blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2199410

EP2199410 - Plasminogen activator inhibitor-1 (PAI-1) Polymorphism useful as indicators of patient outcome [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  18.03.2011
Database last updated on 21.05.2024
Most recent event   Tooltip18.03.2011Withdrawal of applicationpublished on 20.04.2011  [2011/16]
Applicant(s)For all designated states
UNIVERSITY OF BRITISH COLUMBIA
University Industry Liaison Office 103-6190 Agronomy Road
Vancouver, BC V6T 1Z3 / CA
[2010/26]
Former [2010/25]For all designated states
The University Of British Columbia
University - Industry Liaison Office 103 - 6190 Agronomy Road
Vancover, BC V6T 1Z3 / CA
Inventor(s)01 / Russell, James A.
1963 West 35th Avenue
Vancouver British Columbia V6M 1H8 / CA
02 / Walley, Keith R.
4172 Coventry Way
North Vancouver British Columbia V7N 4M9 / CA
 [2010/25]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[N/P]
Former [2010/25]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date10154345.219.03.2004
[2010/25]
Priority number, dateUS20030455550P19.03.2003         Original published format: US 455550 P
[2010/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2199410
Date:23.06.2010
Language:EN
[2010/25]
Search report(s)(Supplementary) European search report - dispatched on:EP03.05.2010
ClassificationIPC:C12Q1/68
[2010/25]
CPC:
C12Q1/6883 (EP,US); C12Q2600/156 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/25]
TitleGerman:Polymorphismus des Plasminogen-Aktivator-Inhibitor-1 (PAI-1) zur Krankheitsprognose[2010/25]
English:Plasminogen activator inhibitor-1 (PAI-1) Polymorphism useful as indicators of patient outcome[2010/25]
French:Polymorphisme du plasminogen activator inhibitor-1 (PAI-1) pour le pronostic de maladie[2010/25]
Examination procedure23.02.2010Examination requested  [2010/25]
01.02.2011Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
10.03.2011Application withdrawn by applicant  [2011/16]
Parent application(s)   TooltipEP04721788.0  / EP1618208
Fees paidRenewal fee
23.02.2010Renewal fee patent year 03
23.02.2010Renewal fee patent year 04
23.02.2010Renewal fee patent year 05
23.02.2010Renewal fee patent year 06
23.02.2010Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]WO9853098  (BIOTECHNOLOG FORSCHUNG GMBH [DE], et al) [X] 1-3,6 * claims 12,13 * * page 2, paragraph 2 * * abstract * [Y] 4,5;
 [A]US2002086838  (OH CHAD K [US], et al) [A] 1-6* the whole document *;
 [Y]  - "http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?searchType=adhoc_search&type=rs&rs=rs7242", dbSNP, NCBI, (19990910), Database accession no. rs7242, URL: NCBI, XP002578065 [Y] 4,5 * the whole document *
 [A]  - BENZA, "Association of a Gene Polymorphism for PAI-1 with Primary Pulmonary Hypertension", CARDIOPULMONARY CRITICAL CARE NEWSLETTER, URL: http://www.americanheart.org/downloadable/heart/1017868019324CPCCSprng02.pdf, (20020301), XP002287063 [A] 1-6 * page 9, column 3 *
 [A]  - HERMANS PETER W M ET AL, "4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease", LANCET (NORTH AMERICAN EDITION), (19990814), vol. 354, no. 9178, ISSN 0099-5355, pages 556 - 560, XP002287064 [A] 1-6 * page 556, column 1 *

