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Extract from the Register of European Patents

EP About this file: EP2438046

EP2438046 - O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.04.2018
Database last updated on 16.07.2024
FormerExamination is in progress
Status updated on  20.12.2016
Most recent event   Tooltip13.04.2018Application deemed to be withdrawnpublished on 16.05.2018  [2018/20]
Applicant(s)For all designated states
President and Fellows of Harvard College
17 Quincy Street
Cambridge, MA 02138 / US
[2012/15]
Inventor(s)01 / WALKER KAHNE, Suzanne
14 Corey Road
Brookline, MA 02445 / US
02 / LAZARUS, Michael, Block
130 Berkeley Street
W. Newton, MA 02465 / US
03 / GROSS, Benjamin, J.
1318 Waverly Road
Gladwyne, PA 19035 / US
 [2012/15]
Representative(s)Crooks, Elizabeth Caroline, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2012/15]Crooks, Elizabeth Caroline, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date10783701.501.06.2010
WO2010US01596
Priority number, dateUS20090217514P01.06.2009         Original published format: US 217514 P
[2012/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010141074
Date:09.12.2010
Language:EN
[2010/49]
Type: A2 Application without search report 
No.:EP2438046
Date:11.04.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 09.12.2010 takes the place of the publication of the European patent application.
[2012/15]
Search report(s)International search report - published on:KR31.03.2011
(Supplementary) European search report - dispatched on:EP20.03.2013
ClassificationIPC:C07D215/04, C07D401/12, C07D215/36, C07D405/12, C07D409/14, C07D417/12, A61K31/4704, A61P3/10
[2013/11]
CPC:
C07D417/12 (EP,US); A61P1/04 (EP); A61P1/16 (EP);
A61P11/00 (EP); A61P13/08 (EP); A61P13/10 (EP);
A61P13/12 (EP); A61P15/00 (EP); A61P17/00 (EP);
A61P17/06 (EP); A61P17/14 (EP); A61P19/02 (EP);
A61P21/00 (EP); A61P21/04 (EP); A61P25/00 (EP);
A61P25/02 (EP); A61P25/28 (EP); A61P27/02 (EP);
A61P27/16 (EP); A61P29/00 (EP); A61P3/00 (EP);
A61P3/10 (EP); A61P31/04 (EP); A61P31/12 (EP);
A61P35/00 (EP); A61P35/02 (EP); A61P37/00 (EP);
A61P43/00 (EP); A61P5/14 (EP); A61P7/00 (EP);
A61P7/06 (EP); A61P9/00 (EP); C07D215/36 (EP,US);
C07D401/12 (EP,US); C07D405/12 (EP,US); C07D409/14 (EP,US) (-)
Former IPC [2012/15]C07D215/04, C07D401/12, A61K31/4704, A61P3/10
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/15]
TitleGerman:O-GLCNAC-TRANSFERASEHEMMER UND VERWENDUNGEN DAVON[2012/15]
English:O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF[2012/15]
French:INHIBITEURS DE LA O-GLCNAC TRANSFÉRASE ET LEURS UTILISATIONS[2012/15]
Entry into regional phase21.12.2011National basic fee paid 
21.12.2011Search fee paid 
21.12.2011Designation fee(s) paid 
21.12.2011Examination fee paid 
Examination procedure21.12.2011Examination requested  [2012/15]
03.08.2012Loss of particular rights, legal effect: Claims
10.09.2012Despatch of communication of loss of particular rights: Claims {1}
10.02.2014Amendment by applicant (claims and/or description)
14.10.2015Despatch of a communication from the examining division (Time limit: M06)
22.04.2016Reply to a communication from the examining division
12.08.2016Invitation to indicate the basis for amendments (Time limit: M01)
09.09.2016Reply to an invitation to indicate the basis for amendments
09.12.2016Despatch of a communication from the examining division (Time limit: M04)
19.04.2017Reply to a communication from the examining division
31.05.2017Despatch of a communication from the examining division (Time limit: M06)
12.12.2017Application deemed to be withdrawn, date of legal effect  [2018/20]
10.01.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2018/20]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.10.2015
Request for further processing for:The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application
10.02.2014Request for further processing filed
10.02.2014Full payment received (date of receipt of payment)
Request granted
16.04.2014Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
10.02.2014Request for further processing filed
10.02.2014Full payment received (date of receipt of payment)
Request granted
16.04.2014Decision despatched
Fees paidRenewal fee
26.06.2012Renewal fee patent year 03
20.12.2013Renewal fee patent year 04
30.06.2014Renewal fee patent year 05
29.06.2015Renewal fee patent year 06
27.06.2016Renewal fee patent year 07
27.06.2017Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
30.06.201304   M06   Fee paid on   20.12.2013
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Documents cited:Search[X]WO2007120638  (HARVARD COLLEGE [US], et al) [X] 1,2,6-8 * pages 16,17; claim 1; compound 9 *;
 [X]WO2009036341  (UNIV MICHIGAN [US], et al) [X] 1,2,6-8 * page 84 *;
 [X]  - ANNA MARIA ALMERICO ET AL, "In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators", JOURNAL OF MOLECULAR MODELING, SPRINGER VERLAG, DE, (20081206), vol. 15, no. 4, ISSN 0948-5023, pages 349 - 355, XP019724180 [X] 1,2,6-8 * compound 16 *

DOI:   http://dx.doi.org/10.1007/s00894-008-0405-x
 [X]  - ANNA L BOWMAN ET AL, "Small Molecule Inhibitors of the MDM2-p53 Interaction Discovered by Ensemble-Based Receptor Models", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ACS PUBLICATIONS, US, vol. 129, no. 42, doi:10.1021/JA073687X, ISSN 0002-7863, (20071024), pages 12809 - 12814, (20070929), XP008148630 [X] 1,2,6-8 * p. S7 (suppl. inf.) *

DOI:   http://dx.doi.org/10.1021/ja073687x
 [X]  - "Benzenepropanamide, N-(2-chlorophenyl)-.alpha.-[[(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)sulfonyl]amino]-, (.alpha.S)-", REGISTRY, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (20090121), Database accession no. 1094798-35-2, XP002691454 [X] 5 * the whole document *
International search[X]WO2007120638  (HARVARD COLLEGE [US], et al);
 [X]WO2009036341  (UNIV MICHIGAN [US], et al);
 [X]  - ALMERICO, A.M. ET AL., "In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators.", JOURNAL OF MOLECULAR MODELING., (2009), vol. 15, no. 4, pages 349 - 355, XP019724180

DOI:   http://dx.doi.org/10.1007/s00894-008-0405-x
 [X]  - BOWMAN, A.L. ET AL., "Small molecule inhibitors of the MDM2-p53 interaction discovered by ensemble-based receptor models.", JOURNAL OF AMERICAN CHEMICAL SOCIETY, (2007), vol. 129, no. 42, pages 12809 - 12814, XP008148630

DOI:   http://dx.doi.org/10.1021/ja073687x
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.