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Extract from the Register of European Patents

EP About this file: EP2604281

EP2604281 - Clicked somatostatin conjugated analogs for biological applications [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.06.2015
Database last updated on 02.09.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Centre National de la Recherche Scientifique (C.N.R.S.)
3 rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université de Bourgogne
Maison de l'Université
Esplanade Erasme
B.P. 27877
21078 Dijon Cedex / FR
For all designated states
Université de Cergy-Pontoise
33 Boulevard du Port
95011 Cergy-Pontoise Cedex / FR
[N/P]
Former [2014/31]For all designated states
Centre National de la Recherche Scientifique (CNRS)
3, rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université de Bourgogne
Maison de l'Université Esplanade Erasme B.P. 27877
21078 Dijon Cedex / FR
For all designated states
Université de Cergy-Pontoise
33 Boulevard du Port
95011 Cergy-Pontoise Cedex / FR
Former [2013/35]For all designated states
Centre National de la Recherche Scientifique (CNRS)
3, rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université de Bourgogne
Maison de l'Université Esplanade Erasme B.P. 27877
21078 Dijon Cedex / FR
For all designated states
Université de Cergy-Pontoise
33 Boulevard du Port
95011 Cergy-Pontoise Cedex / FR
Former [2013/34]For all designated states
Centre National de la Recherche Scientifique (CNRS)
3, rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université de Bourgogne Dijon
6 Boulevard Gabriel
21000 Dijon / FR
For all designated states
Université de Cergy-Pontoise
33 Boulevard du Port
95011 Cergy-Pontoise Cedex / FR
Former [2013/25]For all designated states
Centre National de la Recherche Scientifique (CNRS)
3, rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université de Bourgogne Dijon
6 Boulevard Gabriel
21000 Dijon / FR
Inventor(s)01 / D'Addona, Debora M
Rue Rimaggio, 211
50019 Sesto Fiorentino / IT
02 / Bernhard, Claire
44 rue Colson
21000 Dijon / FR
03 / Rovero, Anna Maria
rue Guidalessi, 2
50127 Florence / IT
04 / Denat, Franck
6 rue Jacquard
21000 Dijon / FR
05 / Chorev, Michael
205 South Street
Chestnut Hill, Massachusetts 02467 / US
 [2014/10]
Former [2013/25]01 / D'Addona, Debora M
Rue Rimaggio, 211
I-50019 Sesto Fiorentino / IT
02 / Bernhard, Claire
44 rue Colson
21000 Dijon / FR
03 / Rovero, Anna Maria
rue Guidalessi, 2
50127 Florence / IT
04 / Denat, Franck
6 rue Jacquard
21000 Dijon / FR
05 / Chorev, Michael
205 south street
Chestnut Hill, MA Massachusetts 02467 / US
Representative(s)Cabinet Armengaud Aîné
16, Rue Gaillon
75002 Paris / FR
[N/P]
Former [2013/25]Peaucelle, Chantal, et al
Cabinet Armengaud Aîné 3, Avenue Bugeaud
75116 Paris / FR
Application number, filing date11193530.014.12.2011
[2013/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2604281
Date:19.06.2013
Language:EN
[2013/25]
Type: B1 Patent specification 
No.:EP2604281
Date:30.07.2014
Language:EN
[2014/31]
Search report(s)(Supplementary) European search report - dispatched on:EP09.07.2012
ClassificationIPC:A61K47/48, C07K7/06, C07K7/56, A61K49/00, A61K51/08, A61K38/08
[2013/25]
CPC:
A61K49/0056 (EP,US); A61K51/083 (US); A61K47/547 (EP,US);
A61K47/64 (EP,US); A61K49/108 (EP,US); A61K49/14 (EP,US);
A61K51/0482 (US); A61K51/085 (EP,US); A61K51/088 (US);
C07K14/655 (EP,US); A61K38/00 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/25]
TitleGerman:Geklickte, somatostatinkonjugierte Analoga für biologische Anwendungen[2013/25]
English:Clicked somatostatin conjugated analogs for biological applications[2013/25]
French:Analogues conjugués de somatostatine coupés pour des applications biologiques[2013/25]
Examination procedure26.11.2013Amendment by applicant (claims and/or description)
26.11.2013Examination requested  [2014/01]
06.02.2014Communication of intention to grant the patent
05.06.2014Fee for grant paid
05.06.2014Fee for publishing/printing paid
05.06.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.02.2014
Opposition(s)04.05.2015No opposition filed within time limit [2015/28]
Fees paidRenewal fee
25.12.2013Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU14.12.2011
AL30.07.2014
AT30.07.2014
BE30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
MC30.07.2014
MK30.07.2014
MT30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
SM30.07.2014
TR30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
[2018/46]
Former [2018/31]HU14.12.2011
AT30.07.2014
BE30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
MC30.07.2014
MK30.07.2014
MT30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
SM30.07.2014
TR30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
Former [2016/33]HU14.12.2011
AT30.07.2014
BE30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
MC30.07.2014
MT30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
SM30.07.2014
TR30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
Former [2016/32]HU14.12.2011
AT30.07.2014
BE30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
MC30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
