blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2501384

EP2501384 - METHOD OF TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R KINASE ACTIVITY [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  29.09.2023
Database last updated on 03.04.2025
FormerThe patent has been granted
Status updated on  16.05.2018
Most recent event   Tooltip29.09.2023Patent maintained (B2 publication)published on 01.11.2023  [2023/44]
Applicant(s)For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
[2023/44]
Former [2012/39]For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
Inventor(s)01 / GALLAGHER, Neil
Novartis Pharma AG
Postfach
CH-4002 Basel / CH
02 / YIN, Ophelia
66 Henning Terrace
Denville New Jersey 07834 / US
 [2012/39]
Representative(s)Aera A/S
Niels Hemmingsens Gade 10, 5th Floor
1153 Copenhagen K / DK
[2023/44]
Former [2016/07]Roth, Peter Richard
Novartis Pharma AG
Patent Department
4002 Basel / CH
Former [2012/39]Roth, Peter Richard
Novartis Pharma AG Patent Department
4002 Basel / CH
Application number, filing date10781781.917.11.2010
[2016/07]
WO2010US56926
Priority number, dateUS20090261812P17.11.2009         Original published format: US 261812 P
[2012/39]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011062927
Date:26.05.2011
Language:EN
[2011/21]
Type: A1 Application with search report 
No.:EP2501384
Date:26.09.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 26.05.2011 takes the place of the publication of the European patent application.
[2012/39]
Type: B1 Patent specification 
No.:EP2501384
Date:17.02.2016
Language:EN
[2016/07]
Type: B2 New European patent specification 
No.:EP2501384
Date:01.11.2023
Language:EN
[2023/44]
Search report(s)International search report - published on:EP26.05.2011
ClassificationIPC:A61K31/506, A61P35/00, A61K9/00, C07D239/69
[2015/27]
CPC:
A61K31/506 (EP,KR,RU,US); A61K9/0095 (EP,KR,US); A61P11/00 (EP);
A61P11/06 (EP); A61P17/00 (EP); A61P17/06 (EP);
A61P19/02 (EP); A61P19/04 (EP); A61P25/00 (EP);
A61P25/28 (EP); A61P29/00 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/06 (EP); A61P43/00 (EP);
A61P9/12 (EP); C07D239/69 (EP,KR,US); A61K31/505 (RU) (-)
Former IPC [2012/39]A61K31/506, A61P35/00, A61K9/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/39]
Extension statesBA18.06.2012
ME18.06.2012
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON DURCH BCR-ABL, C-KIT, DDR1, DDR2 ODER PDGF-R-KINASEAKTIVITÄT VERMITTELTEN PROLIFERATIVEN ERKRANKUNGEN UND ANDEREN KRANKHEITSZUSTÄNDEN[2012/39]
English:METHOD OF TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R KINASE ACTIVITY[2012/39]
French:MÉTHODE DE TRAITEMENT DE TROUBLES PROLIFÉRATIFS ET D'AUTRES AFFECTIONS PATHOLOGIQUES MÉDIÉS PAR BCR-ABL, C-KIT, DDR1, DDR2 OU L'ACTIVITÉ KINASE DU PDGF-R[2012/39]
Entry into regional phase18.06.2012National basic fee paid 
18.06.2012Designation fee(s) paid 
18.06.2012Examination fee paid 
Examination procedure18.06.2012Examination requested  [2012/39]
17.01.2013Amendment by applicant (claims and/or description)
10.07.2013Despatch of a communication from the examining division (Time limit: M06)
20.01.2014Reply to a communication from the examining division
02.04.2014Observations by third parties
08.04.2014Observations by third parties
19.09.2014Despatch of a communication from the examining division (Time limit: M04)
05.12.2014Reply to a communication from the examining division
13.08.2015Communication of intention to grant the patent
10.12.2015Fee for grant paid
10.12.2015Fee for publishing/printing paid
10.12.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  10.07.2013
Opposition(s)Opponent(s)01  14.11.2016  17.11.2016  ADMISSIBLE
Fresenius Kabi Deutschland GmbH
Else-Kröner-Str. 1
61352 Bad Homburg / DE
Opponent's representative
Fresenius Kabi Deutschland GmbH, et al, et al
Patent Department
Pharmaceuticals Division
Borkenberg 14
61440 Oberursel / DE
 02  17.11.2016  23.11.2016  ADMISSIBLE
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 03  17.11.2016  23.11.2016  ADMISSIBLE
TEVA PHARMACEUTICAL INDUSTRIES, LTD.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
D Young & Co LLP, et al, et al
3 Noble Street
London EC2V 7BQ / GB
 04  17.11.2016  23.11.2016  ADMISSIBLE
Intas Pharmaceuticals Ltd.
