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Extract from the Register of European Patents

EP About this file: EP2585445

EP2585445 - POLYMORPHS OF AN ACTIVE PHARMACEUTICAL INGREDIENT [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  20.04.2023
Database last updated on 03.04.2025
Most recent event   Tooltip21.04.2023Revocation of patentpublished on 24.05.2023  [2023/21]
Applicant(s)For all designated states
Sandoz AG
Lichtstrasse 35
4056 Basel / CH
[2013/18]
Inventor(s)01 / HOTTER, Andreas
c/o Sandoz GmbH
Biochemiestrasse 10
A-6250 Kundl / AT
02 / GRIESSER, Ulrich
c/o University of Innsbruck Institut für Pharmazie
Innrain 52a
A-6020 Innsbruck / AT
03 / ADAMER, Verena
c/o University of Innsbruck Institut für Pharmazie
Innrain 52a
A-6020 Innsbruck / AT
04 / LANGES, Christoph
c/o University of Innsbruck Institut für Pharmazie
Innrain 52a
A-6020 Innsbruck / AT
 [2013/18]
Representative(s)Prüfer & Partner mbB Patentanwälte · Rechtsanwälte
Sohnckestraße 12
81479 München / DE
[N/P]
Former [2015/34]Prüfer & Partner GbR European Patent Attorneys
Sohnckestraße 12
81479 München / DE
Former [2013/18]Prüfer & Partner GbR European Patent Attorneys
Sohnckestrasse 12
81479 München / DE
Application number, filing date11727454.824.06.2011
[2015/34]
WO2011EP60630
Priority number, dateEP2010016734425.06.2010         Original published format: EP 10167344
[2013/18]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2011161245
Date:29.12.2011
Language:EN
[2011/52]
Type: A2 Application without search report 
No.:EP2585445
Date:01.05.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 29.12.2011 takes the place of the publication of the European patent application.
[2013/18]
Type: B1 Patent specification 
No.:EP2585445
Date:19.08.2015
Language:EN
[2015/34]
Search report(s)International search report - published on:EP08.03.2012
ClassificationIPC:C07D277/56, A61K31/425, A61P19/06
[2013/18]
CPC:
C07D277/56 (EP,US); A61P19/06 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/18]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:POLYMORPHE EINES PHARMAZEUTISCHEN WIRKSTOFFES[2013/18]
English:POLYMORPHS OF AN ACTIVE PHARMACEUTICAL INGREDIENT[2013/18]
French:POLYMORPHES D'UNE SUBSTANCE PHARMACEUTIQUE ACTIVE[2013/18]
Entry into regional phase13.12.2012National basic fee paid 
13.12.2012Designation fee(s) paid 
13.12.2012Examination fee paid 
Examination procedure13.12.2012Amendment by applicant (claims and/or description)
13.12.2012Examination requested  [2013/18]
13.11.2013Despatch of a communication from the examining division (Time limit: M04)
21.03.2014Reply to a communication from the examining division
12.08.2014Despatch of a communication from the examining division (Time limit: M04)
22.12.2014Reply to a communication from the examining division
09.03.2015Communication of intention to grant the patent
11.05.2015Observations by third parties
08.07.2015Fee for grant paid
08.07.2015Fee for publishing/printing paid
08.07.2015Receipt of the translation of the claim(s)
Divisional application(s)EP15181097.5  / EP2977372
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  13.11.2013
Opposition(s)Opponent(s)01  18.05.2016  24.05.2016  ADMISSIBLE
Alfred E. Tiefenbacher (GmbH & Co. KG)
Van-der-Smissen-Straße 1
22767 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 02  18.05.2016  24.05.2016  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Eder, Michael
Df-mp Dörries Frank-Molnia & Pohlman
Patentanwälte Rechtsanwälte PartG mbB
Fünf Höfe
Theatinerstrasse 16
80333 München / DE
 [2021/47]
Former [2021/20]
Opponent(s)01  18.05.2016  24.05.2016  ADMISSIBLE
Alfred E. Tiefenbacher (GmbH & Co. KG)
Van-der-Smissen-Straße 1
22767 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 02  18.05.2016  24.05.2016  ADMISSIBLE
Teva Pharmaceutical Industries Ltd
5 Basel Street
P.O. Box 3190
49131 Petah Tiqva / IL
Opponent's representative
Eder, Michael
Df-mp Dörries Frank-Molnia & Pohlman
Patentanwälte Rechtsanwälte PartG mbB
Fünf Höfe
Theatinerstrasse 16
80333 München / DE
Former [2016/26]
Opponent(s)01  18.05.2016  24.05.2016  ADMISSIBLE
Alfred E. Tiefenbacher (GmbH & Co. KG)
Van-der-Smissen-Straße 1
22767 Hamburg / DE
Opponent's representative
Hamm & Wittkopp Patentanwälte PartmbB, et al, et al
Jungfernstieg 38
20354 Hamburg / DE
 02  18.05.2016  24.05.2016  ADMISSIBLE
Teva Pharmaceutical Industries Ltd
5 Basel Street
P.O. Box 3190
49131 Petah Tiqva / IL
Opponent's representative
Eder, Michael
Df-mp Dörries Frank-Molnia & Pohlman
Patentanwälte Rechtsanwälte PartG mbB
Fünf Höfe
Theatinerstrasse 16
80333 München / DE
27.06.2016Invitation to proprietor to file observations on the notice of opposition
23.12.2016Reply of patent proprietor to notice(s) of opposition
31.01.2018Date of oral proceedings
18.04.2018Despatch of minutes of oral proceedings
30.01.2023Legal effect of revocation of patent [2023/21]
21.04.2023Despatch of communication that the patent will be revoked
Appeal following opposition25.05.2018Appeal received No.  T1079/18
28.08.2018Statement of grounds filed
30.01.2023Result of appeal procedure: revocation of the patent
21.04.2023Despatch of the decision of the Board of Appeal
15.05.2018Appeal received No.  T1079/18
