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Extract from the Register of European Patents

EP About this file: EP2591109

EP2591109 - BACTERIAL SURFACE DISPLAY AND SCREENING OF THIOETHER-BRIDGE-CONTAINING PEPTIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  03.03.2017
Database last updated on 19.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
MorphoSys AG
Semmelweisstrasse 7
82152 Planegg / DE
[2017/13]
Former [2015/18]For all designated states
MorphoSys AG
Lena-Christ-Strasse 48
82152 Planegg-Martinsried / DE
Former [2013/20]For all designated states
LanthioPep B.V.
Postbus 719
9700 AS Groningen / NL
Inventor(s)01 / BOSMA, Tjibbe
De Buorren 100
NL-8408 HP Lippenhuizen / NL
 [2013/20]
Representative(s)Hutter, Bernd
MorphoSys AG
Semmelweisstrasse 7
82152 Planegg / DE
[N/P]
Former [2016/17]Hutter, Bernd
MorphoSys AG
Lena-Christ-Straße 48
82152 Martinsried/Planegg / DE
Former [2013/20]Jansen, Cornelis Marinus, et al
VEREENIGDE Johan de Wittlaan 7
2517 JR Den Haag / NL
Application number, filing date11736181.606.07.2011
[2016/17]
WO2011NL50484
Priority number, dateEP2010016858906.07.2010         Original published format: EP 10168589
[2013/20]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012005578
Date:12.01.2012
Language:EN
[2012/02]
Type: A1 Application with search report 
No.:EP2591109
Date:15.05.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 12.01.2012 takes the place of the publication of the European patent application.
[2013/20]
Type: B1 Patent specification 
No.:EP2591109
Date:27.04.2016
Language:EN
[2016/17]
Search report(s)International search report - published on:EP12.01.2012
ClassificationIPC:C12N15/62, C12N15/10
[2013/20]
CPC:
C12N15/1037 (EP,US); G01N33/6803 (US); C12N15/625 (EP,US);
C07K2319/035 (EP,US); C07K2319/50 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/20]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:BAKTERIENOBERFLÄCHENDISPLAY UND SCREENING VON THIOETHER-BRÜCKEN-HALTIGEN PEPTIDEN[2013/20]
English:BACTERIAL SURFACE DISPLAY AND SCREENING OF THIOETHER-BRIDGE-CONTAINING PEPTIDES[2013/20]
French:PRÉSENTATION À LA SURFACE BACTÉRIENNE ET CRIBLAGE DE PEPTIDES CONTENANT DES PONTS THIOÉTHERS[2013/20]
Entry into regional phase10.01.2013National basic fee paid 
10.01.2013Designation fee(s) paid 
10.01.2013Examination fee paid 
Examination procedure10.01.2013Examination requested  [2013/20]
15.05.2013Amendment by applicant (claims and/or description)
16.04.2014Despatch of a communication from the examining division (Time limit: M06)
23.09.2014Reply to a communication from the examining division
17.02.2015Despatch of a communication from the examining division (Time limit: M04)
15.06.2015Reply to a communication from the examining division
12.11.2015Communication of intention to grant the patent
11.03.2016Fee for grant paid
11.03.2016Fee for publishing/printing paid
11.03.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.04.2014
Opposition(s)30.01.2017No opposition filed within time limit [2017/14]
Fees paidRenewal fee
15.07.2013Renewal fee patent year 03
30.06.2014Renewal fee patent year 04
23.07.2015Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU06.07.2011
AL27.04.2016
BG27.04.2016
CY27.04.2016
CZ27.04.2016
EE27.04.2016
HR27.04.2016
IS27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
MK27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SI27.04.2016
SK27.04.2016
SM27.04.2016
TR27.04.2016
GR28.07.2016
MT31.07.2016
PT29.08.2016
[2018/46]
Former [2018/38]HU06.07.2011
BG27.04.2016
CY27.04.2016
CZ27.04.2016
EE27.04.2016
HR27.04.2016
IS27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
MK27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SI27.04.2016
SK27.04.2016
SM27.04.2016
TR27.04.2016
GR28.07.2016
MT31.07.2016
PT29.08.2016
Former [2018/31]HU06.07.2011
CY27.04.2016
CZ27.04.2016
EE27.04.2016
HR27.04.2016
IS27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
MK27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SI27.04.2016
SK27.04.2016
SM27.04.2016
TR27.04.2016
GR28.07.2016
MT31.07.2016
PT29.08.2016
Former [2018/29]HU06.07.2011
