EP2621926 - PYRAZOLOPYRIMIDINE PDE10 INHIBITORS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 06.07.2018 Database last updated on 21.05.2024 | |
Former | The patent has been granted Status updated on 28.07.2017 | ||
Former | Grant of patent is intended Status updated on 12.03.2017 | Most recent event Tooltip | 10.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 12.08.2020 [2020/33] | Applicant(s) | For all designated states Merck Sharp & Dohme Corp. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | [2013/32] | Inventor(s) | 01 /
COX, Christopher D. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US | 02 /
RAHEEM, Izzat T. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US | 03 /
SCHREIER, John D. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US | [2017/35] |
Former [2013/32] | 01 /
COX, Christopher, D. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US | ||
02 /
RAHEEM, Izzat, T. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US | |||
03 /
SCHREIER, John, D. 770 Sumneytown Pike West Point, Pennsylvania 19486 / US | Representative(s) | Jaap, David Robert, et al Merck Sharp & Dohme Corp. 120 Moorgate London, EC2M 6UR / GB | [N/P] |
Former [2017/35] | Jaap, David Robert, et al Merck Sharp & Dohme Corp. European Patent Department Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB | ||
Former [2013/32] | Buchan, Gavin MacNicol, et al Merck Sharp & Dohme Limited European Patent Department Hertford Road Hoddesdon Hertfordshire EN11 9BU / GB | Application number, filing date | 11829779.5 | 26.09.2011 | [2017/35] | WO2011US53195 | Priority number, date | US201161497999P | 17.06.2011 Original published format: US 201161497999 P | US20100388298P | 30.09.2010 Original published format: US 388298 P | [2013/32] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2012044562 | Date: | 05.04.2012 | Language: | EN | [2012/14] | Type: | A2 Application without search report | No.: | EP2621926 | Date: | 07.08.2013 | Language: | EN | The application published by WIPO in one of the EPO official languages on 05.04.2012 takes the place of the publication of the European patent application. | [2013/32] | Type: | B1 Patent specification | No.: | EP2621926 | Date: | 30.08.2017 | Language: | EN | [2017/35] | Search report(s) | International search report - published on: | US | 28.06.2012 | (Supplementary) European search report - dispatched on: | EP | 08.08.2014 | Classification | IPC: | C07D487/04, A61K31/519, A61P25/00 | [2014/37] | CPC: |
C07D487/04 (EP,US);
A61K31/519 (EP,US);
A61P25/00 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/28 (EP);
C07D519/00 (EP,US)
(-)
|
Former IPC [2013/32] | C07D487/00 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/32] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | PDE10-PYRAZOLPYRIMIDININHIBITOREN | [2013/32] | English: | PYRAZOLOPYRIMIDINE PDE10 INHIBITORS | [2013/32] | French: | INHIBITEURS DE PYRAZOLOPYRIMIDINE PDE10 | [2013/32] | Entry into regional phase | 02.05.2013 | National basic fee paid | 02.05.2013 | Search fee paid | 02.05.2013 | Designation fee(s) paid | 02.05.2013 | Examination fee paid | Examination procedure | 02.05.2013 | Examination requested [2013/32] | 03.03.2015 | Amendment by applicant (claims and/or description) | 25.02.2016 | Despatch of a communication from the examining division (Time limit: M04) | 06.07.2016 | Reply to a communication from the examining division | 13.03.2017 | Communication of intention to grant the patent | 13.07.2017 | Fee for grant paid | 13.07.2017 | Fee for publishing/printing paid | 13.07.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 25.02.2016 | Opposition(s) | 31.05.2018 | No opposition filed within time limit [2018/32] | Fees paid | Renewal fee | 09.09.2013 | Renewal fee patent year 03 | 08.09.2014 | Renewal fee patent year 04 | 08.09.2015 | Renewal fee patent year 05 | 08.09.2016 | Renewal fee patent year 06 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 26.09.2011 | AL | 30.08.2017 | AT | 30.08.2017 | CY | 30.08.2017 | CZ | 30.08.2017 | DK | 30.08.2017 | EE | 30.08.2017 | ES | 30.08.2017 | FI | 30.08.2017 | HR | 30.08.2017 | IT | 30.08.2017 | LT | 30.08.2017 | LV | 30.08.2017 | MC | 30.08.2017 | MK | 30.08.2017 | NL | 30.08.2017 | PL | 30.08.2017 | PT | 30.08.2017 | RO | 30.08.2017 | RS | 30.08.2017 | SE | 30.08.2017 | SI | 30.08.2017 | SK | 30.08.2017 | SM | 30.08.2017 | TR | 30.08.2017 | IE | 26.09.2017 | LU | 26.09.2017 | MT | 26.09.2017 | BE | 30.09.2017 | CH | 30.09.2017 | LI | 30.09.2017 | BG | 30.11.2017 | NO | 30.11.2017 | GR | 01.12.2017 | IS | 30.12.2017 | [2020/33] |
