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Extract from the Register of European Patents

EP About this file: EP2399613

EP2399613 - Fractionation of plasma using caprylic acid [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.11.2012
Database last updated on 03.10.2024
Most recent event   Tooltip16.11.2012Application deemed to be withdrawnpublished on 19.12.2012  [2012/51]
Applicant(s)For all designated states
Research Foundation For Medical Devices
Rue Faucigny 5
1700 Fribourg / CH
[2011/52]
Inventor(s)01 / Burnouf, Thierry
86 Rue Deleval
59249, AUBERS / FR
02 / El-Ekiaby, Magdy
64, Street 14, Maadi
CAIRO / EG
03 / Goubran, Hadi Alphonse
73, Road 9 Maadi
11431, CAIRO / EG
04 / Radosevich, Miryana
86 rue Deleval
59249, AUBERS / FR
 [2011/52]
Representative(s)Plasseraud IP
104 Rue de Richelieu
CS92104
75080 Paris Cedex 02 / FR
[N/P]
Former [2011/52]Cabinet Plasseraud
52, rue de la Victoire
75440 Paris Cedex 09 / FR
Application number, filing date10305669.322.06.2010
[2011/52]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2399613
Date:28.12.2011
Language:EN
[2011/52]
Search report(s)(Supplementary) European search report - dispatched on:EP22.12.2010
ClassificationIPC:A61L2/00, C07K16/06
[2011/52]
CPC:
C07K16/065 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/52]
Extension statesBANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:Plasmafraktionierung mittels Verwendung der Caprylsäure[2011/52]
English:Fractionation of plasma using caprylic acid[2011/52]
French:Fractionnement plasmatique par l'acide caprylique[2011/52]
Examination procedure29.06.2012Application deemed to be withdrawn, date of legal effect  [2012/51]
06.08.2012Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2012/51]
Fees paidRenewal fee
17.04.2012Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[I]WO2005073252  (SUOMEN PUNAINEN RISTI VERIPALV [FI], et al) [I] 1-8 * the whole document *;
 [I]WO2005082937  (OCTAPHARMA AG [CH], et al) [I] 1-8 * the whole document *;
 [I]  - HABEEB A F S A AND FRANCIS R D, "Preparation of human immunoglobuilin by caprylic acid precipitation", PREPARATIVE BIOCHEMISTRY, NEW YORK, NY, US, (19840101), vol. 14, no. 1, pages 1 - 17, XP002078264 [I] 1-8 * the whole document *
 [I]  - ROJAS G ET AL, "Caprylic acid fractionation of hyperimmune horse plasma: Description of a simple procedure for antivenom production", TOXICON, ELMSFORD, NY, US, vol. 32, no. 3, doi:10.1016/0041-0101(94)90087-6, ISSN 0041-0101, (19940301), pages 351 - 363, (19940301), XP023724234 [I] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1016/0041-0101(94)90087-6
 [I]  - RADOSEVICH M ET AL, "Intravenous immunoglobulin G: Trends in production methods, quality control and quality assurance", VOX SANGUINIS 2010 BLACKWELL PUBLISHING LTD GBR LNKD- DOI:10.1111/J.1423-0410.2009.01226.X, (201001), vol. 98, no. 1, ISSN 0042-9007, pages 12 - 28, XP009141581 [I] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1423-0410.2009.01226.x
 [I]  - STUCKI M ET AL, "Investigations of prion and virus safety of a new liquid IVIG product", BIOLOGICALS, ACADEMIC PRESS LTD., LONDON, GB, vol. 36, no. 4, doi:10.1016/J.BIOLOGICALS.2008.01.004, ISSN 1045-1056, (20080701), pages 239 - 247, (20080312), XP022795227 [I] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.biologicals.2008.01.004
 [I]  - BURNOUF ET AL, "Modern Plasma Fractionation", TRANSFUSION MEDICINE REVIEWS, GRUNE AND STRATTON, ORLANDO, FL, US, (20070328), vol. 21, no. 2, doi:10.1016/J.TMRV.2006.11.001, ISSN 0887-7963, pages 101 - 117, XP022020853 [I] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.tmrv.2006.11.001
 [I]  - BUCHACHER ANDREA ET AL, "Purification of intravenous immunoglobulin G from human plasma - aspects of yield and virus safety", BIOTECHNOLOGY JOURNAL, (200602), vol. 1, no. 2, ISSN 1860-6768, pages 148 - 163, XP009141576 [I] 1-8 * the whole document *
