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Extract from the Register of European Patents

EP About this file: EP2633316

EP2633316 - DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  20.10.2017
Database last updated on 03.09.2024
FormerExamination is in progress
Status updated on  18.04.2017
Most recent event   Tooltip20.10.2017Application deemed to be withdrawnpublished on 22.11.2017  [2017/47]
Applicant(s)For all designated states
Nilsson, Jonas
Bokskogsbacken 57
422 56 Hisings-Backa / SE
For all designated states
Halim, Adnan
Berättelsegatan 10
422 42 Hisings-Backa / SE
For all designated states
Larson, Göran
Olivedalsgatan 19
413 10 Göteborg / SE
For all designated states
Blennow, Kaj
Klyvsågsgatan 1
416 79 Göteborg / SE
For all designated states
Brinkmalm, Gunnar
Gundas Gata 85
431 51 Mölndal / SE
For all designated states
Portelius, Erik
Ollebergsvägen 4
511 68 Hyssna / SE
For all designated states
Zetterberg, Henrik
Rullstensvägen 10
435 41 Mölnlycke / SE
[2013/36]
Inventor(s)01 / see applicant
...
 [2013/36]
Representative(s)Brann AB
P.O. Box 3690
Sveavägen 63
103 59 Stockholm / SE
[N/P]
Former [2013/46]Brann AB
P.O. Box 12246
102 26 Stockholm / SE
Former [2013/36]Holmberg, Nils Anders Patrik, et al
BRANN AB
P.O. Box 12246
102 26 Stockholm / SE
Application number, filing date11775997.728.10.2011
WO2011EP69006
Priority number, dateUS20100455891P28.10.2010         Original published format: US 455891 P
[2013/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012056008
Date:03.05.2012
Language:EN
[2012/18]
Type: A1 Application with search report 
No.:EP2633316
Date:04.09.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 03.05.2012 takes the place of the publication of the European patent application.
[2013/36]
Search report(s)International search report - published on:EP03.05.2012
ClassificationIPC:G01N33/53
[2013/36]
CPC:
G01N33/6896 (EP,US); A61K39/0007 (US); C07K16/18 (US);
H01J49/0027 (US); G01N2333/4709 (EP,US); G01N2440/38 (US);
G01N2800/2821 (EP,US); G01N2800/50 (US); G01N2800/52 (US);
Y10T436/24 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/36]
TitleGerman:DIAGNOSE UND BEHANDLUNG VON MORBUS ALZHEIMER[2013/36]
English:DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE[2013/36]
French:DIAGNOSTIC ET TRAITEMENT DE LA MALADIE D'ALZHEIMER[2013/36]
Entry into regional phase24.05.2013National basic fee paid 
24.05.2013Designation fee(s) paid 
24.05.2013Examination fee paid 
Examination procedure24.05.2013Examination requested  [2013/36]
19.12.2013Amendment by applicant (claims and/or description)
15.10.2014Despatch of a communication from the examining division (Time limit: M04)
17.02.2015Reply to a communication from the examining division
03.05.2016Despatch of a communication from the examining division (Time limit: M04)
01.09.2016Reply to a communication from the examining division
06.04.2017Despatch of a communication from the examining division (Time limit: M02)
17.06.2017Application deemed to be withdrawn, date of legal effect  [2017/47]
14.07.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2017/47]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.10.2014
Fees paidRenewal fee
15.10.2013Renewal fee patent year 03
20.10.2014Renewal fee patent year 04
12.10.2015Renewal fee patent year 05
25.10.2016Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]US6410598  (VITEK MICHAEL P [US], et al) [X] 20 * abstract * * column 13; example 1 * * column 25 - column 31 *;
 [A]US5461143  (WONG CHI-HUEY [US], et al) [A] 1-32,36 * the whole document *;
 [A]WO0215721  (ARIMEDES BIOTECHNOLOGY GMBH [DE], et al) [A] 1-32,36 * claim 11 *;
 [XA]  - PERDIVARA IRINA ET AL, "Elucidation of O-Glycosylation Structures of the beta-Amyloid Precursor Protein by Liquid Chromatography-Mass Spectrometry Using Electron Transfer Dissociation and Collision Induced Dissociation", JOURNAL OF PROTEOME RESEARCH, (200902), vol. 8, no. 2, Sp. Iss. SI, ISSN 1535-3893, pages 631 - 642, XP002666309 [X] 28,29 * the whole document * * page 631, column 1, paragraph 1; figure 1 * [A] 1-19,21,32,36

