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Extract from the Register of European Patents

EP About this file: EP2598135

EP2598135 - TREATMENT OF COGNITIVE DISORDERS WITH CERTAIN ALPHA-7 NICOTINIC ACID RECEPTOR AGONISTS IN COMBINATION WITH ACETYLCHOLINESTERASE INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  14.10.2016
Database last updated on 31.05.2024
Most recent event   Tooltip14.10.2016Application deemed to be withdrawnpublished on 16.11.2016  [2016/46]
Applicant(s)For all designated states
EnVivo Pharmaceuticals, Inc.
500 Arsenal Street
Watertown MA 02472 / US
[2013/29]
Former [2013/23]For all designated states
Koenig, Gerhard
1662 Commonwealth Ave.
Newton, Massachusetts 02465 / US
For all designated states
Hilt, Dana
204 Clocktower Drive 205
Waltham, Massachusetts 02452 / US
For all designated states
Envivo Pharmaceuticals, Inc.
480 Arsenal Street Bldg. 1
Watertown, MA 02472 / US
Inventor(s)01 / KOENIG, Gerhard
1662 Commonwealth Ave.
Newton, Massachusetts 02465 / US
02 / HILT, Dana
204 Clocktower Drive 205
Waltham, Massachusetts 02452 / US
 [2013/23]
Representative(s)Holzwarth-Rochford, Andreas
Jones Day
Nextower
Thurn-und-Taxis-Platz 6
60313 Frankfurt am Main / DE
[2013/23]
Application number, filing date11748786.825.07.2011
WO2011US45206
Priority number, dateUS20100412353P10.11.2010         Original published format: US 412353 P
US20100411911P09.11.2010         Original published format: US 411911 P
US20100367672P26.07.2010         Original published format: US 367672 P
[2013/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012015749
Date:02.02.2012
Language:EN
[2012/05]
Type: A1 Application with search report 
No.:EP2598135
Date:05.06.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 02.02.2012 takes the place of the publication of the European patent application.
[2013/23]
Search report(s)International search report - published on:EP02.02.2012
ClassificationIPC:A61K31/27, A61K31/439, A61K31/445, A61K31/473, A61K31/55, A61P25/28
[2013/23]
CPC:
A61K31/439 (EP,US); A61K31/27 (EP,US); A61K31/325 (US);
A61K31/444 (US); A61K31/445 (EP,US); A61K31/473 (EP,US);
A61K31/501 (US); A61K31/55 (EP,US); A61K45/06 (EP,US);
A61P25/28 (EP); A61P43/00 (EP) (-)
C-Set:
A61K31/27, A61K2300/00 (EP,US);
A61K31/439, A61K2300/00 (US,EP);
A61K31/445, A61K2300/00 (US,EP);
A61K31/473, A61K2300/00 (US,EP);
A61K31/55, A61K2300/00 (EP,US)
(-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/23]
TitleGerman:BEHANDLUNG VON KOGNITIVEN STÖRUNGEN MIT BESTIMMTEN ALPHA-7-NIKOTINSÄUREREZEPTORAGONISTEN IN KOMBINATION MIT ACETYLCHOLINESTERASEHEMMERN[2013/23]
English:TREATMENT OF COGNITIVE DISORDERS WITH CERTAIN ALPHA-7 NICOTINIC ACID RECEPTOR AGONISTS IN COMBINATION WITH ACETYLCHOLINESTERASE INHIBITORS[2013/23]
French:TRAITEMENT DE TROUBLES COGNITIFS PAR CERTAINS AGONISTES DU RÉCEPTEUR ALPHA-7 DE L'ACIDE NICOTINIQUE EN COMBINAISON À DES INHIBITEURS D'ACÉTYLCHOLINESTÉRASE[2013/23]
Entry into regional phase22.02.2013National basic fee paid 
22.02.2013Designation fee(s) paid 
22.02.2013Examination fee paid 
Examination proceduredeletedCommunication of intention to grant the patent
22.02.2013Amendment by applicant (claims and/or description)
22.02.2013Examination requested  [2013/23]
03.12.2015Despatch of a communication from the examining division (Time limit: M06)
14.06.2016Application deemed to be withdrawn, date of legal effect  [2016/46]
12.07.2016Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2016/46]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  03.12.2015
Fees paidRenewal fee
25.07.2013Renewal fee patent year 03
14.07.2014Renewal fee patent year 04
27.07.2015Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.07.201606   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XI]WO2009018505  (TARGACEPT INC [US], et al) [X] 1-7,25-29 * page 14, paragraph last - page 15, line 4 * * page 53, paragraph last - page 54 * * claims 1-26 * [I] 8-24,30-38;
 [XI]  - SABBAGH ET AL, "Drug development for Alzheimer's disease: Where are we now and where are we headed?", THE AMERICAN JOURNAL OF GERIATRIC PHARMACOTHERAPY, EXCERPTA MEDICA, vol. 7, no. 3, doi:10.1016/J.AMJOPHARM.2009.06.003, ISSN 1543-5946, (20090601), pages 167 - 185, (20090601), XP026321498 [X] 1-7,25-29 * page 177, column r, paragraph 2 * [I] 8-24,30-38

DOI:   http://dx.doi.org/10.1016/j.amjopharm.2009.06.003
 [XI]  - BITNER R SCOTT ET AL, "In Vivo Pharmacological Characterization of a Novel Selective alpha 7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, (20100526), vol. 334, no. 3, ISSN 0022-3565, pages 875 - 886 URL, XP055008274 [X] 1-7,25-29 * page 880, column r, paragraph 5 - page 881, column l, paragraph 1 * [I] 8-24,30-38

DOI:   http://dx.doi.org/10.1124/jpet.110.167213
 [Y]  - REZVANI A H ET AL, "Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats", PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, OXFORD, GB, vol. 33, no. 2, doi:10.1016/J.PNPBP.2008.11.018, ISSN 0278-5846, (20090317), pages 269 - 275, (20081213), XP025952929 [Y] 1-38 * Discussion; page 274 *

DOI:   http://dx.doi.org/10.1016/j.pnpbp.2008.11.018
 [Y]  - WALLACE T L ET AL, "R3487/MEM 3454, a novel nicotinic alpha 7 receptor partial agonist, improves attention and working memory performance in cynomolgus macaques", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB, vol. 78, no. 7, doi:10.1016/J.BCP.2009.06.060, ISSN 0006-2952, (20091001), page 912, (20090813), XP026467517 [Y] 1-38 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bcp.2009.06.060
 [Y]  - FEUERBACH D ET AL, "The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain", NEUROPHARMACOLOGY, PERGAMON PRESS, OXFORD, GB, vol. 56, no. 1, doi:10.1016/J.NEUROPHARM.2008.08.025, ISSN 0028-3908, (20090101), pages 254 - 263, (20080828), XP025846225 [Y] 1-38 * abstract *

DOI:   http://dx.doi.org/10.1016/j.neuropharm.2008.08.025
 [Y]  - HAUSER T A ET AL, "TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB, vol. 78, no. 7, doi:10.1016/J.BCP.2009.05.030, ISSN 0006-2952, (20091001), pages 803 - 812, (20090529), XP026467477 [Y] 1-38 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bcp.2009.05.030
ExaminationUS2005245504
 US2008306081
by applicantWO2004029050
 US6780861
 WO2005092890
 US6953855
 US2005245531
 WO2006065233
 WO2007038367
    - HAUSER ET AL., BIOCHEMICAL PHARMACOLOGY, (2009), vol. 78, page 803
    - Handbook of Pharmaceutical Salts, Properties, Selection and Use, WILEY-VCH
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.