| EP2504323 - NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 19.01.2018 Database last updated on 28.03.2026 | |
| Former | The patent has been granted Status updated on 10.02.2017 | ||
| Former | Grant of patent is intended Status updated on 03.02.2017 | ||
| Former | Examination is in progress Status updated on 20.01.2017 | Most recent event Tooltip | 10.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 12.08.2020 [2020/33] | Applicant(s) | For all designated states ALLERGAN, INC. 2525 Dupont Drive Irvine, CA 92612 / US | [2017/11] |
| Former [2012/40] | For all designated states Allergan, Inc. 2525 Dupont Drive Irvine, CA 92612 / US | Inventor(s) | 01 /
HEIDELBAUGH, Todd M. 18886 Mount Castile Circle Fountain Valley, California 92708 / US | 02 /
NGUYEN, Phong X. 1048 Wingfoot Street Placentia, California 92870 / US | [2012/40] | Representative(s) | Hoffmann Eitle Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München / DE | [2017/11] |
| Former [2012/40] | HOFFMANN EITLE Patent- und Rechtsanwälte Arabellastrasse 4 81925 München / DE | Application number, filing date | 10782507.7 | 19.11.2010 | [2017/11] | WO2010US57361 | Priority number, date | US20090264038P | 24.11.2009 Original published format: US 264038 P | [2012/40] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2011066184 | Date: | 03.06.2011 | Language: | EN | [2011/22] | Type: | A1 Application with search report | No.: | EP2504323 | Date: | 03.10.2012 | Language: | EN | The application published by WIPO in one of the EPO official languages on 03.06.2011 takes the place of the publication of the European patent application. | [2012/40] | Type: | B1 Patent specification | No.: | EP2504323 | Date: | 15.03.2017 | Language: | EN | [2017/11] | Search report(s) | International search report - published on: | EP | 03.06.2011 | Classification | IPC: | C07D263/32, C07D277/24, C07D307/42, C07D333/16, C07D409/04, A61K31/435, A61P37/00 | [2012/40] | CPC: |
A61P1/00 (EP);
C07D307/42 (KR);
C07F9/65586 (US);
A61K31/34 (KR);
A61P1/02 (EP);
A61P1/04 (EP);
A61P11/00 (EP);
A61P11/06 (EP);
A61P11/16 (EP);
A61P13/12 (EP);
A61P17/00 (EP);
A61P17/02 (EP);
A61P17/04 (EP);
A61P17/06 (EP);
A61P19/00 (EP);
A61P19/02 (EP);
A61P19/04 (EP);
A61P19/08 (EP);
A61P19/10 (EP);
A61P21/04 (EP);
A61P25/00 (EP);
A61P25/04 (EP);
A61P25/28 (EP);
A61P27/00 (EP);
A61P27/02 (EP);
A61P27/06 (EP);
A61P29/00 (EP);
A61P3/10 (EP);
A61P31/04 (EP);
A61P35/04 (EP);
A61P37/00 (EP);
A61P37/06 (EP);
A61P37/08 (EP);
A61P39/02 (EP);
A61P5/14 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
C07D205/04 (EP,US);
C07D333/16 (EP,US);
C07D401/10 (EP,US);
C07D403/10 (EP,US);
C07D405/10 (EP,US);
C07D409/04 (EP,US);
C07D409/10 (EP,US);
C07D413/10 (EP,US);
C07D417/10 (EP,US);
C07F9/38 (KR);
C07F9/58 (US);
C07F9/653 (US);
C07F9/6539 (US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2012/40] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | NEUE VERBINDUNGEN ALS REZEPTORMODULATOREN MIT THERAPEUTISCHEM NUTZEN | [2012/40] | English: | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | [2012/40] | French: | NOUVEAUX COMPOSÉS SERVANT DE MODULATEURS DE RÉCEPTEURS PRÉSENTANT UNE UTILITÉ THÉRAPEUTIQUE | [2012/40] | Entry into regional phase | 21.06.2012 | National basic fee paid | 21.06.2012 | Designation fee(s) paid | 21.06.2012 | Examination fee paid | Examination procedure | 21.06.2012 | Amendment by applicant (claims and/or description) | 21.06.2012 | Examination requested [2012/40] | 22.09.2014 | Despatch of a communication from the examining division (Time limit: M04) | 22.01.2015 | Reply to a communication from the examining division | 11.04.2016 | Despatch of a communication from the examining division (Time limit: M04) | 13.05.2016 | Reply to a communication from the examining division | 06.10.2016 | Communication of intention to grant the patent | 11.01.2017 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 11.01.2017 | Fee for grant paid | 11.01.2017 | Fee for publishing/printing paid | 03.02.2017 | Information about intention to grant a patent | 03.02.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 22.09.2014 | Opposition(s) | 18.12.2017 | No opposition filed within time limit [2018/08] | Fees paid | Renewal fee | 26.11.2012 | Renewal fee patent year 03 | 27.11.2013 | Renewal fee patent year 04 | 26.11.2014 | Renewal fee patent year 05 | 30.11.2015 | Renewal fee patent year 06 | 28.11.2016 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 19.11.2010 | AL | 15.03.2017 | AT | 15.03.2017 | CY | 15.03.2017 | CZ | 15.03.2017 | DK | 15.03.2017 | EE | 15.03.2017 | ES | 15.03.2017 | FI | 15.03.2017 | HR | 15.03.2017 | IT | 15.03.2017 | LT | 15.03.2017 | LV | 15.03.2017 | MC | 15.03.2017 | MK | 15.03.2017 | NL | 15.03.2017 | PL | 15.03.2017 | RO | 15.03.2017 | RS | 15.03.2017 | SE | 15.03.2017 | SI | 15.03.2017 | SK | 15.03.2017 | SM | 15.03.2017 | TR | 15.03.2017 | BG | 15.06.2017 | NO | 15.06.2017 | GR | 16.06.2017 | IS | 15.07.2017 | PT | 17.07.2017 | IE | 19.11.2017 | LU | 19.11.2017 | MT | 19.11.2017 | BE | 30.11.2017 | CH | 30.11.2017 | LI | 30.11.2017 | [2020/33] |
