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EP About this file: EP2301961

EP2301961 - SCLEROSTIN EPITOPES [Right-click to bookmark this link]
Former [2011/13]Sclerostin epitopes
[2016/32]
StatusPatent maintained as amended
Status updated on  09.06.2023
Database last updated on 24.04.2024
FormerThe patent has been granted
Status updated on  20.01.2017
FormerGrant of patent is intended
Status updated on  11.01.2017
FormerExamination is in progress
Status updated on  25.11.2016
FormerGrant of patent is intended
Status updated on  22.11.2016
Most recent event   Tooltip10.11.2023Correction of patent specificationpublished on 13.12.2023  [2023/50]
Applicant(s)For all designated states
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, California 91320-1799 / US
[2016/48]
Former [2011/13]For all designated states
UCB Pharma, S.A.
Allée de la Recherche 60
1070 Bruxelles / BE
For all designated states
Amgen, Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1799 / US
Inventor(s)01 / Lu, Hsieng Sen
2758 Rainfield Avenue
Westlake Village California 91362 / US
02 / Paszty, Christopher
1027 Westridge Drive
Ventura California 93003 / US
03 / Robinson, Martyn Kim
Nursery Cottage
Harvey Hill
Woodburn Green Buckinghamshire HP10 0JH / GB
04 / Henry, Alistair James
92 Cowley Road
Uxbridge Middlesex UB 8 2LX / GB
05 / Hoffmann, Kelly Sue
795 Green Valley Drive
Newbury Park California 91320 / US
06 / Latham, John
2409 10th Avenue West
Seattle Washington 98119 / US
07 / Lawson, Alastair
208 Bath Road
Slough Berkshire SL1 3WE / GB
08 / Winkler, David
127 George Street
Arlington Massachusetts 02476-7326 / US
09 / Winters, Aaron George
2501 Pierpont Boulevard
Ventura California 93001 / US
 [2017/08]
Former [2011/13]01 / Lu, Hsieng Sen
2758 Rainfield Avenue
Westlake Village California 91362 / US
02 / Paszty, Christopher
1027 Westridge Drive
Ventura California 93003 / US
03 / Robinson, Martyn Kim
Nursery Cottage Harvey Hill
Woodburn Green Buckinghamshire HP10 0JH / GB
04 / Henry, Alistair James
92 Cowley Road
Uxbridge Middlesex UB 8 2LX / GB
05 / Hoffmann, Kelly Sue
795 Green Valley Drive
Newbury Park California 91320 / US
06 / Latham, John
2409 10th Avenue West
Seattle Washington 98119 / US
07 / Lawson, Alastair
208 Bath Road
Slough Berkshire SL1 3WE / GB
08 / Winkler, David
127 George Street
Arlington Massachusetts 02476-7326 / US
09 / Winters, Aaron George
2501 Pierpont Boulevard
Ventura California 93001 / US
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[2023/28]
Former [2017/08]Campbell, Patrick John Henry
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2011/13]Campbell, Patrick John Henry
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Application number, filing date10014373.428.04.2006
[2011/13]
Priority number, dateUS20050677583P03.05.2005         Original published format: US 677583 P
US20060776847P24.02.2006         Original published format: US 776847 P
US20060782244P13.03.2006         Original published format: US 782244 P
US20060792645P17.04.2006         Original published format: US 792645 P
US2006041054025.04.2006         Original published format: US 410540
[2011/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2301961
Date:30.03.2011
Language:EN
[2011/13]
Type: B1 Patent specification 
No.:EP2301961
Date:22.02.2017
Language:EN
[2017/08]
Type: B2 New European patent specification 
No.:EP2301961
Date:12.07.2023
Language:EN
[2023/28]
Type: B9 Corrected patent specification 
No.:EP2301961
Date:13.12.2023
[2023/50]
Search report(s)(Supplementary) European search report - dispatched on:EP24.02.2011
ClassificationIPC:A61K39/00, C07K16/18, C07K16/22, C12N15/63, C07K14/51
