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Extract from the Register of European Patents

EP About this file: EP2416774

EP2416774 - TREATMENT REGIMEN UTILIZING NERATINIB FOR BREAST CANCER [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  10.12.2021
Database last updated on 03.04.2025
FormerThe patent has been granted
Status updated on  07.01.2018
Most recent event   Tooltip10.12.2021Revocation of patentpublished on 12.01.2022  [2022/02]
10.12.2021New entry: Despatch of communication that patent is revoked 
Applicant(s)For all designated states
Wyeth LLC
235 East 42nd Street
New York, NY 10017 / US
[2014/20]
Former [2012/07]For all designated states
Wyeth LLC
Five Giralda Farms
Madison, NJ 07940 / US
Inventor(s)01 / BERKENBLIT, Anna
60 Hoover Road
Needham Massachusetts 02494 / US
02 / BINLICH, Florence
35 Avenue Thierry
F-92410 Ville D'Avray / FR
03 / GOSS, Paul
904 Washington Street
Wellesley Massachusetts 02482 / US
 [2012/07]
Representative(s)Jones Day
Rechtsanwälte, Attorneys-at-Law, Patentanwälte
Prinzregentenstrasse 11
80538 München / DE
[N/P]
Former [2012/07]Weber, Martin
Jones Day
Prinzregentenstraße 11
80538 München / DE
Application number, filing date10722215.024.03.2010
[2015/45]
WO2010US28448
Priority number, dateUS20090166796P06.04.2009         Original published format: US 166796 P
[2012/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010117633
Date:14.10.2010
Language:EN
[2010/41]
Type: A1 Application with search report 
No.:EP2416774
Date:15.02.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 14.10.2010 takes the place of the publication of the European patent application.
[2012/07]
Type: B1 Patent specification 
No.:EP2416774
Date:04.11.2015
Language:EN
[2015/45]
Search report(s)International search report - published on:EP14.10.2010
ClassificationIPC:A61K31/4709, A61P35/00
[2012/07]
CPC:
A61K31/4706 (EP,CN,IL,US); A61K31/4709 (EP,IL,KR,RU,US); A61K39/39558 (EP,CN,IL,KR,US);
A61K45/06 (EP,CN,IL,KR,US); A61P15/00 (EP,IL); A61P19/10 (EP,IL,KR);
A61P35/00 (EP,IL,KR,RU); A61P43/00 (EP,IL); A61K2039/505 (IL,KR);
A61K2300/00 (IL,KR) (-)
C-Set:
A61K31/4706, A61K2300/00 (CN);
A61K31/4709, A61K2300/00 (EP,US);
A61K39/39558, A61K2300/00 (US,CN,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/07]
Extension statesALNot yet paid
BANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:BEHANDLUNGSSCHEMA MIT NERATINIB GEGEN BRUSTKREBS[2012/07]
English:TREATMENT REGIMEN UTILIZING NERATINIB FOR BREAST CANCER[2012/07]
French:RÉGIME DE TRAITEMENT À L'AIDE DE NÉRATINIB POUR UN CANCER DU SEIN[2012/07]
Entry into regional phase07.11.2011National basic fee paid 
07.11.2011Designation fee(s) paid 
07.11.2011Examination fee paid 
Examination procedure07.11.2011Examination requested  [2012/07]
20.07.2012Amendment by applicant (claims and/or description)
11.06.2013Despatch of a communication from the examining division (Time limit: M06)
11.12.2013Reply to a communication from the examining division
17.04.2015Cancellation of oral proceeding that was planned for 23.04.2015
23.04.2015Date of oral proceedings (cancelled)
05.06.2015Communication of intention to grant the patent
22.09.2015Fee for grant paid
22.09.2015Fee for publishing/printing paid
22.09.2015Receipt of the translation of the claim(s)
Divisional application(s)EP15188350.1  / EP3000467
EP23157078.9
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.06.2013
Opposition(s)Opponent(s)01  03.08.2016  08.08.2016  ADMISSIBLE
Hexal AG
Industriestrasse 25
83607 Holzkirchen / DE
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 [N/P]
Former [2018/52]
Opponent(s)01  03.08.2016  08.08.2016  ADMISSIBLE
Hexal AG
Industriestrasse 25
83607 Holzkirchen / DE
Opponent's representative
Elkington & Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
Former [2016/38]
Opponent(s)01  03.08.2016  08.08.2016  ADMISSIBLE
Hexal AG
Industriestrasse 25
83607 Holzkirchen / DE
Opponent's representative
Mullen, Lee Bryan
Elkington and Fife LLP
Patens Department
3-4 Holborn Circus
London EC1N 2HA / GB
Former [2016/37]
Opponent(s)01  03.08.2016  08.08.2016  ADMISSIBLE
Hexal AG
Industriestrasse 25
83607 Holzkirchen / DE
Opponent's representative
Mullen, Lee Bryan
Elkington and Fife LLP
Thavies Inn House
3-4 Holborn Circus
London EC1N 2HA / GB
