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Extract from the Register of European Patents

EP About this file: EP2396429

EP2396429 - COMBINATIONS OF POLYMORPHISMS FOR DETERMINING ALLELE-SPECIFIC EXPRESSION OF IGF2 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  01.04.2016
Database last updated on 16.09.2024
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting state
Updated state(s): MT		published on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Orion Genomics, LLC
4041 Forest Park Blvd.
St. Louis, MO 63108 / US
[2011/51]
Inventor(s)01 / ORDWAY, Jared
4266 Castleman Avenue
St. Louis Missouri 63110 / US
02 / MALONEY, Rebecca
13581 Lavender Mist Lane
Centreville Virginia 20120 / US
03 / LAKEY, Nathan
2040 Wilson Ridge Lane
Chesterfield Missouri 63005 / US
04 / BUDIMAN, Muhammad A.
144 Spruce Tree Lane
Manchester, Missouri 63021 / US
 [2011/51]
Representative(s)Campbell, Patrick John Henry, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2015/22]
Former [2011/51]Campbell, Patrick John Henry, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Application number, filing date10741738.811.02.2010
WO2010US23939
Priority number, dateUS20090207450P11.02.2009         Original published format: US 207450 P
[2011/51]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010093820
Date:19.08.2010
Language:EN
[2010/33]
Type: A2 Application without search report 
No.:EP2396429
Date:21.12.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 19.08.2010 takes the place of the publication of the European patent application.
[2011/51]
Type: B1 Patent specification 
No.:EP2396429
Date:27.05.2015
Language:EN
[2015/22]
Search report(s)International search report - published on:US14.10.2010
(Supplementary) European search report - dispatched on:EP27.09.2012
ClassificationIPC:C12Q1/68
[2011/51]
CPC:
C12Q1/6883 (EP,US); C12Q2600/156 (EP,US); C12Q2600/16 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/51]
Extension statesAL05.08.2011
BA05.08.2011
RS05.08.2011
TitleGerman:KOMBINATIONEN AUS POLYMORPHISMEN ZUR BESTIMMUNG VON ALLELSPEZIFISCHER IGF2-EXPRESSION[2011/51]
English:COMBINATIONS OF POLYMORPHISMS FOR DETERMINING ALLELE-SPECIFIC EXPRESSION OF IGF2[2011/51]
French:COMBINAISONS DE POLYMORPHISMES DESTINÉES À DÉTERMINER L'EXPRESSION SPÉCIFIQUE DES ALLÈLES D'IGF2[2011/51]
Entry into regional phase05.08.2011National basic fee paid 
05.08.2011Search fee paid 
05.08.2011Designation fee(s) paid 
05.08.2011Examination fee paid 
Examination procedure05.08.2011Examination requested  [2011/51]
23.04.2013Amendment by applicant (claims and/or description)
06.09.2013Despatch of a communication from the examining division (Time limit: M06)
16.01.2014Reply to a communication from the examining division
28.08.2014Communication of intention to grant the patent
13.02.2015Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
10.04.2015Fee for grant paid
10.04.2015Fee for publishing/printing paid
10.04.2015Receipt of the translation of the claim(s)
Divisional application(s)EP15163893.9  / EP2955234
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.09.2013
Opposition(s)01.03.2016No opposition filed within time limit [2016/18]
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
10.04.2015Request for further processing filed
10.04.2015Full payment received (date of receipt of payment)
Request granted
24.04.2015Decision despatched
Fees paidRenewal fee
15.02.2012Renewal fee patent year 03
12.02.2013Renewal fee patent year 04
12.02.2014Renewal fee patent year 05
11.02.2015Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU11.02.2010
AT27.05.2015
BE27.05.2015
CY27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
MK27.05.2015
NL27.05.2015
PL27.05.2015
RO27.05.2015
SE27.05.2015
SI27.05.2015
SK27.05.2015
SM27.05.2015
TR27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
IE11.02.2016
LU11.02.2016
MT29.02.2016
[2018/31]
Former [2018/29]HU11.02.2010
AT27.05.2015
BE27.05.2015
CY27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
MK27.05.2015
MT27.05.2015
NL27.05.2015
PL27.05.2015
RO27.05.2015
SE27.05.2015
SI27.05.2015
SK27.05.2015
SM27.05.2015
TR27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
IE11.02.2016
LU11.02.2016
Former [2018/28]HU11.02.2010
AT27.05.2015
BE27.05.2015
CY27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
MK27.05.2015
MT27.05.2015
NL27.05.2015
PL27.05.2015
RO27.05.2015
SE27.05.2015
SI27.05.2015
SK27.05.2015
SM27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
IE11.02.2016
LU11.02.2016
Former [2017/40]AT27.05.2015
BE27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
MT27.05.2015
NL27.05.2015
PL27.05.2015
RO27.05.2015
SE27.05.2015
SI27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
IE11.02.2016
LU11.02.2016
Former [2017/07]AT27.05.2015
BE27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
PL27.05.2015
RO27.05.2015
SI27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
IE11.02.2016
LU11.02.2016
Former [2016/43]AT27.05.2015
BE27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
PL27.05.2015
RO27.05.2015
SI27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
LU11.02.2016
Former [2016/42]AT27.05.2015
BE27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
MC27.05.2015
PL27.05.2015
RO27.05.2015
SI27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2016/36]AT27.05.2015
BE27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
PL27.05.2015
RO27.05.2015
SI27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2016/24]AT27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
PL27.05.2015
RO27.05.2015
SI27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
BE29.02.2016
Former [2016/10]AT27.05.2015
CZ27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
PL27.05.2015
RO27.05.2015
SK27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2016/09]AT27.05.2015
DK27.05.2015
EE27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2016/07]AT27.05.2015
DK27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2015/51]AT27.05.2015
FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2015/50]FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
BG27.08.2015
NO27.08.2015
GR28.08.2015
IS27.09.2015
PT28.09.2015
Former [2015/49]FI27.05.2015
HR27.05.2015
LT27.05.2015
LV27.05.2015
NO27.08.2015
GR28.08.2015
PT28.09.2015
Documents cited:Search[Y]WO0004187  (UNIV JOHNS HOPKINS [US]) [Y] 1-15 * page 31; example 1 * * the whole document *;
 [XPY]WO2009021054  (ORION GENOMICS LLC [US], et al) [XP] 1-12,14,15 * page 45, paragraph 0147; tables 6-8 * [Y] 13;
 [Y]  - WOODSON KAREN ET AL, "Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women", NATIONAL CANCER INSTITUTE. JOURNAL (ONLINE), OXFORD UNIVERSITY PRESS, GB, (20040303), vol. 96, no. 5, doi:10.1093/JNCI/DJH042, ISSN 1460-2105, pages 407 - 410, XP002504114 [Y] 1-15 * page 408, column 1, paragraph 2 * * the whole document *