| Former [2020/15] | HU | 19.11.2010 | |
| AT | 15.03.2017 | ||
| CY | 15.03.2017 | ||
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
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| MK | 15.03.2017 | ||
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| SI | 15.03.2017 | ||
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| SM | 15.03.2017 | ||
| TR | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
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| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| IE | 19.11.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| BE | 30.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2019/51] | HU | 19.11.2010 | |
| AT | 15.03.2017 | ||
| CY | 15.03.2017 | ||
| CZ | 15.03.2017 | ||
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| EE | 15.03.2017 | ||
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| NL | 15.03.2017 | ||
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| RO | 15.03.2017 | ||
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| SI | 15.03.2017 | ||
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| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| IE | 19.11.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| BE | 30.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2019/46] | HU | 19.11.2010 | |
| AT | 15.03.2017 | ||
| CY | 15.03.2017 | ||
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
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| FI | 15.03.2017 | ||
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| LT | 15.03.2017 | ||
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| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
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| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| IE | 19.11.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| BE | 30.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2019/31] | HU | 19.11.2010 | |
| AT | 15.03.2017 | ||
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| MC | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| IE | 19.11.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| BE | 30.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2018/50] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| MC | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| IE | 19.11.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| BE | 30.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2018/45] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| MC | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| IE | 19.11.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2018/43] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| MC | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| LU | 19.11.2017 | ||
| MT | 19.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2018/41] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| MC | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| LU | 19.11.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2018/33] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| MC | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| CH | 30.11.2017 | ||
| LI | 30.11.2017 | ||
| Former [2018/14] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SI | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| Former [2018/09] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| DK | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| Former [2017/51] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| SM | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| PT | 17.07.2017 | ||
| Former [2017/50] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| PL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| Former [2017/49] | AT | 15.03.2017 | |
| CZ | 15.03.2017 | ||
| EE | 15.03.2017 | ||
| ES | 15.03.2017 | ||
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| IT | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| RO | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| SK | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| IS | 15.07.2017 | ||
| Former [2017/48] | CZ | 15.03.2017 | |
| FI | 15.03.2017 | ||
| HR | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | ||
| Former [2017/41] | FI | 15.03.2017 | |
| HR | 15.03.2017 | ||
| LT | 15.03.2017 | ||
| LV | 15.03.2017 | ||
| NL | 15.03.2017 | ||
| RS | 15.03.2017 | ||
| SE | 15.03.2017 | ||
| BG | 15.06.2017 | ||
| NO | 15.06.2017 | ||
| GR | 16.06.2017 | Cited in | by applicant | US26403810 | JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, 2010, pages 4412 - 4421 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, 2009, pages 5486 - 5489 | PURE APPLI. CHEM., vol. 45, 1976, pages 11 - 13 | "Handbook of Pharmaceutical Salts", 2002, VERLAG HELVETICA CHEMICA ACTA- ZURICH, pages: 329 - 345 | HALE, J. ET AL., BIOORG. & MED. CHEM. LETT., vol. 14, 2004, pages 3351 |