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Extract from the Register of European Patents

EP About this file: EP2289515

EP2289515 - Combinations comprising a diaryl urea and an interferon [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  12.04.2013
Database last updated on 05.10.2024
Most recent event   Tooltip12.04.2013Application deemed to be withdrawnpublished on 15.05.2013  [2013/20]
Applicant(s)For all designated states
Bayer HealthCare LLC
555 White Plains Road
Tarrytown, NY 10591 / US
[2011/09]
Inventor(s)01 / Wilhelm, Scott
29 Masters Lane
Milford, CT 06460 / US
 [2011/09]
Representative(s)Riepe, Hans-Gerd
Pfenning, Meinig & Partner GbR
Patent- und Rechtsanwälte
Theresienhöhe 11a
80339 München / DE
[N/P]
Former [2011/09]Riepe, Hans-Gerd
Pfenning, Meinig & Partner GbR Patent- und Rechtsanwälte Theresienhöhe 13
D-80339 München / DE
Application number, filing date10011899.131.10.2006
[2011/09]
Priority number, dateUS20050731277P31.10.2005         Original published format: US 731277 P
[2011/09]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2289515
Date:02.03.2011
Language:EN
[2011/09]
Type: A3 Search report 
No.:EP2289515
Date:11.04.2012
Language:EN
[2012/15]
Search report(s)(Supplementary) European search report - dispatched on:EP08.03.2012
ClassificationIPC:A61K31/4412, A61K38/21, A61P35/00
[2011/09]
CPC:
A61K38/21 (EP,US); A61K31/44 (EP,US); A61K38/212 (EP,US);
A61P35/00 (EP); A61P43/00 (EP)
C-Set:
A61K31/44, A61K2300/00 (US,EP);
A61K38/212, A61K2300/00 (US,EP);
A61K38/21, A61K2300/00 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/09]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:Kombinationen enthaltend einen Diarylharnstoff und einen Interferon[2011/09]
English:Combinations comprising a diaryl urea and an interferon[2011/09]
French:Combinaison contenant une diaryl urée et un interferon[2011/09]
Examination procedure12.10.2012Application deemed to be withdrawn, date of legal effect  [2013/20]
19.11.2012Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2013/20]
Parent application(s)   TooltipEP06827111.3  / EP1968589
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060827111) is  02.10.2008
Fees paidRenewal fee
30.09.2010Renewal fee patent year 03
30.09.2010Renewal fee patent year 04
30.09.2010Renewal fee patent year 05
11.10.2011Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.10.201207   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]WO2004113274  (BAYER PHARMACEUTICALS CORP [US], et al) [X] 1-9 * p.89: compound 42 * * page 22, lines 12-22 * * page 41, lines 3-12 * [Y] 1-9;
 [IP]WO2006094626  (BAYER HEALTHCARE AG [DE], et al) [IP] 1-9 * claim 1 * * page 3, lines 15-22 * * page 14, line 6 *;
 [IP]WO2006034797  (BAYER HEALTHCARE AG [DE], et al) [IP] 1-9 * claim - * * examples 1,2 * * page 10, line 24 *
 [I]  - "883 POSTER Phase I trial of sorafenib (BAY 43-9006) in combination with interferon alpha-2a in patients with unresectable and/or metastatic renal cell carcinoma and malignant melanoma", EUROPEAN JOURNAL OF CANCER. SUPPLEMENT, PERGAMON, OXFORD, GB, (200510), vol. 3, no. 2, ISSN 1359-6349, page 254, XP005132997 [I] 1-9 * the whole document *
 [I]  - "795 ORAL Phase II trial of sorafenib (BAY 43-9006) in combination with interferon alpha 2b in patients with metastatic renal cell carcinoma", EUROPEAN JOURNAL OF CANCER. SUPPLEMENT, PERGAMON, OXFORD, GB, (200510), vol. 3, no. 2, ISSN 1359-6349, pages 226 - 227, XP005132909 [I] 1-9 * the whole document *
 [Y]  - AHMAD T ET AL, "Kinase inhibition with BAY 43-9006 in renal cell carcinoma", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20040319), vol. 10, no. 18 Pt 2, ISSN 1078-0432, pages 6388S - 6392S, XP002362669 [Y] 1-9 * abstract * * page 6390S, column L, lines 14-23 *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-040028
by applicantWO9404157
 US5023252
 US5011472
 WO0042012
 WO0041698
 WO9800402
 EP0542609
 DE2436108
 US2002042517
 WO02085859
 WO02085857
    - S. M. BERGE ET AL., "Pharmaceutical Salts", J PHARM. SCI., (1977), vol. 66, doi:doi:10.1002/jps.2600660104, pages 1 - 19, XP002675560

