EP2646441 - CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 07.10.2016 Database last updated on 19.10.2024 | Most recent event Tooltip | 12.10.2018 | Lapse of the patent in a contracting state New state(s): AL | published on 14.11.2018 [2018/46] | Applicant(s) | For all designated states Epizyme, Inc. 400 Technology Square, 4th Floor Cambridge, MA 02139 / US | [2015/49] |
Former [2013/41] | For all designated states Epizyme, Inc. 400 Technology Square, 4th Floor Cambridge, MA 02139 / US | Inventor(s) | 01 /
OLHAVA, Edward James 11 Scarsdale Road Newton MA 02460 / US | 02 /
CHESWORTH, Richard 584 Strawberry Hill Road Concord MA 01742 / US | 03 /
KUNTZ, Kevin, Wayne 8 New Village Road Woburn MA 01801 / US | [2013/41] | Representative(s) | Harris, Jennifer Lucy, et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL / GB | [N/P] |
Former [2015/49] | Harris, Jennifer Lucy, et al Kilburn & Strode LLP 20 Red Lion Street London WC1R 4PJ / GB | ||
Former [2013/41] | Mintz Levin Cohn Ferris Glovsky and Popeo LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | Application number, filing date | 11845232.5 | 05.12.2011 | [2015/49] | WO2011US63289 | Priority number, date | US20100419668P | 03.12.2010 Original published format: US 419668 P | [2013/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2012075492 | Date: | 07.06.2012 | Language: | EN | [2012/23] | Type: | A2 Application without search report | No.: | EP2646441 | Date: | 09.10.2013 | Language: | EN | The application published by WIPO in one of the EPO official languages on 07.06.2012 takes the place of the publication of the European patent application. | [2013/41] | Type: | B1 Patent specification | No.: | EP2646441 | Date: | 02.12.2015 | Language: | EN | [2015/49] | Search report(s) | International search report - published on: | KR | 26.07.2012 | (Supplementary) European search report - dispatched on: | EP | 09.04.2014 | Classification | IPC: | C07D473/34, C07D487/04, A61K31/519, A61K31/52, A61P35/00, A61P25/00 | [2014/19] | CPC: |
C07D487/04 (EP,US);
A61P25/00 (EP);
A61P35/00 (EP);
C07D473/34 (EP,US)
|
Former IPC [2013/41] | C07D471/04, C07D401/12, C07D235/14, A61K31/52, A61P35/00, A61P25/00 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/41] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | CARBOCYCLUS-SUBSTITUIERTE PURIN- UND 7-DEAZAPURIN-VERBINDUNGEN | [2013/41] | English: | CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS | [2013/41] | French: | PURINE SUBSTITUÉE PAR UN CARBOCYCLE ET COMPOSÉS DE 7-DÉAZAPURINE | [2013/41] | Entry into regional phase | 02.07.2013 | National basic fee paid | 02.07.2013 | Search fee paid | 02.07.2013 | Designation fee(s) paid | 02.07.2013 | Examination fee paid | Examination procedure | 02.07.2013 | Examination requested [2013/41] | 28.10.2014 | Amendment by applicant (claims and/or description) | 19.06.2015 | Communication of intention to grant the patent | 14.10.2015 | Fee for grant paid | 14.10.2015 | Fee for publishing/printing paid | 14.10.2015 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 19.06.2015 | Opposition(s) | 05.09.2016 | No opposition filed within time limit [2016/45] | Fees paid | Renewal fee | 27.12.2013 | Renewal fee patent year 03 | 05.12.2014 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 05.12.2011 | AL | 02.12.2015 | AT | 02.12.2015 | BE | 02.12.2015 | BG | 02.12.2015 | CY | 02.12.2015 | CZ | 02.12.2015 | DK | 02.12.2015 | EE | 02.12.2015 | ES | 02.12.2015 | FI | 02.12.2015 | HR | 02.12.2015 | IT | 02.12.2015 | LT | 02.12.2015 | LV | 02.12.2015 | MC | 02.12.2015 | MK | 02.12.2015 | MT | 02.12.2015 | NL | 02.12.2015 | PL | 02.12.2015 | RO | 02.12.2015 | RS | 02.12.2015 | SE | 02.12.2015 | SI | 02.12.2015 | SK | 02.12.2015 | SM | 02.12.2015 | TR | 02.12.2015 | IE | 05.12.2015 | LU | 05.12.2015 | CH | 31.12.2015 | LI | 31.12.2015 | NO | 02.03.2016 | GR | 03.03.2016 | IS | 02.04.2016 | PT | 04.04.2016 | [2018/46] |
Former [2018/31] | HU | 05.12.2011 | |
AT | 02.12.2015 | ||
BE | 02.12.2015 | ||
BG | 02.12.2015 | ||
CY | 02.12.2015 | ||
CZ | 02.12.2015 | ||
DK | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
HR | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
MK | 02.12.2015 | ||
MT | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SI | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
TR | 02.12.2015 | ||
IE | 05.12.2015 | ||
LU | 05.12.2015 | ||
CH | 31.12.2015 | ||
