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Extract from the Register of European Patents

EP About this file: EP2608797

EP2608797 - BONE MARROW DERIVED CD271 PRECURSOR CELLS FOR CARDIAC REPAIR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.07.2016
Database last updated on 31.08.2024
Most recent event   Tooltip19.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 21.11.2018  [2018/47]
Applicant(s)For all designated states
University of Miami
Office of Technology Transfer
1400 N.W. 10th Avenue Suite 906
Miami, FL 33136 / US
[2013/27]
Inventor(s)01 / HARE, Joshua, M.
6010 Aqua Path
Miami Beach, FL 33141 / US
02 / McNIECE, Ian, K.
821 Majorca Avenue
Coral Gables, FL 33134 / US
 [2013/27]
Representative(s)Inspicos P/S
Agern Allé 24
2970 Hørsholm / DK
[N/P]
Former [2015/39]Inspicos A/S
Kogle Allé 2
P.O. Box 45
2970 Hørsholm / DK
Former [2013/27]Inspicos A/S
Kogle Allé 2 P.O. Box 45
2970 Hørsholm / DK
Application number, filing date11820774.529.08.2011
[2015/39]
WO2011US49542
Priority number, dateUS20100377661P27.08.2010         Original published format: US 377661 P
[2013/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012027740
Date:01.03.2012
Language:EN
[2012/09]
Type: A1 Application with search report 
No.:EP2608797
Date:03.07.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 01.03.2012 takes the place of the publication of the European patent application.
[2013/27]
Type: B1 Patent specification 
No.:EP2608797
Date:23.09.2015
Language:EN
[2015/39]
Search report(s)International search report - published on:US01.03.2012
(Supplementary) European search report - dispatched on:EP02.01.2014
ClassificationIPC:A61K35/12
[2013/27]
CPC:
A61K35/28 (EP,US); A61K35/12 (KR); A61P9/00 (EP);
A61P9/04 (EP); A61P9/10 (EP); A61P9/12 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/27]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:AUS KNOCHENMARK GEWONNENE CD271-VORLÄUFERZELLEN ZUR HERZREPARATUR[2013/27]
English:BONE MARROW DERIVED CD271 PRECURSOR CELLS FOR CARDIAC REPAIR[2013/27]
French:CELLULES PRÉCURSEUR CD271 ISSUES DE LA MOELLE OSSEUSE POUR UNE RÉPARATION CARDIAQUE[2013/27]
Entry into regional phase27.03.2013National basic fee paid 
27.03.2013Search fee paid 
27.03.2013Designation fee(s) paid 
27.03.2013Examination fee paid 
Examination procedure27.03.2013Examination requested  [2013/27]
24.07.2014Amendment by applicant (claims and/or description)
24.10.2014Despatch of a communication from the examining division (Time limit: M04)
26.02.2015Reply to a communication from the examining division
07.04.2015Communication of intention to grant the patent
13.08.2015Fee for grant paid
13.08.2015Fee for publishing/printing paid
13.08.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  24.10.2014
Opposition(s)24.06.2016No opposition filed within time limit [2016/35]
Fees paidRenewal fee
02.09.2013Renewal fee patent year 03
13.08.2014Renewal fee patent year 04
10.08.2015Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU29.08.2011
AL23.09.2015
AT23.09.2015
BE23.09.2015
BG23.09.2015
CY23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
MC23.09.2015
MK23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
SM23.09.2015
TR23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
[2018/47]
Former [2018/38]HU29.08.2011
AT23.09.2015
BE23.09.2015
BG23.09.2015
CY23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
MC23.09.2015
MK23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
SM23.09.2015
TR23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2018/31]HU29.08.2011
AT23.09.2015
BE23.09.2015
CY23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
MC23.09.2015
MK23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
SM23.09.2015
TR23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2018/29]HU29.08.2011
AT23.09.2015
BE23.09.2015
CY23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
MC23.09.2015
MK23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
SM23.09.2015
TR23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2018/28]HU29.08.2011
AT23.09.2015
BE23.09.2015
CY23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
MC23.09.2015
MK23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
SM23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2017/23]AT23.09.2015
BE23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
MC23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2017/03]AT23.09.2015
BE23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2016/49]AT23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SI23.09.2015
SK23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2016/39]AT23.09.2015
CZ23.09.2015
DK23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SK23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2016/24]AT23.09.2015
CZ23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
PL23.09.2015
RO23.09.2015
RS23.09.2015
SK23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
PT25.01.2016
Former [2016/23]CZ23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
RO23.09.2015
RS23.09.2015
SK23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
Former [2016/22]CZ23.09.2015
EE23.09.2015
FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
RS23.09.2015
NO23.12.2015
GR24.12.2015
IS23.01.2016
Former [2016/14]FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
NL23.09.2015
RS23.09.2015
NO23.12.2015
GR24.12.2015
Former [2016/10]FI23.09.2015
HR23.09.2015
LT23.09.2015
LV23.09.2015
RS23.09.2015
NO23.12.2015
GR24.12.2015
Former [2016/09]FI23.09.2015
LT23.09.2015
LV23.09.2015
NO23.12.2015
GR24.12.2015
Former [2016/08]LT23.09.2015
NO23.12.2015
Former [2016/07]LT23.09.2015
Documents cited:Search[X]  - QUEVEDO HENRY C ET AL, Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 18 AUG 2009, VOL. 106, NR. 33, PAGE(S) 14022 - 14027, (20090818), ISSN 1091-6490, XP002717518 [X] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1073/PNAS.0903201106
 [I]  - AOYAGI KAZUYA ET AL, Significance of CD271 in bone marrow mesenchymal stem cells--changes by cryopreservation., THE JOURNAL OF CRANIOFACIAL SURGERY MAY 2010, VOL. 21, NR. 3, PAGE(S) 666 - 678, (201005), ISSN 1536-3732, XP009174872 [I] 1-16 * abstract *

