EP2396331 - FUSED PYRIMIDINES AS AKT INHIBITORS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 22.08.2014 Database last updated on 03.09.2024 | Most recent event Tooltip | 22.06.2018 | Lapse of the patent in a contracting state New state(s): MK | published on 25.07.2018 [2018/30] | Applicant(s) | For all designated states Bayer Intellectual Property GmbH Alfred-Nobel-Strasse 10 40789 Monheim / DE | [2012/39] |
Former [2011/51] | For all designated states Bayer Pharma Aktiengesellschaft Müllerstrasse 178 13353 Berlin / DE | Inventor(s) | 01 /
VENNEMANN, Matthias Leinerstrasse 20 78462 Konstanz / DE | 02 /
BÄR, Thomas Berggässle 5 78479 Reichenau / DE | 03 /
MAIER, Thomas Panoramaweg 31 78333 Stockach / DE | 04 /
HÖLDER, Swen 49E Crystal Palace Park Road London SE26 6UR / GB | 05 /
BENEKE, Gerrit Elisabeth-Mühlenweg-Strasse 17 78476 Allensbach / DE | 06 /
DEHMEL, Florian Am Kupferofen 3 52066 Aachen / DE | 07 /
ZÜLCH, Armin Strahlenberger Str. 50 69198 Schriesheim / DE | 08 /
STRUB, Andreas Im Grund 15f 82152 Planegg / DE | 09 /
BECKERS, Thomas Tivolistr. 5 79104 Freiburg i.Br. / DE | 10 /
INCE, Stuart Katteweg 27a 14129 Berlin / DE | 11 /
REHWINKEL, Hartmut Blücherstrasse 13 10961 Berlin / DE | 12 /
LIU, Ningshu Limonenstr. 28 12203 Berlin / DE | 13 /
BÖMER, Ulf Leipziger Str. 49 16548 Glienicke/Nordbahn / DE | [2011/51] | Representative(s) | BIP Patents c/o Bayer Intellectual Property GmbH Alfred-Nobel-Straße 50 40789 Monheim am Rhein / DE | [N/P] |
Former [2013/42] | BIP Patents c/o Bayer Intellectual Property GmbH Creative Campus Monheim Alfred-Nobel-Straße 10 40789 Monheim / DE | ||
Former [2013/01] | BIP Patents Creative Campus Monheim Alfred-Nobel-Straße 10 40789 Monheim / DE | ||
Former [2012/39] | Bayer Intellectual Property GmbH Creative Campus Monheim Alfred-Nobel-Straße 10 40789 Monheim / DE | ||
Former [2011/51] | (deleted) | Application number, filing date | 10703022.3 | 05.02.2010 | WO2010EP00717 | Priority number, date | EP20090152805 | 13.02.2009 Original published format: EP 09152805 | [2011/51] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2010091824 | Date: | 19.08.2010 | Language: | EN | [2010/33] | Type: | A1 Application with search report | No.: | EP2396331 | Date: | 21.12.2011 | Language: | EN | The application published by WIPO in one of the EPO official languages on 19.08.2010 takes the place of the publication of the European patent application. | [2011/51] | Type: | B1 Patent specification | No.: | EP2396331 | Date: | 16.10.2013 | Language: | EN | [2013/42] | Search report(s) | International search report - published on: | EP | 19.08.2010 | Classification | IPC: | C07D487/04, A61P35/00, A61K31/517 | [2011/51] | CPC: |
C07D487/04 (EP,US);
A61K31/519 (US);
A61K45/06 (US);
A61P35/00 (EP)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2011/51] | Extension states | AL | Not yet paid | BA | Not yet paid | RS | Not yet paid | Title | German: | KONDENSIERTE PYRIMIDINE ALS AKT-INHIBITOREN | [2011/51] | English: | FUSED PYRIMIDINES AS AKT INHIBITORS | [2011/51] | French: | PYRIMIDINES CONDENSÉES EN TANT QU'INHIBITEURS D'AKT | [2011/51] | Entry into regional phase | 13.09.2011 | National basic fee paid | 13.09.2011 | Designation fee(s) paid | 13.09.2011 | Examination fee paid | Examination procedure | 13.09.2011 | Examination requested [2011/51] | 02.05.2013 | Communication of intention to grant the patent | 03.09.2013 | Fee for grant paid | 03.09.2013 | Fee for publishing/printing paid | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 02.05.2013 | Opposition(s) | 17.07.2014 | No opposition filed within time limit [2014/39] | Fees paid | Renewal fee | 15.02.2012 | Renewal fee patent year 03 | 28.02.2013 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 05.02.2010 | AT | 16.10.2013 | BE | 16.10.2013 | BG | 16.10.2013 | CY | 16.10.2013 | CZ | 16.10.2013 | DK | 16.10.2013 | EE | 16.10.2013 | FI | 16.10.2013 | HR | 16.10.2013 | LT | 16.10.2013 | LV | 16.10.2013 | MC | 16.10.2013 | MK | 16.10.2013 | MT | 16.10.2013 | NL | 16.10.2013 | PL | 16.10.2013 | RO | 16.10.2013 | SE | 16.10.2013 | SI | 16.10.2013 | SK | 16.10.2013 | SM | 16.10.2013 | TR | 16.10.2013 | NO | 16.01.2014 | GR | 17.01.2014 | IE | 05.02.2014 | LU | 05.02.2014 | IS | 16.02.2014 | PT | 17.02.2014 | CH | 28.02.2014 | LI | 28.02.2014 | [2018/30] |