SM30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
Former [2016/27]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
MC30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
SM30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
BE31.12.2014
Former [2016/22]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
SM30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
BE31.12.2014
Former [2015/51]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SI30.07.2014
SK30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
BE31.12.2014
Former [2015/46]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SK30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
IE14.12.2014
LU14.12.2014
BE31.12.2014
Former [2015/35]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SK30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
LU14.12.2014
BE31.12.2014
Former [2015/30]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SK30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
BE31.12.2014
Former [2015/23]AT30.07.2014
CY30.07.2014
CZ30.07.2014
DK30.07.2014
EE30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
SK30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
Former [2015/22]AT30.07.2014
CY30.07.2014
DK30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RO30.07.2014
RS30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
Former [2015/12]AT30.07.2014
CY30.07.2014
ES30.07.2014
FI30.07.2014
HR30.07.2014
LT30.07.2014
LV30.07.2014
PL30.07.2014
RS30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
IS30.11.2014
PT02.12.2014
Former [2015/11]CY30.07.2014
ES30.07.2014
FI30.07.2014
LT30.07.2014
PL30.07.2014
BG30.10.2014
NO30.10.2014
GR31.10.2014
PT02.12.2014
Former [2015/10]ES30.07.2014
FI30.07.2014
LT30.07.2014
BG30.10.2014
NO30.10.2014
Former [2015/09]FI30.07.2014
LT30.07.2014
Former [2015/08]LT30.07.2014
Documents cited:Search[A]WO9965508  (PEPTOR LTD [IL], et al) [A] 1-19 * the whole document *;
 [A]EP1598366  (GIUNTINI MAURO [IT], et al) [A] 1-19 * the whole document *;
 [A]WO2010004512  (ADVANCED ACCELERATOR APPLIC S [FR], et al) [A] 1-19 * the whole document *;
 [A]  - D'ADDONA DEBORA ET AL, "Novel sst(5)-selective somatostatin dicarba-analogues: synthesis and conformation- affinity relationships", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 51, no. 3, doi:10.1021/JM070886I, ISSN 0022-2623, (20080214), pages 512 - 520, (20080123), XP008104582 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1021/JM070886I
 [A]  - FLAVIA BARRAGÁN ET AL, "Solid-phase synthesis and DNA binding studies of dichloroplatinum(ii) conjugates of dicarba analogues of octreotide as new anticancer drugs", CHEMICAL COMMUNICATIONS, (20090101), no. 31, doi:10.1039/b909698a, ISSN 1359-7345, page 4705, XP055029959 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1039/b909698a
 [A]  - ALESSANDRA DI CIANNI ET AL, "Novel Octreotide Dicarba-analogues with High Affinity and Different Selectivity for Somatostatin Receptors", JOURNAL OF MEDICINAL CHEMISTRY, (20100826), vol. 53, no. 16, doi:10.1021/jm1005868, ISSN 0022-2623, pages 6188 - 6197, XP055029962 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm1005868
 [A]  - FLAVIA BARRAGÁN ET AL, "Photocontrolled DNA Binding of a Receptor-Targeted Organometallic Ruthenium(II) Complex", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (20110907), vol. 133, no. 35, doi:10.1021/ja205235m, ISSN 0002-7863, pages 14098 - 14108, XP055029963 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1021/ja205235m
 [A]  - MASUDA RYO ET AL, "Concise site-specific synthesis of DTPA-peptide conjugates: application to imaging probes for the chemokine receptor CXCR4.", BIOORGANIC & MEDICINAL CHEMISTRY 15 MAY 2011 LNKD- PUBMED:21524584, (20110515), vol. 19, no. 10, ISSN 1464-3391, pages 3216 - 3220, XP002677766 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1016/J.BMC.2011.03.059
 [A]  - RÖSCH FRANK ET AL, "Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS.", DALTON TRANSACTIONS (CAMBRIDGE, ENGLAND : 2003) 21 JUN 2011 LNKD- PUBMED:21445433, (20110621), vol. 40, no. 23, ISSN 1477-9234, pages 6104 - 6111, XP002677767 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1039/C0DT01504K
 [A]  - RIJKERS DIRK T S ET AL, "'Sulfo-click' for ligation as well as for site-specific conjugation with peptides, fluorophores, and metal chelators.", JOURNAL OF PEPTIDE SCIENCE : AN OFFICIAL PUBLICATION OF THE EUROPEAN PEPTIDE SOCIETY JAN 2010 LNKD- PUBMED:19924730, (201001), vol. 16, no. 1, ISSN 1099-1387, pages 1 - 5, XP002677768 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1002/PSC.1197
 [A]  - YIM CHENG-BIN ET AL, "Synthesis of DOTA-conjugated multimeric [Tyr3]octreotide peptides via a combination of Cu(I)-catalyzed "click" cycloaddition and thio acid/sulfonyl azide "sulfo-click" amidation and their in vivo evaluation.", JOURNAL OF MEDICINAL CHEMISTRY 27 MAY 2010 LNKD- PUBMED:20411957, (20100527), vol. 53, no. 10, ISSN 1520-4804, pages 3944 - 3953, XP002677769 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1021/JM100246M
by applicantWO9804583
 WO2010004512
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.