DOI:   http://dx.doi.org/10.1097/SCS.0b013e3181d7a792
 [IP]  - FLORES-TORALES EDGARDO ET AL, The CD271 expression could be alone for establisher phenotypic marker in Bone Marrow derived mesenchymal stem cells., FOLIA HISTOCHEMICA ET CYTOBIOLOGICA / POLISH ACADEMY OF SCIENCES, POLISH HISTOCHEMICAL AND CYTOCHEMICAL SOCIETY DEC 2010, VOL. 48, NR. 4, PAGE(S) 682 - 686, (201012), ISSN 1897-5631, XP002717520 [IP] 1-16 * abstract * * Conclusions *

DOI:   http://dx.doi.org/10.2478/VL0042-010-0063-6
 [X]  - ISO Y ET AL, "CD271 IDENTIFIES HUMAN BONE MARROW STEM/PROGENITOR CELLS WITH A PROANGIOGENIC POTENTIAL AND CIRCULATING PROGENITOR CELLS MOBILIZED AFTER ACUTE MYOCARDIAL INFARCTION", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER, NEW YORK, NY, US, vol. 55, no. 10, ISSN 0735-1097, (20100309), (20100309), XP027002485 [X] 1-16 * the whole document *
 [X]  - BÜHRING HANS-JÖRG ET AL, Novel markers for the prospective isolation of human MSC., ANNALS OF THE NEW YORK ACADEMY OF SCIENCES JUN 2007, VOL. 1106, PAGE(S) 262 - 271, (200706), ISSN 0077-8923, XP002717521 [X] 1-16 * abstract *

DOI:   http://dx.doi.org/10.1196/ANNALS.1392.000
 [XP]  - GHODSIZAD A ET AL, Application of CD271+ human bone marrow-derived: Stem cells for ischaemic heart disease therapy, EUROPEAN CARDIOLOGY 2011 TOUCH BRIEFINGS GBR, VOL. 7, NR. 4, PAGE(S) 280 - 282, (201106), ISSN 1758-3756, XP002717522 [XP] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.15420/ecr.2011.7.4.280
International search[Y]WO2009140452  (UNIV MIAMI [US], et al);
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DOI:   http://dx.doi.org/10.1161/01.cir.0000089186.09692.fa
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DOI:   http://dx.doi.org/10.1093/eurheartj/ehp265
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