DOI:   http://dx.doi.org/10.1021/PR800758G
 [A]  - ZIMMERMANN M ET AL, "Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines", JOURNAL OF NEUROCHEMISTRY, WILEY INTERSCIENCE, NEW YORK, NY, US, (20040101), vol. 90, doi:10.1111/J.1471-4159.2004.02680.X, ISSN 0022-3042, pages 1489 - 1499, XP002998428 [A] 1-19,21,32,36 * abstract *

DOI:   http://dx.doi.org/10.1111/j.1471-4159.2004.02680.x
by applicantUS5461143
 US5580859
 US4235871
 US4501728
 US4837028
 US4957773
 US4603044
    - BLENNOW ET AL., NAT REV NEUROL, (2010), vol. 6, pages 131 - 144
    - BLUM, BARNSTABLE, PNAS, (1987), vol. 84, pages 8716 - 8720
    - SATO ET AL., JBC, (1995), vol. 270, pages 18923 - 28
    - Essentials of Glycobiology, (2009), page 132
    - PRAMANIK, J AM. CHEM. SOC.
    - KUMMER, NEURON, (20110908), vol. 71, pages 833 - 44
    - ZARSCHLER ET AL., GLYCOBIOLOGY, (2010), vol. 20, no. 6, pages 787 - 98
    - FANTINI, YAHI, EXP REV MOL MED, (2010), vol. 12, pages 1 - 22
    - DATTA, PAULSON, INDIAN J. BIOCHEM. BIOPHYS., (1997), vol. 34, pages 157 - 65
    - GUO, WANG, APPL. BIOCHEM. BIOTECHNOL., (1997), vol. 68, pages 1 - 20
    - TSUJI, J. BIOCHEM. (TOKYO, (1996), vol. 120, pages 1 - 13
    - HARDUIN-LEPERS ET AL., GLYCOBIOLOGY, (1995), vol. 5, pages 741 - 758
    - VAGHEFI ET AL., J. MED. CHEM., (1987), vol. 30, pages 1383 - 1391
    - VAGHEFI ET AL., J. MED CHEM., (1987), vol. 30, pages 1391 - 1399
    - CAMARASA ET AL., J. MED. CHEM., (1985), vol. 28, pages 40 - 46
    - DECLERCQ, BIOCHEM. J., (1982), vol. 205, page 1
    - SCHAUB ET AL., GLYCOCONJUGATE J., (1998), vol. 15, pages 345 - 354
    - PAULSON ET AL., J. BIOL. CHEM., (1978), vol. 253, pages 5617 - 5624
    - THORENS ET AL., NATURE, (1986), vol. 321, page 618
    - WHITE ET AL., BIOCHEM., (1990), vol. 29, pages 2740 - 2747
    - "Measurement of Enzyme Activity", ROSSOMANDO, Guide to Protein Purification, Vol. 182, Methods in Enzymology, (1990), vol. 182
    - HELENE, C., TOULME, J., BIOCHIM. BIOPHYS. ACTA, (1990), vol. 1049, pages 99 - 125
    - WICKSTROM E. L. ET AL., PROC. NAT'L. ACAD. SCI. USA, (1988), vol. 85, pages 1028 - 1032
    - HAREL-BELLAN ET AL., EXP. MED., (1988), vol. 168, pages 2309 - 2318
    - ADACHI M ET AL., J EXP MED, (1988), vol. 167, pages 323 - 331
    - CEBULLA CM ET AL., TRANSPLANTATION, (2000), vol. 69, pages 1202 - 1209
    - HIRAIWA N ET AL., BLOOD, (2003), vol. 101, pages 3615 - 3621
    - NORDEN R ET AL., GLYCOBIOLOGY, (2009), vol. 19, pages 776 - 88
    - SZOKA ET AL., ANN. REV. BIOPHYS. BIOENG., (1980), vol. 9, page 467
    - HANSSON, 0., ZETTERBERG, H., BUCHHAVE, P., LONDOS, E., BLENNOW, K., MINTHON, L., "Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study", LANCET NEUROLOGY, (2006), vol. 5, pages 228 - 234
    - PORTELIUS, E., TRAN, A. J., ANDREASSON, U., PERSSON, R., BRINKMALM, G., ZETTERBERG, H., BLENNOW, K., WESTMAN-BRINKMALM, A., "Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry", J PROTEOME RES, (2007), vol. 6, pages 4433 - 4439
    - BLENNOW, K., HAMPEL, H., WEINER, M., ZETTERBERG, H., "Cerebrospinal fluid and plasma biomarkers in Alzheimer disease", NAT REV NEUROL, (2010), vol. 6, pages 131 - 144
    - HORIKOSHI ET AL., BIOCHEM BIOPHYS RES COMMUN., (2004), vol. 319, no. 3, pages 733 - 7
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.