EP2632449 - TREATMENT OF OCULAR AND CEREBRAL ISCHEMIA [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 30.06.2017 Database last updated on 02.09.2024 | Most recent event Tooltip | 12.10.2018 | Lapse of the patent in a contracting state New state(s): AL | published on 14.11.2018 [2018/46] | Applicant(s) | For all designated states Langham Ocular And Cerebral Therapies, LLC 13801 York Road Unit W6 Cockeysville, Maryland 21030 / US | [2013/36] | Inventor(s) | 01 /
LANGHAM, Maurice E. 13801 York Road Unit W6 Cockeysville, Maryland 21030 / US | [2013/36] | Representative(s) | Schnappauf, Georg, et al ZSP Patentanwälte PartG mbB Hansastraße 32 80686 München / DE | [N/P] |
Former [2016/34] | Schnappauf, Georg, et al ZSP Patentanwälte PartG mbB Radlkoferstrasse 2 81373 München / DE | ||
Former [2013/36] | Schnappauf, Georg, et al Dr. Volker Vossius Patentanwälte / Partnerschaftsgesellschaft Radlkoferstrasse 2 81373 München / DE | Application number, filing date | 11838343.9 | 25.10.2011 | [2016/34] | WO2011US01807 | Priority number, date | US20100925561 | 25.10.2010 Original published format: US 925561 | [2013/36] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2012060860 | Date: | 10.05.2012 | Language: | EN | [2012/19] | Type: | A1 Application with search report | No.: | EP2632449 | Date: | 04.09.2013 | Language: | EN | The application published by WIPO in one of the EPO official languages on 10.05.2012 takes the place of the publication of the European patent application. | [2013/36] | Type: | B1 Patent specification | No.: | EP2632449 | Date: | 24.08.2016 | Language: | EN | [2016/34] | Search report(s) | International search report - published on: | US | 10.05.2012 | (Supplementary) European search report - dispatched on: | EP | 24.03.2014 | Classification | IPC: | A61K31/137, // A61P27/06 | [2016/11] | CPC: |
A61K31/135 (EP,US);
A61K9/0048 (EP,US);
A61P27/02 (EP);
A61P27/06 (EP);
A61P7/00 (EP)
|
Former IPC [2016/08] | A61K31/137, A61P27/06 | ||
Former IPC [2014/16] | A61K31/137, // A61P27/06 | ||
Former IPC [2013/36] | A61K31/135 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/36] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | BEHANDLUNG VON OKULARER UND ZEREBRALER ISCHÄMIE | [2013/36] | English: | TREATMENT OF OCULAR AND CEREBRAL ISCHEMIA | [2013/36] | French: | TRAITEMENT D'UNE ISCHÉMIE OCULAIRE ET CÉRÉBRALE | [2013/36] | Entry into regional phase | 27.05.2013 | National basic fee paid | 27.05.2013 | Search fee paid | 27.05.2013 | Designation fee(s) paid | 27.05.2013 | Examination fee paid | Examination procedure | 27.05.2013 | Examination requested [2013/36] | 15.10.2014 | Amendment by applicant (claims and/or description) | 21.01.2015 | Despatch of a communication from the examining division (Time limit: M06) | 29.07.2015 | Reply to a communication from the examining division | 12.10.2015 | Despatch of a communication from the examining division (Time limit: M02) | 15.12.2015 | Reply to a communication from the examining division | 25.01.2016 | Communication of intention to grant the patent | 03.03.2016 | Communication of intention to grant the patent | 12.07.2016 | Fee for grant paid | 12.07.2016 | Fee for publishing/printing paid | 