28.08.2018Statement of grounds filed
30.01.2023Result of appeal procedure: revocation of the patent
21.04.2023Despatch of the decision of the Board of Appeal
25.04.2018Appeal received No.  T1079/18
06.08.2018Statement of grounds filed
30.01.2023Result of appeal procedure: revocation of the patent
21.04.2023Despatch of the decision of the Board of Appeal
30.01.2023Date of oral proceedings
Fees paidRenewal fee
10.06.2013Renewal fee patent year 03
31.03.2014Renewal fee patent year 04
10.06.2015Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU24.06.2011
AL19.08.2015
AT19.08.2015
BE19.08.2015
BG19.08.2015
CY19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
MK19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
SM19.08.2015
TR19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
IE24.06.2016
LU24.06.2016
CH30.06.2016
LI30.06.2016
MT30.06.2016
[2018/47]
Former [2018/38]HU24.06.2011
AT19.08.2015
BE19.08.2015
BG19.08.2015
CY19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
MK19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
SM19.08.2015
TR19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
IE24.06.2016
LU24.06.2016
CH30.06.2016
LI30.06.2016
MT30.06.2016
Former [2018/31]HU24.06.2011
AT19.08.2015
BE19.08.2015
CY19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
MK19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
SM19.08.2015
TR19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
IE24.06.2016
LU24.06.2016
CH30.06.2016
LI30.06.2016
MT30.06.2016
Former [2018/29]HU24.06.2011
AT19.08.2015
BE19.08.2015
CY19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
MK19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
SM19.08.2015
TR19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
IE24.06.2016
LU24.06.2016
CH30.06.2016
LI30.06.2016
Former [2018/28]HU24.06.2011
AT19.08.2015
BE19.08.2015
CY19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
MK19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
SM19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
IE24.06.2016
CH30.06.2016
LI30.06.2016
Former [2017/25]AT19.08.2015
BE19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
IE24.06.2016
CH30.06.2016
LI30.06.2016
Former [2017/07]AT19.08.2015
BE19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
MC19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2017/03]AT19.08.2015
BE19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2016/36]AT19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SI19.08.2015
SK19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2016/23]AT19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
RO19.08.2015
RS19.08.2015
SE19.08.2015
SK19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2016/22]AT19.08.2015
CZ19.08.2015
EE19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
RS19.08.2015
SE19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2016/11]AT19.08.2015
FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
RS19.08.2015
SE19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2016/10]FI19.08.2015
HR19.08.2015
LT19.08.2015
LV19.08.2015
RS19.08.2015
SE19.08.2015
NO19.11.2015
GR20.11.2015
IS19.12.2015
PT21.12.2015
Former [2016/09]FI19.08.2015
LT19.08.2015
LV19.08.2015
NO19.11.2015
GR20.11.2015
Former [2016/08]LT19.08.2015
NO19.11.2015
Former [2016/07]LT19.08.2015
Cited inInternational search[XD]EP1020454  (TEIJIN LTD [JP]) [XD] 1-3 * Paragraphs [0011], [0015], [0019], [0036]; claims; figure 2. *;
 [XD]US2005043375  (IWAI MICHIO [JP], et al) [XD] 1-7,15 * Claims 3, 15; paragraphs [0003], [0023-24], [0032], [0051], [0055-57]. *;
 [A]CN101648926  (CSPC OUYI PHARMACEUTICAL CO LT) [A] 1-7,15 * Pages 5-7 and 12, XRPD data. *;
 [L]  - Bernstein, Polymorphism in Molecular Crystals, Oxford, Clarendon Press, (2002), ISBN 0198506058, XP002608621 [L] 1-7,15 * The whole document. Cited as common general knowledge. *
ExaminationCN101817801
    - Ivanisevic et al., "Uses of X-Ray Powder Diffraction In the Pharmaceutical Industry", Ivanisevic et al., Gad (ed.), Pharmaceutical Sciences Encyclopedia: Drug Discovery, Development, and Manufacturing, John Wiley & Sons, Inc., pages 1 - 42
    - US Pharmacopeia (USP 29), no. 941, chapter "X-Ray Diffraction", 4 pages.
    - CAIRA, "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS", TOPICS IN CURRENT CHEMISTRY, (19980101), vol. 198, doi:10.1007/3-540-69178-2_5, ISSN 0340-1022, ISBN 978-3-540-36760-4, pages 163 - 208, XP001156954

DOI:   http://dx.doi.org/10.1007/3-540-69178-2_5
by applicantEP1020454
 US7361676
 US2005043375
otherWO2010144685
OppositionEP1020454
 US2005043375
 CN101648926
 CN101817801
    - BERNSTEIN, Polymorphism in Molecular Crystals, Oxford, CLARENDON PRESS, (20020000), pages 125 - 131, ISBN 0198506058, XP002608621
    - IVANISEVIC et al., "Uses of X-Ray Powder Diffraction In the Pharmaceutical Industry", Pharmaceutical Sciences Encyclopedia: Drug Discovery, Develop- ment, and Manufacturing, (20100000), pages 1 - 42, XP055007590

DOI:   http://dx.doi.org/10.1002/9780470571224.pse414
    - Anonymous, "X-Ray Diffraction", US Pharmacopeia, vol. 29, no. 941, (20050000), pages 1 - 4, URL: http://www.pharmacopeia.cn/v29240/usp29nf24s0_c941.html, XP055290539
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.