CY27.04.2016
CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
MK27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SI27.04.2016
SK27.04.2016
SM27.04.2016
TR27.04.2016
GR28.07.2016
PT29.08.2016
Former [2018/28]HU06.07.2011
CY27.04.2016
CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
MK27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SI27.04.2016
SK27.04.2016
SM27.04.2016
GR28.07.2016
PT29.08.2016
Former [2017/37]CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SI27.04.2016
SK27.04.2016
SM27.04.2016
GR28.07.2016
PT29.08.2016
Former [2017/22]CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
MC27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SK27.04.2016
SM27.04.2016
GR28.07.2016
PT29.08.2016
Former [2017/11]CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SK27.04.2016
SM27.04.2016
GR28.07.2016
PT29.08.2016
Former [2017/10]CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
SK27.04.2016
GR28.07.2016
PT29.08.2016
Former [2017/09]CZ27.04.2016
EE27.04.2016
HR27.04.2016
LT27.04.2016
LV27.04.2016
PL27.04.2016
RO27.04.2016
RS27.04.2016
GR28.07.2016
PT29.08.2016
Former [2016/51]HR27.04.2016
LT27.04.2016
LV27.04.2016
PL27.04.2016
RS27.04.2016
GR28.07.2016
PT29.08.2016
Former [2016/50]HR27.04.2016
LT27.04.2016
LV27.04.2016
PL27.04.2016
RS27.04.2016
Former [2016/49]LT27.04.2016
PL27.04.2016
Former [2016/46]LT27.04.2016
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DOI:   http://dx.doi.org/10.1007/S10482-010-9418-4
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DOI:   http://dx.doi.org/10.1016/J.VASCN.2010.02.010
 [AD]  - KUIPERS ANNEKE ET AL, "NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US LNKD- DOI:10.1074/JBC.M312789200, (20040521), vol. 279, no. 21, ISSN 0021-9258, pages 22176 - 22182, XP002424517 [AD] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.M312789200
 [Y]  - LEENHOUTS K ET AL, "Anchoring of proteins to lactic acid bacteria", ANTONIE VAN LEEUWENHOEK, SPRINGER NETHERLANDS, DORDRECHT LNKD- DOI:10.1023/A:1002095802571, (19990701), vol. 76, no. 1-4, ISSN 0003-6072, pages 367 - 376, XP002493781 [Y] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1023/A:1002095802571
 [AD]  - MARRAFFINI LA ET AL, "SORTASES AND THE ART OF ANCHORING PROTEINS TO THE ENVELOPES OF GRAM-POSITIVE BACTERIA", MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, AMERICAN SOCIETY FOR MICROBIOLOGY, US LNKD- DOI:10.1128/MMBR.70.1.192-221.2006, (20060301), vol. 70, no. 1, ISSN 1092-2172, pages 192 - 221, XP002459580 [AD] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1128/MMBR.70.1.192-221.2006
 [A]  - TJALSMA H ET AL, "Signal peptide-dependent protein transport in Bacillus subtilis: A genome-based survey of the secretome", MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, AMERICAN SOCIETY FOR MICROBIOLOGY, US LNKD- DOI:10.1128/MMBR.64.3.515-547.2000, (20000901), vol. 64, no. 3, ISSN 1092-2172, pages 515 - 547, XP002227136 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1128/MMBR.64.3.515-547.2000
 [Y]  - MOLL G N ET AL, "A biological stabilization technology for peptide drugs: enzymatic introduction of thioether-bridges", DRUG DISCOVERY TODAY: TECHNOLOGIES, ELSEVIER, vol. 6, no. 1-4, doi:10.1016/J.DDTEC.2009.03.001, ISSN 1740-6749, (20090101), pages E13 - E18, (20090419), XP027503974 [Y] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ddtec.2009.03.001
 [A]  - LUBELSKI J ET AL, "Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin", CMLS CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHÄUSER-VERLAG, BA, (20071029), vol. 65, no. 3, ISSN 1420-9071, pages 455 - 476, XP019583821 [A] 1-17 * the whole document *
 [T]  - BOSMA TJIBBE ET AL, "Bacterial Display and Screening of Posttranslationally Thioether-Stabilized Peptides", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20111001), vol. 77, no. 19, ISSN 0099-2240, pages 6794 - 6801, XP009153580 [T] * the whole document *
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DOI:   http://dx.doi.org/10.1007/S10482-010-9418-4
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.