DOI:   http://dx.doi.org/10.1093/JNCI/DJH042
 [Y]  - CUI H ET AL, "Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability", NATURE MEDICINE, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (19981101), vol. 4, no. 11, doi:10.1038/3260, ISSN 1078-8956, pages 1276 - 1280, XP002233806 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/3260
 [A]  - H. T. BJORNSSON ET AL, "Epigenetic Specificity of Loss of Imprinting of the IGF2 Gene in Wilms Tumors", JNCI JOURNAL OF THE NATIONAL CANCER INSTITUTE, (20070815), vol. 99, no. 16, doi:10.1093/jnci/djm069, ISSN 0027-8874, pages 1270 - 1273, XP055038442 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1093/jnci/djm069
 [A]  - YUN K ET AL, "Analysis of IGF2 gene imprinting in breast and colorectal cancer by allele specific-PCR", JOURNAL OF PATHOLOGY, JOHN WILEY & SONS LTD, GB, (19990101), vol. 187, doi:10.1002/(SICI)1096-9896(199904)187:5<518::AID-PATH276>3.0.CO;2-3, ISSN 0022-3417, pages 518 - 522, XP002953234 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/(SICI)1096-9896(199904)187:5<518::AID-PATH276>3.0.CO;2-3
 [A]  - BARRATT ET AL, "Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design.", ANNALS OF HUMAN GENETICS, (20021101), vol. 66, no. 5-6, doi:10.1017/S0003480002001252, ISSN 0003-4800, pages 393 - 405, XP055038536 [A] 1-15 * table 2 *

DOI:   http://dx.doi.org/10.1046/j.1469-1809.2002.00125.x
International search[A]US2001007749  (FEINBERG ANDREW P [US]);
 [A]US2006292626  (KENNEDY GIULIA [US]);
 [A]US2008220983  (TRINKLEIN NATHAN [US], et al)
by applicantUS3817837
 US3850752
 US3939350
 US3996345
 US4275149
 US4277437
 US4366241
 US5210015
 US5310893
 WO9511995
 US5451512
 US5468613
 US5487972
 US5491063
 US5571673
 US5604099
 US5804375
 US6117635
 US6326145
 WO2004003003
    - DECHIARA TM ET AL., CELL, (1991), vol. 64, pages 849 - 859
    - RAINIER S ET AL., NATURE, (1993), vol. 362, pages 747 - 749
    - OGAWA ET AL., NATURE, (1993), vol. 362, pages 749 - 751
    - FALLS ET AL., AJP, (1999), vol. 154, pages 635 - 647
    - KINOCHI ET AL., CANCER LETTERS, (1996), vol. 107, pages 105 - 108
    - NISHIHARA S., INT. JOUR. ONCOL., (2000), vol. 17, pages 317 - 322
    - CUI H, NATURE MEDICINE, (1998), vol. 4-11, pages 1276 - 1280
    - NAKAGAWA H, PNAS, (2001), vol. 98-2, pages 591 - 596
    - OGAWA ET AL., NATURE GENETICS, (1993), vol. 5, pages 408 - 412
    - CUI H, SCIENCE, (2003), vol. 299, page 1753
    - CUI H ET AL., NATURE MEDICINE, (1998), vol. 4-11, pages 1276 - 1280
    - WOODSON K ET AL., JNCI, (2004), vol. 96, pages 407 - 410
    - CRUZ-CORREA M ET AL., GASTROENTEROLOGY, (2004), vol. 126, pages 964 - 970
    - CONNER ET AL., PROC. NATL. ACAD. SCI. USA, (1983), vol. 80, pages 278 - 282
    - HOLLAND ET AL., PROC. NATL ACAD. SCI. USA, (1988), vol. 88, pages 7276 - 7280
    - WHITCOMBE ET AL., NATURE BIOTECHNOLOGY, (1999), vol. 17, pages 804 - 807
    - NAZARENKO ET AL., NUC. ACIDS RES., (1997), vol. 25, pages 2516 - 2521
    - KANEDA ET AL., PROC. NATL. ACAD. SCI. USA, (2007), vol. 104, no. 52, pages 20926 - 20931
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.