DOI:   http://dx.doi.org/10.1016/S0140-6736(99)02220-5
 [A]  - GAILLARD M-C ET AL, "Identification of DNA polymorphisms associated with the V type alpha1-antitrypsin gene", BIOCHIMICA ET BIOPHYSICA ACTA . GENE STRUCTURE AND EXPRESSION, ELSEVIER, AMSTERDAM, NL, (19990216), vol. 1444, no. 2, ISSN 0167-4781, pages 166 - 170, XP004275307 [A] 1-6 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0167-4781(98)00271-1
 [A]  - DAWSON SALLY J ET AL, "The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells", JOURNAL OF BIOLOGICAL CHEMISTRY, (1993), vol. 268, no. 15, ISSN 0021-9258, pages 10739 - 10745, XP002287069 [A] 1-6 * the whole document *
by applicantUS5128247
 US5130423
 US5674743
 US5945515
 US5989431
 US6025136
 US6270961
 WO0181631
    - SUFFREDINI AF ET AL., NEW ENGLAND JOURNAL OF MEDICINE, (1989), vol. 320, no. 18, pages 1165 - 72
    - HESSELVIK JF ET AL., CRITICAL CARE MEDICINE, (1989), vol. 17, no. 8, pages 724 - 33
    - PHILIPPE J ET AL., THROMBOSIS & HAEMOSTASIS, (1991), vol. 65, no. 3, pages 291 - 5
    - LORENTE JA, CHEST, (1993), vol. 103, no. 5, pages 1536 - 42
    - FOURRIER F ET AL., CHEST, (1992), vol. 101, no. 3, pages 816 - 23
    - BINDER BR ET AL., NEWS IN PHYSIOLOGICAL SCIENCES, (2000), vol. 17, pages 56 - 61
    - MESTERS RM ET AL., THROMBOSIS & HAEMOSTASIS., (1996), vol. 75, no. 6, pages 902 - 7
    - PRALONG G, THROMBOSIS & HAEMOSTASIS., (1989), vol. 61, no. 3, pages 459 - 62
    - HERMANS PW ET AL., LANCET., (1999), vol. 354, no. 9178, pages 556 - 60
    - MENGES T ET AL., LANCET, (2001), vol. 357, no. 9262, pages 1096 - 7
    - DAWSON ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, (1993), vol. 268, no. 15, pages 10739 - 45
    - DAWSON SJ ET AL., ARTERIOSCLEROSIS & THROMBOSIS, (1991), vol. 11, no. 1, pages 183 - 90
    - SEGUI R ET AL., BRITISH JOURNAL OF HAEMATOLOGY, (2000), vol. 111, no. 1, pages 122 - 8
    - HINDORFF LA ET AL., JOURNAL OF CARDIOVASCULAR RISK, (2002), vol. 9, no. 2, pages 31 - 7
    - BOEKHOLDT SM ET AL., CIRCULATION, (2001), vol. 104, no. 25, pages 3063 - 8
    - ERIKSSON P ET AL., PNAS, (1995), vol. 92, no. 6, pages 1851 - 5
    - ORTLEPPG JR ET AL., CLINICAL CARDIOLOGY, (2001), vol. 24, no. 9, pages 585 - 91
    - ANVARI A ET AL., THROMBOSIS RESEARCH, (2001), vol. 103, no. 2, pages 103 - 7
    - MIKKELSSON J ET AL., THROMBOSIS & HAEMOSTASIS, (2000), vol. 84, no. 1, pages 78 - 82
    - WESTENDORP RG ET AL., LANCET, (1999), vol. 354, no. 9178, pages 561 - 3
    - ENDLER G ET AL., BRITISH JOURNAL OF HAEMATOLOGY, (2000), vol. 110, no. 2, pages 469 - 71
    - GARDEMANN A ET AL., THROMBOSIS & HAEMOSTASIS, (1999), vol. 82, no. 3, pages 1121 - 6
    - HOOPER WC ET AL., THROMBOSIS RESEARCH, (2000), vol. 99, no. 3, pages 223 - 30
    - JONES K ET AL., EUROPEAN JOURNAL OF VASCULAR & ENDOVASCULAR SURGERY, (2002), vol. 23, no. 5, pages 421 - 5
    - HARALAMBOUS E. ET AL., CRIT CARE MED, (2003), vol. 31, no. 12, pages 2788 - 93
    - ROEST M ET AL., CIRCULATION, (2000), vol. 101, no. 1, pages 67 - 70
