EP2258400 - Multivalent VLA-4 antagonists comprising polymer moieties [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 10.07.2015 Database last updated on 14.06.2024 | Most recent event Tooltip | 10.07.2015 | Application deemed to be withdrawn | published on 12.08.2015 [2015/33] | Applicant(s) | For all designated states ELAN PHARMACEUTICALS, INC. 800 Gateway Boulevard South San Francisco, CA 94080 / US | [2010/49] | Inventor(s) | 01 /
Konradi, Andrei, W. 30 Victoria Road Burlingame, CA 94010 / US | 02 /
Pleiss, Michael, A. 848 Stella Court Sunnyvale, CA 94087 / US | 03 /
Semko, Christopher, M. 4993 Norris Road Fremont, CA 94536 / US | 04 /
Yednock, Theodore 184 Arroyo Road Forest Knolls, CA 94933 / US | 05 /
Smith, Jenifer, L. 1770 W 13th Avenue Eugene, Oregon 97402 / US | [2011/14] |
Former [2011/08] | 01 /
Konradi, Andrei, W. 30 Victoria Road Burlingame, CA 94010 / US | ||
02 /
Pleiss, Michael, A. 848 Stella Court Sunnyvale, CA 94087 / US | |||
03 /
Semko, Christopher, M. 4993 Norris Road Fremont, CA 94536 / US | |||
04 /
Yednock, Theodore 184 Arroyo Road Forest Knolls, CA 94933 / US | |||
05 /
Smith, Jenifer, L. 1770 W 13th Avenue Eugene, Oregon 97402 / US | |||
Former [2010/49] | 01 /
Konradi, Andrei, W. 30 Victoria Road Burlingame, CA 94010 / US | ||
02 /
Pleiss, Michael, A. 848 Stella Court Sunnyvale, CA 94087 / US | |||
03 /
Semko, Christopher, M. 4993 Norris Road Fremont, CA 94536 / US | |||
04 /
Yednock, Theodore 184 Arroyo Road Forest Knolls, CA 94933 / US | |||
05 /
Smith, Jenifer, L. 512 Cortesti Avenue San Francisco, CA 94080 / US | Representative(s) | Smaggasgale, Gillian Helen, et al WP Thompson 138 Fetter Lane London EC4A 1BT / GB | [N/P] |
Former [2011/08] | Smaggasgale, Gillian Helen, et al W.P. Thompson & Co 55 Drury Lane London WC2B 5SQ / GB | ||
Former [2010/49] | Smaggasgale, Gillian Helen W.P. Thompson & Co 55 Drury Lane London WC2B 5SQ / GB | Application number, filing date | 10180274.2 | 08.07.2005 | [2010/49] | Priority number, date | US20040586975P | 08.07.2004 Original published format: US 586975 P | [2010/49] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2258400 | Date: | 08.12.2010 | Language: | EN | [2010/49] | Type: | A3 Search report | No.: | EP2258400 | Date: | 10.08.2011 | [2011/32] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 13.07.2011 | Classification | IPC: | A61K47/48, A61P37/00 | [2010/49] | CPC: |
A61K31/785 (EP,KR,US);
C07D417/12 (KR);
A61K45/06 (US);
A61K47/50 (KR);
A61K47/60 (EP,US);
A61P1/00 (EP);
A61P1/02 (EP);
A61P1/04 (EP);
A61P1/16 (EP);
A61P11/00 (EP);
A61P11/02 (EP);
A61P11/06 (EP);
A61P13/02 (EP);
A61P13/10 (EP);
A61P17/00 (EP);
A61P17/04 (EP);
A61P17/06 (EP);
A61P19/02 (EP);
A61P21/00 (EP);
A61P25/00 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P29/00 (EP);
A61P3/10 (EP);
A61P31/12 (EP);
A61P31/18 (EP);
A61P35/00 (EP);
A61P35/04 (EP);
A61P37/00 (EP);
A61P37/02 (EP);
A61P37/04 (EP);
A61P37/06 (EP);
A61P37/08 (EP);
A61P5/00 (EP);
A61P5/14 (EP);
A61P7/06 (EP);
A61P9/00 (EP);
A61P9/04 (EP);
A61P9/10 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2010/49] | Extension states | AL | Not yet paid | BA | Not yet paid | HR | Not yet paid | MK | Not yet paid | YU | Not yet paid | Title | German: | Multivalente VLA-4-Antagonisten enthaltend Polymeren | [2010/49] | English: | Multivalent VLA-4 antagonists comprising polymer moieties | [2010/49] | French: | Antagonistes multivalents de l'antigène VLA-4 comprénant des polymères | [2010/49] | Examination procedure | 10.02.2012 | Examination requested [2012/12] | 01.06.2012 | Amendment by applicant (claims and/or description) | 04.03.2013 | Despatch of a communication from the examining division (Time limit: M06) | 03.09.2013 | Reply to a communication from the examining division | 03.02.2015 | Application deemed to be withdrawn, date of legal effect [2015/33] | 24.03.2015 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2015/33] | Parent application(s) Tooltip | EP05770402.5 / EP1765412 