EP2345653 - Morphinan compounds [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 01.11.2013 Database last updated on 12.07.2024 | Most recent event Tooltip | 20.02.2015 | Lapse of the patent in a contracting state New state(s): MT | published on 25.03.2015 [2015/13] | Applicant(s) | For all designated states Concert Pharmaceuticals Inc. 99 Hayden Avenue, Suite 100 Lexington, MA 02421 / US | [2011/29] | Inventor(s) | 01 /
Tung, Roger 99 Hayden Avenue, 500 Lexington Massachusetts 02421 / US | [2011/38] |
Former [2011/29] | 01 /
Tung, Roger 99 Hayden Avenue 100 Lexington Massachusetts 02421 / US | Representative(s) | Robertson, James Alexander Marks & Clerk LLP 90 Long Acre London WC2E 9RA / GB | [N/P] |
Former [2012/52] | Robertson, James Alexander Marks & Clerk LLP 90 Long Acre London WC2E 9RA / GB | ||
Former [2011/29] | Robertson, James Alexander Marks & Clerk LLP 90 Long Acre London WC2E 9RA / GB | Application number, filing date | 11000763.0 | 30.04.2008 | [2011/29] | Priority number, date | US20070915130P | 01.05.2007 Original published format: US 915130 P | US20070916662P | 08.05.2007 Original published format: US 916662 P | US20070976044P | 28.09.2007 Original published format: US 976044 P | [2011/29] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2345653 | Date: | 20.07.2011 | Language: | EN | [2011/29] | Type: | B1 Patent specification | No.: | EP2345653 | Date: | 26.12.2012 | Language: | EN | [2012/52] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 24.05.2011 | Classification | IPC: | C07D471/08, C07B59/00, A61K31/439, A61P11/14 | [2011/29] | CPC: |
A61K31/195 (EP,US);
A61K31/4709 (EP,US);
A61K31/485 (EP,US);
A61K31/49 (EP,US);
A61P11/04 (EP);
A61P11/14 (EP);
A61P15/00 (EP);
A61P15/10 (EP);
A61P17/00 (EP);
A61P25/00 (EP);
A61P25/04 (EP);
A61P25/08 (EP);
A61P25/14 (EP);
A61P25/18 (EP);
A61P25/20 (EP);
A61P25/28 (EP);
A61P25/30 (EP);
A61P27/02 (EP);
A61P27/06 (EP);
A61P27/16 (EP);
A61P29/00 (EP);
A61P3/00 (EP);
A61P3/02 (EP);
A61P3/10 (EP);
A61P39/02 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07B59/002 (EP,US);
C07D221/28 (EP,US);
C07D471/08 (EP,US)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2011/29] | Title | German: | Morphinan Verbindungen | [2011/29] | English: | Morphinan compounds | [2011/29] | French: | Composés de morphine | [2011/29] | Examination procedure | 24.08.2011 | Examination requested [2011/41] | 25.08.2011 | Amendment by applicant (claims and/or description) | 29.06.2012 | Communication of intention to grant the patent | 08.11.2012 | Fee for grant paid | 08.11.2012 | Fee for publishing/printing paid | Parent application(s) Tooltip | EP08747238.7 / EP2152709 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20080747238) is 06.07.2010 | Opposition(s) | 27.09.2013 | No opposition filed within time limit [2013/49] | Fees paid | Renewal fee | 10.02.2011 | Renewal fee patent year 03 | 25.04.2011 | Renewal fee patent year 04 | 25.04.2012 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CY | 26.12.2012 | EE | 26.12.2012 | LV | 26.12.2012 | MC | 26.12.2012 | MT | 26.12.2012 | SI | 26.12.2012 | BG | 26.03.2013 | IS | 26.04.2013 | [2015/13] |
Former [2014/01] | CY | 26.12.2012 | |
EE | 26.12.2012 | ||
LV | 26.12.2012 | ||
MC | 26.12.2012 | ||
SI | 26.12.2012 | ||
BG | 26.03.2013 | ||
IS | 26.04.2013 | ||
Former [2013/52] | CY | 26.12.2012 | |
EE | 26.12.2012 | ||
