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Extract from the Register of European Patents

EP About this file: EP2484766

EP2484766 - Method for producing a target protein connected with a heterogeneous ferritin protein using yeast host cells [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.05.2014
Database last updated on 13.09.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Artes Biotechnology GmbH
Elisabeth-Selbert-Strasse 9
40764 Langenfeld / DE
[2013/27]
Former [2012/32]For all designated states
Artes Biotechnologie GmbH
Elisabeth-Selbert-Strasse 9
40764 Langenfeld / DE
Inventor(s)01 / Suckow, Manfred, Dr.
Urdenbacher Dorfstr. 39
40593 Düsseldorf / DE
02 / Eilert, Eva
Aachener Str. 101
40223 Düsseldorf / DE
03 / Piontek, Michael, Dr.
Herder Str. 39
42549 Velbert / DE
 [2012/32]
Representative(s)Zenz Patentanwälte Partnerschaft mbB
Gutenbergstraße 39
45128 Essen / DE
[N/P]
Former [2012/32]Zenz
Patent- und Rechtsanwälte Rüttenscheider Straße 2
45128 Essen / DE
Application number, filing date10180732.928.09.2010
[2012/32]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP2484766
Date:08.08.2012
Language:DE
[2012/32]
Type: B1 Patent specification 
No.:EP2484766
Date:03.07.2013
Language:DE
[2013/27]
Search report(s)(Supplementary) European search report - dispatched on:EP11.07.2012
ClassificationIPC:C12N15/81, C12R1/645, C12N1/16
[2012/32]
CPC:
C12N15/81 (EP); C12P21/02 (EP); C07K2319/01 (EP);
C07K2319/35 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/32]
TitleGerman:Verfahren zum Herstellen eines Ziel-Proteins im Verbund mit einem heterologen Ferritin-Protein unter Verwendung von Hefe-Wirtszellen[2012/32]
English:Method for producing a target protein connected with a heterogeneous ferritin protein using yeast host cells[2012/32]
French:Procédé de fabrication d'une protéine cible en relation avec une protéine de ferritine hétérologue en utilisant des cellules-hôtes de levure[2012/32]
Examination procedure15.08.2012Examination requested  [2012/39]
14.02.2013Communication of intention to grant the patent
16.05.2013Fee for grant paid
16.05.2013Fee for publishing/printing paid
Appeal following examination11.03.2011Appeal received No.  J0007/11
11.03.2011Statement of grounds filed
24.01.2012Result of appeal procedure: allowance of appeal
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.02.2013
Opposition(s)04.04.2014No opposition filed within time limit [2014/24]
Fees paidRenewal fee
01.10.2012Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU28.09.2010
AL03.07.2013
BG03.07.2013
CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
MK03.07.2013
MT03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
SM03.07.2013
TR03.07.2013
IE28.09.2013
LU28.09.2013
BE30.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
[2018/46]
Former [2015/34]HU28.09.2010
BG03.07.2013
CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
MK03.07.2013
MT03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
SM03.07.2013
TR03.07.2013
IE28.09.2013
LU28.09.2013
BE30.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2015/32]CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
MK03.07.2013
MT03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
SM03.07.2013
TR03.07.2013
IE28.09.2013
BE30.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2015/24]CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
SM03.07.2013
IE28.09.2013
BE30.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/34]CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
IE28.09.2013
BE30.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/33]CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
IE28.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/24]CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
IT03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/23]CY03.07.2013
CZ03.07.2013
DK03.07.2013
EE03.07.2013
FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
SK03.07.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/22]CY03.07.2013
DK03.07.2013
FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
RO03.07.2013
SE03.07.2013
SI03.07.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/21]CY03.07.2013
DK03.07.2013
FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
SE03.07.2013
SI03.07.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/20]CY03.07.2013
FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
MC03.07.2013
NL03.07.2013
PL03.07.2013
SE03.07.2013
SI03.07.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/18]CY03.07.2013
FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
NL03.07.2013
PL03.07.2013
SE03.07.2013
SI03.07.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/14]FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
NL03.07.2013
PL03.07.2013
SE03.07.2013
SI03.07.2013
CY04.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/12]FI03.07.2013
HR03.07.2013
LT03.07.2013
LV03.07.2013
PL03.07.2013
SE03.07.2013
SI03.07.2013
CY04.09.2013
NO03.10.2013
GR04.10.2013
ES14.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/11]FI03.07.2013
HR03.07.2013
LT03.07.2013
PL03.07.2013
SE03.07.2013
SI03.07.2013
CY04.09.2013
NO03.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/10]HR03.07.2013
LT03.07.2013
SE03.07.2013
SI03.07.2013
CY04.09.2013
NO03.10.2013
IS03.11.2013
PT04.11.2013
Former [2014/09]HR03.07.2013
LT03.07.2013
SE03.07.2013
SI03.07.2013
NO03.10.2013
PT04.11.2013
Former [2014/08]LT03.07.2013
SI03.07.2013
NO03.10.2013
PT04.11.2013
Former [2014/07]SI03.07.2013
NO03.10.2013
Former [2013/49]SI03.07.2013
Documents cited:Search[A]WO0240695  (RNA INC [KR], et al) [A] 1-18;
 [A]KR20020075068  (KIM JUNG BAE [KR]) [A] 1-18;
 [A]  - FABER K N ET AL, "Foreign gene expression in Hansenula polymorpha. A system for the synthesis of small functional peptides", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, (1996), vol. 45, no. 1-2, ISSN 0175-7598, pages 72 - 79, XP009160678 [A] 1-18

