blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2336361

EP2336361 - KIT FOR RECOMBINASE POLYMERASE AMPLIFICATION [Right-click to bookmark this link]
Former [2011/25]Kit for recombinase polymerase amplification
[2018/34]
StatusNo opposition filed within time limit
Status updated on  05.12.2019
Database last updated on 27.07.2024
FormerThe patent has been granted
Status updated on  21.12.2018
FormerGrant of patent is intended
Status updated on  28.07.2018
FormerExamination is in progress
Status updated on  27.01.2017
Most recent event   Tooltip09.07.2021Lapse of the patent in a contracting state
New state(s): HU
published on 11.08.2021  [2021/32]
Applicant(s)For all designated states
Alere San Diego, Inc.
9975 Summers Ridge Road
San Diego, CA 92121 / US
[2019/04]
Former [2012/10]For all designated states
Alere San Diego, Inc.
9975 Summers Ridge Road
San Diego, CA 92121 / US
Former [2011/25]For all designated states
ASM Scientific, Inc.
240 Norfolk Street
Cambridge, MA 02139 / US
Inventor(s)01 / Piepenburg, Olaf
15 Highfields
Saffron Walden, Essex CB10 2AD / GB
02 / Williams, Colin H.
3 Spruce Road
Aylesbury, Buckinghamshire HP19 7AE / GB
03 / Armes, Niall
Dunwich House
Little Walden Road
Saffron Walden Essex CB10 1UX / GB
04 / Stemple, Derek L.
292 Hatfield Road
St. Albans Hertfordshire AL1 4UN / GB
 [2019/04]
Former [2011/25]01 / Piepenburg, Olaf
15 Highfields
Saffron Walden, Essex CB10 2AD / GB
02 / Williams, Colin H.
3 Spruce Road
Aylesbury, Buckinghamshire HP19 7AE / GB
03 / Armes, Niall
Dunwich House, Little Walden Road
Saffron Walden Essex CB10 1UX / GB
04 / Stemple, Derek L.
292 Hatfield Road
St. Albans Hertfordshire AL1 4UN / GB
Representative(s)Rai, Monika
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2019/04]Patent Boutique LLP
10A Printing House Yard
Hackney Road
London E2 7PR / GB
Former [2013/15]Wilkinson, Marc George, et al
Avidity IP
Kestrel House
Falconry Court
Baker's Lane
Epping, Essex CM16 5DQ / GB
Former [2011/25]Broughton, Jon Philip, et al
HLBBshaw Merlin House Falconry Court Baker's Lane Epping
Essex CM16 5DQ / GB
Application number, filing date10180482.111.04.2005
[2011/25]
Priority number, dateUS20040576148P01.06.2004         Original published format: US 576148 P
US20040576162P01.06.2004         Original published format: US 576162 P
US2004093191601.09.2004         Original published format: US 931916
US20040622291P26.10.2004         Original published format: US 622291 P
US20040632746P02.12.2004         Original published format: US 632746 P
[2011/25]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2336361
Date:22.06.2011
Language:EN
[2011/25]
Type: A3 Search report 
No.:EP2336361
Date:06.07.2011
[2011/27]
Type: B1 Patent specification 
No.:EP2336361
Date:23.01.2019
Language:EN
[2019/04]
Search report(s)(Supplementary) European search report - dispatched on:EP08.06.2011
ClassificationIPC:C12Q1/6827, C12Q1/6844
[2018/32]
CPC:
B82Y5/00 (EP); C12Q1/6827 (EP); C12Q1/6844 (EP);
B01L3/5023 (EP); B01L7/00 (EP); B82Y10/00 (EP)
C-Set:
C12Q1/6827, C12Q2521/507 (EP);
C12Q1/6844, C12Q2521/507, C12Q2522/101, C12Q2527/125, C12Q2531/119 (EP)
Former IPC [2011/25]C12Q1/68
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2019/04]
Former [2011/25]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:KIT FÜR REKOMBINASE-POLYMERASE-AMPLIFIKATION[2018/36]
English:KIT FOR RECOMBINASE POLYMERASE AMPLIFICATION[2018/36]
French:KIT APPROPRIÉ POUR AMPLIFICATION PAR RECOMBINASE ET POLYMÉRASE[2018/36]
Former [2011/25]Kit für Rekombinase-Polymerase-Amplifikation
Former [2011/25]Kit for recombinase polymerase amplification
Former [2011/25]Kit approprié pour amplification par recombinase et polymérase
Examination procedure06.01.2012Examination requested  [2012/07]
04.04.2012Amendment by applicant (claims and/or description)
21.09.2012Despatch of a communication from the examining division (Time limit: M06)
