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Extract from the Register of European Patents

EP About this file: EP2519814

EP2519814 - METHOD FOR THE COMPARATIVE ANALYSIS OF PROTEIN PREPARATIONS BY MEANS OF NUCLEAR MAGNETIC RESONANCE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  08.11.2013
Database last updated on 07.10.2024
Most recent event   Tooltip08.11.2013Application deemed to be withdrawnpublished on 11.12.2013  [2013/50]
Applicant(s)For all designated states
C.E.R.B.M.
Parc d'Innovation 1 rue Laurent Fries B.P. 10142
67400 Illkirch Graffenstaden / FR
For all designated states
NMRTEC
Bioparc Boulevard Sébastien Brandt
67400 Illkirch Graffenstaden / FR
For all designated states
Université de Strasbourg
4, rue Blaise Pascal
67000 Strasbourg / FR
[N/P]
Former [2012/45]For all designated states
C.E.R.B.M.
Parc d'Innovation 1 rue Laurent Fries B.P. 10142
67400 Illkirch Graffenstaden / FR
For all designated states
NMRTEC
Bioparc Boulevard Sébastien Brandt
67400 Illkirch Graffenstaden / FR
For all designated states
Université de Strasbourg
4, rue Blaise Pascal
67000 Strasbourg / FR
Inventor(s)01 / STARCK, Jean-Philippe
12 rue des Tilleuls
F-67270 Gougenheim / FR
02 / KIEFFER, Bruno
7 rue Henri Heine
F-67100 Strasbourg / FR
03 / QUINTERNET, Marc
7 rue des Pâquis
54220 Malzeville / FR
 [2012/45]
Representative(s)Barny, Luc
Cabinet Barny
52, avenue des Vosges
67000 Strasbourg / FR
[2012/45]
Application number, filing date10812874.530.12.2010
WO2010FR52936
Priority number, dateFR2009000642731.12.2009         Original published format: FR 0906427
[2012/45]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2011080492
Date:07.07.2011
Language:FR
[2011/27]
Type: A1 Application with search report 
No.:EP2519814
Date:07.11.2012
Language:FR
The application published by WIPO in one of the EPO official languages on 07.07.2011 takes the place of the publication of the European patent application.
[2012/45]
Search report(s)International search report - published on:EP07.07.2011
ClassificationIPC:G01N24/08, G01R33/46, G01R33/465
[2012/45]
CPC:
G01R33/465 (EP,US); G01N24/08 (EP,US); G01N24/087 (EP,US);
G01R33/4633 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/45]
TitleGerman:VERFAHREN ZUR VERGLEICHENDEN ANALYSE VON PROTEINZUBREITUNGEN MITTELS KERNMAGNETRESONANZ[2012/45]
English:METHOD FOR THE COMPARATIVE ANALYSIS OF PROTEIN PREPARATIONS BY MEANS OF NUCLEAR MAGNETIC RESONANCE[2012/45]
French:METHODE D'ANALYSE COMPARATIVE DE PREPARATIONS PROTEIQUES PAR RESONANCE MAGNETIQUE NUCLEAIRE[2012/45]
Entry into regional phase31.07.2012National basic fee paid 
31.07.2012Designation fee(s) paid 
31.07.2012Examination fee paid 
Examination procedure26.07.2012Amendment by applicant (claims and/or description)
31.07.2012Examination requested  [2012/45]
02.07.2013Application deemed to be withdrawn, date of legal effect  [2013/50]
02.08.2013Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2013/50]
Fees paidPenalty fee
Additional fee for renewal fee
31.12.201203   M06   Not yet paid
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[AD]EP0975954  (ABBOTT LAB [US]) [AD] 1-7,9,10 * the whole document *;
 [XI]  - AUBIN Y ET AL, "Assessment of the three-dimensional structure of recombinant protein therapeutics by NMR fingerprinting: Demonstration on recombinant human granulocyte macrophage-colony stimulation factor", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20080401), vol. 80, no. 7, doi:DOI:10.1021/AC7026222, ISSN 0003-2700, pages 2623 - 2627, XP007918475 [X] 1-7,10 * page 2623 - page 2625; figures 1,2 * [I] 9

DOI:   http://dx.doi.org/10.1021/ac7026222
 [L]  - SAUVÉ SIMON ET AL, "NMR assignment of human granulocyte-macrophage colony-stimulating factor", BIOMOLECULAR NMR ASSIGNMENTS, SPRINGER, NL, vol. 2, no. 1, ISSN 1874-2718, (20080601), pages 5 - 7, (20071208), XP007918476 [L] 1-7,9,10 * the whole document * * Ce document complète la divulgation de la méthode du document XP007918475, qui cite explicitement le document XP007918476. *
 [XI]  - BOCIAN WOJCIECH ET AL, "Direct insight into insulin aggregation by 2D NMR complemented by PFGSE NMR", PROTEINS: STRUCTURE, FUNCTION AND GENETICS, JOHN WILEY & SONS, INC, US LNKD- DOI:10.1002/PROT.21969, (20080515), vol. 71, no. 3, ISSN 0887-3585, pages 1057 - 1065, XP007914270 [X] 1-7,9 * abstract * * page 1058, column 1, paragraph 2 - page 1059, column 1, paragraph 3; figures 3,4 * [I] 10

DOI:   http://dx.doi.org/10.1002/prot.21969
 [XI]  - AGRAWAL P ET AL, "Solution studies on the complex of 4'-epiadriamycin-d-(CGATCG)2 followed by time-resolved fluorescence measurement, diffusion ordered spectroscopy and restrained molecular dynamics simulations", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB LNKD- DOI:10.1016/J.BMC.2009.02.032, vol. 17, no. 7, ISSN 0968-0896, (20090401), pages 2793 - 2811, (20090224), XP026073630 [X] 1-7 * page 2794; figures 2-4; tables 1a,1b * * page 2801; figure 7 * * page 2809 - page 2810 * [I] 9,10

