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Extract from the Register of European Patents

EP About this file: EP2418491

EP2418491 - Method for the diagnosis of dry eye and blepharitis [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  04.01.2013
Database last updated on 24.04.2024
Most recent event   Tooltip04.01.2013Application deemed to be withdrawnpublished on 06.02.2013  [2013/06]
Applicant(s)For all designated states
Bioftalmik, S.L.
Parque Technológico de Vizcaya Edificio 800, 2º Planta
48160 Derio (Vizcaya) / ES
[2012/07]
Inventor(s)01 / Soria Esponera, Javier
BIOFTALMIK S.L.
Parque Tecnológico de Vizcaya
Edificio 800, 2a Planta
48160 Derio (Bizkaia) / ES
02 / Suarez Cortés, Tatiana
BIOFTALMIK S.L.
Parque Tecnológico de Vizcaya
Edificio 800, 2a Planta
48160 Derio (Bizkaia) / ES
03 / Gonzalez Fernandez, Nerea
BIOFTALMIK S.L.
Parque Tecnológico de Vizcaya
Edificio 800, 2a Planta
48160 Derio (Bizkaia) / ES
04 / Acera Osa, Arantxa
BIOFTALMIK S.L.
Parque Tecnológico de Vizcaya
Edificio 800, 2a Planta
48160 Derio (Bizkaia) / ES
 [2012/07]
Representative(s)ABG Intellectual Property Law, S.L.
Avenida de Burgos, 16D
Edificio Euromor
28036 Madrid / ES
[N/P]
Former [2012/07]ABG Patentes, S.L.
Avenida de Burgos 16D Edificio Euromor
28036 Madrid / ES
Application number, filing date10382229.210.08.2010
[2012/07]
Filing languageES
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2418491
Date:15.02.2012
Language:EN
[2012/07]
Search report(s)(Supplementary) European search report - dispatched on:EP19.04.2011
ClassificationIPC:G01N33/68
[2012/07]
CPC:
G01N33/6893 (EP,US); G01N2800/101 (EP,US); G01N2800/16 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/07]
Extension statesBANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:Verfahren zur Diagnose von Xerophthalmie und Blepharitis[2012/07]
English:Method for the diagnosis of dry eye and blepharitis[2012/07]
French:Procédé pour le diagnostic de la sécheresse oculaire et de la blépharite[2012/07]
Examination procedure17.08.2012Application deemed to be withdrawn, date of legal effect  [2013/06]
21.09.2012Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2013/06]
Fees paidPenalty fee
Additional fee for renewal fee
31.08.201203   M06   Not yet paid
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Documents cited:Search[A]KR20060077374  (UNIV KOREA IND & ACAD COOP [KR]) [A] 3,4,9-12 * the whole document * * See in particular: Title and abstract; Examples 1-4. Fig. 1. * * This document is relevant for originally identified invention 10. *;
 [A]US2009258828  (BEUERMAN ROGER [SG], et al) [A] 1,2,9-12 * the whole document * * In particular: Fig. 1-8; paragraphs 1, 2, 16, 77-100 (examples 1-10). * * This document is relevant for originally identified Invention 1. *;
 [X]  - NICHOLS JASON J ET AL, "Mass spectrometry-based proteomic analyses in contact lens-related dry eye.", CORNEA DEC 2009 LNKD- PUBMED:19770725, (200912), vol. 28, no. 10, ISSN 1536-4798, pages 1109 - 1117, XP008129932 [X] 1,2,9-12 * the whole document * * In particular: Title; Abstract; Methods section; Discussion, 3rd paragraph; Table 1. * * This document is relevant for originally identified Invention 1. *
 [X]  - VERSURA P ET AL, "Proteomic analysis in hyperevaporative dry eye patients", RIVISTA ITALIANA DELLA MEDICINA DI LABORATORIO 2009 SIMEL SOCIETA ITALIANA DI MEDICINA DI LABORATORIO ITA, (2009), vol. 5, no. 4, ISSN 1825-859X, pages 290 - 297, XP002612107 [X] 1,2,9-12 * the whole document * * In particular: Title; Abstract (Riassunto); Materiali e metodi section; Figura 2-3. * * This document is relevant for originally identified Invention 1. *
 [X]  - VERSURA P ET AL, "Tear proteomics in evaporative dry eye disease.", EYE (LONDON, ENGLAND) AUG 2010 LNKD- PUBMED:20150925, (20100212), vol. 24, no. 8, ISSN 1476-5454, pages 1396 - 1402, XP008129926 [X] 1,2,9-12 * the whole document * * In particular: Title; Abstract; Materials and methods section; Table 3; Figure 1. * * This document is relevant for originally identified Invention 1. *
 [X]  - KOO BON-SUK ET AL, "Comparative analysis of the tear protein expression in blepharitis patients using two-dimensional electrophoresis", JOURNAL OF PROTEOME RESEARCH, (200505), vol. 4, no. 3, ISSN 1535-3893, pages 719 - 724, XP002631281 [X] 1,2,9-12 * the whole document * * In particular: Title; Abstract; Materials and methods section; Table 1. * * This document is relevant for originally identified Invention 3 (Cystatin S, aka cystain SAIII) as well as for invention 10. *