10.07.2013Reply to a communication from the examining division
30.05.2014Despatch of a communication from the examining division (Time limit: M06)
08.12.2014Reply to a communication from the examining division
18.06.2015Despatch of a communication from the examining division (Time limit: M02)
28.08.2015Reply to a communication from the examining division
27.11.2015Observations by third parties
01.03.2016Despatch of a communication from the examining division (Time limit: M06)
17.08.2016Reply to a communication from the examining division
08.09.2016Observations by third parties
17.01.2017Despatch of a communication from the examining division (Time limit: M06)
27.07.2017Reply to a communication from the examining division
28.11.2017Despatch of a communication from the examining division (Time limit: M04)
04.04.2018Reply to a communication from the examining division
06.08.2018Communication of intention to grant the patent
14.12.2018Fee for grant paid
14.12.2018Fee for publishing/printing paid
14.12.2018Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP05741662.0  / EP1759012
Divisional application(s)EP19153024.5  / EP3540073
EP21192246.3
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20050741662) is  08.11.2007
Opposition(s)24.10.2019No opposition filed within time limit [2020/01]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
10.07.2013Request for further processing filed
10.07.2013Full payment received (date of receipt of payment)
Request granted
22.07.2013Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
04.04.2012Request for further processing filed
04.04.2012Full payment received (date of receipt of payment)
Request granted
18.04.2012Decision despatched
Fees paidRenewal fee
27.09.2010Renewal fee patent year 03
27.09.2010Renewal fee patent year 04
27.09.2010Renewal fee patent year 05
27.09.2010Renewal fee patent year 06
12.04.2011Renewal fee patent year 07
30.03.2012Renewal fee patent year 08
12.04.2013Renewal fee patent year 09
25.03.2014Renewal fee patent year 10
10.04.2015Renewal fee patent year 11
11.04.2016Renewal fee patent year 12
10.04.2017Renewal fee patent year 13
11.04.2018Renewal fee patent year 14
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU11.04.2005
AT23.01.2019
CY23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SI23.01.2019
SK23.01.2019
TR23.01.2019
IE11.04.2019
LU11.04.2019
BG23.04.2019
GR24.04.2019
BE30.04.2019
CH30.04.2019
LI30.04.2019
IS23.05.2019
PT23.05.2019
[2021/32]
Former [2021/26]AT23.01.2019
CY23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SI23.01.2019
SK23.01.2019
TR23.01.2019
IE11.04.2019
LU11.04.2019
BG23.04.2019
GR24.04.2019
BE30.04.2019
CH30.04.2019
LI30.04.2019
IS23.05.2019
PT23.05.2019
Former [2020/21]AT23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SI23.01.2019
SK23.01.2019
TR23.01.2019
IE11.04.2019
LU11.04.2019
BG23.04.2019
GR24.04.2019
BE30.04.2019
CH30.04.2019
LI30.04.2019
IS23.05.2019
PT23.05.2019
Former [2020/17]AT23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SI23.01.2019
SK23.01.2019
TR23.01.2019
LU11.04.2019
BG23.04.2019
GR24.04.2019
BE30.04.2019
CH30.04.2019
LI30.04.2019
IS23.05.2019
PT23.05.2019
Former [2020/11]AT23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SI23.01.2019
SK23.01.2019
LU11.04.2019
BG23.04.2019
GR24.04.2019
BE30.04.2019
CH30.04.2019
LI30.04.2019
IS23.05.2019
PT23.05.2019
Former [2020/04]AT23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SK23.01.2019
LU11.04.2019
BG23.04.2019
GR24.04.2019
IS23.05.2019
PT23.05.2019
Former [2020/03]AT23.01.2019
CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SK23.01.2019
BG23.04.2019
GR24.04.2019
IS23.05.2019
PT23.05.2019
Former [2020/02]CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
MC23.01.2019
PL23.01.2019
RO23.01.2019
SK23.01.2019
BG23.04.2019
GR24.04.2019
IS23.05.2019
PT23.05.2019
Former [2019/49]CZ23.01.2019
DK23.01.2019