12.07.2016 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 21.01.2015 | Opposition(s) | 26.05.2017 | No opposition filed within time limit [2017/31] | Fees paid | Renewal fee | 29.10.2013 | Renewal fee patent year 03 | 30.10.2014 | Renewal fee patent year 04 | 30.10.2015 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 25.10.2011 | AL | 24.08.2016 | AT | 24.08.2016 | CY | 24.08.2016 | CZ | 24.08.2016 | EE | 24.08.2016 | FI | 24.08.2016 | HR | 24.08.2016 | IS | 24.08.2016 | IT | 24.08.2016 | LT | 24.08.2016 | LV | 24.08.2016 | MC | 24.08.2016 | MK | 24.08.2016 | NL | 24.08.2016 | PL | 24.08.2016 | RO | 24.08.2016 | RS | 24.08.2016 | SI | 24.08.2016 | SK | 24.08.2016 | SM | 24.08.2016 | TR | 24.08.2016 | LU | 25.10.2016 | MT | 31.10.2016 | BG | 24.11.2016 | NO | 24.11.2016 | GR | 25.11.2016 | PT | 26.12.2016 | [2018/46] |
Former [2018/45] | HU | 25.10.2011 | |
AT | 24.08.2016 | ||
CY | 24.08.2016 | ||
CZ | 24.08.2016 | ||
EE | 24.08.2016 | ||
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IS | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
LV | 24.08.2016 | ||
MC | 24.08.2016 | ||
MK | 24.08.2016 | ||
NL | 24.08.2016 | ||
PL | 24.08.2016 | ||
RO | 24.08.2016 | ||
RS | 24.08.2016 | ||
SI | 24.08.2016 | ||
SK | 24.08.2016 | ||
SM | 24.08.2016 | ||
TR | 24.08.2016 | ||
LU | 25.10.2016 | ||
MT | 31.10.2016 | ||
BG | 24.11.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2018/31] | HU | 25.10.2011 | |
AT | 24.08.2016 | ||
CY | 24.08.2016 | ||
CZ | 24.08.2016 | ||
EE | 24.08.2016 | ||
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IS | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
LV | 24.08.2016 | ||
MC | 24.08.2016 | ||
MK | 24.08.2016 | ||
NL | 24.08.2016 | ||
PL | 24.08.2016 | ||
RO | 24.08.2016 | ||
RS | 24.08.2016 | ||
SI | 24.08.2016 | ||
SK | 24.08.2016 | ||
SM | 24.08.2016 | ||
LU | 25.10.2016 | ||
MT | 31.10.2016 | ||
BG | 24.11.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2018/28] | HU | 25.10.2011 | |
AT | 24.08.2016 | ||
CY | 24.08.2016 | ||
CZ | 24.08.2016 | ||
EE | 24.08.2016 | ||
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
LV | 24.08.2016 | ||
MC | 24.08.2016 | ||
MK | 24.08.2016 | ||
NL | 24.08.2016 | ||
PL | 24.08.2016 | ||
RO | 24.08.2016 | ||
RS | 24.08.2016 | ||
SI | 24.08.2016 | ||
SK | 24.08.2016 | ||
SM | 24.08.2016 | ||
LU | 25.10.2016 | ||
BG | 24.11.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2017/45] | AT | 24.08.2016 | |
CZ | 24.08.2016 | ||
EE | 24.08.2016 | ||
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
LV | 24.08.2016 | ||
NL | 24.08.2016 | ||
PL | 24.08.2016 | ||
RO | 24.08.2016 | ||
RS | 24.08.2016 | ||
SI | 24.08.2016 | ||
SK | 24.08.2016 | ||
SM | 24.08.2016 | ||
LU | 25.10.2016 | ||
BG | 24.11.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2017/37] | AT | 24.08.2016 | |
CZ | 24.08.2016 | ||
EE | 24.08.2016 | ||
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
LV | 24.08.2016 | ||
NL | 24.08.2016 | ||
PL | 24.08.2016 | ||
RO | 24.08.2016 | ||
RS | 24.08.2016 | ||
SI | 24.08.2016 | ||
SK | 24.08.2016 | ||
SM | 24.08.2016 | ||
BG | 24.11.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2017/32] | AT | 24.08.2016 | |
CZ | 24.08.2016 | ||