Former [2016/33] | HU | 05.02.2010 | |
AT | 16.10.2013 | ||
BE | 16.10.2013 | ||
BG | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
MT | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SI | 16.10.2013 | ||
SK | 16.10.2013 | ||
SM | 16.10.2013 | ||
TR | 16.10.2013 | ||
NO | 16.01.2014 | ||
GR | 17.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2016/32] | HU | 05.02.2010 | |
AT | 16.10.2013 | ||
BE | 16.10.2013 | ||
BG | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
MT | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SI | 16.10.2013 | ||
SK | 16.10.2013 | ||
SM | 16.10.2013 | ||
NO | 16.01.2014 | ||
GR | 17.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2016/28] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
BG | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
MT | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SI | 16.10.2013 | ||
SK | 16.10.2013 | ||
SM | 16.10.2013 | ||
NO | 16.01.2014 | ||
GR | 17.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2016/22] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
MT | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SI | 16.10.2013 | ||
SK | 16.10.2013 | ||
SM | 16.10.2013 | ||
NO | 16.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2016/12] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
MT | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SI | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2015/14] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SI | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2015/07] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
IE | 05.02.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2014/46] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
CH | 28.02.2014 | ||
LI | 28.02.2014 | ||
Former [2014/44] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
MC | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
LU | 05.02.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
Former [2014/41] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
DK | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
Former [2014/37] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
CZ | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
NL | 16.10.2013 | ||
PL | 16.10.2013 | ||
RO | 16.10.2013 | ||
SE | 16.10.2013 | ||
SK | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
Former [2014/36] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
EE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
Former [2014/28] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
PT | 17.02.2014 | ||
Former [2014/26] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
CY | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
Former [2014/25] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
LV | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
Former [2014/24] | AT | 16.10.2013 | |
BE | 16.10.2013 | ||
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
Former [2014/23] | BE | 16.10.2013 | |
FI | 16.10.2013 | ||
HR | 16.10.2013 | ||
LT | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
IS | 16.02.2014 | ||
Former [2014/22] | FI | 16.10.2013 | |
LT | 16.10.2013 | ||
NL | 16.10.2013 | ||
SE | 16.10.2013 | ||
NO | 16.01.2014 | ||
Former [2014/20] | LT | 16.10.2013 | |
NO | 16.01.2014 | Cited in | International search | [A]WO03089434 (CELLULAR GENOMICS INC [US]) [A] 1-16 * page 1, paragraph 1 ** claim 1 *; | [A]WO2004096131 (MERCK & CO INC [US], et al) [A] 1-16 * page 1, paragraph 1 * * claim 1 *; | [A]WO2006065601 (MERCK & CO INC [US], et al) [A] 1-16 * page 1, paragraph 1 * * claim 1 *; | [A] - WU Z ET AL, "Rapid assembly of diverse and potent allosteric Akt inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB LNKD- DOI:10.1016/J.BMCL.2007.10.023, vol. 18, no. 6, ISSN 0960-894X, (20080315), pages 2211 - 2214, (20071017), XP025695048 [A] 1-16 * the whole document * DOI: http://dx.doi.org/10.1016/j.bmcl.2007.10.023 | by applicant | WO2004096131 | WO2005100344 | WO2006036395 | WO2006065601 | WO2006091395 | WO2006135627 | - Y. LI ET AL., BIOORG. MED. CHEM. LETT., (2009), vol. 19, pages 834 - 836 | - GARCIA-ECHEVERRIA ET AL., ONCOGENE, (2008), vol. 27, pages 551 - 4526 | - O'BRIEN ET AL., EUR J BIOCHEM, (2000), vol. 267, pages 5421 - 5426 |