2nd Floor Chinubhai Centre
Ashram Road
Ahmedabad 380009
GUJ / IN
Opponent's representative
Isarpatent, et al, et al
Patent- und Rechtsanwälte Barth
Charles Hassa Peckmann & Partner mbB
Friedrichstrasse 31
80801 München / DE
 05  17.11.2016  23.11.2016  ADMISSIBLE
Generics (U.K.) Limited
Station Close
Potters Bar
Hertfordshire EN6 1TL / GB
Opponent's representative
Elkington and Fife LLP, et al, et al
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 [N/P]
Former [2021/47]
Opponent(s)01  14.11.2016  17.11.2016  ADMISSIBLE
Fresenius Kabi Deutschland GmbH
Else-Kröner-Str. 1
61352 Bad Homburg / DE
Opponent's representative
Fresenius Kabi Deutschland GmbH, et al, et al
Patent Department
Pharmaceuticals Division
Borkenberg 14
61440 Oberursel / DE
 02  17.11.2016  23.11.2016  ADMISSIBLE
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 03  17.11.2016  23.11.2016  ADMISSIBLE
TEVA PHARMACEUTICAL INDUSTRIES, LTD.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
D Young & Co LLP, et al, et al
120 Holborn
London EC1N 2DY / GB
 04  17.11.2016  23.11.2016  ADMISSIBLE
Intas Pharmaceuticals Ltd.
2nd Floor Chinubhai Centre
Ashram Road
Ahmedabad 380009
GUJ / IN
Opponent's representative
Isarpatent, et al, et al
Patent- und Rechtsanwälte Barth
Charles Hassa Peckmann & Partner mbB
Friedrichstrasse 31
80801 München / DE
 05  17.11.2016  23.11.2016  ADMISSIBLE
Generics (U.K.) Limited
Station Close
Potters Bar
Hertfordshire EN6 1TL / GB
Opponent's representative
Elkington and Fife LLP, et al, et al
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
Former [2020/49]
Opponent(s)01  14.11.2016  17.11.2016  ADMISSIBLE
Fresenius Kabi Deutschland GmbH
Else-Kröner-Str. 1
61352 Bad Homburg / DE
Opponent's representative
Fresenius Kabi Deutschland GmbH, et al, et al
Patent Department
Pharmaceuticals Division
Borkenberg 14
61440 Oberursel / DE
 02  17.11.2016  23.11.2016  ADMISSIBLE
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 03  17.11.2016  23.11.2016  ADMISSIBLE
Teva Pharmaceutical Industries Ltd
5 Basel Street
P.O. Box 3190
49131 Petah Tiqva / IL
Opponent's representative
D Young & Co LLP, et al, et al
120 Holborn
London EC1N 2DY / GB
 04  17.11.2016  23.11.2016  ADMISSIBLE
Intas Pharmaceuticals Ltd.
2nd Floor Chinubhai Centre
Ashram Road
Ahmedabad 380009
GUJ / IN
Opponent's representative
Isarpatent, et al, et al
Patent- und Rechtsanwälte Behnisch Barth Charles
Hassa Peckmann & Partner mbB
Friedrichstrasse 31
80801 München / DE
 05  17.11.2016  23.11.2016  ADMISSIBLE
Generics (U.K.) Limited
Station Close
Potters Bar
Hertfordshire EN6 1TL / GB
Opponent's representative
Elkington and Fife LLP, et al, et al
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
Former [2018/52]
Opponent(s)01  14.11.2016  17.11.2016  ADMISSIBLE
Fresenius Kabi Deutschland GmbH
Else-Kröner-Str. 1
61352 Bad Homburg / DE
Opponent's representative
Fresenius Kabi Deutschland GmbH, et al, et al
Patent Department
Pharmaceuticals Division
Borkenberg 14
61440 Oberursel / DE
 02  17.11.2016  23.11.2016  ADMISSIBLE
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 03  17.11.2016  23.11.2016  ADMISSIBLE
Teva Pharmaceutical Industries Ltd
5 Basel Street
P.O. Box 3190
49131 Petah Tiqva / IL
Opponent's representative
D Young & Co LLP, et al, et al
120 Holborn
London EC1N 2DY / GB
 04  17.11.2016  23.11.2016  ADMISSIBLE
Intas Pharmaceuticals Ltd.