EE23.01.2019
FI23.01.2019
LT23.01.2019
PL23.01.2019
RO23.01.2019
SK23.01.2019
BG23.04.2019
GR24.04.2019
IS23.05.2019
PT23.05.2019
Former [2019/48]DK23.01.2019
FI23.01.2019
LT23.01.2019
PL23.01.2019
BG23.04.2019
GR24.04.2019
IS23.05.2019
PT23.05.2019
Former [2019/39]FI23.01.2019
LT23.01.2019
PL23.01.2019
BG23.04.2019
GR24.04.2019
IS23.05.2019
PT23.05.2019
Former [2019/38]FI23.01.2019
LT23.01.2019
PL23.01.2019
BG23.04.2019
GR24.04.2019
PT23.05.2019
Former [2019/37]FI23.01.2019
LT23.01.2019
PL23.01.2019
GR24.04.2019
PT23.05.2019
Former [2019/35]FI23.01.2019
LT23.01.2019
PL23.01.2019
PT23.05.2019
Former [2019/33]FI23.01.2019
LT23.01.2019
PT23.05.2019
Documents cited:Search[AD]US5223414  (ZARLING DAVID A [US], et al) [AD] 1-31 * the whole document *;
 [A]US2003143525  (BENKOVIC STEPHEN J [US], et al) [A] 1-31 * the whole document *;
 [XYI]WO03072805  (ASM SCIENT INC [US], et al) [X] 1-3,7-9,12,16-22,25-29 * the whole document * * page 24 - page 25; figure 1; example 1 * * page 27 * * page 33 * [Y] 13-15 [I] 4,10,11,23,24,30,31;
 [YD]  - LAVERY P E ET AL, "ENHANCEMENT OF RECA PROTEIN-PROMOTED DNA STRAND EXCHANGE ACTIVITY BY VOLUME-OCCUPYING AGENTS", JOURNAL OF BIOLOGICAL CHEMISTRY, (1992), vol. 267, no. 13, ISSN 0021-9258, pages 9307 - 9314, XP002637593 [YD] 13-15 * the whole document * * page 9309, column r * * page 9311, column r *
 [Y]  - ZIMMERMAN S B ET AL, "MACROMOLECULAR CROWDING INCREASES BINDING OF DNA POLYMERASE TO DNA AN ADAPTIVE EFFECT", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (1987), vol. 84, no. 7, ISSN 0027-8424, pages 1871 - 1875, XP002637594 [Y] 13-15 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.84.7.1871
 [Y]  - AMASINO ET AL, "Acceleration of nucleic acid hybridization rate by polyethylene glycol", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, vol. 152, no. 2, doi:10.1016/0003-2697(86)90413-6, ISSN 0003-2697, (19860201), pages 304 - 307, (19860201), XP024818286 [Y] 13-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/0003-2697(86)90413-6
 [Y]  - MINTON ALLEN P, "The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media", JOURNAL OF BIOLOGICAL CHEMISTRY, (20010406), vol. 276, no. 14, ISSN 0021-9258, pages 10577 - 10580, XP002637595 [Y] 13-15 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.R100005200
 [Y]  - ELLIS R J, "Macromolecular crowding: obvious but underappreciated", TRENDS IN BIOCHEMICAL SCIENCES, ELSEVIER, HAYWARDS, GB, (20011001), vol. 26, no. 10, doi:10.1016/S0968-0004(01)01938-7, ISSN 0968-0004, pages 597 - 604, XP004335875 [Y] 13-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0968-0004(01)01938-7
 [A]  - SALINAS F ET AL, "Characterization of bacteriophage T4-coordinated leading- and lagging-strand synthesis on a minicircle substrate.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 20 JUN 2000, (20000620), vol. 97, no. 13, ISSN 0027-8424, pages 7196 - 7201, XP002365102 [A] 1-31 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.97.13.7196
 [A]  - BIANCO P R ET AL, "DNA STRAND EXCHANGE PROTEINS: A BIOCHEMICAL AND PHYSICAL COMPARISON", FRONTIERS IN BIOSCIENCE, FRONTIERS IN BIOSCIENCE, ALBERTSON, NY, US, (19980601), vol. 3, ISSN 1093-9946, pages D570 - D603, XP008063175 [A] 1-31 * the whole document *
 [T]  - PIEPENBURG OLAF ET AL, "DNA detection using recombination proteins", PLOS BIOLOGY, PUBLIC LIBRARY OF SCIENCE, US, vol. 4, no. 7, doi:10.1371/JOURNAL.PBIO.0040204, ISSN 1544-9173, (20060701), page E204.1121, (20060613), XP002501560

DOI:   http://dx.doi.org/10.1371/JOURNAL.PBIO.0040204
ExaminationWO9305178
 WO9720078
 US5705366
 WO03027640
 US2004058378
 EP1403379
    - F. A. Kadyrov ET AL, "Properties of Bacteriophage T4 Proteins Deficient in Replication Repair", Journal of Biological Chemistry, US, (20030627), vol. 278, no. 27, doi:10.1074/jbc.M302564200, ISSN 0021-9258, pages 25247 - 25255, XP055252494

DOI:   http://dx.doi.org/10.1074/jbc.M302564200