DOI:   http://dx.doi.org/10.1016/j.bmc.2009.02.032
 [XPI]  - PANJWANI N ET AL, "Assessment of the effects of pH, formulation and deformulation on the conformation of interferon alpha-2 by NMR", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, (20100223), vol. 99, no. 8, doi:DOI:10.1002/JPS.22105, ISSN 0022-3549, pages 3334 - 3342, XP007918517 [XP] 1-7 * page 3334 - page 3340; figures 1,2,3 * [I] 9,10

DOI:   http://dx.doi.org/10.1002/jps.22105
 [I]  - GOGER M ET AL, "Molecular insights into PEBP2/CBF[beta]-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF[beta]", NATURE STRUCTURAL BIOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (19990101), vol. 6, no. 7, ISSN 1072-8368, pages 620 - 623, XP007914200 [I] 1-7,9,10 * page 620, column 2; figure 2 * * page 623, column 1 *
 [I]  - MARKUS ZEEB ET AL, "Recognition of T-rich single-stranded DNA by the cold shock protein Bs-CspB in solution", NUCLEIC ACIDS RESEARCH, vol. 34, no. 16, ISSN 0305-1048, (20060901), pages 4561 - 4571, (20060901), XP007914178 [I] 1-7,9,10 * page 2 - page 8; figures 1,4 *

DOI:   http://dx.doi.org/10.1093/nar/gkl376
 [I]  - ABDULAEV N G ET AL, "Heterotrimeric G-protein [alpha]-subunit adopts a preactivated conformation when associated with [beta][gamma]-subunits", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, no. 45, ISSN 0021-9258, (20050829), pages 38071 - 38080, (20051111), XP007914180 [I] 1-7,9,10 * page 38072, column 2, paragraph 3 - page 38075; figures 4,5 *

DOI:   http://dx.doi.org/10.1074/jbc.M505259200
 [I]  - WAGNER G ET AL, "SYSTEMATIC APPLICATION OF 2 DIMENSIONAL PROTON NMR TECHNIQUES FOR STUDIES OF PROTEINS 2. COMBINED USE OF CORRELATED SPECTROSCOPY AND NUCLEAR OVERHAUSER SPECTROSCOPY FOR SEQUENTIAL ASSIGNMENTS OF BACKBONE RESONANCES AND ELUCIDATION OF POLY PEPTIDE SECONDARY STRUCTURES", EUROPEAN JOURNAL OF BIOCHEMISTRY, BLACKWELL PUBLISHING, BERLIN, DE, (19810101), vol. 114, no. 2, ISSN 0014-2956, pages 375 - 384, XP007914199 [I] 1-7,9,10 * page 375 - page 379; figures 1-3,5-8,10 *
 [AD]  - SATTLER M ET AL, "Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients", PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, PERGAMON PRESS, OXFORD, GB, (19990319), vol. 34, no. 2, ISSN 0079-6565, pages 93 - 158, XP007914139 [AD] 1-7,9,10 * pages 95,146; table 1 * * page 154 *
 [AD]  - SCHANDA P ET AL, "Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, NEW YORK, US LNKD- DOI:10.1021/JA051306E, (20050608), vol. 127, no. 22, ISSN 0002-7863, pages 8014 - 8015, XP007914137 [AD] 1-7,9,10 * the whole document *

DOI:   http://dx.doi.org/10.1021/ja051306e
 [AD]  - BALAYSSAC S ET AL, "Two-dimensional DOSY experiment with Excitation Sculpting water suppression for the analysis of natural and biological media", JOURNAL OF MAGNETIC RESONANCE, ACADEMIC PRESS, ORLANDO, FL, US LNKD- DOI:10.1016/J.JMR.2008.09.022, vol. 196, no. 1, ISSN 1090-7807, (20090101), pages 78 - 83, (20080930), XP025746052 [AD] 1-7,9,10 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jmr.2008.09.022
 [AD]  - CHANG X ET AL, "Solution structures of the R6 human insulin hexamer", BIOCHEMISTRY, vol. 36, no. 31, ISSN 0006-2960, (19970805), pages 9409 - 9422, (19970805), XP007914160 [AD] 1-7,9,10 * the whole document *

DOI:   http://dx.doi.org/10.1021/bi9631069
by applicantEP0975954
 WO2008128219
    - SATTLER ET AL., PROG NUE MAG RESON SPECTRO, (1999), vol. 34, no. 2, pages 93 - 158
    - C.S. JOHNSON JR., "Diffusion ordered nuclear magnetic resonance spectroscopy: principles and applications", PROG. NMR SPECTROSC., (1999), vol. 34, doi:doi:10.1016/S0079-6565(99)00003-5, pages 203 - 256, XP002216416

DOI:   http://dx.doi.org/10.1016/S0079-6565(99)00003-5
    - BALAYSSAC S. ET AL., J. MAGN. RESON., (2009), vol. 196, pages 78 - 83
    - SCHANDA ET AL., J AM CHEM SOC, (2005), vol. 127, no. 22, pages 8014 - 15
    - Biochimie Générale, page 17
    - CHANG X. ET AL., BIOCHEMISTRY, (1997), vol. 36, pages 9409 - 9422
    - SCHANDA P. ET AL., J. BIOMOL. NMR, (2005), vol. 33, pages 199 - 211
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.