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Extract from the Register of European Patents

EP About this file: EP2501803

EP2501803 - METHODS OF ENHANCING PLURIPOTENTCY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.10.2021
Database last updated on 28.05.2024
FormerThe patent has been granted
Status updated on  20.11.2020
FormerGrant of patent is intended
Status updated on  23.06.2020
FormerExamination is in progress
Status updated on  23.11.2016
Most recent event   Tooltip27.04.2024Lapse of the patent in a contracting state
New state(s): MK
published on 29.05.2024 [2024/22]
Applicant(s)For all designated states
Agency for Science, Technology and Research
1 Fusionopolis Way 20-10 Connexis
Singapore 138632 / SG
[2012/39]
Inventor(s)01 / LIM, Bing
Genome Institute of Singapore
60 Biopolis Street
Genome 08-01
Singapore 138672 / SG
02 / HAN, Jianyong
Genome Institute of Singapore
60 Biopolis Street
Genome 08-01
Singapore138672 / SG
03 / TAM, Wai-Leong
Genome Institute of Singapore
60 Biopolis Street
Genome 08-01
Singapore 138672 / SG
 [2013/15]
Former [2012/39]01 / LIM Bing
Genome Institute of Singapore
60 Biopolis Street
Genome 08-01
Singapore 138672 / SG
02 / HAN Jianyong
Genome Institute of Singapore
60 Biopolis Street
Genome 08-01
Singapore138672 / SG
03 / TAM Wai-Leong
Genome Institute of Singapore
60 Biopolis Street
Genome 08-01
Singapore 138672 / SG
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[2020/52]
Former [2013/51]Boult Wade Tennant
Verulam Gardens
70 Gray's Inn Road
London WC1X 8BT / GB
Former [2012/39]Spencer, Matthew Peter, et al
Boult Wade Tennant Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT / GB
Application number, filing date10831883.318.11.2010
[2020/52]
WO2010SG00437
Priority number, dateSG2010000082506.02.2010         Original published format: SG 201000825
US20090262741P19.11.2009         Original published format: US 262741 P
[2012/39]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011062559
Date:26.05.2011
Language:EN
[2011/21]
Type: A1 Application with search report 
No.:EP2501803
Date:26.09.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 26.05.2011 takes the place of the publication of the European patent application.
[2012/39]
Type: B1 Patent specification 
No.:EP2501803
Date:23.12.2020
Language:EN
[2020/52]
Search report(s)International search report - published on:AU26.05.2011
(Supplementary) European search report - dispatched on:EP04.07.2013
ClassificationIPC:C12N5/0789, C12N5/071, C12N5/10
[2012/39]
CPC:
C12N5/0696 (EP,US); A01K67/0271 (EP,US); A61P43/00 (EP);
C12N15/00 (EP,US); C12N15/873 (EP,US); C12N2501/00 (US);
C12N2501/60 (EP,US); C12N2501/602 (EP,US); C12N2501/603 (EP,US);
C12N2501/604 (EP,US); C12N2506/00 (US); C12N2510/00 (EP,US);
C12N2799/027 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/39]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUR PLURIPOTENZINTENSIVIERUNG[2012/39]
English:METHODS OF ENHANCING PLURIPOTENTCY[2012/39]
French:MÉTHODES PERMETTANT D'AUGMENTER LA PLURIPOTENCE[2012/39]
Entry into regional phase15.06.2012National basic fee paid 
15.06.2012Search fee paid 
15.06.2012Designation fee(s) paid 
15.06.2012Examination fee paid 
Examination procedure26.08.2011Request for preliminary examination filed
International Preliminary Examining Authority: AU
15.06.2012Examination requested  [2012/39]
10.02.2014Despatch of a communication from the examining division (Time limit: M04)
20.06.2014Reply to a communication from the examining division
16.12.2014Despatch of a communication from the examining division (Time limit: M04)
22.04.2015Reply to a communication from the examining division
15.07.2016Despatch of a communication from the examining division (Time limit: M04)
22.11.2016Reply to a communication from the examining division
21.06.2017Despatch of a communication from the examining division (Time limit: M06)
30.11.2017Reply to a communication from the examining division
31.07.2018Despatch of a communication from the examining division (Time limit: M04)
27.09.2018Reply to a communication from the examining division
22.01.2019Despatch of a communication from the examining division (Time limit: M04)
23.05.2019Reply to a communication from the examining division
24.06.2020Communication of intention to grant the patent
26.10.2020Fee for grant paid
26.10.2020Fee for publishing/printing paid
26.10.2020Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  10.02.2014
Opposition(s)24.09.2021No opposition filed within time limit [2021/48]
Fees paidRenewal fee
23.11.2012Renewal fee patent year 03
25.11.2013Renewal fee patent year 04
21.11.2014Renewal fee patent year 05
23.11.2015Renewal fee patent year 06