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20050770402) is 22.01.2008 | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 01.06.2012 | Request for further processing filed | 01.06.2012 | Full payment received (date of receipt of payment) Request granted | 28.06.2012 | Decision despatched | Fees paid | Renewal fee | 27.09.2010 | Renewal fee patent year 03 | 27.09.2010 | Renewal fee patent year 04 | 27.09.2010 | Renewal fee patent year 05 | 27.09.2010 | Renewal fee patent year 06 | 12.07.2011 | Renewal fee patent year 07 | 13.07.2012 | Renewal fee patent year 08 | 10.07.2013 | Renewal fee patent year 09 | Penalty fee | Additional fee for renewal fee | 31.07.2014 | 10   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]WO0154690 (BIOGEN INC [US], et al) [A] 1-22 * Claims *; | [AP]WO2005000244 (ELAN PHARM INC [US], et al) [AP] 1-22 * page 268 line 9-page 279; page 613-618 *; | [A] - HURYN D M ET AL, Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, PAGE(S) 1651-1654, (200404), ISSN 0960-894X, XP002327663 [A] 1-22 * abstract * * page 1653, column 1, paragraph 2; figure 1 * DOI: http://dx.doi.org/10.1016/j.bmcl.2004.01.062 | [AP] - PEPINSKY R. B. ET AL, "Design, synthesis and analysis of a polyethylene glycol-modified (PEGylated) small molecule inhibitor of integrin a4b1 with improved pharmaceutical properties", JOURNAL OF PHARMOCOLOGY AND EXPERIMENTAL THERAPEUTICS, (20050201), vol. 312, no. 2, pages 742 - 750, XP008067961 [AP] 1-22 * see discussion; page 744, column 1; figures 1,2; tables 1,2 * DOI: http://dx.doi.org/10.1124/jpet.104.075648 | by applicant | US4235871 | US4501728 | US4837028 | US5011472 | US5023252 | WO9216555 | US5177059 | US5824701 | WO9853817 | US5880131 | WO0154690 | US6436904 | US6489300 | US6664331 | US2004043030 | US6716821 | - SPRINGER, T. A., NATURE, (1990), vol. 346, page 425 | - SPRINGER, T. A., CELL, (1994), vol. 76, page 301 | - OSBORNE, L., CELL, (1990), vol. 62, page 3 | - HUMPHRIES, M. J. ET AL., CIBA FOUNDATION SYMPOSIUM, (1995), vol. 189, page 177 | - YEDNOCK, T. A. ET AL., NATURE, (1992), vol. 356, page 63 | - HOLZMANN, B; WEISSMAN, I., EMBO J., (1989), vol. 8, page 1735 | - BERLIN, C. ET AL., CELL, (1993), vol. 74, page 185 | - YANG, X-D. ET AL., PNAS, (1994), vol. 91, page 12604 | - KAMEDA, Y. ET AL., BIOMATERIALS, (2004), vol. 25, pages 3259 - 3266 | - THANOU, M. ET AL., CURRENT OPINION IN INVESTIGATIONAL DRUGS, (2003), vol. 4, no. 6, pages 701 - 709 | - VERONESE, F.M. ET AL., II FARMACO, (1999), vol. 54, pages 497 - 516 | - TETRAHEDRON LETTERS, (1993), vol. 34, no. 48, page 7685 | - PAUL ET AL., TRANSPLANT INTERNATIONAL, (1996), vol. 9, pages 420 - 425 | - GEORCZYNSKI ET AL., IMMUNOLOGY, (1996), vol. 87, pages 573 - 580 | - GEORCYZNSKI ET AL., TRANSPLANT. IMMUNOL., (1995), vol. 3, pages 55 - 61 | - YANG ET AL., TRANSPLANTATION, (1995), vol. 60, pages 71 - 76 | - ANDERSON ET AL., APMIS, (1994), vol. 102, pages 23 - 27 | - SCHLEGEL ET AL., J. IMMUNOL., (1995), vol. 155, pages 3856 - 3865 | - STEINBACK ET AL., UROL. RES., (1995), vol. 23, pages 175 - 83 | - OROSZ ET AL., INT. J. CANCER, (1995), vol. 60, pages 867 - 71 | - FREEDMAN ET AL., LEUK. LYMPHOMA, (1994), vol. 13, pages 47 - 52 | - OKAHARA ET AL., CANCER RES., (1994), vol. 54, pages 3233 - 6 | - VERHOEF ET AL., EUR. J. DRUG METAB. PHARMACOKINET., (1990), vol. 15, no. 2, pages 83 - 93 | - M. H. GRAYSON ET AL., J. EXP. MED., (1998), vol. 188, no. 11, pages 2187 - 2191 | - M. PANG ET AL., ARTHRITIS RHEUM., (1998), vol. 41, no. 8, pages 1456 - 1463 | - D. ELEWAUT ET AL., SCAND J. GASTROENTEROL, (1998), vol. 33, no. 7, pages 743 - 748 | - U. KRONELD ET AL., SCAND J. GASTROENTERO, (1998), vol. 27, no. 3, pages 215 - 218 | - SCAND J. GASTROENTEROL, (1996), vol. 44, no. 3, pages 293 - 298 | - H. CHEN ET AL., CHEM. BIOL., (1999), vol. 6, pages 1 - 10 | - BELKA ET AL., BR. J. CANCER, (2001), vol. 85, pages 1233 - 9 | - HOPEWELL, ADV. SPACE RES., (1994), vol. 14, pages 433 - 42 | - PRUSINER, SCIENCE, (1982), vol. 216, pages 136 - 44 |