DOI:   http://dx.doi.org/10.1021/PR0498133
 [X]  - BALDINI ET AL, "Proteomic analysis of the saliva: A clue for understanding primary from secondary Sjogren's syndrome?", AUTOIMMUNITY REVIEWS, ELSEVIER, AMSTERDAM, NL, (20080109), vol. 7, no. 3, doi:10.1016/J.AUTREV.2007.11.002, ISSN 1568-9972, pages 185 - 191, XP022413397 [X] 1,2,9-12 * the whole document * * In particular: Title; Abstract; p. 188, col. 1-2, bridging paragraph; p. 189, table 2. * * This document is relevant for inventions 3 (cystain S) for originally identified invention 4 (cystatin N, aka cystatin SN). *

DOI:   http://dx.doi.org/10.1016/j.autrev.2007.11.002
 [X]  - FERRACCIOLI G ET AL, "Proteomic approaches to Sjogren's syndrome: A clue to interpret the pathophysiology and organ involvement of the disease", AUTOIMMUNITY REVIEWS, ELSEVIER, AMSTERDAM, NL, vol. 9, no. 9, ISSN 1568-9972, (20100701), pages 622 - 626, (20100701), XP027130642 [X] 1,2,9-12 * the whole document * * In particular: Title; Abstract; Table 1. * * This document is relevant for originally identified invention 4 (cystatin N, aka cystatin SN). *
 [X]  - GIUSTI LAURA ET AL, "Proteome analysis of whole saliva: a new tool for rheumatic diseases--the example of Sjögren's syndrome.", PROTEOMICS MAY 2007 LNKD- PUBMED:17436266, (200705), vol. 7, no. 10, ISSN 1615-9853, pages 1634 - 1643, XP002631282 [X] 1,2,9-12 * the whole document * * In particular: Title; abstract; Material and methods section; Tables 2-4; Discussion, paragraphs 1 and 3. * * This document is relevant for originally identified inventions 3 and 4. *

DOI:   http://dx.doi.org/10.1002/PMIC.200600783
 [X]  - STEINFELD SERGE ET AL, "Big prolactin 60 kDa is overexpressed in salivary glandular epithelial cells from patients with Sjogren's syndrome", LABORATORY INVESTIGATION, (200002), vol. 80, no. 2, ISSN 0023-6837, pages 239 - 247, XP002631283 [X] 1,2,9-12 * the whole document * * In particular: Title; Summary; p. 240, col. 1, 1st paragraph; Fig. 1; * * This document is relevant for originally identified invention 6 (S100A6). *
 [X]  - YUAN YUNFENG ET AL, "Reduction of GSTP1 expression by DNA methylation correlates with clinicopathological features in pituitary adenomas", MODERN PATHOLOGY, (200807), vol. 21, no. 7, ISSN 0893-3952, pages 856 - 865, XP002631284 [X] 9-12 * the whole document * * In particular: Title; Abstract; Materials and methods section. * * This document is relevant for originally identified invention 7 (GSTP1). *

DOI:   http://dx.doi.org/10.1038/MODPATHOL.2008.60
 [A]  - MENEGAY MICHELLE ET AL, "Proteomic analysis of climatic keratopathy droplets.", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE JUL 2008 LNKD- PUBMED:18378572, (200807), vol. 49, no. 7, ISSN 1552-5783, pages 2829 - 2837, XP002631285 [A] 1,2,9-12 * the whole document * * In particular: Title; Abstract; Table 1. * * This document is relevant for originally identified invention 8 (Annexin I). *

DOI:   http://dx.doi.org/10.1167/IOVS.07-1438
 [X]  - PICKLES KIRSTIE J ET AL, "Expression of annexin-1 in equine leucocytes and the effects of the N-terminal annexin-1 peptide, Ac2-26, on equine neutrophil superoxide production", VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, (201006), vol. 135, no. 3-4, ISSN 0165-2427, pages 226 - 233, XP002631286 [X] 9-12 * the whole document * * In particular: Title; Abstract; Materials and methods section. * * This document is relevant for originally identified invention 8 (annexin I). *

DOI:   http://dx.doi.org/10.1016/J.VETIMM.2009.12.002
 [X]  - MECHTHILD STOECKELHUBER ET AL, "Immunohistochemical analysis of secretoglobin SCGB 2A1 expression in human ocular glands and tissues", HISTOCHEMISTRY AND CELL BIOLOGY, SPRINGER, BERLIN, DE, (20060104), vol. 126, no. 1, doi:10.1007/S00418-005-0137-2, ISSN 1432-119X, pages 103 - 109, XP019427003 [X] 9-12 * the whole document * * In particular: Title; Abstract; Materials and methods section. * * This document is relevant for originally identified invention 10. *

DOI:   http://dx.doi.org/10.1007/s00418-005-0137-2
by applicantUS4774339
 US5268486
    - THE OCULAR SURFACE, (200704), vol. 5, no. 2, pages 69 - 202
    - LEMP MA, "Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes", CLAO J., (1995), vol. 21, pages 221 - 32
    - ALTSCHUL, S. ET AL., BLASTManual, NCBI NLM NIH
    - ALTSCHUL, S. ET AL., J. MOL. BIOL., (1990), vol. 215, pages 403 - 410
    - MUJUMDAR, R. B. ET AL., CYTOMETRY, (1989), vol. 10, pages 11 - 19
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.