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Extract from the Register of European Patents

EP About this file: EP2646441

EP2646441 - CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.10.2016
Database last updated on 19.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL
published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Epizyme, Inc.
400 Technology Square, 4th Floor
Cambridge, MA 02139 / US
[2015/49]
Former [2013/41]For all designated states
Epizyme, Inc.
400 Technology Square, 4th Floor
Cambridge, MA 02139 / US
Inventor(s)01 / OLHAVA, Edward James
11 Scarsdale Road
Newton MA 02460 / US
02 / CHESWORTH, Richard
584 Strawberry Hill Road
Concord MA 01742 / US
03 / KUNTZ, Kevin, Wayne
8 New Village Road
Woburn MA 01801 / US
 [2013/41]
Representative(s)Harris, Jennifer Lucy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2015/49]Harris, Jennifer Lucy, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Former [2013/41]Mintz Levin Cohn Ferris Glovsky and Popeo LLP
Alder Castle
10 Noble Street
London EC2V 7JX / GB
Application number, filing date11845232.505.12.2011
[2015/49]
WO2011US63289
Priority number, dateUS20100419668P03.12.2010         Original published format: US 419668 P
[2013/41]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2012075492
Date:07.06.2012
Language:EN
[2012/23]
Type: A2 Application without search report 
No.:EP2646441
Date:09.10.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 07.06.2012 takes the place of the publication of the European patent application.
[2013/41]
Type: B1 Patent specification 
No.:EP2646441
Date:02.12.2015
Language:EN
[2015/49]
Search report(s)International search report - published on:KR26.07.2012
(Supplementary) European search report - dispatched on:EP09.04.2014
ClassificationIPC:C07D473/34, C07D487/04, A61K31/519, A61K31/52, A61P35/00, A61P25/00
[2014/19]
CPC:
C07D487/04 (EP,US); A61P25/00 (EP); A61P35/00 (EP);
C07D473/34 (EP,US)
Former IPC [2013/41]C07D471/04, C07D401/12, C07D235/14, A61K31/52, A61P35/00, A61P25/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/41]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:CARBOCYCLUS-SUBSTITUIERTE PURIN- UND 7-DEAZAPURIN-VERBINDUNGEN[2013/41]
English:CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS[2013/41]
French:PURINE SUBSTITUÉE PAR UN CARBOCYCLE ET COMPOSÉS DE 7-DÉAZAPURINE[2013/41]
Entry into regional phase02.07.2013National basic fee paid 
02.07.2013Search fee paid 
02.07.2013Designation fee(s) paid 
02.07.2013Examination fee paid 
Examination procedure02.07.2013Examination requested  [2013/41]
28.10.2014Amendment by applicant (claims and/or description)
19.06.2015Communication of intention to grant the patent
14.10.2015Fee for grant paid
14.10.2015Fee for publishing/printing paid
14.10.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  19.06.2015
Opposition(s)05.09.2016No opposition filed within time limit [2016/45]
Fees paidRenewal fee
27.12.2013Renewal fee patent year 03
05.12.2014Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU05.12.2011
AL02.12.2015
AT02.12.2015
BE02.12.2015
BG02.12.2015
CY02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
HR02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
MK02.12.2015
MT02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SI02.12.2015
SK02.12.2015
SM02.12.2015
TR02.12.2015
IE05.12.2015
LU05.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
[2018/46]
Former [2018/31]HU05.12.2011
AT02.12.2015
BE02.12.2015
BG02.12.2015
CY02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
HR02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
MK02.12.2015
MT02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SI02.12.2015
SK02.12.2015
SM02.12.2015
TR02.12.2015
IE05.12.2015
LU05.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2018/02]HU05.12.2011
AT02.12.2015
BE02.12.2015
BG02.12.2015
CY02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
HR02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
MT02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SI02.12.2015
SK02.12.2015
SM02.12.2015
IE05.12.2015
LU05.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2017/39]HU05.12.2011
AT02.12.2015
BE02.12.2015
BG02.12.2015
CY02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
HR02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
MT02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SI02.12.2015
SK02.12.2015
SM02.12.2015
IE05.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2017/03]AT02.12.2015
BE02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SI02.12.2015
SK02.12.2015
SM02.12.2015
IE05.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2016/49]AT02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SI02.12.2015
SK02.12.2015
SM02.12.2015
IE05.12.2015
BE31.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2016/46]AT02.12.2015
CZ02.12.2015
DK02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SK02.12.2015
SM02.12.2015
IE05.12.2015
BE31.12.2015
CH31.12.2015
LI31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2016/45]AT02.12.2015
CZ02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SK02.12.2015
SM02.12.2015
IE05.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2016/42]AT02.12.2015
CZ02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
MC02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SK02.12.2015
SM02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2016/38]AT02.12.2015
CZ02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SK02.12.2015
SM02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
IS02.04.2016
PT04.04.2016
Former [2016/36]AT02.12.2015
CZ02.12.2015
EE02.12.2015
ES02.12.2015
FI02.12.2015
IS02.12.2015
IT02.12.2015
LT02.12.2015
LV02.12.2015
NL02.12.2015
PL02.12.2015
RO02.12.2015
RS02.12.2015
SE02.12.2015
SK02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
Former [2016/34]AT02.12.2015
CZ02.12.2015
ES02.12.2015
FI02.12.2015
IS02.12.2015
LT02.12.2015
LV02.12.2015
NL02.12.2015
PL02.12.2015
RS02.12.2015
SE02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
Former [2016/31]AT02.12.2015
ES02.12.2015
FI02.12.2015
IS02.12.2015
LT02.12.2015
LV02.12.2015
NL02.12.2015
PL02.12.2015
RS02.12.2015
SE02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
Former [2016/26]AT02.12.2015
ES02.12.2015
FI02.12.2015
LT02.12.2015
LV02.12.2015
NL02.12.2015
PL02.12.2015
RS02.12.2015
SE02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
Former [2016/25]AT02.12.2015
ES02.12.2015
FI02.12.2015
LT02.12.2015
LV02.12.2015
PL02.12.2015
RS02.12.2015
SE02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
Former [2016/24]AT02.12.2015
ES02.12.2015
FI02.12.2015
LT02.12.2015
PL02.12.2015
RS02.12.2015
SE02.12.2015
BE31.12.2015
NO02.03.2016
GR03.03.2016
Former [2016/23]ES02.12.2015
LT02.12.2015
RS02.12.2015
SE02.12.2015
NO02.03.2016
Former [2016/21]ES02.12.2015
LT02.12.2015
NO02.03.2016
Former [2016/20]ES02.12.2015
LT02.12.2015
Documents cited:Search[A]WO2004022572  (ALCHEMIA PTY LTD [AU], et al) [A] 1-15 * the whole document; in particular, claims 1 and 13 *;
 [A]US4794174  (SECRIST III JOHN A [US]) [A] 1-15 * the whole document *;
 [A]  - COLE, PHILIP A., "Chemical probes for histone -modifying enzymes", NATURE CHEMICAL BIOLOGY, CODEN: NCBABT; ISSN: 1552-4450, (200810), vol. 4, no. 10, doi:10.1038/NCHEMBIO.111, pages 590 - 597, XP002721783 [A] 1-15 * the whole document; in particular, Figure 2 and Figure 6 *

DOI:   http://dx.doi.org/10.1038/NCHEMBIO.111
International search[A]US2007191293  (LANGSTON STEVEN P [US], et al);
 [A]US2009105476  (FAIRHURST ROBIN ALEC [GB], et al);
 [A]EP2208721  (ZHEJIANG HISUN PHARMACEUTICAL [CN], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.