[2016/31]
CPC:
C07K14/51 (EP,US); C07K16/18 (US); A61P15/12 (EP);
A61P19/00 (EP); A61P19/08 (EP); A61P19/10 (EP);
A61P43/00 (EP); C07K16/22 (EP,US); C12N15/63 (EP,US);
A61K2039/505 (EP,US); C07K2317/24 (EP,US); C07K2317/76 (EP,US);
C07K2317/92 (EP,US) (-)
Former IPC [2011/13]C07K14/51, A61K38/10, A61K38/17
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/08]
Former [2011/13]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL14.09.2011
BA14.09.2011
HR14.09.2011
MK14.09.2011
YU14.09.2011
TitleGerman:SCLEROSTIN EPITOPE[2016/31]
English:SCLEROSTIN EPITOPES[2016/32]
French:EPITOPES DE LA SCLEROSTIN[2023/28]
Former [2011/13]Sclerostin Epitope
Former [2011/13]Sclerostin epitopes
Former [2011/13]Epitopes de la sclerostin
Examination procedure14.09.2011Examination requested  [2011/43]
07.11.2011Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
17.01.2012Amendment by applicant (claims and/or description)
05.08.2014Despatch of a communication from the examining division (Time limit: M06)
16.02.2015Reply to a communication from the examining division
15.07.2015Despatch of a communication from the examining division (Time limit: M06)
15.01.2016Reply to a communication from the examining division
20.07.2016Communication of intention to grant the patent
18.11.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
18.11.2016Fee for grant paid
18.11.2016Fee for publishing/printing paid
11.01.2017Information about intention to grant a patent
11.01.2017Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP06751835.7  / EP1891100
EP10006930.1  / EP2251351
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060751835) is  30.10.2008
Opposition(s)Opponent(s)01  22.11.2017  28.11.2017  ADMISSIBLE
James Poole Limited
One Southampton Row
London WC1B 5HA / GB
Opponent's representative
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
 [2021/37]
Former [2018/01]
Opponent(s)01  22.11.2017  28.11.2017  ADMISSIBLE
James Poole Limited
One Southampton Row
London WC1B 5HA / GB
Opponent's representative
Marshall, Cameron John
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
11.12.2017Invitation to proprietor to file observations on the notice of opposition
30.04.2018Reply of patent proprietor to notice(s) of opposition
16.01.2019Cancellation of oral proceeding that was planned for 12.06.2019
01.03.2019Cancellation of oral proceeding that was planned for 07.11.2019
12.06.2019Date of oral proceedings
07.11.2019Date of oral proceedings
13.11.2019Date of oral proceedings
06.12.2019Despatch of interlocutory decision in opposition
06.12.2019Despatch of minutes of oral proceedings
03.02.2023Legal effect of interlocutory decision in opposition
22.02.2023Despatch of communication that the patent will be maintained as amended
31.05.2023Fee for printing new specification paid
Appeal following opposition14.02.2020Appeal received No.  T0398/20
01.05.2020Statement of grounds filed
03.02.2023Result of appeal procedure: appeal of the opponent withdrawn
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
17.01.2012Request for further processing filed
17.01.2012Full payment received (date of receipt of payment)
Request granted
25.01.2012Decision despatched
Fees paidRenewal fee
03.02.2011Renewal fee patent year 03
03.02.2011Renewal fee patent year 04
03.02.2011Renewal fee patent year 05
12.04.2011Renewal fee patent year 06
28.03.2012Renewal fee patent year 07
12.04.2013Renewal fee patent year 08
25.03.2014Renewal fee patent year 09
10.04.2015Renewal fee patent year 10
11.04.2016Renewal fee patent year 11