    - KOZER N ET AL, "Effect of Crowding on Protein-Protein Association Rates: Fundamental Differences between Low and High Mass Crowding Agents", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20040220), vol. 336, no. 3, doi:10.1016/J.JMB.2003.12.008, ISSN 0022-2836, pages 763 - 774, XP004487354

DOI:   http://dx.doi.org/10.1016/j.jmb.2003.12.008
    - Michael K. Reddy ET AL, "Using macromolecular crowding agents to identify weak interactions within DNA replication complexes", METHODS IN ENZYMOLOGY, US, ACADEMIC PRESS, (19950101), vol. 262, pages 466 - 476, doi:10.1016/0076-6879(95)62038-9, ISSN 0076-6879, XP055252539

DOI:   http://dx.doi.org/10.1016/0076-6879(95)62038-9
by applicantUS5223414
 US5273881
 US5460941
 WO02086167
 WO03072805
    - PAULUS, B. F.; BRYANT, F. R., BIOCHEMISTRY, (1997), vol. 36, pages 7832 - 8
    - ROSSELLI, W.; STASIAK, A., J MOL BIOL, (1990), vol. 216, pages 335 - 52
    - SHAN, Q. ET AL., J MOL BIOL, (1997), vol. 265, pages 519 - 40
    - MAZIN, A. V; KOWALCZYKOWSKI, S. C., EMBO J, (1998), vol. 17, pages 1161 - 8
    - BUTLER BC; HANCHETT RH; RAFAILOV H; MACDONALD G, "Investigating Structural Changes Induced By Nucleotide Binding to RecA Using Difference FTIR", BIOPHYS J, (2002), vol. 82, no. 4, pages 2198 - 2210
    - OLEG N. VOLOSHIN; LIJANG WANG; R. DANIEL CAMERINI-OTERO, "Homologous DNA pairing Promoted by a 20-amino Acid Peptide Derived from RecA", SCIENCE, (19960510), vol. 272
    - BORK; COX; INMAN, J BIOL CHEM., (20011207), vol. 276, no. 49, pages 45740 - 3
    - BORK; COX; INMAN, EMBO J., (20011217), vol. 20, no. 24, pages 7313 - 22
    - MORRICAL; ALBERTS, J BIOL CHEM., (19900905), vol. 265, no. 25, pages 15096 - 103
    - FORMOSA; ALBERTS, CELL, (19861205), vol. 47, no. 5, pages 793 - 806
    - REDDY; WEITZEL; VON HIPPEL, PROC NATL ACAD SCI U S A., (19930415), vol. 90, no. 8, pages 3211 - 5
    - HACKER; ALBERTS, J BIOL CHEM., (19921015), vol. 267, no. 29, pages 20674 - 81
    - EGGLER; LUSETTI; COX, J BIOL CHEM., (20030220), vol. 278, no. 18, pages 16389 - 96
    - VILLEMAIN ET AL., J BIOL CHEM., (20001006), vol. 275, no. 40, pages 31496 - 504
    - SANGER, F.; NICHLEN, S.; COULSON, A. R., PROC. NATL. ACAD. SCI. U.S.A., (1977), vol. 75, pages 5463 - 5467
    - MAXAM, A. M.; GILBERT, W., PROC NATL ACAD SCI USA, (1977), vol. 74, pages 560 - 564
    - RONAGHI, M.; UHLEN, M.; NYREN, P., SCIENCE, (1998), vol. 281, page 363,365
    - LYSOV, I.; FLORENT'EV, V. L.; KHORLIN, A.A.; KHRAPKO, K. R.; SHIK, V. V., DOKL AKAD NAUK SSSR, (1988), vol. 303, pages 1508 - 1511
    - BAINS W.; SMITH G. C., J. THEOR. BIOL, (1988), vol. 135, pages 303 - 307
    - DMANAC, R.; LABAT, I.; BRUKNER, I.; CRKVENJAKOV, R., GENOMICS, (1989), vol. 4, pages 114 - 128
    - KHRAPKO, K. R.; LYSOV, Y.; KHORLYN, A. A.; SHICK, V. V.; FLORENTIEV, V. L.; MIRZABEKOV, A. D., FEBS LETT, (1989), vol. 256, pages 118 - 122
    - PEVZNER P. A., J BIOMOL STRUCT DYN, (1989), vol. 7, pages 63 - 73
    - SOUTHERN, E. M.; MASKOS, U.; ELDER, J. K., GENOMICS, (1992), vol. 13, pages 1008 - 1017
    - SCHEERHAGEN ET AL., J BIOMOL STRUCT DYN., (198604), vol. 3, no. 5, pages 887 - 98
    - KUIL ET AL., BIOPHYS CHEM., (198812), vol. 32, no. 2-3, pages 211 - 27
    - FERRARI ET AL., J MOL BIOL., (19940211), vol. 236, no. 1, pages 106 - 23
    - LOHMAN; FERRARI, ANNU REV BIOCHEM., (1994), vol. 63, pages 527 - 70
    - LAVERY PE; KOWALCZYKOWSKI SC, J BIOL CHEM., (19920505), vol. 267, no. 13, pages 9307 - 14
    - HARRIS LD; GRIFFITH J., J BIOL CHEM., (19870705), vol. 262, no. 19, pages 9285 - 92
    - HSIEH P; CAMERINI-OTERO CS; CAMERINI-OTERO RD, PROC NATL ACAD SCI U S A., (19920715), vol. 89, no. 14, pages 6492 - 6
    - KATZ FS; BRYANT FR, BIOCHEMISTRY, (20010918), vol. 40, no. 37, pages 11082 - 9
    - FORMOSA T; ALBERTS BM, J BIOL CHEM., (19860505), vol. 261, no. 13, pages 6107 - 18
