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Extract from the Register of European Patents

EP About this file: EP2465925

EP2465925 - Light-activated cation channel and uses thereof [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 09.10.2020 Database last updated on 19.10.2024
Former	Grant of patent is intended Status updated on 11.12.2019
Former	Examination is in progress Status updated on 21.12.2016
Most recent event Tooltip	09.10.2020	Application deemed to be withdrawn	published on 11.11.2020 [2020/46]
Applicant(s)	For all designated states The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel Building 170, Third Floor, Main Quad P.O. Box 20386 Stanford, CA 94305-2038 / US
	[2019/38]
Former [2015/25]	For all designated states The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel Building 170 3rd Floor, Main Quad P.O. Box 20386 Stanford CA 94305-2038 / US
Former [2015/24]	For all designated states The Board of Trustees of the Leland Stanford Junior University 3th Floor, Main Quad P.O. Box 20386 Stanford CA 94305-2038 / US
Former [2012/25]	For all designated states The Board Of Trustees Of The Leland Stanford Junior University Building 170 Third Floor Main Quad Stanford, CA 94305-2038 / US
Inventor(s)	01 / Boyden, Edward S 100 Memorial Dr. 11-2C Cambridge, MA Massachusetts / US
	02 / Deisseroth, Karl 70 Peter Coutts Circle Palo Alto, CA California 94305 / US
	[2012/25]
Representative(s)	Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB
	[N/P]
Former [2012/25]	Brasnett, Adrian Hugh, et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS / GB
Application number, filing date	11172106.4	24.07.2006
	[2012/25]
Priority number, date	US20050701799P	22.07.2005 Original published format: US 701799 P
	[2012/25]
Previously filed application, date	WO2006US28868	24.07.2006
	[2012/25]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP2465925
	Date:	20.06.2012
	Language:	EN
	[2012/25]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	22.05.2012
Classification	IPC:	C12N5/0793, C12N5/10, G01N33/68	[2019/42]
	CPC:	G01N33/6872 (EP,US); A61F2/18 (US); A61K31/137 (EP,US); A61K31/353 (EP,US); A61K31/405 (EP,US); A61K31/4172 (EP,US); (+) A61K35/30 (EP,US); A61L27/3604 (US); A61N5/0601 (US); A61N5/062 (US); A61N5/0622 (EP,US); A61P17/00 (EP); A61P21/00 (EP); A61P25/00 (EP); A61P25/02 (EP); A61P25/16 (EP); A61P25/24 (EP); A61P25/28 (EP); A61P25/30 (EP); A61P27/02 (EP); A61P29/00 (EP); A61P3/04 (EP); A61P31/12 (EP); A61P31/18 (EP); A61P31/20 (EP); A61P35/00 (EP); A61P43/00 (EP); A61P5/00 (EP); A61P5/02 (EP); A61P5/06 (EP); A61P5/48 (EP); A61P5/50 (EP); A61P7/00 (EP); A61P7/06 (EP); A61P9/00 (EP); C07K14/405 (US); C07K14/705 (EP,US); A01K2217/05 (EP,US); A01K2227/105 (EP,US); A01K2227/40 (EP,US); A01K2227/703 (EP,US); A01K2227/706 (EP,US); A61K38/00 (EP,US); A61K48/00 (EP,US); C07K2319/60 (EP,US); C12N2740/15043 (EP,US); C12N2740/15071 (EP,US); G01N2500/04 (EP,US); G01N2500/10 (US); Y02A90/10 (EP,US); Y10S530/82 (EP,US) (-)
	C-Set:	A61K35/30, A61K2300/00 (EP,US)
	Former IPC [2012/25]	C12N5/0793, C12N5/10
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2012/25]
Extension states	AL	Not yet paid
	BA	Not yet paid
	HR	Not yet paid
	MK	Not yet paid
	RS	Not yet paid
Title	German:	Lichtaktivierter Kationenkanal und dessen Verwendung	[2012/25]
	English:	Light-activated cation channel and uses thereof	[2012/25]
	French:	Canal à cations activés par la lumière et ses utilisations	[2012/25]
Examination procedure	30.06.2011	Examination requested [2012/25]
	19.12.2012	Amendment by applicant (claims and/or description)
	27.10.2014	Despatch of a communication from the examining division (Time limit: M06)
	22.07.2015	Reply to a communication from the examining division
	22.08.2016	Despatch of a communication from the examining division (Time limit: M06)
	22.02.2017	Reply to a communication from the examining division