    - RUSSELL JA, CRIT CARE MED., (2003), vol. 31, no. 4, pages S243 - S247
    - CRITICAL CARE MEDICINE, (1992), vol. 20, no. 6, pages 864 - 74
    - VINCENT ET AL., "Scoring systems for assessing organ dysfunction and survival", CRITICAL CARE CLINICS, (2000), vol. 16, pages 353 - 366
    - KNAUS WA ET AL., CHEST, (1991), vol. 100, no. 6, pages 1619 - 36
    - SAMBROOK, J. ET AL., Molecular Cloning, COLD SPRING HARBOR LABORATORY PRESS, (1989), vol. 2, pages 9.14 - 9.23
    - AUSUBEL, FM. ET AL., Current Protocols in Molecular Biology, JOHN WILEY & SONS, INC., (1994), vol. 1, pages 2.2.1 - 2.4.5
    - ANALECTS, PHARMACIA BIOTECH, (1994), vol. 22, no. 4
    - BOTWELL DDL, ANAL. BIOCHEM., (1987), vol. 162, pages 463 - 465
    - MAXAM AM.; GILBERT W., PROC. NATL. ACAD. SCI. USA, (1977), vol. 74, no. 4, pages 560 - 564
    - SANGER ET AL., PROC. NATL. ACAD. SCI. USA, (1977), vol. 74, no. 12, pages 5463 - 5467
    - ZIMMERN D.; KAESBERG P., PROC. NATL. ACAD. SCI. USA, (1978), vol. 75, no. 9, pages 4257 - 4261
    - MILLS DR.; KRAMER FR, PROC. NATL. ACAD. SCI. USA, (1979), vol. 76, no. 5, pages 2232 - 2235
    - PEATTIE DA, PROC. NATL. ACAD. SCI. USA, (1979), vol. 76, no. 4, pages 1760 - 1764
    - DONIS-KELLER ET AL., NUCL, ACIDS RES., (1977), vol. 4, pages 2527 - 2538
    - SIMONCSITS A. ET AL., NATURE, (1977), vol. 269, no. 5631, pages 833 - 836
    - AXELROD VD. ET AL., NUCL. ACIDS RES., (1978), vol. 5, no. 10, pages 3549 - 3563
    - KRAMER FR.; MILLS DR., PROC. NATL. ACAD. SCI. USA, (1978), vol. 75, no. 11, pages 5334 - 5338
    - FREEMAN BD. ET AL., J MOL DIAGNOSTICS, (2002), vol. 4, no. 4, pages 209 - 215
    - VILLAHERMOSA ML., J HUM VIROL, (2001), vol. 4, no. 5, pages 238 - 48
    - ROMPPANEN EL., SCAND J CLIN LAB INVEST, (2001), vol. 61, no. 2, pages 123 - 9
    - IANNONE MA ET AL., CYTOMETRY, (2000), vol. 39, no. 2, pages 131 - 40
    - QI X. ET AL., NUCLEIC ACIDS RES, (2001), vol. 29, no. 22, page E116
    - AYDIN A. ET AL., BIOTECHNIQUES, (2001), vol. 4, pages 920 - 2,924,926-8
    - PATOLSKY F ET AL., NAT BIOTECH., (2001), vol. 19, no. 3, pages 253 - 257
    - HAWKINS JR. ET AL., HUM MUTAT, (2002), vol. 19, no. 5, pages 543 - 553
    - ANONYMOUS, CRITICAL CARE MEDECINE, (1992), vol. 20, no. 6, pages 864 - 74
    - KNAUS WA· ET AL., CHEST, (1991), vol. 100, no. 6, pages 1619 - 36
    - RUSSELL JA ET AL., CRITICAL CARE MEDICINE, (2000), vol. 28, no. 10, pages 3405 - 11
    - ANONYMOUS, NEW ENGLAND JOURNAL OF MEDICINE, (2000), vol. 342, no. 18, pages 1301 - 8
    - BERNARD GR ET AL., NEW ENGLAND JOURNAL OF MEDICINE, (1997), vol. 336, no. 13, pages 912 - 8
    - ANONYMOUS, CRITICAL CARE MEDICINE, (1992), vol. 20, no. 6, pages 864 - 74
    - KOKORIS M ET AL., MOLECULAR DIAGNOSIS, (2000), vol. 5, no. 4, pages 329 - 40
    - PATIL ET AL., SCIENCE, (2001), vol. 294, no. 5547, pages 1669 - 70
    - STEPHENS M; DONNELLY P, AIN J HUMAN GENET., (2003), vol. 73, no. 6, pages 1162 - 1169
    - CARDON LR; BELL JI, NATURE REVIEWS GENETICS, (2001), vol. 2, pages 91 - 9
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.