    - SALINAS F; JIANG H; KODADEK T, J BIOL CHEM., (19950310), vol. 270, no. 10, pages 5181 - 6
    - MORRICAL SW; WONG ML; ALBERTS BM, J BIOL CHEM., (19910725), vol. 266, no. 21, pages 14031 - 8
    - FORMOSA; ALBERTS, PNAS, (1983), vol. 80, pages 2442 - 2446
    - JBC, (19910525), vol. 266, no. 15, pages 9712 - 8
    - ELIAS-AMANZ M; SALAS M., EMBO J., (19970915), vol. 16, no. 18, pages 5775 - 83
    - FORMOSA T; ALBERTS BM, CELL, (19861205), vol. 47, no. 5, pages 793 - 806
    - XU L; MARIANS KJ, J BIOL CHEM., (20020419), vol. 277, no. 16, pages 14321 - 8
    - HACKER KJ; ALBERTS BM, J BIOL CHEM., (19921015), vol. 267, no. 29, pages 20674 - 81
    - HEID CA; STEVENS J; LIVAK KJ; WILLIAMS PM, "Real time quantitative PCR", GENOME RES., (1996), vol. 6, pages 986 - 94
    - ADAMS, D. E.; TSANEVA, I. R.; WEST, S. C., "Dissociation of RecA filaments from duplex DNA by the RuvA and RuvB DNA repair proteins", PROC NATL ACAD SCI U S A, (1994), vol. 91, pages 9901 - 5
    - ALEXSEYEV, A. A.; BAKHLANOVA, I. V.; ZAITSEV, E. N.; LANZOV, V. A., "Genetic characteristics of new RecA mutants of Escherichia coli K-12", J BACTERIOL, (1996), vol. 178, pages 2018 - 24, XP002638329
    - BAR-ZIV R; LIBCHABER A, "Effects of DNA sequence and structure on binding of RecA to single-stranded DNA", PNAS USA, (20010731), vol. 98, no. 16, doi:doi:10.1073/PNAS.151242898, pages 9068 - 73, XP002547311

DOI:   http://dx.doi.org/10.1073/PNAS.151242898
    - BAUMANN, P.; BENSON, F. E.; HAJIBAGHERI, N.; WEST, S. C., "Purification of human Rad51 protein by selective spennidine precipitation", MUTAT RES, (1997), vol. 384, pages 65 - 72
    - BENKOVIC, S. J.; VALENTINE, A. M.; SALINAS, F., "Replisome-mediated DNA replication", ANNU REV BIOCHEM, (2001), vol. 70, doi:doi:10.1146/annurev.biochem.70.1.181, pages 181 - 208, XP001179790

DOI:   http://dx.doi.org/10.1146/annurev.biochem.70.1.181
    - BENNETT, R. L.; HOLLOMAN, W. K., "A RecA homologue in Ustilago maydis that is distinct and evolutionarily distant from Rad51 actively promotes DNA pairing reactions in the absence of auxiliary factors", BIOCHEMISTRY, (2001), vol. 40, pages 2942 - 53
    - BETTER, M.; HELINSKI, D. R., "Isolation and characterization of the RecA gene of Rhizobium meliloti", J BACTERIOL, (1983), vol. 155, pages 311 - 6
    - BIANCO, P.R.; WEINSTOCK, G.M., "Interaction of the RecA protein of Escherichia colli with single-stranded oligodeoxyribonucleotides", NUCLEIC ACIDS RESEARCH, (19961215), vol. 24, no. 24, pages 4933 - 9
    - BORK, J. M.; COX, M. M.; INMAN, R. B., "The RecOR proteins modulate RecA protein function at 5' ends of single- stranded DNA", EMBO J, (2001), vol. 20, pages 7313 - 22
    - BYRD AK; RANEY KD, "Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA", NAT STRUCT MOL BIOL., (20040601), vol. 1, no. 6, pages 531 - 8
    - COX, M. M.; GOODMAN, M. F.; KREUZER, K. N.; SHERRATT, D. J.; SANDLER, S. J.; MARIANS, K. J., "The importance of repairing stalled replication forks", NATURE, (2000), vol. 404, pages 37 - 41
    - COX, M. M.; MCENTEE, K.; LEHMAN, I. R., "A simple and rapid procedure for the large scale purification of the RecA protein of Escherichia coli", J BIO1 CHEM, (1981), vol. 256, pages 4676 - 8
    - CROMIE, G. A.; LEACH, D. R., "Control of crossing over", MOL CELL, (2000), vol. 6, pages 815 - 26
    - DILLINGHAM, M. S.; KOWALCZYKOWSKI, S. C., "A step backward in advancing DNA replication: rescue of stalled replication forks by RecG", MOL CELL, (2001), vol. 8, pages 734 - 6
    - EGGLER; LUSETTI; COX, J BIOL CHEM., (20030502), vol. 278, no. 18, pages 16389 - 96
    - EGGLESTON, A. K.; WEST, S. C., "Cleavage of holiday junctions by the Escherichia coli RuvABC complex", J BIOL CHEM, (2000), vol. 275, pages 26467 - 76
    - ELIAS-ARNANZ M; SALAS M, EMBO J., (19970915), vol. 16, no. 18, pages 5775 - 83
