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Extract from the Register of European Patents

EP About this file: EP2467136

EP2467136 - 4-METHYLPYRAZOLE FORMULATIONS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.03.2015
Database last updated on 07.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Raptor Therapeutics Inc.
7 Hamilton Landing, Suite 100
Novato, CA 94949 / US
[2014/38]
Former [2014/19]For all designated states
Raptor Therapeutics Inc.
5 Hamilton Landing, Suite 160
Novato, CA 94949 / US
Former [2012/26]For all designated states
Raptor Therapeutics Inc.
9 Commercial Boulevard, Suite 200
Novato, CA 94949 / US
Inventor(s)01 / DALEY, Thomas, E.
536 E. Hillsdale
San Mateo CA 94403 / US
02 / POWELL, Kathy
100 Oxyard Way
Cary NC 27519 / US
03 / JARZEBINSKI, Olga
9357 Carriage Run Circle
Loveland OH 45140 / US
 [2012/26]
Representative(s)O'Brien, Lisa, et al
Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2014/13]Kiernan, Lisa, et al
Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
Former [2013/52]Savic, Bojan, et al
Jones Day
Rechtsanwälte Attorneys-at-Law Patentanwälte
Prinzregentenstraße 11
80538 München / DE
Former [2012/26]Ritter, Thomas Kurt, et al
Jones Day
Prinzregentenstraße 11
D-80538 München / DE
Application number, filing date10836472.006.12.2010
WO2010US59065
Priority number, dateUS20090267389P07.12.2009         Original published format: US 267389 P
[2012/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011071805
Date:16.06.2011
Language:EN
[2011/24]
Type: A1 Application with search report 
No.:EP2467136
Date:27.06.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 16.06.2011 takes the place of the publication of the European patent application.
[2012/26]
Type: B1 Patent specification 
No.:EP2467136
Date:07.05.2014
Language:EN
[2014/19]
Search report(s)International search report - published on:US16.06.2011
(Supplementary) European search report - dispatched on:EP18.12.2012
ClassificationIPC:A61K31/415, A61P25/32, A61K9/48
[2013/03]
CPC:
A61K31/415 (EP,KR,US); A61K9/0053 (US); A61K9/4825 (US);
A61K9/4858 (EP,US); A61K9/4866 (US); A61P25/32 (EP);
A61P3/00 (EP); A61P43/00 (EP) (-)
Former IPC [2012/26]A61K31/415, A61P25/32
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/26]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:4-METHYLPYRAZOL-FORMULIERUNGEN[2012/26]
English:4-METHYLPYRAZOLE FORMULATIONS[2012/26]
French:FORMULATIONS DE 4-MÉTHYLPYRAZOLE[2012/26]
Entry into regional phase14.03.2012National basic fee paid 
14.03.2012Search fee paid 
14.03.2012Designation fee(s) paid 
14.03.2012Examination fee paid 
Examination procedure14.03.2012Examination requested  [2012/26]
04.07.2013Amendment by applicant (claims and/or description)
30.08.2013Despatch of a communication from the examining division (Time limit: M04)
29.10.2013Reply to a communication from the examining division
27.11.2013Communication of intention to grant the patent
21.03.2014Fee for grant paid
21.03.2014Fee for publishing/printing paid
Divisional application(s)EP14150138.7  / EP2774612
EP17187679.0  / EP3300732
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  30.08.2013
Opposition(s)10.02.2015No opposition filed within time limit [2015/16]
Fees paidRenewal fee
28.12.2012Renewal fee patent year 03
12.12.2013Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU06.12.2010
AL07.05.2014
BG07.05.2014
CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MK07.05.2014
MT07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
[2018/46]
Former [2018/30]HU06.12.2010
BG07.05.2014
CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MK07.05.2014
MT07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
Former [2016/33]HU06.12.2010
BG07.05.2014
CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MT07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
Former [2016/32]HU06.12.2010
BG07.05.2014
CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
Former [2016/28]BG07.05.2014
CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
Former [2016/27]CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
Former [2016/22]CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
GR08.08.2014
Former [2015/36]CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SI07.05.2014
SK07.05.2014
GR08.08.2014
Former [2015/11]CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
RO07.05.2014
RS07.05.2014
SK07.05.2014
GR08.08.2014
Former [2015/10]CY07.05.2014
EE07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
RS07.05.2014
SK07.05.2014
GR08.08.2014
Former [2014/52]CY07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
RS07.05.2014
GR08.08.2014
Former [2014/50]CY07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
GR08.08.2014
Former [2014/48]CY07.05.2014
LT07.05.2014
Former [2014/47]CY07.05.2014
Documents cited:Search[A]US2003138390  (SAINT-LEGER DIDIER [FR]) [A] 1-16 * the whole document * * paragraph [0018] - paragraph [0019] * * paragraph [0023] * * claims 6,13,17 *
 [A]  - Dial Sm ET AL, "Efficacy of 4-methylpyrazole for treatment of ethylene glycol intoxication in dogs.", (19940101), URL: http://www.ncbi.nlm.nih.gov/pubmed/7887524, (20121212), XP055047588 [A] 1-16 * abstract *
International search[Y]US2008021083  (DALEY THOMAS E [US]);
 [Y]US2005069587  (MODI NISHIT BACHULAL [US], et al);
 [Y]US2005147565  (SEQUEIRA JOEL A [US], et al);
 [Y]US6120806  (WHITMIRE DAVID R [US]);
 [A]  - FEIERMAN ET AL., "°Increased Sensitivity of the Microsomal Oxidation of Ethanol to Inhibition by Pyrazole and 4-Methylpyrazole After Chronic Ethanol Treatment.°", BIOCHEMICAL PHARMACOLOGY, (198710), vol. 36, no. 19, pages 3277 - 3283, XP008153898

DOI:   http://dx.doi.org/10.1016/0006-2952(87)90645-9
 [A]  - LINDROS ET AL., "A Simple Procedure Using 4-Methylpyrazole for Developing Tolerance and Other Chronic Alcohol Effects.°", ALCOHOL, (198404), vol. 1, no. ISS. 2, pages 145 - 150, XP024399797

DOI:   http://dx.doi.org/10.1016/0741-8329(84)90071-5
by applicant   - GOEDDE ET AL., HUM. GENET., (1992), vol. 88, pages 344 - 346
    - XIAO ET AL., J CLIN. INVEST., (1995), vol. 96, pages 2180 - 2186
    - WARD ET AL., ALCOHOL AND ALCOHOLISM, (1994), vol. 29, pages 433 - 438
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.