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]WO2005003158  (CELLTECH R & D INC [US], et al) [X] 15-20 * sequences 74, 76, 98 * * page 41, line 5 - line 7 * * page 46, line 22 - line 25 * [Y] 1-20;
 [XY]WO2005014650  (CELLTECH R & D INC [US], et al) [X] 15-20 * sequences 29, 31, 53 * * page 6, line 23 - line 28 * [Y] 1-20;
 [Y]  - VITER S S ET AL, "Analysis of antigenic structure of Potato Virus M Ukrainian strains", BIOPOLIMERY I KLETKA, NAUKOVA DUMKA, KIEV, UK, (20000701), vol. 16, no. 4, ISSN 0233-7657, pages 312 - 319, XP009144175 [Y] 1 * page 315, column 1, paragraph 2 *
 [A]  - AVSIAN-KRETCHMER ORNA ET AL, "Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists.", MOLECULAR ENDOCRINOLOGY, (200401), vol. 18, no. 1, ISSN 0888-8809, pages 1 - 12, XP002400896 [A] 1-20 * the whole document *
by applicantUS4179337
 US4301144
 US4331647
 US4411993
 US4464456
 US4496689
 US4543439
 USRE32011E
 US4640835
 US4670417
 US4791192
 US4902614
 WO9202551
 US5145684
 US5223409
 US5399363
 US5466468
 US5543158
 US5552157
 US5565213
 US5567434
 US5627052
 US5641515
 US5698426
 US5738868
 US5795587
 US5877397
 US6133426
 US6395511
 US2004009535
 US6703199
 US2004146888
 US6803453
 US2005106683
 US2005238646
    - RIGGS, WEST J. MED., (1991), vol. 154, pages 63 - 77
    - BRUNKOW ET AL., AM. J. HUM. GENET., (2001), vol. 68, pages 577 - 589
    - BALEMANS ET AL., HUM. MOL. GENET., (2001), vol. 10, pages 537 - 543
    - HOLLINGER; HUDSON, NATURE BIOTECHNOLOGY, (2005), vol. 23, no. 9, pages 1126 - 1136
    - NISONOFF ET AL., ARCH. BIOCHEM. BIOPHYS., (1960), vol. 89, page 230
    - PORTER, BIOCHEM. J., (1959), vol. 73, page 119
    - EDELMAN ET AL., Methods in Enzymology, ACADEMIC PRESS, (1967), vol. 1, page 422
    - ANDREWS, S.M.; TITUS, J.A. ET AL., Current Protocols in Immunology, JOHN WILEY & SONS, (2003), pages 2.8.1 - 2.8.10,2
    - LARRICK ET AL., METHODS: A COMPANION TO METHODS IN ENZYMOLOGY, (1991), vol. 2, page 106
    - "Genetic Manipulation of Monoclonal Antibodies", COURTENAY-LUCK ET AL., Monoclonal Antibodies: Production, Engineering and Clinical Application, CAMBRIDGE UNIVERSITY PRESS, (1995), page 166
    - "Genetic Manipulation and Expression of Antibodies", WARD ET AL., Monoclonal Antibodies: Principles and Applications, WILEY-LISS, INC., (1995), page 137
    - MOULT J., CURR. OP. IN BIOTECH., (1996), vol. 7, no. 4, pages 422 - 427
    - CHOU ET AL., BIOCHEMISTRY, (1974), vol. 13, no. 2, pages 222 - 245
    - CHOU ET AL., BIOCHEMISTRY, (1974), vol. 113, no. 2, pages 211 - 222
    - CHOU ET AL., ADV. ENZYMOL. RELAT AREAS MOL. BIOL., (1978), vol. 47, pages 45 - 148
    - CHOU ET AL., ANN. REV. BIOCHEM., vol. 47, pages 251 - 276
    - CHOU ET AL., BIOPHYS. J., (1979), vol. 26, pages 367 - 384
    - HOLM ET AL., NUCL. ACID. RES., (1999), vol. 27, no. 1, pages 244 - 247
    - BRENNER ET AL., CURR. OP. STRUCT. BIOL., (1997), vol. 7, no. 3, pages 369 - 376
    - JONES, D., CURR. OPIN. STRUCT. BIOL., (1997), vol. 7, no. 3, pages 377 - 87
    - SIPPL ET AL., STRUCTURE, (1996), vol. 4, no. 1, pages 15 - 19
    - BOWIE ET AL., SCIENCE, (1991), vol. 253, pages 164 - 170
    - GRIBSKOV ET AL., METH. ENZYM., (1990), vol. 183, pages 146 - 159
    - GRIBSKOV ET AL., PROC. NAT. ACAD. SCI., (1987), vol. 84, no. 13, pages 4355 - 4358
    - THORNTON ET AL., NATURE, (1991), vol. 354, page 105
    - NYGREN; UHLEN, CURRENT OPINION IN STRUCTURAL BIOLOGY, (1997), vol. 7, pages 463 - 469
    - ZHANG, W. ET AL., MOLECULAR IMMUNOLOGY., (2005), vol. 42, no. 12, pages 1445 - 1451
    - HWANG W. ET AL., METHODS, (2005), vol. 36, no. 1, pages 35 - 42
    - DAU'ACQUA WF ET AL., METHODS, (2005), vol. 36, no. 1, pages 43 - 60