    - GLOVER, B. P.; MCHENRY, C. S., "The DNA polymerase III holoenzyme: an asymmetric dimeric replicative complex with leading and lagging strand polymerases", CELL, (2001), vol. 105, pages 925 - 34
    - GOODMAN, H. J.; PARKER, J. R.; SOUTHERN, J. A.; WOODS, D. R., "Cloning and expression in Escherichia coli of a RecA-like gene from Bacteroides fragilis", GENE, (1987), vol. 58, doi:doi:10.1016/0378-1119(87)90381-7, pages 265 - 71, XP023544337

DOI:   http://dx.doi.org/10.1016/0378-1119(87)90381-7
    - HARRIS LD; GRIFFITH J, J BIOL CHEM., (19870705), vol. 262, no. 19, pages 9285 - 92
    - HEID CA; STEVENS J; LIVAK KJ; WILLIAMS PM, "Real time quantitative PCR", GENOME RES., (199610), vol. 6, no. 10, pages 986 - 94
    - HEYER, W. D.; KOLODNER, R. D., "Purification and characterization of a protein from Saccharomyces cerevisiae that binds tightly to single-stranded DNA and stimulates a cognate strand exchange protein", BIOCHEMISTRY, (1989), vol. 28, pages 2856 - 62
    - HICKSON, 1. D.; GORDON, R. L.; TOMKINSON, A. E.; EMMERSON, P. T., "A temperature sensitive RecA protein of Escherichia coli", MOL GEN GENET, (1981), vol. 184, doi:doi:10.1007/BF00271197, pages 68 - 72, XP008136787

DOI:   http://dx.doi.org/10.1007/BF00271197
    - HSIEH, P.; CAMERINI-OTERO, C. S.; CAMERINI-OTERO, R. D., "The synapsis event in the homologous pairing of DNAs: RecA recognizes and pairs less than one helical repeat of DNA", PROC NATL ACAD SCI U S A, (1992), vol. 89, pages 6492 - 6
    - KATO, R.; KURAMITSU, S., "RecA protein from an extremely thermophilic bacterium, Thermus thermophilus HB8", J BIOCHEM (TOKYO), (1993), vol. 114, pages 926 - 9, XP009053393
    - KELMAN, Z.; O'DONNELL, M., "DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machine", ANNU REV BIOCHEM, (1995), vol. 64, pages 171 - 200
    - KOMORI, K.; MIYATA, T.; DIRUGGIERO, J.; HOLLEY-SHANKS, R.; HAYASHI, I.; CANN, I. K.; MAYANAGI, K.; SHINAGAWA, H.; ISHINO, Y., "Both RadA and RadB are involved in homologous recombination in Pyrococcus furiosus", J BIOL CHEM, (2000), vol. 275, pages 33782 - 90
    - KOWALCZYKOWSKI SC; LONBERG N; NEWPORT JW; PAUL LS; VON HIPPEL PH, BIOPHYS J., (198010), vol. 32, no. 1, pages 403 - 18
    - KURAMITSU, S.; HAMAGUCHI, K.; OGAWA, T.; OGAWA, H., "A large-scale preparation and some physicochemical properties of RecA protein", J BIOCHEM (TOKYO), (1981), vol. 90, pages 1033 - 45
    - KURUMIZAKA, H.; IKAWA, S.; IKEYA, T.; OGAWA, T.; SHIBATA, T., "A chimeric RecA protein exhibits altered double-stranded DNA binding", J BIOL CHEM, (1994), vol. 269, pages 3068 - 75
    - LIU, J.; NURSE, P.; MARIANS, K. J., "The ordered assembly of the phiX174-type primosome. III. PriB facilitates complex formation between PriA and DnaT", J BIOL CHEM, (1996), vol. 271, pages 15656 - 61
    - LOVETT, C. M., JR.; ROBERTS, J. W., "Purification of a RecA protein analogue from Bacillus subtilis", J BIOL CHEM, (1985), vol. 260, pages 3305 - 13
    - MAESHIMA, K.; MORIMATSU, K.; HORII, T., "Purification and characterization of XRad51.1 protein, Xenopus RAD51 homologue: recombinant XRad51.1 promotes strand exchange reaction", GENES CELLS, (1996), vol. 1, pages 1057 - 68
    - MARIANS, K. J., "Prokaryotic DNA replication", ANNU REV BIOCHEM, (1992), vol. 61, pages 673 - 719
    - MARIANS, K. J., "PriA: at the crossroads of DNA replication and recombination", PROG NUCLEIC ACID RES MOL BIOL, (1999), vol. 63, pages 39 - 67
    - MAZIN, A. V.; KOWALCZYKOWSKI, S. C., "The function of the secondary DNA-binding site of RecA protein during DNA strand exchange", EMBO J, (1998), vol. 17, pages 1161 - 8
    - MCGLYNN, P.; LLOYD, R. G., "RecG helicase activity at three- and four-strand DNA structures", NUCLEIC ACIDS RES, (1999), vol. 27, pages 3049 - 56
    - MCGLYNN, P.; MAHDI, A. A.; LLOYD, R. G., "Characterisation of the catalytically active form of RecG helicase", NUCLEIC ACIDS RES, (2000), vol. 28, pages 2324 - 32
