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Extract from the Register of European Patents

EP About this file: EP2494351

EP2494351 - COLON AND RECTAL TUMOR MARKERS AND METHODS OF USE THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.04.2017
Database last updated on 03.09.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Externautics S.p.A.
Via Fiorentina, 1
53100 Siena / IT
[2012/36]
Inventor(s)01 / GRIFANTINI, Renata
c/o Externautics S.P.A
Via Fiorentina 1
53100 Siena / IT
02 / PILERI, Piero
c/o Externautics S.P.A.
Via Fiorentina 1
53100 Siena / IT
03 / CAMPAGNOLI, Susanna
c/o Externautics S.P.A.
Via Fiorentina 1
53100 Siena / IT
04 / GRANDI, Alberto
c/o Externautics S.P.A.
Via Fiorentina 1
53100 Siena / IT
05 / PARRI, Matteo
c/o Externautics S.P.A.
Via Fiorentina 1
53100 Siena / IT
06 / PIERLEONI, Andrea
c/o Externautics S.P.A.
Via Fiorentina 1
53100 Siena / IT
07 / NOGAROTTO, Renzo
c/o Externautics S.P.A.
Via Fiorentina 1
53100 Siena / IT
 [2012/36]
Representative(s)Banfi, Paolo
Bianchetti & Minoja with
Trevisan & Cuonzo IPS Srl
Via Plinio, 63
20129 Milano / IT
[N/P]
Former [2016/23]Banfi, Paolo
Bianchetti Bracco Minoja S.r.l.
Via Plinio, 63
20129 Milano / IT
Former [2012/36]Banfi, Paolo
Bianchetti Bracco Minoja S.r.l. Via Plinio, 63
20129 Milano / IT
Application number, filing date10778592.526.10.2010
[2016/23]
WO2010EP66144
Priority number, dateEP2009017405926.10.2009         Original published format: EP 09174059
[2012/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011051276
Date:05.05.2011
Language:EN
[2011/18]
Type: A1 Application with search report 
No.:EP2494351
Date:05.09.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 05.05.2011 takes the place of the publication of the European patent application.
[2012/36]
Type: B1 Patent specification 
No.:EP2494351
Date:08.06.2016
Language:EN
[2016/23]
Search report(s)International search report - published on:EP05.05.2011
ClassificationIPC:G01N33/50, G01N33/574
[2012/36]
CPC:
G01N33/57419 (EP,US); G01N2500/10 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/36]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:KOLON- UND REKTALTUMORMARKER SOWIE VERFAHREN ZU IHRER VERWENDUNG[2012/36]
English:COLON AND RECTAL TUMOR MARKERS AND METHODS OF USE THEREOF[2012/36]
French:MARQUEURS DE TUMEURS DU RECTUM ET DU CÔLON, ET LEURS MÉTHODES D'UTILISATION[2012/36]
Entry into regional phase22.05.2012National basic fee paid 
22.05.2012Designation fee(s) paid 
22.05.2012Examination fee paid 
Examination procedure22.05.2012Examination requested  [2012/36]
20.12.2012Amendment by applicant (claims and/or description)
25.07.2013Despatch of a communication from the examining division (Time limit: M04)
27.11.2013Reply to a communication from the examining division
10.04.2014Despatch of a communication from the examining division (Time limit: M06)
10.10.2014Reply to a communication from the examining division
15.05.2015Communication of intention to grant the patent
08.09.2015Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
22.09.2015Communication of intention to grant the patent
14.01.2016Fee for grant paid
14.01.2016Fee for publishing/printing paid
14.01.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.07.2013
Opposition(s)09.03.2017No opposition filed within time limit [2017/20]
Fees paidRenewal fee
29.10.2012Renewal fee patent year 03
28.10.2013Renewal fee patent year 04
27.10.2014Renewal fee patent year 05
28.04.2016Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.10.201506   M06   Fee paid on   28.04.2016
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.10.2010
AL08.06.2016
AT08.06.2016
BE08.06.2016
BG08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
HR08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
MK08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
TR08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE26.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
MT31.10.2016
[2018/46]
Former [2018/38]HU26.10.2010
AT08.06.2016
BE08.06.2016
BG08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
HR08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
MK08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
TR08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE26.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
MT31.10.2016
Former [2018/32]HU26.10.2010
AT08.06.2016
BE08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
HR08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
MK08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
TR08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE26.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
MT31.10.2016
Former [2018/29]HU26.10.2010
AT08.06.2016
BE08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
HR08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
MK08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
TR08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE26.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
Former [2018/28]HU26.10.2010
AT08.06.2016
BE08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
HR08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
MK08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE26.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
Former [2017/51]AT08.06.2016
BE08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE26.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
Former [2017/43]AT08.06.2016
BE08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
LU26.10.2016
CH31.10.2016
LI31.10.2016
Former [2017/37]AT08.06.2016
BE08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
SM08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
CH31.10.2016
LI31.10.2016
Former [2017/11]AT08.06.2016
BE08.06.2016
CZ08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SK08.06.2016
SM08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
Former [2017/10]BE08.06.2016
CZ08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
SK08.06.2016
NO08.09.2016
GR09.09.2016
IS08.10.2016
Former [2017/09]CZ08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
RO08.06.2016
RS08.06.2016
SE08.06.2016
NO08.09.2016
GR09.09.2016
Former [2016/52]ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
RS08.06.2016
SE08.06.2016
NO08.09.2016
GR09.09.2016
Former [2016/51]ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
RS08.06.2016
NO08.09.2016
GR09.09.2016
Former [2016/50]ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
RS08.06.2016
NO08.09.2016
Former [2016/49]FI08.06.2016
LT08.06.2016
NL08.06.2016
NO08.09.2016
Former [2016/46]LT08.06.2016
NO08.09.2016
Cited inInternational search[X]WO9932639  (REGENERON PHARMA [US]) [X] 1 * AR-1 = ANGPTL7;;; figure 4; claim - *;
 [X]EP1696029  (GENENTECH INC [US]) [X] 1-6* SEQ ID NO: 19= NL4 = ANGPTL7;; paragraphs [0189] , [0192] , [0194] , [0243] , [0250]; claim - *;
 [X]US2007237770  (LAI ALBERT [US], et al) [X] 1-6 * SLC39A10; page 76, paragraph 26; claim - *;
 [A]WO2008004719  (ORIENTBIO CO LTD [KR], et al) [A] 1-6 * page 6, line 15; claim - * * page 11, line 2 - page 12, line 3 *;
 [A]  - AUSCH C ET AL, "Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients", EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, LONDON, GB, vol. 35, no. 11, doi:DOI:10.1016/J.EJSO.2009.02.007, ISSN 0748-7983, (20090228), pages 1164 - 1168, (20090228), XP026681636 [A] 1-11 * abstract *

DOI:   http://dx.doi.org/10.1016/j.ejso.2009.02.007
by applicantJP2002360254
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 US20060432604
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