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Extract from the Register of European Patents

EP About this file: EP2558490

EP2558490 - METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF CANCER RESISTANT TO ANAPLASTIC LYMPHOMA KINASE (ALK) KINASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.10.2017
Database last updated on 03.09.2024
FormerThe patent has been granted
Status updated on  11.11.2016
FormerGrant of patent is intended
Status updated on  02.11.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-2794 / US
[2013/08]
Inventor(s)01 / MORRIS, Stephan, W.
2532 Windy Oaks Drive
Germantown TN 38139 / US
02 / JIANG, Qin
6748 Bent Tree Avenue
Memphis TN 38134 / US
03 / CUI, Xiaoli
5304 Bears Paw Circle
Memphis TN 38120 / US
04 / XUE, Liquan
8302 Garden Willow Lane
Cordova TN 38016 / US
 [2013/08]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2013/08]Wright, Simon Mark
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date11721840.413.04.2011
[2016/50]
WO2011US32204
Priority number, dateUS2010076105015.04.2010         Original published format: US 761050
[2013/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011130340
Date:20.10.2011
Language:EN
[2011/42]
Type: A1 Application with search report 
No.:EP2558490
Date:20.02.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 20.10.2011 takes the place of the publication of the European patent application.
[2013/08]
Type: B1 Patent specification 
No.:EP2558490
Date:14.12.2016
Language:EN
[2016/50]
Search report(s)International search report - published on:EP20.10.2011
ClassificationIPC:C07K14/71, G01N33/53, A01K67/027, C07K16/30, C12N1/15, C12N1/21, C12N5/10, C12Q1/48, C12Q1/68, G01N33/574
[2016/22]
CPC:
C12Q1/6886 (EP,KR,US); C12N9/12 (KR,US); A61P35/00 (EP);
A61P43/00 (EP); C07K14/71 (EP,KR,US); C12Q1/485 (EP,KR,US);
G01N33/5308 (KR); G01N33/574 (EP,KR,US); C12Q2600/156 (EP,US) (-)
Former IPC [2013/08]C07K14/71, G01N33/53, A01K67/027, C07K16/30, C12N1/15, C12N1/21, C12N5/10
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/08]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN FÜR DIE DIAGNOSE UND BEHANDLUNG VON GEGENÜBER ALK-KINASEHEMMERN RESISTENTEM KREBS[2013/08]
English:METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF CANCER RESISTANT TO ANAPLASTIC LYMPHOMA KINASE (ALK) KINASE INHIBITORS[2013/08]
French:PROCÉDÉS ET COMPOSITIONS DESTINÉS AU DIAGNOSTIC ET AU TRAITEMENT D'UN CANCER RÉSISTANT AUX INHIBITEURS DE LA KINASE DU LYMPHOME ANAPLASIQUE (ALK)[2013/08]
Entry into regional phase01.11.2012National basic fee paid 
01.11.2012Designation fee(s) paid 
01.11.2012Examination fee paid 
Examination procedure01.11.2012Examination requested  [2013/08]
03.06.2013Amendment by applicant (claims and/or description)
11.11.2013Despatch of a communication from the examining division (Time limit: M06)
17.06.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
27.08.2014Reply to a communication from the examining division
27.11.2014Despatch of a communication from the examining division (Time limit: M06)
26.05.2015Reply to a communication from the examining division
10.09.2015Despatch of a communication from the examining division (Time limit: M04)
20.01.2016Reply to a communication from the examining division
06.06.2016Communication of intention to grant the patent
17.10.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
17.10.2016Fee for grant paid
17.10.2016Fee for publishing/printing paid
02.11.2016Information about intention to grant a patent
02.11.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.11.2013
Opposition(s)15.09.2017No opposition filed within time limit [2017/47]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
27.08.2014Request for further processing filed
27.08.2014Full payment received (date of receipt of payment)
Request granted
08.09.2014Decision despatched
Fees paidRenewal fee
08.04.2013Renewal fee patent year 03
28.04.2014Renewal fee patent year 04
27.04.2015Renewal fee patent year 05
27.04.2016Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU13.04.2011
AL14.12.2016
AT14.12.2016
BE14.12.2016
CY14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
MK14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
TR14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
MT13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
[2020/33]
Former [2020/15]HU13.04.2011
AT14.12.2016
BE14.12.2016
CY14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
MK14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
TR14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
MT13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2019/51]HU13.04.2011
AT14.12.2016
BE14.12.2016
CY14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
MK14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
MT13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2019/46]HU13.04.2011
AT14.12.2016
BE14.12.2016
CY14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
MT13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2019/31]HU13.04.2011
AT14.12.2016
BE14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
MT13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2018/43]AT14.12.2016
BE14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
MT13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2018/23]AT14.12.2016
BE14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IE13.04.2017
LU13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2018/13]AT14.12.2016
BE14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SI14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
LU13.04.2017
IS14.04.2017
PT14.04.2017
CH30.04.2017
LI30.04.2017
Former [2018/06]AT14.12.2016
BE14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
MC14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IS14.04.2017
PT14.04.2017
Former [2018/01]AT14.12.2016
BE14.12.2016
CZ14.12.2016
DK14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IS14.04.2017
PT14.04.2017
Former [2017/41]AT14.12.2016
BE14.12.2016
CZ14.12.2016
EE14.12.2016
ES14.12.2016
FI14.12.2016
HR14.12.2016
IT14.12.2016
LT14.12.2016
LV14.12.2016
NL14.12.2016
PL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
SK14.12.2016
SM14.12.2016
BG14.03.2017
NO14.03.2017
GR15.03.2017
IS14.04.2017
PT14.04.2017
Former [2017/35]CZ14.12.2016
EE14.12.2016
FI14.12.2016
HR14.12.2016
LT14.12.2016
LV14.12.2016
NL14.12.2016
RO14.12.2016
RS14.12.2016
SE14.12.2016
NO14.03.2017
GR15.03.2017
Former [2017/31]FI14.12.2016
HR14.12.2016
LT14.12.2016
LV14.12.2016
NL14.12.2016
RS14.12.2016
SE14.12.2016
NO14.03.2017
GR15.03.2017
Former [2017/28]FI14.12.2016
HR14.12.2016
LT14.12.2016
LV14.12.2016
RS14.12.2016
SE14.12.2016
NO14.03.2017
GR15.03.2017
Former [2017/12]LV14.12.2016
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DOI:   http://dx.doi.org/10.1038/nature07398
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DOI:   http://dx.doi.org/10.1038/nature07399
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 [XPI]  - T. SASAKI ET AL, "The Neuroblastoma-Associated F1174L ALK Mutation Causes Resistance to an ALK Kinase Inhibitor in ALK-Translocated Cancers", CANCER RESEARCH, (20101215), vol. 70, no. 24, doi:10.1158/0008-5472.CAN-10-2956, ISSN 0008-5472, pages 10038 - 10043, XP055004136 [XP] 1-23 * the whole document * [I] 24-38,53-65

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DOI:   http://dx.doi.org/10.1056/NEJMoa1007478
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