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Extract from the Register of European Patents

EP About this file: EP2573067

EP2573067 - AROMATIC BUTAN-2-OL COMPOUNDS, PREPARATION METHODS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.08.2019
Database last updated on 15.06.2024
FormerThe patent has been granted
Status updated on  07.09.2018
FormerGrant of patent is intended
Status updated on  24.04.2018
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
No. 27, Taiping Road
Haidian District
Beijing 100-850 / CN
[2013/41]
Former [2013/13]For all designated states
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.
No. 27 Taiping Road
Haidian District
Beijing 100850 / CN
Inventor(s)01 / LI, Song
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
02 / ZHONG, Wu
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
03 / LIU, Ping
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
04 / XIAO, Junhai
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
05 / ZHENG, Zhibing
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
06 / XIE, Yunde
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
07 / ZHAO, Guoming
No. 27, Taiping Road
Haidian
Beijing 100850 / CN
08 / WANG, Xiaokui
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
09 / WANG, Lili
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
10 / LI, Xingzhou
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
11 / ZHOU, Xinbo
No. 27, Taiping Road
Haidian District
Beijing 100850 / CN
 [2013/13]
Representative(s)Weickmann & Weickmann PartmbB
Postfach 860 820
81635 München / DE
[2018/41]
Former [2013/13]Dey, Michael, et al
Weickmann & Weickmann Patentanwälte Postfach 860820
81635 München / DE
Application number, filing date11782849.116.05.2011
[2018/41]
WO2011CN00849
Priority number, dateCN20101017378517.05.2010         Original published format: CN201010173785
[2013/13]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011143932
Date:24.11.2011
Language:ZH
[2011/47]
Type: A1 Application with search report 
No.:EP2573067
Date:27.03.2013
Language:EN
[2013/13]
Type: B1 Patent specification 
No.:EP2573067
Date:10.10.2018
Language:EN
[2018/41]
Search report(s)International search report - published on:CN24.11.2011
(Supplementary) European search report - dispatched on:EP26.09.2014
ClassificationIPC:C07C215/62, C07C217/72, A61K31/137, A61P31/06
[2014/44]
CPC:
C07C217/72 (EP,US); A61K31/137 (EP,US); A61P31/06 (EP);
C07C213/00 (US); C07C215/62 (EP,US)
Former IPC [2013/13]C07C215/30, C07C213/08, A61K31/137, A61P31/06
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/13]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:AROMATISCHE BUTAN-2-OL-VERBINDUNGEN SOWIE HERSTELLUNGSVERFAHREN UND VERWENDUNGEN DAFÜR[2013/13]
English:AROMATIC BUTAN-2-OL COMPOUNDS, PREPARATION METHODS AND USES THEREOF[2013/13]
French:COMPOSÉS AROMATIQUES DE BUTAN-2-OL, LEURS PROCÉDÉS DE PRÉPARATION ET LEURS UTILISATIONS[2013/13]
Entry into regional phase23.11.2012Translation filed 
23.11.2012National basic fee paid 
23.11.2012Search fee paid 
23.11.2012Designation fee(s) paid 
23.11.2012Examination fee paid 
Examination procedure23.11.2012Examination requested  [2013/13]
21.04.2015Amendment by applicant (claims and/or description)
25.09.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the invitation to file a copy of earlier search results or a statement of non-availability not received in time
30.09.2015Request for decision received: Application is deemed to be withdrawn
26.11.2015Result of request for decision (Application is deemed to be withdrawn): Request accepted
25.04.2018Communication of intention to grant the patent
29.08.2018Fee for grant paid
29.08.2018Fee for publishing/printing paid
29.08.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.04.2018
Opposition(s)11.07.2019No opposition filed within time limit [2019/38]
Fees paidRenewal fee
10.05.2013Renewal fee patent year 03
27.03.2014Renewal fee patent year 04
12.05.2015Renewal fee patent year 05
10.05.2016Renewal fee patent year 06
10.05.2017Renewal fee patent year 07
11.05.2018Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU16.05.2011
AL10.10.2018
AT10.10.2018
CY10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
MK10.10.2018
MT10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
IE16.05.2019
LU16.05.2019
BE31.05.2019
CH31.05.2019
LI31.05.2019
[2022/31]
Former [2021/34]HU16.05.2011
AL10.10.2018
AT10.10.2018
CY10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
