD.
Research and Development Center
2-3-30 Morinomiya
Joto-ku
Osaka-shi Osaka 536-0025 / JP
Representative(s)Bösl, Raphael Konrad
Patentanwälte Isenbruck Bösl Hörschler PartG mbB
Eastsite One
Seckenheimer Landstraße 4
68163 Mannheim / DE
[N/P]
Former [2015/37]Bösl, Raphael Konrad
Isenbruck Bösl Hörschler LLP
Patentanwälte
Prinzregentenstraße 68
81675 München / DE
Former [2011/45]Bösl, Raphael Konrad
Isenbruck Bösl Hörschler LLP Patentanwälte Prinzregentenstrasse 68
81675 München / DE
Application number, filing date09834881.622.12.2009
[2015/37]
WO2009JP71326
Priority number, dateJP2008032569022.12.2008         Original published format: JP 2008325690
[2011/45]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010074080
Date:01.07.2010
Language:JA
[2010/26]
Type: A1 Application with search report 
No.:EP2385115
Date:09.11.2011
Language:EN
[2011/45]
Type: B1 Patent specification 
No.:EP2385115
Date:09.09.2015
Language:EN
[2015/37]
Search report(s)International search report - published on:JP01.07.2010
(Supplementary) European search report - dispatched on:EP11.07.2012
ClassificationIPC:C12N15/09, C12P21/02, C12Q1/02
[2011/45]
CPC:
C12P21/02 (EP,KR,US); C12N15/85 (EP,KR,US); C12N5/00 (KR);
C12N2830/00 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2015/37]
Extension statesAL07.07.2011
BA07.07.2011
RS07.07.2011
TitleGerman:EXPRESSIONSVEKTOR ZUR HERSTELLUNG VON VON EINEM FREMDGEN ABGELEITETEM PROTEIN IN GROSSER MENGE UNTER VERWENDUNG VON TIERZELLEN UND VERWENDUNG DAVON[2011/45]
English:EXPRESSION VECTOR FOR PRODUCING PROTEIN DERIVED FROM FOREIGN GENE IN LARGE QUANTITY USING ANIMAL CELLS, AND USE THEREOF[2011/45]
French:VECTEUR D'EXPRESSION POUR PRODUIRE UNE PROTÉINE ISSUE D'UN GÈNE ÉTRANGER EN GRANDE QUANTITÉ À L'AIDE DE CELLULES ANIMALES, ET SON UTILISATION[2011/45]
Entry into regional phase07.07.2011Translation filed 
07.07.2011National basic fee paid 
07.07.2011Search fee paid 
07.07.2011Designation fee(s) paid 
07.07.2011Examination fee paid 
Examination procedure07.07.2011Examination requested  [2011/45]
30.01.2013Amendment by applicant (claims and/or description)
20.01.2014Despatch of a communication from the examining division (Time limit: M06)
29.07.2014Reply to a communication from the examining division
24.09.2014Despatch of a communication from the examining division (Time limit: M04)
22.12.2014Reply to a communication from the examining division
10.04.2015Communication of intention to grant the patent
29.07.2015Fee for grant paid
29.07.2015Fee for publishing/printing paid
29.07.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  20.01.2014
Opposition(s)10.06.2016No opposition filed within time limit [2016/33]
Fees paidRenewal fee
23.12.2011Renewal fee patent year 03
19.12.2012Renewal fee patent year 04
27.12.2013Renewal fee patent year 05
22.12.2014Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.12.2009
BG09.09.2015
CY09.09.2015
CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
MC09.09.2015
MK09.09.2015
MT09.09.2015
PL09.09.2015
RO09.09.2015
SI09.09.2015
SK09.09.2015
SM09.09.2015
TR09.09.2015
NO09.12.2015
GR10.12.2015
IE22.12.2015
LU22.12.2015
IS09.01.2016
[2018/30]
Former [2017/38]HU22.12.2009
BG09.09.2015
CY09.09.2015
CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
MC09.09.2015
MT09.09.2015
PL09.09.2015
RO09.09.2015
SI09.09.2015
SK09.09.2015
SM09.09.2015
TR09.09.2015
NO09.12.2015
GR10.12.2015
IE22.12.2015
