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Extract from the Register of European Patents

EP About this file: EP2599767

EP2599767 - Phenylbutyl-derivatives [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  20.06.2014
Database last updated on 02.08.2024
Most recent event   Tooltip20.06.2014Application deemed to be withdrawnpublished on 23.07.2014  [2014/30]
Applicant(s)For all designated states
Lunamed AG
Rabengasse 4
7000 Chur / CH
[2013/23]
Inventor(s)01 / Truog, Peter
Rabengasse 4
7000 Chur / CH
02 / Buschmann, Helmut H.
Sperberweg 15
52076 Aachen (Walheim) / DE
 [2013/23]
Representative(s)Peters, Hajo, et al
ZACCO GmbH
Bayerstrasse 83
80335 München / DE
[N/P]
Former [2013/23]Peters, Hajo, et al
ZACCO GmbH Bayerstrasse 83
80335 München / DE
Application number, filing date11010059.121.12.2011
[2013/23]
Priority number, dateEP2011000947230.11.2011         Original published format: EP 11009472
[2013/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2599767
Date:05.06.2013
Language:EN
[2013/23]
Search report(s)(Supplementary) European search report - dispatched on:EP19.11.2012
ClassificationIPC:C07C69/14, C07C69/612, C07C69/86, C07C229/36, C07C233/51, A61K31/216
[2013/23]
CPC:
C07C229/36 (EP); C07C233/51 (EP); C07C69/157 (EP);
C07C69/612 (EP); C07C69/86 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/23]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:Phenylbutyl-Derivate[2013/23]
English:Phenylbutyl-derivatives[2013/23]
French:Dérivés de phénylbutyl[2013/23]
Examination procedure06.12.2013Application deemed to be withdrawn, date of legal effect  [2014/30]
13.01.2014Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2014/30]
Fees paidPenalty fee
Additional fee for renewal fee
31.12.201303   M06   Not yet paid
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO2010103976  (UNIV NAGOYA NAT UNIV CORP [JP], et al) [X] 1-7,10,13 * product of Scheme 3; page 16, paragraph 34 *;
 [A]WO2008120205  (UNIV RAMOT [IL], et al) [A] 1-15 * claims 1, 8, 15, 53 * * page 2, lines 13-19 * * page 36; compounds AN-451 *;
 [A]US5939455  (REPHAELI ADA [US]) [A] 1-15 * claims 1, 4, 5 * * column 1, lines 40-54 *;
 [X]  - WALSH JAMES P ET AL, "sn-1,2-Diacylglycerol kinase of Escherichia coli. Diacylglycerol analogs define specificity and mechanism", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (19900315), vol. 265, no. 8, ISSN 0021-9258, pages 4374 - 4381, XP002677411 [X] 1-8,10,14 * page 4375; table I; compound XXIV *
 [X]  - SAITO M ET AL, "SYNTHESIS AND INHIBITORY ACTIVITY OF ACYL-PEPTIDYL-PYRROLIDINE DERIVATIVES TOWARD POST-PROLINE CLEAVING ENZYME; A STUDY OF SUBSITE SPECIFICITY", JOURNAL OF ENZYME INHIBITION, NEW YORK, NY, US, (19910101), vol. 5, no. 1, pages 51 - 75, XP000197459 [X] 1-6,10,14 * page 54, lines 3-4; compounds 4-PhBuAlaOH *
 [X]  - LEVY B ET AL, "Phenylpropionyl-dl-alanine and Phenylbutyryldl-alanine", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL SOCIETY, LETCHWORTH; GB, (19480101), vol. 71, ISSN 0368-1769, page 1512, XP002592291 [X] 1-6,10 * page 1512, column 1 *
 [X]  - INES MANDL ET AL, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (19500419), vol. 72, no. 4, doi:10.1021/ja01160a106, ISSN 0002-7863, pages 1790 - 1792, XP055043111 [X] 1-6,10 * entry 6; page 1790, column 2; table I *

DOI:   http://dx.doi.org/10.1021/ja01160a106
 [I]  - MICHAL ENTIN-MEER ET AL, "AN-113, a novel prodrug of 4-phenylbutyrate with increased anti-neoplastic activity in glioma cell lines", CANCER LETTERS, (20070801), vol. 253, no. 2, doi:10.1016/j.canlet.2007.01.022, ISSN 0304-3835, pages 205 - 214, XP055043372 [I] 9,11,12,15 * page 206; table 1; compounds AN-113 * * page 206, column 1, lines 4-10 *

DOI:   http://dx.doi.org/10.1016/j.canlet.2007.01.022
 [A]  - HAROLD L. NEWMARK ET AL, "Butyrate and phenylacetate as differentiating agents: Practical problems and opportunities", JOURNAL OF CELLULAR BIOCHEMISTRY, (19950101), vol. 59, no. S22, doi:10.1002/jcb.240590831, ISSN 0730-2312, pages 247 - 253, XP055043377 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1002/jcb.240590831
by applicantWO9300786
 WO9510271
 EP0725635
 EP1427396
 WO03022253
    - "Oral Drug Delivery", TAKADA, K.; YOSHIKAWA, H., Encyclopedia of Controlled Drug Delivery, JOHN WILEY & SONS, INC., (1999), vol. 2, pages 728 - 742
    - "Oral drug delivery, small intestine and colon", FIX, J., Encyclopedia of Controlled Drug Delivery, JOHN WILEY & SONS, INC., (1999), vol. 2, pages 698 - 728
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.