24.11.2016Renewal fee patent year 07
23.11.2017Renewal fee patent year 08
23.11.2018Renewal fee patent year 09
22.11.2019Renewal fee patent year 10
16.11.2020Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.11.2010
AL23.12.2020
AT23.12.2020
CY23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
MC23.12.2020
MK23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SI23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
[2024/22]
Former [2023/29]HU18.11.2010
AL23.12.2020
AT23.12.2020
CY23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
MC23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SI23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2023/24]AL23.12.2020
AT23.12.2020
CY23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
MC23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SI23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2022/33]AL23.12.2020
AT23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
MC23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SI23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2022/23]AL23.12.2020
AT23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SI23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2022/13]AL23.12.2020
AT23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SI23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2022/10]AL23.12.2020
AT23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/51]AL23.12.2020
AT23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
ES23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2021/49]AL23.12.2020
AT23.12.2020
CZ23.12.2020
DK23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2021/48]AL23.12.2020
AT23.12.2020
CZ23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
IT23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2021/45]AL23.12.2020
AT23.12.2020
CZ23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2021/42]AT23.12.2020
CZ23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
IS23.04.2021
PT23.04.2021
Former [2021/39]AT23.12.2020
CZ23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
PL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/37]AT23.12.2020
CZ23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/36]CZ23.12.2020
EE23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/35]CZ23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
RO23.12.2020
RS23.12.2020
SE23.12.2020
SK23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/34]CZ23.12.2020
FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
RS23.12.2020
SE23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/33]FI23.12.2020
HR23.12.2020
LT23.12.2020
LV23.12.2020
NL23.12.2020
RS23.12.2020
SE23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
PT23.04.2021
Former [2021/32]FI23.12.2020
HR23.12.2020
LV23.12.2020
NL23.12.2020
RS23.12.2020
SE23.12.2020
SM23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
Former [2021/30]FI23.12.2020
HR23.12.2020
LV23.12.2020
NL23.12.2020
RS23.12.2020
SE23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
Former [2021/28]FI23.12.2020
HR23.12.2020
LV23.12.2020
RS23.12.2020
SE23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
Former [2021/24]FI23.12.2020
LV23.12.2020
RS23.12.2020
SE23.12.2020
BG23.03.2021
NO23.03.2021
GR24.03.2021
Former [2021/23]FI23.12.2020
LV23.12.2020
RS23.12.2020
SE23.12.2020
NO23.03.2021
GR24.03.2021
Former [2021/22]FI23.12.2020
RS23.12.2020
NO23.03.2021
Former [2021/20]FI23.12.2020
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DOI:   http://dx.doi.org/10.1186/gb-2006-7-8-230)
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DOI:   http://dx.doi.org/10.1161/CIRCRESAHA.107.169565
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DOI:   http://dx.doi.org/10.1101/sqb.2010.75.003
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 [X]  - GENBANK, (20040517), Database accession no. NM_016569.3
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DOI:   http://dx.doi.org/10.1038/nature08735
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DOI:   http://dx.doi.org/10.1186/scrt12
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DOI:   http://dx.doi.org/10.1038/nature08113
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DOI:   http://dx.doi.org/10.1002/(SICI)1097-0177(199608)206:4<379::AID-AJA4>3.0.CO;2-F
    - ZHANG, J. ET AL., "Sa114 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5fl", NAT CELL BIOL, (2006), vol. 8, doi:doi:10.1038/ncb1481, pages 1114 - 23, XP055092517

DOI:   http://dx.doi.org/10.1038/ncb1481
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DOI:   http://dx.doi.org/10.1038/ng1760
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