DOI:   http://dx.doi.org/10.1002/jps.2600660104
    - WILLIAMS & WILKINS ET AL., PHARMACEUTICAL DOSAGE FORM AND DRUG DELIVERY SYSTEMS, (1995), pages 27 - 29
    - Goodman and Gilman's The Pharmacological Basis of Therapeutics, MCGRAW-HILL, (1996), pages 11 - 13
    - GOODMAN ET AL., Gilman's The Pharmacological Basis of Therapeutics, MCGRAW-HILL, (1996), pages 1225 - 1287
    - Organic Reactions, JOHN WILEY
    - Organic Syntheses, JOHN WILEY
    - Reagents for Organic Synthesis, JOHN WILEY
    - The Total Synthesis of Natural Products, JOHN WILEY
    - The Organic Chemistry of Drug Synthesis, JOHN WILEY
    - Annual Reports in Organic Synthesis, ACADEMIC PRESS
    - Methoden der Organischen Chemie, HOUBEN-WEYL
    - POWELL, M.F. ET AL., "Compendium of Excipients for Parenteral Formulations", PDA JOURNAL OF PHARMACEUTICAL SCIENCE & TECHNOLOGY, (1998), vol. 52, no. 5, pages 238 - 311, XP009119027
    - STRICKLEY, R.G, "Parenteral Formulations of Small Molecule Therapeutics Marketed in the United States (1999)-Part-l", PDA JOURNAL OF PHARMACEUTICAL SCIENCE & TECHNOLOGY, (1999), vol. 53, no. 6, pages 324 - 349
    - NEMA, S. ET AL., "Excipients and Their Use in Injectable Products", PDA JOURNAL OF PHARMACEUTICAL SCIENCE & TECHNOLOGY, (1997), vol. 51, no. 4, pages 166 - 171
    - POWELL, M.F., "Compendium of Excipients for Parenteral Formulations", PDA JOURNAL OF PHARMACEUTICAL SCIENCE & TECHNOLOGY, (1998), vol. 52, no. 5, pages 238 - 311, XP009119027
    - STRICKLEY, R.G, "Parenteral Formulations of Small Molecule Therapeutics Marketed in the United States (1999)-Part-1", PDA JOURNAL OF PHARMACEUTICAL SCIENCE & TECHNOLOGY, (1999), vol. 53, no. 6, pages 324 - 349
    - NEMA, S., "Excipients and Their Use in Injectable Products", PDA JOURNAL OF PHARMACEUTICAL SCIENCE & TECHNOLOGY, (1997), vol. 51, no. 4, pages 166 - 171
    - RIEDL, B. ET AL., "O-Carboxy Aryl Substituted Diphenyl Ureas as raf Kinase Inhibitors", PCT INT. APPL.
    - RIEDL, B. ET AL., "O-Carboxy Aryl Substituted Diphenyl Ureas as p38 Kinase Inhibitors", PCT INT. APPL.
    - BANKSTON ET AL., "A Scaleable Synthesis of BAY 43-9006: A Potent Raf Kinase Inhibitor for the Treatment of Cancer", ORG. PROC. RES. DEV., (2002), vol. 6, no. 6, doi:doi:10.1021/OP020205N, pages 777 - 781, XP002524977

DOI:   http://dx.doi.org/10.1021/OP020205N
    - IBID BIOORG. MED. CHEM., (1995), vol. 3, page 129
    - CHEMICAL ABSTRACTS, Database accession no. 12761B
    - IBID KOGYO KAGAKU ZASSHI, (1967), vol. 70, page 491
 WO2004US15655
 US20010948915
 US20040556062
 US19990605203
 US20030471735
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.