EE | 24.08.2016 | ||
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
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PL | 24.08.2016 | ||
RO | 24.08.2016 | ||
RS | 24.08.2016 | ||
SK | 24.08.2016 | ||
SM | 24.08.2016 | ||
BG | 24.11.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2017/13] | AT | 24.08.2016 | |
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
LV | 24.08.2016 | ||
NL | 24.08.2016 | ||
RS | 24.08.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2017/11] | AT | 24.08.2016 | |
FI | 24.08.2016 | ||
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
NL | 24.08.2016 | ||
RS | 24.08.2016 | ||
NO | 24.11.2016 | ||
GR | 25.11.2016 | ||
PT | 26.12.2016 | ||
Former [2017/10] | FI | 24.08.2016 | |
HR | 24.08.2016 | ||
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
NL | 24.08.2016 | ||
RS | 24.08.2016 | ||
NO | 24.11.2016 | ||
Former [2017/09] | FI | 24.08.2016 | |
IT | 24.08.2016 | ||
LT | 24.08.2016 | ||
NL | 24.08.2016 | ||
NO | 24.11.2016 | ||
Former [2017/07] | LT | 24.08.2016 | Documents cited: | Search | [X]WO0178709 (MINERVA BIOTECHNOLOGIES CORP [US]) [X] 3,6,8 * page 35, lines 27-29; claims 7, 113 * * page 8, line 15 *; | [A] - WILLIS SENSENBACH ET AL, "A COMPARISON OF THE EFFECTS OF l-NOR-EPINEPHRINE, SYNTHETIC l-EPINEPHRINE, AND U.S.P. EPINEPHRINE UPON CEREBRAL BLOOD FLOW AND METABOLISM IN MAN 1", JOURNAL OF CLINICAL INVESTIGATION, (19530301), vol. 32, no. 3, doi:10.1172/JCI102731, ISSN 0021-9738, pages 226 - 232, XP055106198 [A] 1-8 * See "Discussion";; table 1 * DOI: http://dx.doi.org/10.1172/JCI102731 | [A] - ALM A, "THE EFFECT OF TOPICAL LEVO EPINEPHRINE ON REGIONAL OCULAR BLOOD FLOW IN MONKEYS", INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE, (1980), vol. 19, no. 5, ISSN 0146-0404, pages 487 - 491, XP002721387 [A] 1-8 * table 1 * | International search | [Y]US4590210 (LANGHAM MAURICE E [US]); | [Y]US6403590 (HELLBERG MARK R [US], et al); | [Y] - IADECOLA C., "The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia", ACTA NEUROPATHOL., (201009), vol. 120, no. 3, pages 287 - 296, XP019847033 | Examination | - LANGHAM MAURICE E ET AL, "The prevention of visual loss by ocular hypotensive drugs", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - IOVS, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, (19950519), vol. 36, no. 4, ISSN 0146-0404, page S966, XP009181772 | by applicant | US4590210 | WO0178709 | US3149035 | - DE LA TORRE J.C.; STEFANO, "Evidence that Alzheimer's Disease is a Microvascular Disorder: The Role of Constitutive Nitric Oxide", BRAIN RES. REV., (2000), vol. 34, no. 3, pages 119 - 136 | - SENSENBACH ET AL., J. CLIN. INVEST., (1953), vol. 32, pages 226 - 232 | - ALM, INVEST. OPHTHALMOL. VIS. SCI., (1980), vol. 19, pages 487 - 491 | - LANGHAM ET AL., INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE, (1995), vol. 36, page S966 | - KETY S.S., "Physiopathology of Cerebral Circulation in Vascular Diseases of the Brain", ACTA V. CONGRES NEUROL-INTERNAT. LISBOA, (1953), vol. 1, pages 343 - 351 | - Merck Index, (1976), page 97 | - LANGHAM, M.E.; FARRELL, R.A.; O'BRIEN V.; SILVER, D.M., Non-Invasive Measurement of Pulscztile Ocular Blood Flow in the Human Eye, pages 93 - 99 |