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EP About this file: EP2692731

EP2692731 - Recombinant Adeno-Associated virus (AAV) vector particles displaying high-affinity ligands for cell-type specific gene delivery [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 26.12.2014 Database last updated on 28.09.2024
Most recent event Tooltip	26.12.2014	Application deemed to be withdrawn	published on 28.01.2015 [2015/05]
Applicant(s)	For all designated states Paul-Ehrlich-Institut Bundesamt für Sera und Impfstoffe Paul-Ehrlich-Strasse 51-59 63225 Langen / DE
	For all designated states Universität zu Köln Albertus-Magnus-Platz 50923 Köln / DE
	[2014/06]
Inventor(s)	01 / Bucholz, Christian Schulstrasse 10 60594 Frankfurt / DE
	02 / Münch, Robert Paul-Ehrlich-Strasse 28 60596 Frankfurt / DE
	03 / Büning, Hildegard Aachenerstrasse 590 50933 Köln / DE
	[2014/06]
Representative(s)	Schüssler, Andrea Kanzlei Huber & Schüssler Truderinger Strasse 246 81825 München / DE
	[N/P]
Former [2014/06]	Schüssler, Andrea Kanzlei Huber & Schüssler Truderinger Strasse 246 81825 München / DE
Application number, filing date	12005565.2	31.07.2012
	[2014/06]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP2692731
	Date:	05.02.2014
	Language:	EN
	[2014/06]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	20.12.2013
Classification	IPC:	C07K14/005, A61K48/00, C12N15/86	[2014/06]
	CPC:	A61K48/005 (EP); C07K14/005 (EP); C12N15/86 (EP); C07K2319/74 (EP); C12N2750/14122 (EP); C12N2750/14143 (EP); (+) C12N2750/14145 (EP); C12N2750/14171 (EP); C12N2810/40 (EP) (-)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/06]
Extension states	BA	Not yet paid
	ME	Not yet paid
Title	German:	Rekombinante AAV-Vektorparitikel mit Liganden hoher Affinität für Zelltyp-spezifischen Gentransfer	[2014/06]
	English:	Recombinant Adeno-Associated virus (AAV) vector particles displaying high-affinity ligands for cell-type specific gene delivery	[2014/06]
	French:	Particules de vecteur AAV présentant des ligands à affinité élevée pour l'administration de gènes spécifique du type cellulaire	[2014/06]
Examination procedure	06.08.2014	Application deemed to be withdrawn, date of legal effect [2015/05]
	12.09.2014	Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time [2015/05]
Fees paid	Penalty fee
	Additional fee for renewal fee
	31.07.2014	03 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[Y]WO03054197 (MEDIGENE AG [DE], et al) [Y] 1-12 * the whole document *;
		[Y]WO0220565 (UNIV ZUERICH [CH], et al) [Y] 1-12 * the whole document *;
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		[Y] - NICKLIN S A ET AL, "Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells", MOLECULAR THERAPY, NATURE PUBLISHING GROUP, GB, (20010901), vol. 4, no. 3, doi:10.1006/MTHE.2001.0424, ISSN 1525-0016, pages 174 - 181, XP002297272 [Y] 1-12 * the whole document * DOI: http://dx.doi.org/10.1006/mthe.2001.0424
		[Y] - NI-CHUNG LEE ET AL, "An acidic oligopeptide displayed on AAV2 improves axial muscle tropism after systemic delivery", GENETIC VACCINES AND THERAPY, BIOMED CENTRAL, LONDON, GB, (20120618), vol. 10, no. 1, doi:10.1186/1479-0556-10-3, ISSN 1479-0556, page 3, XP021133105 [Y] 1-12 * the whole document * DOI: http://dx.doi.org/10.1186/1479-0556-10-3
		[Y] - ROBERT C MÜNCH ET AL, "DARPins: An Efficient Targeting Domain for Lentiviral Vectors", MOLECULAR THERAPY, (20110401), vol. 19, no. 4, doi:10.1038/mt.2010.298, ISSN 1525-0016, pages 686 - 693, XP055092878 [Y] 1-12 * the whole document * DOI: http://dx.doi.org/10.1038/mt.2010.298
		[Y] - K FRIEDRICH ET AL., "Effective DARPin-targeted oncolytic measles viruses directed against HER2/neu, EGFR, or EpCAM expressing tumor cells", HUMAN GENE THERAPY, (20111001), vol. 22, no. 10, doi:10.1089/hum.2011.2525, ISSN 1043-0342, page A97, XP055036692 [Y] 1-12 * Poster 261 * DOI: http://dx.doi.org/10.1089/hum.2011.2525
		[Y] - Mikheeva G et al., "Design of Bi-Specific DARPin-Derived Adapters for Targeting of Adenovirus Vectors", (20090530), 12th Annual Meeting of the American Society of Gene Therapy, URL: http://www.asgct.org/am09/final_program.pdf, (20120717), XP055032939 [Y] 1-7,10-12 * Poster 850 *
		[A] - ZAHND ET AL, "A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20070517), vol. 369, no. 4, doi:10.1016/J.JMB.2007.03.028, ISSN 0022-2836, pages 1015 - 1028, XP022083577 [A] 8,9 * the whole document * DOI: http://dx.doi.org/10.1016/j.jmb.2007.03.028
		[A] - ANDREAS SCHWEIZER ET AL, "CD4-Specific Designed Ankyrin Repeat Proteins Are Novel Potent HIV Entry Inhibitors with Unique Characteristics", PLOS PATHOGENS, (20080725), vol. 4, no. 7, doi:10.1371/journal.ppat.1000109, page e1000109, XP055092927 [A] 8,9 * the whole document * DOI: http://dx.doi.org/10.1371/journal.ppat.1000109
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