DOI:   http://dx.doi.org/10.1007/s002530050651
 [A]  - LEE JUNG-LIM ET AL, "Functional assembly of recombinant human ferritin subunits in Pichia pastoris", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, (200710), vol. 17, no. 10, pages 1695 - 1699 URL, XP002678808 [A] 1-18
 [A]  - SEO H -Y ET AL, "Enhanced expression and functional characterization of the human ferritin H- and L-chain genes in Saccharomyces cerevisiae.", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, (200311), vol. 63, no. 1, ISSN 0175-7598, pages 57 - 63, XP002678809 [A] 1-18

DOI:   http://dx.doi.org/10.1007/S00253-003-1350-3
 [A]  - VAD R ET AL, "Engineering of a Pichia pastoris expression system for secretion of high amounts of intact human parathyroid hormone", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 116, no. 3, ISSN 0168-1656, (20050330), pages 251 - 260, (20050330), XP027663548 [A] 1-18
 [T]  - EILERT EVA ET AL, "The use of highly expressed FTH1 as carrier protein for cytosolic targeting in Hansenula polymorpha", JOURNAL OF BIOTECHNOLOGY, (201206), vol. 159, no. 3, pages 172 - 176 URL, XP002678810

DOI:   http://dx.doi.org/10.1016/J.JBIOTEC.2011.12.014
by applicant   - P. SANTAMBROGIO; S. LEVI; A. COZZI; E. ROVIDAJ; A. ALBERTINI; P. AROS, "Production and Characterization of Recombinant Heteropolymers of Human Ferritin H and L Chains", J. BIOL. CHEM., (1993), vol. 268, pages 12744 - 12783
    - Y. M. SHIN; T. H. KWON; K. S. KIM; K. S. CHAE; D. H. KIM; M.S. YANG, "Enhanced Iron Uptake of Saccharomyces cerevisiae by Heterologous Expression of a Tadpole Ferritin Gene", APPL. ENVIRON. MICROBIOL., (2001), vol. 67, pages 1280 - 1283
    - J. L. LEE; H. S. SONG; H. J. KIM; J. H. PARK; D. K. CHUNG; C. S. PARK; D. JEUNG; H. Y. KIM, "Functional expression and production of human H-ferritin in Pichia pastoris", BIOTECHNOL. LETT., (2003), vol. 25, pages 1019 - 1023
    - MEYER A. F. ET AL., "An expression system matures: a highly efficient and cost effective process for phytase production by recombinant strains of Hansenula polymorpha", BIOTECHNOL. BIOENG., (1999), vol. 63, pages 373 - 381
    - KIM ET AL., "Expression of Heter opolymeric Ferritin Improves Iron Storage in Saccharomyces cerevisiae", APPL. ENVIRON. MICROBIOL., (2003), vol. 69, pages 1999 - 2005
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.