2nd Floor Chinubhai Centre
Ashram Road
Ahmedabad 380009
GUJ / IN
Opponent's representative
Accord Healthcare, S.L.U., et al, et al
World Trade Center
Moll de Barcelona s/n
Edifici Est, 6ª planta
08039 Barcelona / ES
 05  17.11.2016  23.11.2016  ADMISSIBLE
Generics (U.K.) Limited
Station Close
Potters Bar
Hertfordshire EN6 1TL / GB
Opponent's representative
Elkington & Fife LLP, et al, et al
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
Former [2016/52]
Opponent(s)01  14.11.2016  17.11.2016  ADMISSIBLE
Fresenius Kabi Deutschland GmbH
Else-Kröner-Str. 1
61352 Bad Homburg / DE
Opponent's representative
Fresenius Kabi Deutschland GmbH, et al, et al
Patent Department
Pharmaceuticals Division
Borkenberg 14
61440 Oberursel / DE
 02  17.11.2016  23.11.2016  ADMISSIBLE
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm & Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 03  17.11.2016  23.11.2016  ADMISSIBLE
Teva Pharmaceutical Industries Ltd
5 Basel Street
P.O. Box 3190
49131 Petah Tiqva / IL
Opponent's representative
D Young & Co LLP, et al, et al
120 Holborn
London EC1N 2DY / GB
 04  17.11.2016  23.11.2016  ADMISSIBLE
Intas Pharmaceuticals Ltd.
2nd Floor Chinubhai Centre
Ashram Road
Ahmedabad 380009
GUJ / IN
Opponent's representative
Accord Healthcare, S.L.U., et al, et al
Department: Intellectual Property Europe
World Trade Center
Moll de Barcelona s/n
Edifici Est, 6ª planta
08039 Barcelona / ES
 05  17.11.2016  23.11.2016  ADMISSIBLE
Generics (U.K.) Limited
Station Close
Potters Bar
Hertfordshire EN6 1TL / GB
Opponent's representative
Cooke, Richard Spencer, et al, et al
Elkington and Fife LLP
Patents Department
3-4 Holborn Circus
London EC1N 2HA / GB
Former [2016/51]
Opponent(s)01  14.11.2016  17.11.2016  ADMISSIBLE
Fresenius Kabi Deutschland GmbH
Else-Kröner-Str. 1
61352 Bad Homburg / DE
Opponent's representative
Fresenius Kabi Deutschland GmbH, et al, et al
Patent Department
Pharmaceuticals Division
Borkenberg 14
61440 Oberursel / DE
09.01.2017Invitation to proprietor to file observations on the notice of opposition
18.05.2017Reply of patent proprietor to notice(s) of opposition
24.04.2018Date of oral proceedings
17.05.2018Despatch of minutes of oral proceedings
17.05.2018Despatch of communication that the patent will be revoked
23.01.2023Despatch of a communication from the opposition division (Time limit: M02)
19.05.2023Despatch of interlocutory decision in opposition
29.05.2023Legal effect of interlocutory decision in opposition
18.09.2023Despatch of communication that the patent will be maintained as amended
Appeal following opposition09.07.2018Appeal received No.  T1806/18
27.09.2018Statement of grounds filed
21.10.2021Result of appeal procedure: maintenance in amended form
25.11.2022Despatch of the decision of the Board of Appeal
21.10.2021Date of oral proceedings
Fees paidRenewal fee
13.11.2012Renewal fee patent year 03
18.11.2013Renewal fee patent year 04
10.11.2014Renewal fee patent year 05
10.11.2015Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipSM08.06.2018
MC30.11.2018
[2019/33]
Former [2018/40]SM08.06.2018
Cited inInternational search[XI]WO2004005281  (NOVARTIS AG [CH], et al);
 [XI]WO2006119154  (NOVARTIS AG [CH], et al);
by applicantWO2004005281
 EP1533304
 WO2007015871
 WO2007015870
 WO2008037716
OppositionWO2008037716
 WO2004005281
 WO2006119154
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.