LU22.12.2015
IS09.01.2016
Former [2016/45]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
MC09.09.2015
PL09.09.2015
RO09.09.2015
SI09.09.2015
SK09.09.2015
NO09.12.2015
GR10.12.2015
IE22.12.2015
LU22.12.2015
IS09.01.2016
Former [2016/36]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
MC09.09.2015
PL09.09.2015
RO09.09.2015
SI09.09.2015
SK09.09.2015
NO09.12.2015
GR10.12.2015
LU22.12.2015
IS09.01.2016
Former [2016/34]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
MC09.09.2015
PL09.09.2015
RO09.09.2015
SK09.09.2015
NO09.12.2015
GR10.12.2015
LU22.12.2015
IS09.01.2016
Former [2016/33]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
MC09.09.2015
PL09.09.2015
RO09.09.2015
SK09.09.2015
NO09.12.2015
GR10.12.2015
IS09.01.2016
Former [2016/25]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
PL09.09.2015
RO09.09.2015
SK09.09.2015
NO09.12.2015
GR10.12.2015
IS09.01.2016
Former [2016/23]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
RO09.09.2015
SK09.09.2015
NO09.12.2015
GR10.12.2015
IS09.01.2016
Former [2016/22]CZ09.09.2015
EE09.09.2015
HR09.09.2015
LT09.09.2015
LV09.09.2015
NO09.12.2015
GR10.12.2015
IS09.01.2016
Former [2016/11]HR09.09.2015
LT09.09.2015
LV09.09.2015
NO09.12.2015
GR10.12.2015
Former [2016/09]LT09.09.2015
LV09.09.2015
NO09.12.2015
GR10.12.2015
Former [2016/08]LT09.09.2015
NO09.12.2015
Former [2016/07]LT09.09.2015
Documents cited:Search[A]WO2006048459  (CHROMAGENICS BV [NL]; OTTE ARIE PIETER [NL]; VAN BLOKLAND HENRICUS JOH) [A] 1-10;
 [A]WO0132901  (CHIRON CORP [US]) [A] 1-10 * the whole document *;
 [A]WO2004024915  (UNIV QUEENSLAND [AU]; FRAZER IAN HECTOR [AU]) [A] 1-10
International search[Y]JP2008518613  (CHROMAGENICS B.V.);
 [Y]US5627033  (RESEARCH & DIAGNOSTICS SYSTEMS, INC.);
 [A]JP2006507842  (BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG.);
 [A]JP2003513635  (KAIRON CORP.);
 [A]JPH08503138  (IDEC PHARMACEUTICALS CORP.);
 [A]JPH06506356  (GENENTECH, INC.);
 [A]WO2006106970  (FUSO PHARMACEUTICAL INDUSTRIES, LTD.);
 [A]JPH06165672  (GENENTECH, INC.);
 [A]JP2006500927  (THE UNIVERSITY OF QUEENSLAND)
 [A]  - VAN BLOCKLAND H.J. ET AL, "A novel, high stringency selection system allows screening of few clones for high protein expression", J. BIOTECHNOL., (20070201), vol. 128, no. 2, pages 237 - 245, XP005829332
 [A]  - ASSELBERGS F.A. ET AL, "Use of the Escherichia coli chromosomal DHFR gene as selection marker in mammalian cells", J. BIOTECHNOL., (19951201), vol. 43, no. 2, pages 133 - 138, XP004036893

DOI:   http://dx.doi.org/10.1016/0168-1656(95)00131-3
 [A]  - GRILLARI J. ET AL, "Analysis of alterations in gene expression after amplification of recombinant genes in CHO cells", J. BIOTECHNOL., (20010427), vol. 87, no. 1, pages 59 - 65, XP004231296

DOI:   http://dx.doi.org/10.1016/S0168-1656(00)00431-4
 [A]  - GANDOR C. ET AL, "Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells", FEBS LETT., (19951227), vol. 377, no. 3, pages 290 - 294, XP026563654

DOI:   http://dx.doi.org/10.1016/0014-5793(95)01328-8
Examination   - ASSELBERGS F A M ET AL, "Use of the Escherichia coli chromosomal DHFR gene as selection marker in mammalian cells", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19951201), vol. 43, no. 2, doi:10.1016/0168-1656(95)00131-3, ISSN 0168-1656, pages 133 - 138, XP004036893

DOI:   http://dx.doi.org/10.1016/0168-1656(95)00131-3
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.