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Extract from the Register of European Patents

EP About this file: EP2515922

EP2515922 - PLANT EXTRACT FOR TREATING NEURODEGENERATIVE ILLNESSES [Right-click to bookmark this link]
Former [2012/44]PLANT EXTRACTS FOR TREATING NEURODEGENERATIVE DISEASES
[2013/17]
StatusNo opposition filed within time limit
Status updated on  08.08.2014
Database last updated on 16.09.2024
Most recent event   Tooltip13.03.2020Change - lapse in a contracting state
State(s) deleted from list of lapses: TR		published on 15.04.2020  [2020/16]
Applicant(s)For all designated states
Finzelberg GmbH & Co. KG
Koblenzer Strasse 48-56
56626 Andernach / DE
[2012/44]
Inventor(s)01 / WALBROEL, Bernd
Flurgasse 48
53639 Königswinter / DE
02 / FEISTEL, Björn
Im Boden 32
56626 Andernach / DE
03 / PAHNKE, Jens
Zum Fuchsbau 6
18147 Rostock / DE
 [2011/33]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[N/P]
Former [2012/44]von Kreisler Selting Werner
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
Application number, filing date10800741.022.12.2010
WO2010EP70531
Priority number, dateEP2009018062723.12.2009         Original published format: EP 09180627
[2011/33]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report
No.:WO2011076867
Date:30.06.2011
Language:DE
[2011/26]
Type: A2 Application without search report 
No.:EP2515922
Date:31.10.2012
Language:DE
The application published by WIPO in one of the EPO official languages on 30.06.2011 takes the place of the publication of the European patent application.
[2012/44]
Type: B1 Patent specification 
No.:EP2515922
Date:02.10.2013
Language:DE
[2013/40]
Search report(s)International search report - published on:EP18.08.2011
ClassificationIPC:A61K36/53, A61P25/28
[2012/44]
CPC:
A61K36/53 (EP,US); A61K36/00 (EP,US); A61K36/38 (EP,US);
A61P25/00 (EP); A61P25/28 (EP)
Former IPC [2011/33]A61K36/53
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/44]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PFLANZENEXTRAKTE ZUR BEHANDLUNG VON NEURODEGENERATIVEN ERKRANKUNGEN[2012/44]
English:PLANT EXTRACT FOR TREATING NEURODEGENERATIVE ILLNESSES[2013/20]
French:EXTRAITS DE PLANTES DESTINÉS AU TRAITEMENT DE MALADIES NEURODÉGÉNÉRATIVES[2013/20]
Former [2012/44]PLANT EXTRACTS FOR TREATING NEURODEGENERATIVE DISEASES
Former [2012/44]EXTRAITS VÉGÉTAUX POUR LE TRAITEMENT DE MALADIES NEURODÉGÉNÉRATIVES
Entry into regional phase05.07.2012National basic fee paid 
05.07.2012Designation fee(s) paid 
05.07.2012Examination fee paid 
Examination procedure06.10.2011Request for preliminary examination filed
International Preliminary Examining Authority: EP
05.07.2012Examination requested  [2012/44]
31.08.2012Amendment by applicant (claims and/or description)
16.04.2013Communication of intention to grant the patent
18.07.2013Fee for grant paid
18.07.2013Fee for publishing/printing paid
24.07.2013Observations by third parties
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.04.2013
Opposition(s)03.07.2014No opposition filed within time limit [2014/37]
Fees paidRenewal fee
19.12.2012Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.12.2010
AL02.10.2013
BG02.10.2013
CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
MT02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO01.01.2014
IS02.02.2014
[2020/16]
Former [2020/15]HU22.12.2010
AL02.10.2013
BG02.10.2013
CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
MT02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
TR02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO01.01.2014
IS02.02.2014
Former [2018/46]HU22.12.2010
AL02.10.2013
BG02.10.2013
CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
MT02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO01.01.2014
IS02.02.2014
Former [2016/21]HU22.12.2010
BG02.10.2013
CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
MT02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO01.01.2014
IS02.02.2014
Former [2015/41]HU22.12.2010
BG02.10.2013
CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
MT02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2015/34]HU22.12.2010
BG02.10.2013
CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2015/33]CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MK02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2015/25]CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
SM02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2015/21]CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2014/48]CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
IE22.12.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2014/46]CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
LU22.12.2013
BE31.12.2013
NO02.01.2014
IS02.02.2014
Former [2014/41]CY02.10.2013
DK02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
LU22.12.2013
NO02.01.2014
IS02.02.2014
Former [2014/38]CY02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
LU22.12.2013
NO02.01.2014
IS02.02.2014
Former [2014/37]CY02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RO02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
LU22.12.2013
NO02.01.2014
IS02.02.2014
Former [2014/36]CY02.10.2013
EE02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/26]CY02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/25]FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/24]FI02.10.2013
HR02.10.2013
LT02.10.2013
NL02.10.2013
RS02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/23]FI02.10.2013
HR02.10.2013
LT02.10.2013
NL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/22]FI02.10.2013
LT02.10.2013
NL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
Former [2014/20]LT02.10.2013
SI02.10.2013
NO02.01.2014
Former [2014/12]SI02.10.2013
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by applicantEP1054682
    - R. BROOKMEYER, "Forecasting the global burden of Alzheimer's disease", ALZHEIMER'S AND DEMENTIA, (200703), vol. 3, pages 186 - 191
    - CORDER, E.H. ET AL., "Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families", SCIENCE, (1993), vol. 261, no. 5123, pages 921 - 923
    - BU, G., "Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy", NAT. REV. NEUROSCI., (2009), vol. 10, no. 5, pages 333 - 344
    - CURRENT ALZHEIMER RESEARCH, vol. 5, pages 396 - 406
    - PAHNKE ET AL., "Alzheimer's disease and blood-brain barrier function - Why have anti-ß-amyloid therapies failed to prevent dementia progression?", NEUROSCIBIOBEHAVR, (2009), vol. 33, pages 1099 - 1108
    - DEKOSKY ET AL., "Ginkgo biloba for Prevention of Dementia: A Randomized Controlled Trial", JAMA, (2008), vol. 300, no. 19, pages 2253 - 2262
    - SILVA ET AL., NEUROTOXICITY RESEARCH, (2004), vol. 6, no. 2, pages 119 - 130
    - JOHNE ET AL., BGBL, (2003), vol. 46, pages 1061 - 1067
    - MOORE ET AL., "St.John's wort induces hepatic drug metabolism through activation of the pregnane X receptor", PROC NATL ACAD SCI USA, (2000), vol. 97, pages 7500 - 7502
    - PAHNKE ET AL., "Clinico-pathological function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease", CURRENT ALZHEIMER RESEARCH, (2008), vol. 5, pages 396 - 406
    - OAKLEY H. ET AL., "Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation", J NEUROSCI, (2006), vol. 26, no. 40, pages 10129 - 40
    - SILVA, B. ET AL., NEUROTOXICITY RESEARCH, (2004), pages 119 - 130
other   - CHOW T.W. ET AL, "Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease.", NEUROPSYCHIATRIC DISEASE AND TREATMENT, (2007), vol. 3, no. 5, pages 627 - 636, XP055073186
    - LEHR T. ET AL, "Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease.", BR J CLIN PHARMACOL, (20070223), vol. 64, no. 1, pages 36 - 48, XP055073189

DOI:   http://dx.doi.org/10.1111/j.1365-2125.2007.02855.x
    - MARKS D.M. ET AL, "Triple reuptake inhibitors: A premise and promise.", PSYCHIATRY INVEST, (2008), vol. 5, pages 142 - 147, XP055073197

DOI:   http://dx.doi.org/10.4306/pi.2008.5.3.142
    - NITSCH R.M. ET AL, "SEROTONIN 5-HT2A AND 5-HT2C RECEPTORS STIMULATE AMYLOID PRECURSOR PROTEIN ECTODOMAIN SECRETION.", JOURNAL OF BIOLOGICAL CHEMISTRY, (19960223), vol. 271, no. 8, pages 4188 - 4194, XP001149842

DOI:   http://dx.doi.org/10.1074/jbc.271.8.4188
    - PAKASKI M.ET AL, "Imipramine and citalopram facilitate amyloid precursor protein secretion in vitro.", NEUROCHEMISTRY INTERNATIONAL, (2005), vol. 47, pages 190 - 195, XP027856727
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