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Extract from the Register of European Patents

EP About this file: EP2486411

EP2486411 - MULTIPLEX QUANTITATION OF INDIVIDUAL RECOMBINANT PROTEINS IN A MIXTURE BY SIGNATURE PEPTIDES AND MASS SPECTROMETRY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  04.11.2015
Database last updated on 03.09.2024
Most recent event   Tooltip04.11.2015Change or deletion - application deemed withdrawnpublished on 02.12.2015  [2015/49]
Applicant(s)For all designated states
Symphogen A/S
Elektrovej Building 375
2800 Kgs. Lyngby / DK
[2012/33]
Inventor(s)01 / FRANDSEN, Torben
Dalgas Boulevard 163 st
DK-2000 Frederiksberg C / DK
02 / NAESTED, Henrik
Kikhanebakken 54
DK-2840 Holte / DK
03 / SEN, Jette, Wagtberg
Pilevangsdal 1
DK-2630 Taastrup / DK
04 / JENSEN, Pernille, Foged
Sognevangen 1
DK-2630 Taastrup / DK
 [2012/33]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2013/35]Vossius & Partner
P.O. Box 86 07 67
81634 München / DE
Former [2012/33]Bendiksen, Henrik, et al
Symphogen A/S Elektrovej Build. 375
2800 Kgs. Lyngby / DK
Application number, filing date10774121.707.10.2010
WO2010DK50258
Priority number, dateDK2009000111209.10.2009         Original published format: DK 200901112
US20090256232P29.10.2009         Original published format: US 256232 P
[2012/33]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2011042027
Date:14.04.2011
Language:EN
[2011/15]
Type: A2 Application without search report 
No.:EP2486411
Date:15.08.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 14.04.2011 takes the place of the publication of the European patent application.
[2012/33]
Search report(s)International search report - published on:EP22.09.2011
ClassificationIPC:G01N33/68
[2012/33]
CPC:
G01N33/6851 (EP,KR,US); G01N33/68 (KR); C07K1/14 (KR);
G01N27/62 (KR); G01N33/53 (KR); G01N33/6842 (EP,KR,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/33]
TitleGerman:MULTIPLEXE QUANTIFIZIERUNG VON EINZELNEN REKOMBINANTEN PROTEINEN IN EINER MISCHUNG DURCH SIGNATURPEPTIDE UND MASSENSPEKTROMETRIE[2012/33]
English:MULTIPLEX QUANTITATION OF INDIVIDUAL RECOMBINANT PROTEINS IN A MIXTURE BY SIGNATURE PEPTIDES AND MASS SPECTROMETRY[2012/33]
French:QUANTIFICATION MULTIPLEXE DE PROTÉINES RECOMBINANTES INDIVIDUELLES DANS UN MÉLANGE PAR DES PEPTIDES DE SIGNATURE ET SPECTROMÉTRIE DE MASSE[2012/33]
Entry into regional phase09.05.2012National basic fee paid 
09.05.2012Designation fee(s) paid 
09.05.2012Examination fee paid 
Examination procedure09.05.2012Examination requested  [2012/33]
30.11.2012Amendment by applicant (claims and/or description)
21.11.2014Despatch of a communication from the examining division (Time limit: M04)
02.12.2014Application deemed to be withdrawn, date of legal effect  [2015/36]
02.04.2015Application deemed to be withdrawn, date of legal effect  [2015/49]
29.04.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/49]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.11.2014
Fees paidRenewal fee
31.10.2012Renewal fee patent year 03
24.10.2013Renewal fee patent year 04
23.10.2014Renewal fee patent year 05
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Cited inInternational search[I]WO2005124341  (ANDERSON NORMAN LEIGH [US]) [I] 1-137 * abstract *;
 [I]  - KESHISHIAN HASMIK ET AL, "Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution.", MOLECULAR & CELLULAR PROTEOMICS : MCP DEC 2007 LNKD- PUBMED:17939991, (200712), vol. 6, no. 12, ISSN 1535-9476, pages 2212 - 2229, XP002586395 [I] 1-137 * abstract * * introductory section * * section ' Experimental procedures' * * section 'Alternative Enrichment Strategies' on page 2227 * * page 2228, last phrase *

DOI:   http://dx.doi.org/10.1074/MCP.M700354-MCP200
 [I]  - ANDERSON L ET AL, "Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins", MOLECULAR & CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US LNKD- DOI:10.1074/MCP.M500331-MCP200, vol. 5, ISSN 1535-9476, (20051206), pages 573 - 588, (20051206), XP002484129 [I] 1-137 * abstract * * section 'experimental procedures' *

DOI:   http://dx.doi.org/10.1074/mcp.M500331-MCP200
 [A]  - ANDERSON N L ET AL, "Mass Spectrometric Quantitation of Peptides and Proteins Using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA)", JOURNAL OF PROTEOME RESEARCH, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/PR034086H, (20040206), vol. 3, ISSN 1535-3893, pages 235 - 244, XP002484128 [A] 1-137 * abstract * * section 'materials and methods' *

DOI:   http://dx.doi.org/10.1021/pr034086h
 [A]  - CROWTHER J ET AL, "Determination of nanogram levels of peptide drug in rabbit and human plasma using high-performance liquid chromatography coupled with electrospray ionization mass spectrometry", ANALYTICAL CHEMISTRY, (1994), vol. 66, no. 14, ISSN 0003-2700, pages 2356 - 2361, XP002586396 [A] 1-137 * abstract *
 [A]  - STREIT F ET AL, "Rapid Liquid Chromatography-Tandem Mass Spectrometry Routine Method for Simultaneous Determination of Sirolimus, Everolimus, Tacrolimus and Cyclosporin A in Whole Blood", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 48, no. 6, ISSN 0009-9147, (20020101), pages 955 - 958, (20090821), XP002542503 [A] 1-137 * page 955 *
 [A]  - JACKSON A ET AL, "Enrichment of lower abundance peptides from human plasma using SISCAPA", MOLECULAR & CELLULAR PROTEOMICS, & HUPO 5TH ANNUAL WORLD CONGRESS; LONG BEACH, CA, USA; OCTOBER 28 NOVEMBER 01, 2006, (200610), vol. 5, no. 10, Suppl. S, ISSN 1535-9476, page S333, XP002646499 [A] 1-137 * abstract *
by applicantWO2004031730
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    - DUBOIS ET AL., ANAL CHEM., (20080301), vol. 80, no. 5, pages 1737 - 45
    - NICOL ET AL., MOL CELL PROTEOMICS., (200810), vol. 7, no. 10, pages 1974 - 82
    - ACKERMANN; BERNA, EXPERT REV PROTEOMICS., (200704), vol. 4, no. 2, pages 175 - 86
    - ONG; MANN, NATURE CHEMICAL BIOLOGY, (2005), vol. 1, pages 252 - 262
    - YAN; CHEN HENRY STEWART, "PUBLICATIONS", BRIEFINGS IN FUNCTIONAL GENOMICS AND PROTEOMICS., (20051201), vol. 4, no. 1, pages 1473 - 9550
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.