	02.01.2018	Despatch of a communication from the examining division (Time limit: M06)
	03.10.2018	Reply to a communication from the examining division
	11.06.2019	Despatch of a communication from the examining division (Time limit: M02)
	16.08.2019	Reply to a communication from the examining division
	12.12.2019	Communication of intention to grant the patent
	03.06.2020	Application deemed to be withdrawn, date of legal effect [2020/46]
	26.06.2020	Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2020/46]
Parent application(s) Tooltip	EP06824781.6 / EP1919497
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060824781) is 25.06.2009
Request for further processing for:	The application is deemed to be withdrawn due to failure to reply to the examination report
	03.10.2018	Request for further processing filed
	03.10.2018	Full payment received (date of receipt of payment) Request granted
	15.10.2018	Decision despatched
	The application is deemed to be withdrawn due to failure to reply to the examination report
	22.07.2015	Request for further processing filed
	22.07.2015	Full payment received (date of receipt of payment) Request granted
	05.08.2015	Decision despatched
Fees paid	Renewal fee
	30.06.2011	Renewal fee patent year 03
	30.06.2011	Renewal fee patent year 04
	30.06.2011	Renewal fee patent year 05
	28.07.2011	Renewal fee patent year 06
	13.07.2012	Renewal fee patent year 07
	10.07.2013	Renewal fee patent year 08
	14.07.2014	Renewal fee patent year 09
	10.07.2015	Renewal fee patent year 10
	11.07.2016	Renewal fee patent year 11
	12.07.2017	Renewal fee patent year 12
	11.07.2018	Renewal fee patent year 13
	15.07.2019	Renewal fee patent year 14
	Penalty fee
	Additional fee for renewal fee
	31.07.2020	15 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[XA]US2003040080 (MIESENBOCK GERO [US], et al) [X] 1,6-9 * paragraph [0021] - paragraph [0022] * * paragraph [0115] * * paragraph [0123] - paragraph [0125] * [A] 2-4;
		[XI] - PAN Z-H ET AL, "Functional expression of a directly light-gated membrane channel in mammalian retinal neurons: A potential strategy for restoring light sensitivity to the retina after photoreceptor degeneration", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,, (20050501), XP009113473 [X] 1,4-12 * the whole document * [I] 2,3
		[XYI] - LIMA SUSANA Q ET AL, "Remote control of behavior through genetically targeted photostimulation of neurons", CELL, CELL PRESS, US, vol. 121, no. 1, doi:10.1016/J.CELL.2005.02.004, ISSN 0092-8674, (20050408), pages 141 - 152, (20050407), XP009159156 [X] 1,3,6-9 * page 141 * * page 146 * [Y] 4,5,10-12 [I] 2 DOI: http://dx.doi.org/10.1016/j.cell.2005.02.004
		[IY] - BANGHART MATTHEW ET AL, "Light-activated ion channels for remote control of neuronal firing", NATURE NEUROSCIENCE, NATURE AMERICA, INC, US, vol. 7, no. 12, doi:10.1038/NN1356, ISSN 1097-6256, (20041201), pages 1381 - 1386, (20041121), XP002523154 [I] 1-3 * page 1383 - page 1385 * [Y] 1,4-12 DOI: http://dx.doi.org/10.1038/NN1356
		[Y] - NAGEL G ET AL, "Channelrhodopsin-2, a directly light-gated cation-selective membrane channel", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, (20031125), vol. 100, no. 24, doi:10.1073/PNAS.1936192100, ISSN 0027-8424, pages 13940 - 13945, XP002406405 [Y] 1-12 * page 13941 - page 1395 * DOI: http://dx.doi.org/10.1073/pnas.1936192100
		[A] - ZEMELMAN B V ET AL, "Selective Photostimulation of Genetically ChARGed Neurons", NEURON, CELL PRESS, US, (20020103), vol. 33, doi:10.1016/S0896-6273(01)00574-8, ISSN 0896-6273, pages 15 - 22, XP003015919 [A] 1-12 * page 17 - page 20 * DOI: http://dx.doi.org/10.1016/S0896-6273(01)00574-8
		[A] - DAVIDSON B L ET AL, "VIRAL VECTORS FOR GENE DELIVERY TO THE NERVOUS SYSTEM", NATURE REVIEWS NEUROSCIENCE, NATURE PUBLISHING GROUP, LONDON, GB, (20030501), vol. 4, no. 5, doi:10.1038/NRN1104, ISSN 1471-0048, pages 353 - 364, XP001180914 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1038/nrn1104
