EP2395018 - Human binding molecules having killing activity against staphylococci and uses thereof [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 02.12.2016 Database last updated on 09.07.2024 | Most recent event Tooltip | 20.07.2018 | Lapse of the patent in a contracting state New state(s): MT | published on 22.08.2018 [2018/34] | Applicant(s) | For all designated states Crucell Holland B.V. Archimedesweg 4 2333 CN Leiden / NL | [2016/04] |
Former [2011/50] | For all designated states Crucell Holland B.V. Archimedesweg 4 2333 CN Leiden / NL | Inventor(s) | 01 /
Throsby, Mark Archimedesweg 4-6 2333 CN Leiden / NL | 02 /
Geuijen, Cecilia A.W. Archimedesweg 4-6 2333 CN Leiden / NL | 03 /
De Kruif, Cornelis Adriaan Archimedesweg 4-6 2333 CN Leiden / NL | [2011/50] | Representative(s) | Beslier, Victor Janssen Vaccines & Prevention B.V. Archimedesweg 4-6 2333 CN Leiden / NL | [N/P] |
Former [2016/04] | Beslier, Victor Crucell Holland B.V. IP Department Archimedesweg 4-6 2333 CN Leiden / NL | ||
Former [2011/50] | Verhage, Richard Abraham Crucell Holland B.V. IP Department Archimedesweg 4-6 2333 CN Leiden / NL | Application number, filing date | 11170742.8 | 05.06.2007 | [2011/50] | Priority number, date | US20060811477P | 06.06.2006 Original published format: US 811477 P | EP20060124231 | 16.11.2006 Original published format: EP 06124231 | EP20070103584 | 06.03.2007 Original published format: EP 07103584 | [2011/50] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2395018 | Date: | 14.12.2011 | Language: | EN | [2011/50] | Type: | B1 Patent specification | No.: | EP2395018 | Date: | 27.01.2016 | Language: | EN | [2016/04] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 07.11.2011 | Classification | IPC: | C07K16/12, C12N15/13, A61K39/40, A61P31/04 | [2011/51] | CPC: |
C07K16/1271 (EP,US);
C07K16/12 (KR);
A61K39/40 (KR);
A61P31/00 (EP);
A61P31/04 (EP);
A61P43/00 (EP);
C12N15/11 (KR);
A61K2039/505 (EP,US);
C07K2317/21 (EP,US);
C07K2317/56 (EP,US);
C07K2317/565 (EP,US);
C07K2317/622 (EP,US);
C07K2317/77 (EP,US)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR [2011/50] | Title | German: | Menschliche bindende Moleküle mit Abtötungswirkung gegen Staphylokokken und ihre Verwendung | [2011/50] | English: | Human binding molecules having killing activity against staphylococci and uses thereof | [2011/50] | French: | Molécules de liaison humaines dotées d'une activité de destruction de staphylocoques et leurs utilisations | [2011/50] | Examination procedure | 21.06.2011 | Examination requested [2011/50] | 25.06.2012 | Amendment by applicant (claims and/or description) | 14.12.2012 | Despatch of a communication from the examining division (Time limit: M08) | 25.09.2013 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 26.11.2013 | Reply to a communication from the examining division | 20.05.2014 | Despatch of a communication from the examining division (Time limit: M04) | 25.09.2014 | Reply to a communication from the examining division | 16.10.2014 | Despatch of a communication from the examining division (Time limit: M04) | 24.02.2015 | Reply to a communication from the examining division | 28.07.2015 | Communication of intention to grant the patent | 24.11.2015 | Fee for grant paid | 24.11.2015 | Fee for publishing/printing paid | 24.11.2015 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP07765322.8 / EP2027155 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20070765322) is 11.08.2009 | Opposition(s) | 28.10.2016 | No opposition filed within time limit [2017/01] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 26.11.2013 | Request for further processing filed | 26.11.2013 | Full payment received (date of receipt of payment) Request granted | 06.12.2013 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 25.06.2012 | Request for further processing filed | 25.06.2012 | Full payment received (date of receipt of payment) Request granted | 18.07.2012 | Decision despatched | Fees paid | Renewal fee | 21.06.2011 | Renewal fee patent year 03 | 21.06.2011 | Renewal fee patent year 04 | 21.06.2011 | Renewal fee patent year 05 | 31.03.2012 | Renewal fee patent year 06 | 28.05.2013 | Renewal fee patent year 07 | 31.03.2014 | Renewal fee patent year 08 | 10.06.2015 | Renewal fee patent year 09 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 27.01.2016 | BE | 27.01.2016 | CY | 27.01.2016 | CZ | 27.01.2016 | EE | 27.01.2016 | ES | 27.01.2016 | IT | 27.01.2016 | PL | 27.01.2016 | RO | 27.01.2016 | SK | 27.01.2016 | TR | 27.01.2016 | BG | 27.04.2016 | GR | 28.04.2016 | PT | 27.05.2016 | MT | 30.06.2016 | [2018/33] |