MT10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
IE16.05.2019
LU16.05.2019
BE31.05.2019
CH31.05.2019
LI31.05.2019
Former [2021/33]HU16.05.2011
AL10.10.2018
AT10.10.2018
CY10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
IE16.05.2019
LU16.05.2019
BE31.05.2019
CH31.05.2019
LI31.05.2019
Former [2021/26]AL10.10.2018
AT10.10.2018
CY10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
IE16.05.2019
LU16.05.2019
BE31.05.2019
CH31.05.2019
LI31.05.2019
Former [2020/26]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
IE16.05.2019
LU16.05.2019
BE31.05.2019
CH31.05.2019
LI31.05.2019
Former [2020/21]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
IE16.05.2019
LU16.05.2019
CH31.05.2019
LI31.05.2019
Former [2020/17]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
TR10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
LU16.05.2019
CH31.05.2019
LI31.05.2019
Former [2020/11]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
LU16.05.2019
CH31.05.2019
LI31.05.2019
Former [2020/07]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
MC10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/50]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SI10.10.2018
SK10.10.2018
SM10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/40]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SK10.10.2018
SM10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/37]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
EE10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RO10.10.2018
RS10.10.2018
SE10.10.2018
SM10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/35]AL10.10.2018
AT10.10.2018
CZ10.10.2018
DK10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RS10.10.2018
SE10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/34]AL10.10.2018
AT10.10.2018
DK10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
IT10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RS10.10.2018
SE10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/26]AL10.10.2018
AT10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RS10.10.2018
SE10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
PT10.02.2019
Former [2019/25]AT10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
RS10.10.2018
SE10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
Former [2019/24]AT10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
SE10.10.2018
BG10.01.2019
NO10.01.2019
GR11.01.2019
IS10.02.2019
Former [2019/23]AT10.10.2018
ES10.10.2018
FI10.10.2018
HR10.10.2018
LT10.10.2018
LV10.10.2018
NL10.10.2018
PL10.10.2018
BG10.01.2019
NO10.01.2019
IS10.02.2019
Former [2019/22]FI10.10.2018
LT10.10.2018
NL10.10.2018
PL10.10.2018
BG10.01.2019
NO10.01.2019
IS10.02.2019
Former [2019/21]FI10.10.2018
LT10.10.2018
NL10.10.2018
NO10.01.2019
IS10.02.2019
Former [2019/20]LT10.10.2018
NL10.10.2018
NO10.01.2019
Former [2019/17]NL10.10.2018
Documents cited:Search[Y]WO2004011436  (JANSSEN PHARMACEUTICA NV [BE], et al) [Y] 1-12 * the whole document *;
 [Y]  - BURGER A ED - JUCKER E, Isosterism and bioisosterism in drug design, PROGRESS IN DRUG RESEARCH. FORTSCHRITTE DER ARNEIMITTELFORSCHUNG. PROGRES DES RECHERCHES PHARMACEUTIQUES; [PROGRESS IN DRUG RESEARCH], BASEL, BIRKHAUSER VERLAG, CH, PAGE(S) 287 - 371, (19910101), XP002096229 [Y] 1-12 * see text of bottom p.306 and figures of top of p.307; page 306, paragraph last - page 307 *
International search[A]CN1671667  (JANSSEN PHARMACEUTICA NV [BE]);
 [A]CN1976704  (JANSSEN PHARMACEUTICA NV [BE]);
 [XP]  - LIU, PING ET AL., "(1R*,2R*)-1-(4-Chlorophenyl)-4-dimethylamino-1-(3- methoxy-2-naphthyl)-2-(1-naphthyl)butan-2-ol", ACTA CRYST., (20100605), vol. E66, page O1571, XP055108036

DOI:   http://dx.doi.org/10.1107/S160053681001891X
 [X]  - LIU, PING ET AL., "(1R*,2R*)-I-(7-Bromo-3-methoxy-naphthalen-2-yl)- 4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol", ACTA CRYST., (20100213), vol. E66, page O636, XP055108039

DOI:   http://dx.doi.org/10.1107/S1600536810005209
 [Y]  - LUCAS SIMON ET AL., "Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach", J. MED. CHEM., (2008), vol. 51, no. 19, pages 6138 - 6149, XP055100489

DOI:   http://dx.doi.org/10.1021/jm800683c
 [Y]  - IRAN HUU-ANH ET AL., "O-Ethoxycarbonylmethoxy esters of homocalix[n]naphthalenes: synthesis and recognition behaviour towards alkali cations", J INCL PHENOM MACROCYCL CHEM., (2008), vol. 60, pages 43 - 49, XP019574937
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.