    - CLARK, M., IMMUNOLOGY TODAY, (2000), vol. 21, no. 8, pages 397 - 402
    - PLUCKTHUN ET AL., METHODS ENZYMOL., (1989), vol. 178, pages 497 - 515
    - SANGER ET AL., PNAS, (1977), vol. 74, page 5463
    - KRAMER ET AL., NUCLEIC ACIDS RES., (1984), vol. 12, page 9441
    - KUNKEL, PROC. NATL. ACAD. SCI. USA, (1985), vol. 82, pages 488 - 92
    - KUNKEL ET AL., METHODS IN ENZYMOL., (1987), vol. 154, pages 367 - 82
    - YANG ET AL., J. MOL. BIOL., (1995), vol. 254, pages 392 - 403
    - MARKS ET AL., BIO/TECHNOLOGY, (1992), vol. 10, pages 779 - 783
    - LOW ET AL., J. MOL. BIOL., (1996), vol. 250, pages 350 - 368
    - PATTEN ET AL., CURR. OPIN. BIOTECLMOL., (1997), vol. 8, pages 724 - 733
    - THOMPSON ET AL., J. MOL. BIOL., (1996), vol. 256, pages 7 - 88
    - CRAMERI ET AL., NATURE, (1998), vol. 391, pages 288 - 291
    - VAUGHAN ET AL., NATURE BIOTECHNOLOGY, (1998), vol. 16, pages 535 - 539
    - KOHLER ET AL., NATURE, (1975), vol. 256, page 495
    - COLIGAN ET AL., Current Protocols in Immunology, JOHN WILEY & SONS, (1991), vol. 1
    - "Production of monoclonal antibodies against proteins expressed in E. coli", PICKSLEY ET AL., DNA Cloning 2: Expression Systems, OXFORD UNIVERSITY PRESS, (1995), page 93
    - "Purification of Immunoglobulin G (IgG)", BAINES ET AL., Methods in Molecular Biology, HUMANA PRESS, INC., (1992), vol. 10, pages 79 - 104
    - GREEN ET AL., NATURE GENET., (1994), vol. 7, page 13
    - LONBERG, NATURE, (1994), vol. 368, page 856
    - TAYLOR, INT. IMMUN., (1994), vol. 6, page 579
    - BRUGGEMANN, CURR. OPIN. BIOTECHNOL., (1997), vol. 8, pages 455 - 58
    - JAKOBOVITS ET AL., ANN. N. Y. ACAD SCI., (1995), vol. 764, pages 525 - 35
    - BRUGGEMANN ET AL., CURR. OPIN. BIOTECHNOL., (1997), vol. 8, pages 455 - 58
    - GLASKY ET AL., HYBRIDOMA, (1989), vol. 8, pages 377 - 89
    - BOERNER ET AL., J LMMUNOL., (1991), vol. 147, pages 86 - 95
    - BABCOOK ET AL., PROC. NATL. ACAD. SCI. USA, (1996), vol. 93, pages 7843 - 48
    - WINTER ET AL., ANNU. REV: IMMUNOL., (1994), vol. 12, pages 433 - 55
    - BURTON ET AL., ADV. IMMUNOL., (1994), vol. 57, pages 191 - 280
    - HUSE ET AL., SCIENCE, (1989), vol. 246, pages 1275 - 81
    - SASTRY ET AL., PROC. NATL. ACAD. SCI. USA, (1989), vol. 86, pages 5728 - 32
    - ALTING-MEES ET AL., STRATEGIES IN MOLECULAR BIOLOGY, (1990), vol. 3, pages 1 - 9
    - KANG ET AL., PROC. NATL. ACAD. SCI. USA, (1991), vol. 88, pages 4363 - 66
    - HOOGENBOOM ET AL., J. MOLEC. BIOL., (1992), vol. 227, pages 381 - 388
    - SCHLEBUSCH ET AL., HYBRIDOMA, (1997), vol. 16, pages 47 - 52
    - BIRD ET AL., SCIENCE, (1988), vol. 242, pages 423 - 426
    - HARRIS, RJ., JOURNAL OF CHROMATOGRAPHY, (1995), vol. 705, pages 129 - 134
    - ANGAL SET, MOL IMMUNOL, (1993), vol. 30, no. 1, pages 105 - 108
    - SCATCHARD, ANN. N.Y. ACAD. SCI., (1949), vol. 51, pages 660 - 672
    - WOLFF ET AL., CANCER RES., (1993), vol. 53, pages 2560 - 65
    - SUDO H; KODAMA H-A; AMAGAI Y; YAMAMOTO S; KASAI S, "vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria", J. CELL BIOL., (1983), vol. 96, doi:doi:10.1083/jcb.96.1.191, pages 191 - 198, XP002000687

DOI:   http://dx.doi.org/10.1083/jcb.96.1.191
    - SMITH E; REDMAN R; LOGG C; COETZEE G; KASAHARA N; FRENKEL B, "Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle", J. BIOL. CHEM., (2000), vol. 275, pages 19992 - 20001
    - Remington's Pharmaceutical Sciences, pages 1035 - 1038,157
    - LASIC, TRENDS BIOTECHNOL., (1998), vol. 16, no. 7, pages 307 - 21
    - TAKAKURA, NIPPON RINSHO, (1998), vol. 56, no. 3, pages 691 - 95
    - CHANDRAN ET AL., INDIAN J. EXP. BIOL., (1997), vol. 35, no. 8, pages 801 - 09