deletedDeletion: Legal effect of rejection of opposition [ N /P ]
08.09.2016Invitation to proprietor to file observations on the notice of opposition
22.12.2016Reply of patent proprietor to notice(s) of opposition
08.12.2017Date of oral proceedings
08.01.2018Despatch of minutes of oral proceedings
08.01.2018Date of despatch of rejection of opposition
02.09.2021Legal effect of revocation of patent [2022/02]
19.10.2021Despatch of communication that the patent will be revoked
Appeal following opposition16.03.2018Appeal received No.  T0728/18
15.05.2018Statement of grounds filed
02.09.2021Result of appeal procedure: revocation of the patent
19.10.2021Despatch of the decision of the Board of Appeal
02.09.2021Date of oral proceedings
Fees paidRenewal fee
14.03.2012Renewal fee patent year 03
11.03.2013Renewal fee patent year 04
12.03.2014Renewal fee patent year 05
10.03.2015Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU24.03.2010
AT04.11.2015
BE04.11.2015
BG04.11.2015
CY04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
MK04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
TR04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
IE24.03.2016
LU24.03.2016
CH31.03.2016
LI31.03.2016
MT31.03.2016
[2018/38]
Former [2018/31]HU24.03.2010
AT04.11.2015
BE04.11.2015
CY04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
MK04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
TR04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
IE24.03.2016
LU24.03.2016
CH31.03.2016
LI31.03.2016
MT31.03.2016
Former [2018/30]HU24.03.2010
AT04.11.2015
BE04.11.2015
CY04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
MK04.11.2015
MT04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
TR04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
IE24.03.2016
LU24.03.2016
CH31.03.2016
LI31.03.2016
Former [2018/28]HU24.03.2010
AT04.11.2015
BE04.11.2015
CY04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
MK04.11.2015
MT04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
IE24.03.2016
LU24.03.2016
CH31.03.2016
LI31.03.2016
Former [2017/47]AT04.11.2015
BE04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
MT04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
IE24.03.2016
LU24.03.2016
CH31.03.2016
LI31.03.2016
Former [2017/07]AT04.11.2015
BE04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
IE24.03.2016
LU24.03.2016
CH31.03.2016
LI31.03.2016
Former [2017/03]AT04.11.2015
BE04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
LU24.03.2016
Former [2016/49]AT04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
MC04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SI04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
LU24.03.2016
BE31.03.2016
Former [2016/47]AT04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
LU24.03.2016
BE31.03.2016
Former [2016/39]AT04.11.2015
CZ04.11.2015
DK04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
BE31.03.2016
Former [2016/38]AT04.11.2015
CZ04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SK04.11.2015
SM04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
BE31.03.2016
Former [2016/36]AT04.11.2015
CZ04.11.2015
EE04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
NL04.11.2015
PL04.11.2015
RO04.11.2015
SE04.11.2015
SK04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
BE31.03.2016
Former [2016/34]AT04.11.2015
CZ04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
NL04.11.2015
PL04.11.2015
SE04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
Former [2016/25]AT04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
LV04.11.2015
NL04.11.2015
PL04.11.2015
SE04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
Former [2016/24]AT04.11.2015
FI04.11.2015
HR04.11.2015
LT04.11.2015
NL04.11.2015
PL04.11.2015
SE04.11.2015
NO04.02.2016
GR05.02.2016
IS04.03.2016
PT04.03.2016
Former [2016/23]HR04.11.2015
LT04.11.2015
NL04.11.2015
SE04.11.2015
NO04.02.2016
IS04.03.2016
Former [2016/22]LT04.11.2015
NL04.11.2015
NO04.02.2016
IS04.03.2016
Former [2016/21]LT04.11.2015
NO04.02.2016
Former [2016/20]LT04.11.2015
Cited inInternational search[Y]WO2007056118  (WYETH CORP [US], et al);
by applicantWO9633978
 WO9633980
 US6002008
 US6288082
 US6297258
 US6387371
 US6399063
 US6821515
 US2005059678
 US2007104721
OppositionWO2007056118
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.