		[XPY] - NAGEL ET AL, "Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses", CURRENT BIOLOGY, CURRENT SCIENCE, GB, (20051224), vol. 15, no. 24, doi:10.1016/J.CUB.2005.11.032, ISSN 0960-9822, pages 2279 - 2284, XP005230468 [XP] 1,4-12 * the whole document * [Y] 2,3 DOI: http://dx.doi.org/10.1016/j.cub.2005.11.032
		[XPAY] - LI XIANG ET AL, "Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, vol. 102, no. 49, doi:10.1073/PNAS.0509030102, ISSN 0027-8424, (20051206), pages 17816 - 17821, (20051123), XP009159155 [XP] 1,4,6-12 * page 17816 * * page 17819 - page 17820 * [A] 3,5 [Y] 2 DOI: http://dx.doi.org/10.1073/pnas.0509030102
		[XDPY] - BI ANDING ET AL, "Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration", NEURON, CELL PRESS, US, (20060406), vol. 50, no. 1, doi:10.1016/J.NEURON.2006.02.026, ISSN 0896-6273, pages 23 - 33, XP002406402 [XDP] 1,4-12 * page 23 - page 25 * [Y] 2,3 DOI: http://dx.doi.org/10.1016/j.neuron.2006.02.026
		[T] - FENG ZHANG ET AL, "Channelrhodopsin-2 and optical control of excitable cells", NATURE METHODS, NATURE PUBLISHING GROUP, GB, (20061001), vol. 3, no. 10, doi:10.1038/NMETH936, ISSN 1548-7091, pages 785 - 792, XP008144949 [T] * page 785 - page 791; table 1 * DOI: http://dx.doi.org/10.1038/nmeth936
		[T] - WANG H ET AL, "High-speed mapping of synaptic connectivity using photostimulation in Channel rhodopsin-2 transgenic mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, (20070508), vol. 104, no. 19, doi:10.1073/PNAS.0700384104, ISSN 0027-8424, pages 8143 - 8148, XP009159082 [T] * the whole document * DOI: http://dx.doi.org/10.1073/pnas.0700384104
		[T] - HAN XUE ET AL, "Millisecond-Timescale Optical Control of Neural Dynamics in the Nonhuman Primate Brain", NEURON, CELL PRESS, US, (20090401), vol. 62, no. 2, ISSN 0896-6273, pages 191 - 198, XP009159079 [T] * the whole document * DOI: http://dx.doi.org/10.1016/j.neuron.2009.03.011
	by applicant	- POUILLE ET AL., NATURE, (2004), vol. 429, page 717
		- NIRENBERG ET AL., NEURON, (1997), vol. 18, page 637
		- KLAUSBERGER ET AL., NATURE, (2003), vol. 421, page 844
		- HAUSSER ET AL., NEURON, (1997), vol. 19, page 665
		- KANDEL ET AL., J NEUROPHYSIOL, (1961), vol. 24, page 243
		- KANDEL ET AL., J NEUROPHYSIOL, (1961), vol. 24, page 225
		- DITTERICH ET AL., NAT NEUROSCI, (2003), vol. 6, page 891
		- GOLD ET AL., NATURE, (2000), vol. 404, page 390
		- SALZMAN ET AL., NATURE, (1990), vol. 346, page 174
		- MERMELSTEIN ET AL., J. NEUROSCI., (2000), vol. 20, page 266
		- BI ET AL., J. NEUROSCI., (1998), vol. 18, page 10464
		- SHEPHERD ET AL., NEURON, (2003), vol. 38, page 277
		- DENK ET AL., J NEUROSCI METHODS, (1994), vol. 54, page 151
		- PETTIT ET AL., J NEUROPHYSIOL, (1999), vol. 81, page 1424
		- YOSHIMURA ET AL., NATURE, (2005), vol. 433, page 868
		- DALVA ET AL., SCIENCE, (1994), vol. 265, page 255
		- KATZ ET AL., J NEUROSCI METHODS, (1994), vol. 54, page 205
		- LIMA ET AL., CELL, (2005), vol. 121, page 141
		- BANGHART ET AL., NAT NEUROSCI, (2004), vol. 7, page 1381
		- ZEMELMAN ET AL., PROC NATL ACAD SCI U S A, (2003), vol. 100, page 1352
		- FOSTER ET AL., NATURE, (2005), vol. 433, page 698
		- NAGEL, PROC. NATL. ACAD. SCI. USA, vol. 100, page 13940
		- YAN, GENOMICS, (2001), vol. 72, no. 2, page 193
		- DITTGEN, PNAS, (2004), vol. 101, pages 18206 - 18211
		- BI ET AL., NEURON, (2006), vol. 50, pages 23 - 33
		- EMERICH ET AL., NEUROSCI BIOBEHAV REV, vol. 16, pages 437 - 447
		- DATE ET AL., CELL TRANSPLANT, vol. 9, pages 705 - 709
		- AEBISCHER ET AL., EXP NEUROL., vol. 111, pages 269 - 275
		- TATARKIEWICZ ET AL., TRANSPLANTATION, vol. 67, no. 5, pages 665 - 671
		- YAMAZOE ET AL., BIOMATERIALS, (2006), vol. 27, pages 4871 - 4880
		- ORY ET AL., PROC NATL ACAD SCI U S A, (1996), vol. 93, page 11400
		- GORDON ET AL., CELL, (1987), vol. 50, page 445
		- FENG ET AL., NEURON, (2000), vol. 28, page 41

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