LI | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2018/02] | HU | 05.12.2011 | |
AT | 02.12.2015 | ||
BE | 02.12.2015 | ||
BG | 02.12.2015 | ||
CY | 02.12.2015 | ||
CZ | 02.12.2015 | ||
DK | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
HR | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
MT | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SI | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
IE | 05.12.2015 | ||
LU | 05.12.2015 | ||
CH | 31.12.2015 | ||
LI | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2017/39] | HU | 05.12.2011 | |
AT | 02.12.2015 | ||
BE | 02.12.2015 | ||
BG | 02.12.2015 | ||
CY | 02.12.2015 | ||
CZ | 02.12.2015 | ||
DK | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
HR | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
MT | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SI | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
IE | 05.12.2015 | ||
CH | 31.12.2015 | ||
LI | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2017/03] | AT | 02.12.2015 | |
BE | 02.12.2015 | ||
CZ | 02.12.2015 | ||
DK | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SI | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
IE | 05.12.2015 | ||
CH | 31.12.2015 | ||
LI | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2016/49] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
DK | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SI | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
IE | 05.12.2015 | ||
BE | 31.12.2015 | ||
CH | 31.12.2015 | ||
LI | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2016/46] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
DK | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
IE | 05.12.2015 | ||
BE | 31.12.2015 | ||
CH | 31.12.2015 | ||
LI | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2016/45] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
IE | 05.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2016/42] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
MC | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2016/38] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SK | 02.12.2015 | ||
SM | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
IS | 02.04.2016 | ||
PT | 04.04.2016 | ||
Former [2016/36] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
EE | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IS | 02.12.2015 | ||
IT | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RO | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
SK | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
Former [2016/34] | AT | 02.12.2015 | |
CZ | 02.12.2015 | ||
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IS | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
Former [2016/31] | AT | 02.12.2015 | |
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
IS | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
Former [2016/26] | AT | 02.12.2015 | |
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
NL | 02.12.2015 | ||
PL | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
Former [2016/25] | AT | 02.12.2015 | |
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
LT | 02.12.2015 | ||
LV | 02.12.2015 | ||
PL | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
Former [2016/24] | AT | 02.12.2015 | |
ES | 02.12.2015 | ||
FI | 02.12.2015 | ||
LT | 02.12.2015 | ||
PL | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
BE | 31.12.2015 | ||
NO | 02.03.2016 | ||
GR | 03.03.2016 | ||
Former [2016/23] | ES | 02.12.2015 | |
LT | 02.12.2015 | ||
RS | 02.12.2015 | ||
SE | 02.12.2015 | ||
NO | 02.03.2016 | ||
Former [2016/21] | ES | 02.12.2015 | |
LT | 02.12.2015 | ||
NO | 02.03.2016 | ||
Former [2016/20] | ES | 02.12.2015 | |
LT | 02.12.2015 | Documents cited: | Search | [A]WO2004022572 (ALCHEMIA PTY LTD [AU], et al) [A] 1-15 * the whole document; in particular, claims 1 and 13 *; | [A]US4794174 (SECRIST III JOHN A [US]) [A] 1-15 * the whole document *; | [A] - COLE, PHILIP A., "Chemical probes for histone -modifying enzymes", NATURE CHEMICAL BIOLOGY, CODEN: NCBABT; ISSN: 1552-4450, (200810), vol. 4, no. 10, doi:10.1038/NCHEMBIO.111, pages 590 - 597, XP002721783 [A] 1-15 * the whole document; in particular, Figure 2 and Figure 6 * DOI: http://dx.doi.org/10.1038/NCHEMBIO.111 | International search | [A]US2007191293 (LANGSTON STEVEN P [US], et al); | [A]US2009105476 (FAIRHURST ROBIN ALEC [GB], et al); | [A]EP2208721 (ZHEJIANG HISUN PHARMACEUTICAL [CN], et al) |