    - MITRA, R.; CHURCH, G., "In situ localized amplification and contact replication of many individual DNA molecules", NUCL ACIDS RES, (1999), vol. 27, no. 24, doi:doi:10.1093/nar/27.24.e34, pages E34I - VI, XP002292358

DOI:   http://dx.doi.org/10.1093/nar/27.24.e34
    - MOREL, P.; CHERNY, D.; EHRLICH, S. D.; CASSUTO, E., "Recombination-dependent repair of DNA double-strand breaks with purified proteins from Escherichia coli", J BIOL CHEM, (1997), vol. 272, pages 17091 - 6
    - MORRICAL; ALBERTS, J BIOL CHERN., (19900905), vol. 265, no. 25, pages 15096 - 103
    - MORRIS PD; RANEY KD, "DNA helicases displace streptavidin from biotin- labeled oligonucleotides", BIOCHEMISTRY, (19990420), vol. 38, no. L6, pages 5L64 - 71
    - NG, J. Y.; MARIANS, K. J., "The ordered assembly of the phiXl74-type primosome. I. Isolation and identification of intermediate protein-DNA complexes", J BIOL CHEM, (1996), vol. 271, pages 15642 - 8
    - NG, J. Y.; MARIANS, K. J., "The ordered assembly of the phiX174-type primosome. II. Preservation of primosome composition from assembly through replication", J BIOL CHEM, (1996), vol. 271, pages 15649 - 55
    - PAULUS, B. F.; BRYANT, F. R., "Time-dependent inhibition of RecA protein-catalyzed ATP hydrolysis by ATP-gammaS: evidence for a rate-determining isomerization of the RecA- ssDNA complex", BIOCHEMISTRY, (1997), vol. 36, pages 7832 - 8
    - PHAM, P.; BERTRAM, J. G.; O'DONNELL, M.; WOODGATE, R.; GOODMAN, M. F., "A model for SOS-lesion-targeted mutations in Escherichia coli", NATURE, (2001), vol. 409, doi:doi:10.1038/35053116, pages 366 - 70, XP055040261

DOI:   http://dx.doi.org/10.1038/35053116
    - PIERRE, A.; PAOLETTI, C., "Purification and characterization of RecA protein from salmonella typhimurium", J BIOL CHEM, (1983), vol. 258, pages 2870 - 4
    - RASHID, N.; MORIKAWA, M.; KANAYA, S.; ATOMI, H.; IMANAKA, T., "RecA/Rad51 homolog from Thermococcus kodakaraensis KODI", METHODS ENZYMOL, (2001), vol. 334, pages 261 - 70
    - REDDY; WEITZEL; VON HIPPEL, PROC NATL ACAD SCI U S A, (19930415), vol. 90, no. 8, pages 3211 - 5
    - RIDDLES PW; LEHMAN IR, J BIOL CHEM., (19850110), vol. 260, no. 1, pages 170 - 3
    - ROSSELLI, W.; STASIAK, A., "Energetics of RecA-mediated recombination reactions. Without ATP hydrolysis RecA can mediate polar strand exchange but is unable to recycle", J MOL BIOL, (1990), vol. 216, pages 335 - 52
    - SALINAS F; JIANG H; KODADEK T., J BIOL CHEM., (19950310), vol. 270, no. 10, pages 5181 - 6
    - SHAN, Q.; BORK, J. M.; WEBB, B. L.; INMAN, R. B.; COX, M. M., "RecA protein filaments: end-dependent dissociation from ssDNA and stabilization by RecO and RecR proteins", J MOL BIOL, (1997), vol. 265, doi:doi:10.1006/jmbi.1996.0748, pages 519 - 40, XP004462300

DOI:   http://dx.doi.org/10.1006/jmbi.1996.0748
    - SINGLETON, M. R.; SCAIFE, S.; WIGLEY, D. B., "Structural analysis of DNA replication fork reversal by RecG", CELL, (2001), vol. 107, pages 79 - 89
    - SPIES, M.; KIL, Y.; MASUI, R.; KATO, R.; KUJO, C.; OHSHIMA, T.; KURAMITSU, S.; LANZOV, V., "The RadA protein from a hyperthermophilic archaeon Pyrobaculum islandicum is a DNA-dependent ATPase that exhibits two disparate catalytic modes, with a transition temperature at 75 degrees C", EUR J BIOCHEM, (2000), vol. 267, no. 112, pages 5 - 37
    - STEFFEN; S. E.; BRYANT, F. R., "Purification and characterization of the RecA protein from Streptococcus pneumoniae", ARCH BIOCHEM BIOPHYS, (2000), vol. 382, pages 303 - 9
    - TANG, M.; PHAM, P.; SHEN, X.; TAYLOR, J. S.; O'DONNELL, M.; WOODGATE, R.; GOODMAN, M. F., "Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis", NATURE, (2000), vol. 404, pages 1014 - 8
    - TISSIER, A. F.; LOPEZ, M. F.; SIGNER, E. R., "Purification and characterization of a DNA strand transferase from broccoli", PLANT PHYSIOL, (1995), vol. 108, pages 379 - 86
