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Extract from the Register of European Patents

EP About this file: EP2632449

EP2632449 - TREATMENT OF OCULAR AND CEREBRAL ISCHEMIA [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.06.2017
Database last updated on 02.09.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Langham Ocular And Cerebral Therapies, LLC
13801 York Road Unit W6
Cockeysville, Maryland 21030 / US
[2013/36]
Inventor(s)01 / LANGHAM, Maurice E.
13801 York Road Unit W6
Cockeysville, Maryland 21030 / US
 [2013/36]
Representative(s)Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[N/P]
Former [2016/34]Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Radlkoferstrasse 2
81373 München / DE
Former [2013/36]Schnappauf, Georg, et al
Dr. Volker Vossius
Patentanwälte / Partnerschaftsgesellschaft
Radlkoferstrasse 2
81373 München / DE
Application number, filing date11838343.925.10.2011
[2016/34]
WO2011US01807
Priority number, dateUS2010092556125.10.2010         Original published format: US 925561
[2013/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012060860
Date:10.05.2012
Language:EN
[2012/19]
Type: A1 Application with search report 
No.:EP2632449
Date:04.09.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 10.05.2012 takes the place of the publication of the European patent application.
[2013/36]
Type: B1 Patent specification 
No.:EP2632449
Date:24.08.2016
Language:EN
[2016/34]
Search report(s)International search report - published on:US10.05.2012
(Supplementary) European search report - dispatched on:EP24.03.2014
ClassificationIPC:A61K31/137, // A61P27/06
[2016/11]
CPC:
A61K31/135 (EP,US); A61K9/0048 (EP,US); A61P27/02 (EP);
A61P27/06 (EP); A61P7/00 (EP)
Former IPC [2016/08]A61K31/137, A61P27/06
Former IPC [2014/16]A61K31/137, // A61P27/06
Former IPC [2013/36]A61K31/135
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/36]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:BEHANDLUNG VON OKULARER UND ZEREBRALER ISCHÄMIE[2013/36]
English:TREATMENT OF OCULAR AND CEREBRAL ISCHEMIA[2013/36]
French:TRAITEMENT D'UNE ISCHÉMIE OCULAIRE ET CÉRÉBRALE[2013/36]
Entry into regional phase27.05.2013National basic fee paid 
27.05.2013Search fee paid 
27.05.2013Designation fee(s) paid 
27.05.2013Examination fee paid 
Examination procedure27.05.2013Examination requested  [2013/36]
15.10.2014Amendment by applicant (claims and/or description)
21.01.2015Despatch of a communication from the examining division (Time limit: M06)
29.07.2015Reply to a communication from the examining division
12.10.2015Despatch of a communication from the examining division (Time limit: M02)
15.12.2015Reply to a communication from the examining division
25.01.2016Communication of intention to grant the patent
03.03.2016Communication of intention to grant the patent
12.07.2016Fee for grant paid
12.07.2016Fee for publishing/printing paid
12.07.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.01.2015
Opposition(s)26.05.2017No opposition filed within time limit [2017/31]
Fees paidRenewal fee
29.10.2013Renewal fee patent year 03
30.10.2014Renewal fee patent year 04
30.10.2015Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.10.2011
AL24.08.2016
AT24.08.2016
CY24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IS24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SI24.08.2016
SK24.08.2016
SM24.08.2016
TR24.08.2016
LU25.10.2016
MT31.10.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
[2018/46]
Former [2018/45]HU25.10.2011
AT24.08.2016
CY24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IS24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SI24.08.2016
SK24.08.2016
SM24.08.2016
TR24.08.2016
LU25.10.2016
MT31.10.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2018/31]HU25.10.2011
AT24.08.2016
CY24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IS24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SI24.08.2016
SK24.08.2016
SM24.08.2016
LU25.10.2016
MT31.10.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2018/28]HU25.10.2011
AT24.08.2016
CY24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SI24.08.2016
SK24.08.2016
SM24.08.2016
LU25.10.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/45]AT24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SI24.08.2016
SK24.08.2016
SM24.08.2016
LU25.10.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/37]AT24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SI24.08.2016
SK24.08.2016
SM24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/32]AT24.08.2016
CZ24.08.2016
EE24.08.2016
FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
NL24.08.2016
PL24.08.2016
RO24.08.2016
RS24.08.2016
SK24.08.2016
SM24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/13]AT24.08.2016
FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
LV24.08.2016
NL24.08.2016
RS24.08.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/11]AT24.08.2016
FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
NL24.08.2016
RS24.08.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/10]FI24.08.2016
HR24.08.2016
IT24.08.2016
LT24.08.2016
NL24.08.2016
RS24.08.2016
NO24.11.2016
Former [2017/09]FI24.08.2016
IT24.08.2016
LT24.08.2016
NL24.08.2016
NO24.11.2016
Former [2017/07]LT24.08.2016
Documents cited:Search[X]WO0178709  (MINERVA BIOTECHNOLOGIES CORP [US]) [X] 3,6,8 * page 35, lines 27-29; claims 7, 113 * * page 8, line 15 *;
 [A]  - WILLIS SENSENBACH ET AL, "A COMPARISON OF THE EFFECTS OF l-NOR-EPINEPHRINE, SYNTHETIC l-EPINEPHRINE, AND U.S.P. EPINEPHRINE UPON CEREBRAL BLOOD FLOW AND METABOLISM IN MAN 1", JOURNAL OF CLINICAL INVESTIGATION, (19530301), vol. 32, no. 3, doi:10.1172/JCI102731, ISSN 0021-9738, pages 226 - 232, XP055106198 [A] 1-8 * See "Discussion";; table 1 *

DOI:   http://dx.doi.org/10.1172/JCI102731
 [A]  - ALM A, "THE EFFECT OF TOPICAL LEVO EPINEPHRINE ON REGIONAL OCULAR BLOOD FLOW IN MONKEYS", INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE, (1980), vol. 19, no. 5, ISSN 0146-0404, pages 487 - 491, XP002721387 [A] 1-8 * table 1 *
International search[Y]US4590210  (LANGHAM MAURICE E [US]);
 [Y]US6403590  (HELLBERG MARK R [US], et al);
 [Y]  - IADECOLA C., "The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia", ACTA NEUROPATHOL., (201009), vol. 120, no. 3, pages 287 - 296, XP019847033
Examination   - LANGHAM MAURICE E ET AL, "The prevention of visual loss by ocular hypotensive drugs", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - IOVS, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, (19950519), vol. 36, no. 4, ISSN 0146-0404, page S966, XP009181772
by applicantUS4590210
 WO0178709
 US3149035
    - DE LA TORRE J.C.; STEFANO, "Evidence that Alzheimer's Disease is a Microvascular Disorder: The Role of Constitutive Nitric Oxide", BRAIN RES. REV., (2000), vol. 34, no. 3, pages 119 - 136
    - SENSENBACH ET AL., J. CLIN. INVEST., (1953), vol. 32, pages 226 - 232
    - ALM, INVEST. OPHTHALMOL. VIS. SCI., (1980), vol. 19, pages 487 - 491
    - LANGHAM ET AL., INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE, (1995), vol. 36, page S966
    - KETY S.S., "Physiopathology of Cerebral Circulation in Vascular Diseases of the Brain", ACTA V. CONGRES NEUROL-INTERNAT. LISBOA, (1953), vol. 1, pages 343 - 351
    - Merck Index, (1976), page 97
    - LANGHAM, M.E.; FARRELL, R.A.; O'BRIEN V.; SILVER, D.M., Non-Invasive Measurement of Pulscztile Ocular Blood Flow in the Human Eye, pages 93 - 99
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.