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Extract from the Register of European Patents

EP About this file: EP2548958

EP2548958 - AGENT FOR IMPROVING GENE TRANSFER EFFICIENCY TO MAMMALIAN CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  28.09.2018
Database last updated on 05.10.2024
FormerThe patent has been granted
Status updated on  20.10.2017
FormerGrant of patent is intended
Status updated on  04.07.2017
FormerExamination is in progress
Status updated on  09.06.2017
FormerGrant of patent is intended
Status updated on  30.05.2017
FormerExamination is in progress
Status updated on  05.04.2017
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL, IS		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Yamaguchi University
1677-1, Yoshida Yamaguchi-shi
Yamaguchi 753-8511 / JP
[2013/04]
Inventor(s)01 / AKADA, Rinji
c/o Faculty of Engineering
Yamaguchi University
16-1 Tokiwadai 2-chome
Ube-shi Yamaguchi 755-8611 / JP
02 / NAKAMURA, Mikiko
c/o Faculty of Engineering
Yamaguchi University
16-1 Tokiwadai 2-chome
Ube-shi Yamaguchi 755-8611 / JP
 [2013/04]
Representative(s)Griffin, Philippa Jane, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2017/47]Griffin, Philippa Jane, et al
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
Former [2013/04]Griffin, Philippa Jane, et al
Mathys & Squire LLP 120 Holborn London
EC1N 2SQ / GB
Application number, filing date11755871.813.03.2011
[2017/47]
WO2011JP01449
Priority number, dateJP2010005773215.03.2010         Original published format: JP 2010057732
[2013/04]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011114678
Date:22.09.2011
Language:JA
[2011/38]
Type: A1 Application with search report 
No.:EP2548958
Date:23.01.2013
Language:EN
[2013/04]
Type: B1 Patent specification 
No.:EP2548958
Date:22.11.2017
Language:EN
[2017/47]
Search report(s)International search report - published on:JP22.09.2011
(Supplementary) European search report - dispatched on:EP02.09.2013
ClassificationIPC:C12N15/09, C12N15/88
[2013/40]
CPC:
C12N15/88 (EP,US); C12N15/90 (KR)
Former IPC [2013/04]C12N15/09
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/04]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:MITTEL FÜR VERBESSERTE GENTRANSFER-EFFIZIENZ IN SÄUGETIERZELLEN[2013/04]
English:AGENT FOR IMPROVING GENE TRANSFER EFFICIENCY TO MAMMALIAN CELLS[2013/04]
French:AGENT POUR L'AMÉLIORATION DE L'EFFICACITÉ DE TRANSFERT GÉNIQUE DANS DES CELLULES DE MAMMIFÈRE[2013/04]
Entry into regional phase10.09.2012Translation filed 
10.09.2012National basic fee paid 
10.09.2012Search fee paid 
10.09.2012Designation fee(s) paid 
10.09.2012Examination fee paid 
Examination procedure22.09.2011Request for preliminary examination filed
International Preliminary Examining Authority: JP
10.09.2012Examination requested  [2013/04]
11.03.2014Amendment by applicant (claims and/or description)
05.08.2015Despatch of a communication from the examining division (Time limit: M06)
08.12.2015Reply to a communication from the examining division
03.04.2017Despatch of a communication from the examining division (Time limit: M02)
04.04.2017Reply to a communication from the examining division
31.05.2017Communication of intention to grant the patent
01.06.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
04.07.2017Communication of intention to grant the patent
16.10.2017Fee for grant paid
16.10.2017Fee for publishing/printing paid
16.10.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  05.08.2015
Opposition(s)23.08.2018No opposition filed within time limit [2018/44]
Fees paidRenewal fee
26.03.2013Renewal fee patent year 03
21.03.2014Renewal fee patent year 04
24.03.2015Renewal fee patent year 05
25.03.2016Renewal fee patent year 06
24.03.2017Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU13.03.2011
AL22.11.2017
AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
MK22.11.2017
NL22.11.2017
PL22.11.2017
PT22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
TR22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
MT13.03.2018
IS22.03.2018
BE31.03.2018
CH31.03.2018
LI31.03.2018
[2020/33]
Former [2020/31]HU13.03.2011
AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
MK22.11.2017
NL22.11.2017
PL22.11.2017
PT22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
TR22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
MT13.03.2018
BE31.03.2018
CH31.03.2018
LI31.03.2018
Former [2020/27]HU13.03.2011
AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
PT22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
TR22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
MT13.03.2018
BE31.03.2018
CH31.03.2018
LI31.03.2018
Former [2020/16]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
TR22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
MT13.03.2018
BE31.03.2018
CH31.03.2018
LI31.03.2018
Former [2020/08]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
MT13.03.2018
BE31.03.2018
CH31.03.2018
LI31.03.2018
Former [2019/12]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
BE31.03.2018
CH31.03.2018
LI31.03.2018
Former [2019/09]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
IE13.03.2018
LU13.03.2018
Former [2019/04]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
LU13.03.2018
Former [2018/52]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
MC22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SI22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
Former [2018/40]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
NL22.11.2017
PL22.11.2017
RO22.11.2017
RS22.11.2017
SE22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
Former [2018/39]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
IT22.11.2017
LT22.11.2017
LV22.11.2017
NL22.11.2017
PL22.11.2017
RS22.11.2017
SE22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
Former [2018/37]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
LT22.11.2017
LV22.11.2017
NL22.11.2017
PL22.11.2017
RS22.11.2017
SE22.11.2017
SK22.11.2017
SM22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
Former [2018/35]AT22.11.2017
CY22.11.2017
CZ22.11.2017
DK22.11.2017
EE22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
LT22.11.2017
LV22.11.2017
NL22.11.2017
RS22.11.2017
SE22.11.2017
SK22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
Former [2018/24]AT22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
LT22.11.2017
LV22.11.2017
NL22.11.2017
RS22.11.2017
SE22.11.2017
BG22.02.2018
NO22.02.2018
GR23.02.2018
Former [2018/23]AT22.11.2017
ES22.11.2017
FI22.11.2017
HR22.11.2017
LT22.11.2017
NL22.11.2017
RS22.11.2017
SE22.11.2017
NO22.02.2018
GR23.02.2018
Former [2018/22]ES22.11.2017
FI22.11.2017
LT22.11.2017
NL22.11.2017
NO22.02.2018
Documents cited:Search[A]  - KOUMBI ET AL, "Detailed studies on the mechanism and factors mediating lipofection potency of cationic phosphonolipid-based gene transfer into human cells", BLOOD CELLS, MOLECULES AND DISEASES, LAJOLLA, US, (20080212), vol. 40, no. 2, doi:10.1016/J.BCMD.2007.10.054, ISSN 1079-9796, pages 272 - 273, XP022477852 [A] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bcmd.2007.10.054
 [A]  - JUNG HEE JUNG ET AL, "Carassius auratus-originated recombinant histone H1C-terminal peptide as gene delivery material", BIOTECHNOLOGY PROGRESS, (200801), vol. 24, no. 1, ISSN 8756-7938, pages 17 - 22, XP002711664 [A] 1-9 * page 17 - page 19 *