    - MARGALIT, CRIT. REV. THER. DRUG CARRIER SYST., (1995), vol. 12, no. 2-3, pages 233 - 61
    - QUINTANAR-GUERRERO ET AL., DRUG DEV. IND PHARM., (1998), vol. 24, no. 12, pages 1113 - 28
    - COUVREUR ET AL., CRIT. REV. THER. DRUG CARRIER SYST., (1988), vol. 5, no. 1, pages 1 - 20
    - ZUR MUHLEN ET AL., EUR. J. PHARM. BIOPHARM., (1998), vol. 45, no. 2, pages 149 - 55
    - ZAMBAUX ET AL., J CONTROLLED RELEASE, (1998), vol. 50, no. 1-3, pages 31 - 40
    - COMIER, CURR. OPIN. IN RHEU., (1995), vol. 7, page 243
    - GUINNESS-HEY, METAB. BONE DIS. RELAT. RES., (1984), vol. 5, pages 177 - 181
    - KALU, D.N., "The ovariectomized rat model ofpostmenopausal bone loss", BONE AND MINERAL, (1991), vol. 15, pages 175 - 192
    - FROST, H.M.; JEE, W.S.S., "Qn the rat'model of human osteopenias and osteoporosis", BONE AND MINERAL, (1992), vol. 18, doi:doi:10.1016/0169-6009(92)90809-R, pages 227 - 236, XP023072088

DOI:   http://dx.doi.org/10.1016/0169-6009(92)90809-R
    - JEE, W.S.S.; YAO, W., "Overview: animal models of osteopenia and osteoporosis", J MUSCULOSKEL. NEURON. INTERACT., (2001), vol. 1, pages 193 - 207
    - SUDO H ET AL., "vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria", J. CELL BIOL., vol. 96, doi:doi:10.1083/jcb.96.1.191, pages 191 - 198, XP002000687

DOI:   http://dx.doi.org/10.1083/jcb.96.1.191
    - SMITH E; REDMAN R; LOGG C; COETZEE Q; KASAHARA N; FRENKEL B, "Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle", J BIOL CHEM, (2000), vol. 275, pages 19992 - 20001
    - SUDO H; KODAMA H-A; AMAGAI Y; YAMAMOTO S; KASAI S, "vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria", J CELL BIOL, (1983), vol. 96, doi:doi:10.1083/jcb.96.1.191, pages 191 - 198, XP002000687

DOI:   http://dx.doi.org/10.1083/jcb.96.1.191
    - BYRNE, F. R. ET AL., GUT, (2005), vol. 54, pages 78 - 86
 US20030478977
 US20040868497
OppositionWO0032773
 WO2005003158
 WO2005014650
    - VITER et al., "Analysis of antigenic structure of Potato Virus M Ukrainian strains", Biopolymers & Cell, (20000000), vol. 16, no. 4, pages 312 - 319, XP009144175
    - AVSIAN-KRETCHMER et al., "Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists", Mol. Endocrinol., (20040000), vol. 18, no. 1, pages 1 - 12, XP002400896
    - HUGO et al., "Functional aspects of co-variant surf ace charges in an antibody fragment", Prot. Sci., (20020000), vol. 11, pages 2697 - 2705, XP055261739
    - Warmington K. et al., "Sclerostin Antagonism in Adult Rodents, via Monoclonal Antibody Mediated Blockade, Increases Bone Mineral Density and Implicates Sclerostin as a Key Regulator of Bone Mass During Adulthood", Oasis, Online Abstract Submission and Invitation System, (20040000), XP009072609

DOI:   http://dx.doi.org/10.1359/JBMR.0301211
    - Declaration of Chris Paszty of 14 June 2012
    - Reverberi and Reverberi, 2007, Blood Transfus., 5, 227-240
    - Lee and Kerns (1999) LS/MS Applications in Drug Development, Mass Spectrometry Reviews 18, 187-279
    - Robb et al. (2000), Anal. Chem., 72. 3653-3659
    - Arpino et al. (1989) Mass Spectrometry Reviews, 8, 35-55
    - Ardrey (2003), Liquid Chromatography - Mass Spectrometry: An Introduction. John Wiley & Sons, Ltd
    - Niessen (2006). Liquid Chromatography - Mass Spectrometry, Third Edition. Boca Raton: CRC Taylor & Francis
    - Declaration of Prof. Schwartz
    - New continuous chemistry systems offers the widest range of reactions
    - Syrris Releae. New continuous chemistry system offers the widest range of reactions
    - A. Raines "The Calvin Cycle Revisited" - 18.04.2022
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.