Former [2018/29] | AT | 27.01.2016 | |
BE | 27.01.2016 | ||
CY | 27.01.2016 | ||
CZ | 27.01.2016 | ||
EE | 27.01.2016 | ||
ES | 27.01.2016 | ||
IT | 27.01.2016 | ||
PL | 27.01.2016 | ||
RO | 27.01.2016 | ||
SK | 27.01.2016 | ||
TR | 27.01.2016 | ||
BG | 27.04.2016 | ||
GR | 28.04.2016 | ||
PT | 27.05.2016 | ||
Former [2017/20] | AT | 27.01.2016 | |
BE | 27.01.2016 | ||
CZ | 27.01.2016 | ||
EE | 27.01.2016 | ||
ES | 27.01.2016 | ||
IT | 27.01.2016 | ||
PL | 27.01.2016 | ||
RO | 27.01.2016 | ||
SK | 27.01.2016 | ||
BG | 27.04.2016 | ||
GR | 28.04.2016 | ||
PT | 27.05.2016 | ||
Former [2017/03] | AT | 27.01.2016 | |
BE | 27.01.2016 | ||
CZ | 27.01.2016 | ||
EE | 27.01.2016 | ||
ES | 27.01.2016 | ||
IT | 27.01.2016 | ||
PL | 27.01.2016 | ||
RO | 27.01.2016 | ||
SK | 27.01.2016 | ||
GR | 28.04.2016 | ||
PT | 27.05.2016 | ||
Former [2016/50] | AT | 27.01.2016 | |
CZ | 27.01.2016 | ||
EE | 27.01.2016 | ||
ES | 27.01.2016 | ||
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PL | 27.01.2016 | ||
RO | 27.01.2016 | ||
SK | 27.01.2016 | ||
GR | 28.04.2016 | ||
PT | 27.05.2016 | ||
Former [2016/49] | AT | 27.01.2016 | |
EE | 27.01.2016 | ||
ES | 27.01.2016 | ||
IT | 27.01.2016 | ||
PL | 27.01.2016 | ||
GR | 28.04.2016 | ||
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Former [2016/38] | AT | 27.01.2016 | |
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PL | 27.01.2016 | ||
GR | 28.04.2016 | ||
PT | 27.05.2016 | ||
Former [2016/36] | AT | 27.01.2016 | |
ES | 27.01.2016 | ||
IT | 27.01.2016 | ||
PL | 27.01.2016 | ||
GR | 28.04.2016 | ||
Former [2016/35] | ES | 27.01.2016 | |
GR | 28.04.2016 | Documents cited: | Search | [AD]WO03059260 (BIOSYNEXUS INC [US], et al) [AD] 1-11 * the whole document, especially example 8 *; | [AD]WO03059259 (BIOSYNEXUS INC [US], et al) [AD] 1-11* the whole document, especially example 12 *; | [I]WO2005103084 (BRIGHAM & WOMENS HOSPITAL [US], et al) [I] 1-11 * the whole document, especially figures 7 and 12 * | by applicant | WO8403564 | WO9309872 | US5696108 | WO9815833 | WO0063403 | US6265150 | WO02103012 | WO03059259 | WO03059260 | WO2004043405 | WO2005118644 | - BOEL E, VERLAAN S, POPPELIER MJ, WESTERDAAL NA, VAN STRIJP JA, LOGTENBERG T, "Functional human monoclonal antibodies of all isotypes constructed from phage display library-derived single-chain Fv antibody fragments", J. IMMUNOL. METHODS, (2000), vol. 239, doi:doi:10.1016/S0022-1759(00)00170-8, pages 153 - 166, XP004204325 DOI: http://dx.doi.org/10.1016/S0022-1759(00)00170-8 | - BURTON DR, BARBAS CF, "Human antibodies from combinatorial libraries", ADV. IMMUNOL., (1994), vol. 57, doi:doi:10.1016/S0065-2776(08)60674-4, pages 191 - 280, XP009164108 | - CANTINIEAUX B, HARIGA C, COURTOY P, HUPIN J, FONDU P, "Staphylococcus aureus phagocytosis. A new cytofluorometric method using FITC and paraformaldehyde", J IMMUNOL. METHODS, (1989), vol. 121, doi:doi:10.1016/0022-1759(89)90161-0, pages 203 - 208, XP023653987 DOI: http://dx.doi.org/10.1016/0022-1759(89)90161-0 | - CHOTHIA, LESK, "Canonical structures for the hypervariable regions of immunoglobulins", J. MOL. BIOL., (1987), vol. 196, doi:doi:10.1016/0022-2836(87)90412-8, pages 901 - 917, XP024010426 DOI: http://dx.doi.org/10.1016/0022-2836(87)90412-8 | - CHOU, TC, P TALALAY, "Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors", ADV. ENZYME REGUL., (1984), vol. 22, doi:doi:10.1016/0065-2571(84)90007-4, pages 27 - 55, XP023796270 DOI: http://dx.doi.org/10.1016/0065-2571(84)90007-4 | - DE KRUIF J, TERSTAPPEN L, BOEL E, LOGTENBERG T, "Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library", PROC. NATL. ACAD. SCI. USA, vol. 92, doi:doi:10.1073/pnas.92.9.3938, page 3938, XP002149535 DOI: http://dx.doi.org/10.1073/pnas.92.9.3938 | - DE KRUIF J, BOEL E, LOGTENBERG T, "Selection and application of human single-chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions", J. MOL. BIOL., vol. 248, pages 97 - 105 | - HULS G, HEIJNEN IJ, CUOMO E, VAN DER LINDEN J, BOEL E, VAN DE WINKEL J, LOGTENBERG T, "Antitumor immune effector mechanisms recruited by phage display- derived fully human IgG and IgAl monoclonal antibodies", CANCER RES., (1999), vol. 59, pages 5778 - 5784 | - SLOOTSTRA JW, PUIJK WC, LIGTVOET GJ, LANGEVELD JP, MELOEN RH, "Structural aspects of antibody-antigen interaction revealed through small random peptide libraries", MOL. DIVERS, (1996), vol. 1, pages 87 - 96 |