Former [2020/27] | HU | 26.09.2011 | |
AT | 30.08.2017 | ||
CY | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
MK | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
PT | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
TR | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
MT | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2020/16] | HU | 26.09.2011 | |
AT | 30.08.2017 | ||
CY | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
MK | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
TR | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
MT | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2019/51] | HU | 26.09.2011 | |
AT | 30.08.2017 | ||
CY | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
MK | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
MT | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2019/46] | HU | 26.09.2011 | |
AT | 30.08.2017 | ||
CY | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
MT | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2019/31] | HU | 26.09.2011 | |
AT | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
MT | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/43] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
MT | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/39] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/34] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
IE | 26.09.2017 | ||
LU | 26.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/26] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/24] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/23] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SK | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/21] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/15] | AT | 30.08.2017 | |
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/12] | AT | 30.08.2017 | |
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/11] | AT | 30.08.2017 | |
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/10] | AT | 30.08.2017 | |
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
NO | 30.11.2017 | ||
Former [2018/09] | FI | 30.08.2017 | |
LT | 30.08.2017 | ||
SE | 30.08.2017 | ||
NO | 30.11.2017 | ||
Former [2018/08] | FI | 30.08.2017 | |
LT | 30.08.2017 | ||
NO | 30.11.2017 | ||
Former [2018/07] | LT | 30.08.2017 | |
NO | 30.11.2017 | Documents cited: | Search | [A]US5250534 (BELL ANDREW S [US], et al) [A] 1-14 * See claim 1 * | [A] - Robert H Springer ET AL, "Synthesis and Enzymic Activity of 6-Carbethoxy-and 6-Et hoxy-3,7-disubstit uted-pyrazolo[ 1,5-a ]pyrimidines and Related Derivatives as Adenosine Cyclic 3',5'-Phosphate Phosphodiesterase Inhibitors", J. Med. Chem, (19820101), pages 235 - 242, URL: http://pubs.acs.org/doi/pdf/10.1021/jm00345a009, (20140129), XP055099034 [A] 1-14 * See, e.g. table III, page 238 * | International search | [Y]US2004209878 (GUZI TIMOTHY J [US], et al); | [Y]US2010010017 (LIU RUIPING [US], et al); | [Y]WO2010006130 (ENVIVO PHARMACEUTICALS INC [US], et al) | Examination | WO03014115 | by applicant | US2006041131 | - LIEBERMAN ET AL., N. ENGL. J. MED., (2005), vol. 353, pages 1209 - 1223 | - HUANG, W. ET AL., J. BIOMOL SCREEN, (2002), vol. 7, page 215 | - SIUCIAK ET AL., NEUROPHARMACOLOGY, (2006), vol. 51, pages 386 - 396 | - BECKER ET AL., BEHAV BRAIN RES, (2008), vol. 186, no. 2, pages 155 - 60 | - THRELFELL ET AL., J PHARMACOL EXP THER, (2009), vol. 328, no. 3, pages 785 - 795 | - SCHMIDT ET AL., J PHARMACOL EXP THER, (2008), vol. 325, pages 681 - 690 | - MOSSER ET AL., JALA, (2003), vol. 8, pages 54 - 63 | - FAKHFAKH, M.A.; FRANCK, X.; FOURNET, A.; HOCQUEMILLER, R.; FIGADERE, B., TETRAHEDRON LETT., (2001), vol. 42, page 3847 |