 [I]  - LEBING W ET AL, "PROPERTIES OF A NEW INTRAVENOUS IMMUNOGLOBULIN (IGIV-C, 10%) PRODUCED BY VIRUS INACTIVATION WITH CAPRYLATE AND COLUMN CHROMATOGRAPHY", VOX SANGUINIS, S. KARGER AG, BASEL, CH, (20030401), vol. 84, no. 3, doi:10.1046/J.1423-0410.2003.00285.X, ISSN 0042-9007, pages 193 - 201, XP001197282 [I] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1046/j.1423-0410.2003.00285.x
 [I]  - DICHTELMUELLER H ET AL, "INACTIVATION OF LIPID ENVELOPED VIRUSES BY OCTANOIC ACID TREATMENT OF IMMUNOGLOBULIN SOLUTION", BIOLOGICALS, ACADEMIC PRESS LTD., LONDON, GB, (20020601), vol. 30, no. 2, doi:10.1006/BIOL.2002.0332, ISSN 1045-1056, pages 135 - 142, XP001149476 [I] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1006/biol.2002.0332
 [XA]  - Biotest (UK) Ltd, "Zutectra", (20091130), pages 1 - 5, URL: http://www.medicines.org.uk/EMC/medicine/23193/SPC/Zutectra/, (20101208), XP002613316 [X] 8 * the whole document * [A] 1-7
by applicantUS4481189
 US4540573
 WO2006082115
    - BURNOUF; RADOSEVICH, BLOOD REV, (2000), vol. 14, pages 94 - 110
    - TOUBI E; ETZIONI A, "Intravenous immunoglobulin in immunodeficiency states: state of the art", CLIN REV ALLERGY IMMUNOL., (2005), vol. 29, pages 167 - 72
    - KIVITY S; KATZ U; DANIEL N; NUSSINOVITCH U; PAPAGEORGIOU N; SHOENFELD Y, "Evidence for the use of intravenous immunoglobulins--a review of the literature", CLIN REV ALLERGY IMMUNOL., (2010), vol. 38, pages 201 - 69
    - BURNOUF T, "Modem plasma fractionation", TRANSFUS MED REV., (2007), vol. 21, pages 101 - 17
    - BURNOUF T, "Plasma fractionation in the world: Current status", TRANSFUS CLIN BIOL., (2007), vol. 14, pages 41 - 50
    - DODEL R; NEFF F; NOELKER C; PUL R; DU YS; BACHER M; OERTEL W, "Intravenous Immunoglobulins as a Treatment for Alzheimer's Disease Rationale and Current Evidence", DRUGS, (2010), vol. 70, pages 513 - 28
    - BURNOUF T, "Plasma fractionation in the world: Current status.", TRANSFUS CLIN BIOL., (2007), vol. 14, pages 41 - 50
    - HABEEB AF; FRANCIS RD, "Preparation of human immunoglobulin by caprylic acid precipitation", PREP BIOCHEM., (1984), vol. 14, pages 1 - 17
    - STEINBUCH M; AUDRAN R, "Isolation of IgG immunoglobulin from human plasma using caprylic acid", REV FR ETUD CLIN BIOL, (1969), vol. 14, pages 1054 - 8
    - PARKKINEN J; RAHOLA A; VON BONSDORFF L; TOLO H; TORMA E, "A modified caprylic acid method for manufacturing immunoglobulin G from human plasma with high yield and efficient virus clearance", VOX SANG, (2006), vol. 90, pages 97 - 104
    - LEBING W; REMINGTON KM; SCHREINER C; PAUL HI, "Properties of a new intravenous immunoglobulin (IGIV-C, 10%) produced by virus inactivation with caprylate and column chromatography", VOX SANG., (2003), vol. 84, pages 193 - 201
    - DICHTELMULLER H; RUDNICK D; KLOFT M, "Inactivation of lipid enveloped viruses by octanoic acid treatment of immunoglobulin solution", BIOLOGICALS, (2002), vol. 30, pages 135 - 42
    - ROJAS G; JIMENEZ JM; GUTIERREZ JM, "Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production", TOXICON, (1994), vol. 32, pages 351 - 63
    - OTERO-PATINO RET, "A randomized, blinded, comparative trial of one pepsin-digested and two whole IgG antivenoms for Bothrops snake bites in Uraba, Colombia. The Regional Group on Antivenom Therapy Research (REGATHER)", AM J TROP MED HYG., (1998), vol. 58, pages 183 - 9
    - OTERO R ET AL., "A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms", TOXICON, (1999), vol. 37, pages 895 - 908
    - BURNOUF T; RADOSEVICH M, "Reducing the risk of infection from plasma products: Specific preventative strategies", BLOOD REV., (2000), vol. 14, pages 94 - 110
    - EL EKIABY M; LELIE N; ALLAIN JP, "Nucleic acid testing (NAT) in high prevalence-low resource settings", BIOLOGICALS, (2010), vol. 38, pages 59 - 64
    - BURNOUF T, "Radosevich M: Reducing the risk of infection from plasma products: Specific preventative strategies", BLOOD REV., (2000), vol. 14, pages 94 - 110
    - BURNOUF T; RADOSEVICH M, "Nanofiltration of plasma-derived biopharmaceutical products", HAEMOPHILIA, (2003), vol. 9, pages 24 - 37
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.