    - TRACY RB; KOWALCZYKOWSKI SC, "In vitro selection of preferred DNA pairing sequences by the Escherichia coli recA protein", GENES DEV., (19960801), vol. 10, no. 15, pages 1890 - 903
    - VESTER B; WENGEL J., BIOCHEMISTRY, (20041026), vol. 43, no. 42, pages 13233 - 4
    - I VILLEMAIN ET AL., J BIOL CHEM., (20001006), vol. 275, no. 40, pages 31496 - 504
    - VOLODIN AA; CAMERINI-OTERO RD, "Influence of DNA sequence on the positioning of RecA monomers in RecA-DNA cofilaments", J BIOL CHEM., (20020111), vol. 277, no. 2, pages 1614 - 8
    - WEBB, B. L.; COX, M. M.; INMAN, R. B., "An interaction between the Escherichia coli RecF and RecR proteins dependent on ATP and double-stranded DNA", J BIOL CHEM, (1995), vol. 270, pages 31397 - 404
    - WEBB, B. L.; COX, M. M.; INMAN, R. B., "Recombinational DNA repair: the RecF and RecR proteins limit the extension of RecA filaments beyond single-strand DNA gaps", CELL, (1997), vol. 91, doi:doi:10.1016/S0092-8674(00)80418-3, pages 347 - 56, XP029990011

DOI:   http://dx.doi.org/10.1016/S0092-8674(00)80418-3
    - WEBB, B. L.; COX, M. M.; INMAN, R. B., "ATP hydrolysis and DNA binding by the Escherichia coli ReeF protein", J BIOL CHEM, (1999), vol. 274, pages 15367 - 74
    - WEST, S. C.; COUNTRYMAN, J. K; HOWARD-FLANDERS, P., "Purification and properties of the RecA protein of Proteus mirabilis. Comparison with Escherichia coli RecA protein; specificity of interaction with single strand binding protein", J BIOL CHEM, (1983), vol. 258, pages 4648 - 54
    - WETMUR, J. G.; WONG, D. M.; ORTIZ, B.; TONG, J.; REICHERT, F.; GELFAND, D. H., "Cloning, sequencing, and expression of RecA proteins from three distantly related thermophilic eubacteria", J BIOL CHEM, (1994), vol. 269, pages 25928 - 35, XP000604933
    - WITTWER CT; HERMANN M.; MOSS AA; RASMUSSEN RP, "Continuous fluorescence monitoring ofrapid cycle DNA amplification", BIOTECHNIQUES, (199701), vol. 22, no. 1, pages 130 - 1 134,8, XP000683698
    - WITTWER C.T.; RIRIE KM; ANDREW RV; DAVID DA; GUNDRY RA; BALIS UJ, "The LightCycler: a microvolume multisample fluorimeter with rapid temperature control", BIOTECHNIQUES, (199701), vol. 22, no. L, pages 176 - 81, XP002210170
    - L. D. HARRIS; J. D. GRIFFITH, J MOL BIOL, (19890305), vol. 206, pages 19 - 27
    - MITRA R; CHURCH G, "In situ localized amplification and contact replication of many individual DNA molecules", NUCL ACIDS RES, (1999), vol. 27, no. 24, doi:doi:10.1093/nar/27.24.e34, pages E34I - VI, XP002292358

DOI:   http://dx.doi.org/10.1093/nar/27.24.e34
    - R. K. SAIKI ET AL., SCIENCE, (19880129), vol. 239, pages 487 - 91
    - G. T. WALKER; M. C. LITTLE; J. G. NADEAU; D. D. SHANK, PROC ! NATL ACAD SCI U SA, (19920101), vol. 89, pages 392 - 6
    - D. Y. ZHANG; M. BRANDWEIN; T. HSUIH; H. B. LI, MOL DIAGN, (200106), vol. 6, pages 141 - 50
    - M. VINCENT; Y. XU; H. KONG, EMBO REP, (200408), vol. 5, pages 795 - 800
    - J. COMPTON, NATURE, (19910307), vol. 350, pages 91 - 2
    - T. YONESAKI; Y. RYO; T. MINAGAWA; H. TAKAHASHI, EUR J BIOCHEM, (19850401), vol. 148, pages 127 - 34
    - T. SHIBATA; C. DASGUPTA; R. P. CUNNINGHAM; C. M. RADDING, PROC NATL ACAD SCI U S A, (197904), vol. 76, pages 1638 - 42
    - P. W. RIDDLES; 1. R. LEHMAN, J BIOL CHEM, (19850110), vol. 260, pages 165 - 9
    - S. C. KOWALCZYKOWSKI; J. CLOW; R. SOMANI; A. VARGHESE, J MOL BIOL, (19870105), vol. 193, pages 81 - 95
    - A. L. EGGLER; S. L. LUSETTI; M. M. COX, J BIOL CHEM, (20030502), vol. 278, pages 16389 - 96
    - T. SHIBATA; C. DASGUPTA; R. P. CUNNINGHAM; C. M. RADDING, PROC NATL ACAD SCI U S A, (198005), vol. 77, pages 2606 - 10
    - L. XU; K. J. MARIANS, J BIOL CHEM, (20020419), vol. 277, pages 14321 - 8
    - P. W. RIDDLES; I. R. LEHMAN, J BIOL CHEM, (19850110), vol. 260, pages 170 - 3
    - P. E. LAVERY; S. C. KOWALCZYKOWSKI, J BIOL CHEM, (19920505), vol. 267, pages 9307 - 14
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.