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Extract from the Register of European Patents

EP About this file: EP2275425

EP2275425 - Novel crystalline forms of temozolomide [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.01.2012
Database last updated on 07.10.2024
Most recent event   Tooltip27.01.2012Application deemed to be withdrawnpublished on 29.02.2012  [2012/09]
Applicant(s)For all designated states
CHEMAGIS LTD.
29 Lehi Street
51200 Bnei-Brak / IL
[2011/03]
Inventor(s)01 / Adin, Itai
11 Nathan Yelin-Mor Street
84684 Beer Sheva / IL
02 / Iustain, Carmen
5 Burla Street
84000 Beer Sheva / IL
 [2011/03]
Representative(s)Albrecht, Thomas
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[N/P]
Former [2011/03]Albrecht, Thomas
Kraus & Weisert Patent- und Rechtsanwälte Thomas-Wimmer-Ring 15
80539 München / DE
Application number, filing date10177879.330.12.2004
[2011/03]
Priority number, dateUS20030532944P30.12.2003         Original published format: US 532944 P
[2011/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2275425
Date:19.01.2011
Language:EN
[2011/03]
Search report(s)(Supplementary) European search report - dispatched on:EP01.12.2010
ClassificationIPC:C07D487/04, A61K31/4188, A61P35/00
[2011/03]
CPC:
C07D487/04 (EP,US); A61P35/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/03]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
LVNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:Neue kristalline Formen von Temozolomid[2011/03]
English:Novel crystalline forms of temozolomide[2011/03]
French:Nouvelles formes cristallines de temozolomide[2011/03]
Examination procedure20.07.2011Application deemed to be withdrawn, date of legal effect  [2012/09]
20.09.2011Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2012/09]
Parent application(s)   TooltipEP04806720.1  / EP1706407
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20040806720) is  07.11.2008
Fees paidRenewal fee
21.09.2010Renewal fee patent year 03
21.09.2010Renewal fee patent year 04
21.09.2010Renewal fee patent year 05
21.09.2010Renewal fee patent year 06
03.12.2010Renewal fee patent year 07
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Documents cited:Search[X]FR2511679  (MAY & BAKER LTD [GB]) [X] 1-8 * Claims 1-7; Formula (I); Compound A; examples 1, 4, 9 *;
 [X]  - LOWE, P. R. ET AL., "Antitumor imidazotetrazines. 25. Crystal structure of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) and structural comparisons with the related drugs mitozolomide and DTIC", JOURNAL OF MEDICINAL CHEMISTRY, (1992), vol. 35, no. 18, pages 3377 - 3382, XP002327080 [X] 1-8 * Compound 5; Fig. 2-3; Table II *

DOI:   http://dx.doi.org/10.1021/jm00096a013
 [X]  - WANG, HAINA ET AL., "Preparation and thermostability of polymorphs of temozolomide", ZHONGGUO YIYAO GONGYE ZAZHI, (2003), vol. 34, no. 4, pages 178 - 180, XP001206278 [X] 1-8 * the whole document *
 [A]  - BRITAIN ET AL, "Polymorphism in Pharmaceutical Solids passage", POLYMORPHISM IN PHARMACEUTICAL SOLIDS, (1999), pages 235 - 238, XP002278123 [A] 1-8 * p. 236, l. 18-22 *
 [A]  - CAIRA M R, "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS", TOPICS IN CURRENT CHEMISTRY, SPRINGER, BERLIN, DE, (1998), vol. 198, ISSN 0340-1022, pages 163 - 208, XP001156954 [A] 1-8 * p. 164, paragraph 1; p. 165, paragraph 2; p. 165, last paragraph - p. 166, paragraph 1 *

DOI:   http://dx.doi.org/10.1007/3-540-69178-2_5
 [A]  - RODRIGUEZ-HORNEDO N ET AL, "SIGNIFICANCE OF CONTROLLING CRYSTALLIZATION MECHANISMS AND KINETICS IN PHARMACEUTICAL SYSTEMS", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, (19990701), vol. 88, no. 7, doi:10.1021/JS980490H, ISSN 0022-3549, pages 651 - 660, XP001096590 [A] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1021/js980490h
 [A]  - SHEKUNOV B Y ET AL, "Crystallization processes in pharmaceutical technology and drug delivery design", JOURNAL OF CRYSTAL GROWTH, ELSEVIER, AMSTERDAM, NL, (20000401), vol. 211, no. 1-4, doi:10.1016/S0022-0248(99)00819-2, ISSN 0022-0248, pages 122 - 136, XP004193361 [A] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0022-0248(99)00819-2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.