DOI:   http://dx.doi.org/10.1021/BP070069B
 [A]  - CHABAUD PAULINE ET AL, "Cationic nucleoside lipids for gene delivery", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US, vol. 17, no. 2, doi:10.1021/BC050162Q, ISSN 1043-1802, (20060301), pages 466 - 472, (20060208), XP002490412 [A] 1-9 * page 466 - page 468 * * page 471; figures 5, 6 *

DOI:   http://dx.doi.org/10.1021/bc050162q
 [A]  - NIMESH S ET AL, "Polyethylenimine nanoparticles as efficient transfecting agents for mammalian cells", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 110, no. 2, doi:10.1016/J.JCONREL.2005.10.014, ISSN 0168-3659, (20060110), pages 457 - 468, (20060110), XP024957400 [A] 1-9 * page 457 - page 460; figure 6 * * page 465 - page 466 *

DOI:   http://dx.doi.org/10.1016/j.jconrel.2005.10.014
International search[A]JP2008540601  (CUREVAC GMBH);
 [A]WO2007046356  (OTSUKA PHARMA CO LTD [JP], et al)
 [X]  - ZAITSEV S. ET AL, "Polyelectrolyte Nanoparticles Mediate Vascular Gene Delivery", PHARMACEUT. RES., (2004), vol. 21, no. 9, pages 1656 - 1661
 [A]  - GESLAIN R. ET AL, "Functional Analysis of Human tRNA Isodecoders", J. MOL. BIOL., (200912), vol. 396, pages 821 - 831
by applicantJP2005269920
 JP2009195197
    - JOURNAL OF APPLIED POLYMER SCIENCE, (2009), vol. 114, pages 2221 - 2225
    - THE JOURNAL OF GENE MEDICINE, (2001), vol. 3, pages 115 - 124
    - "Molecular Cloning", Current Protocols in Molecular Biology, JOHN WILEY & SONS, (1987), pages 1 - 38
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.