LV | 26.12.2012 | ||
SI | 26.12.2012 | ||
BG | 26.03.2013 | ||
IS | 26.04.2013 | ||
Former [2013/35] | EE | 26.12.2012 | |
LV | 26.12.2012 | ||
SI | 26.12.2012 | ||
BG | 26.03.2013 | ||
IS | 26.04.2013 | ||
Former [2013/34] | LV | 26.12.2012 | |
SI | 26.12.2012 | ||
BG | 26.03.2013 | ||
IS | 26.04.2013 | ||
Former [2013/26] | LV | 26.12.2012 | |
SI | 26.12.2012 | ||
Former [2013/23] | LV | 26.12.2012 | Documents cited: | Search | [A] - G. HEINKELE ET. AL., "Synthesis of [2H3]-dextromethorphan and its major urinary metabolites [2H3]-dextrorphan and [2H3]-dextrorphan-beta-glucoronide", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, (2002), vol. 45, pages 1153 - 1158, XP002490642 [A] 1-21 * whole article * DOI: http://dx.doi.org/10.1002/jlcr.640 | [A] - T.H. EICHHOLD ET. AL., "Highly sensitive high-peformance liquid chromatographic-tandem mass spectrometric method for the analysis of dextromorphan in human plasma.", JOURNAL OF CHROMATOGRAPHY B, (1997), vol. 698, pages 147 - 154, XP002490644 [A] 1-21 * figure 1 * DOI: http://dx.doi.org/10.1016/S0378-4347(97)00308-3 | [A] - G. HEINKELE ET. AL., "Synthesis of [2H]-labelled phase I metabolites using 1-[2H]-pyridinium hydrochloride.", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, (2005), vol. 48, pages 457 - 461, XP002490645 [A] 1-21 * figure 1 * DOI: http://dx.doi.org/10.1002/jlcr.941 | [AP] - H. BÖLCSKEI ET. AL., "Synthesis of deuterated dextromethorphan derivatives.", ARKIVOK, (20080301), vol. 2008, no. iii, pages 182 - 193, XP002490643 [AP] 1-21 * page 183 - page 184; figure 1 * | by applicant | US4316888 | US4446140 | US4694010 | US4898860 | US5166207 | US5304121 | US5336980 | US5350756 | US5366980 | US5863927 | US5886026 | US6099562 | US6197830 | US6207164 | US2001044446 | US2002103109 | USRE38115E | US6583152 | US2004087479 | US6803031 | US2005129783 | US2005203125 | US7014866 | US2006079502 | US2006094744 | US7114547 | US2007191411 | - MILLER, SC ET AL., ADDICT BIOL, (2005), vol. 10, no. 4, pages 325 - 7 | - NICHOLSON, KL ET AL., PSYCHOPHARMACOLOGY (BERL), (19990901), vol. 146, no. 1, pages 49 - 59 | - PENDER, ES ET AL., PEDIATR EMERG CARE, (1991), vol. 7, pages 163 - 7 | - ZAWERTAILO LA ET AL., J CLIN PSYCHOPHARMACOL, (199808), vol. 18, no. 4, pages 332 - 7 | - WADA E ET AL., SEIKAGAKU, (1994), vol. 66, page 15 | - GANES LZ ET AL., COMP BIOCHEM PHYSIOL A MOL INTEGR PHYSIOL, (1998), vol. 119, page 725 | - KIM HC ET AL., BIOORG MED CHEM LETT, (2001), vol. 11, page 1651 | - NEWMAN AH ET AL., J MED CHEM, (1992), vol. 35, page 4135 | - FREIREICH ET AL., CANCER CHEMOTHER. REP, (1966), vol. 50, page 219 | - Scientific Tables, Geigy Pharmaceuticals, ARDSLEY, (1970), page 537 | - SIEGEL BW; SREEKRISHNA K; BARON BM, "Binding of the radiolabeled glycine site antagonist [3H]MDS105,519 to homomeric NMDA-NRIa receptors", EUR J PHARMACOL., (1996), vol. 312, no. 3, pages 357 - 365 | - GOLDMAN ME; JACOBSON AE; RICE KC; PAUL SM, "Differentiation of [.H] phencyclidine and (+)-[.H]SKF-10047 binding sites in rat cerebral cortex", FEBS LETT., (1985), vol. 190, pages 333 - 336 | - GANAPATHY ME; PRASAD PD; HUANG W; SETH P; LEIBACH FH; GANAPATHY V, "Molecular and ligand-binding characterization of the s-receptor in the Jurkat human T lymphocyte cell line", J PHARMACOL EXP THER., (1999), vol. 289, pages 251 - 260 | US19620609166 | US20040609760 | US20070915130 |