EP2522671 - Modulators of 5-HT receptors and methods of use thereof [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 25.11.2016 Database last updated on 24.08.2024 | Most recent event Tooltip | 01.05.2020 | Change - lapse in a contracting state | published on 03.06.2020 [2020/23] | Applicant(s) | For all designated states AbbVie Inc. 1 North Waukegan Road North Chicago, IL 60064 / US | For all designated states AbbVie Deutschland GmbH & Co KG Max-Planck-Ring 2a 65205 Wiesbaden / DE | [2013/42] |
Former [2013/24] | For all designated states AbbVie Inc. 1 North Waukegan Road North Chicago, IL 60064 / US | ||
For all designated states Abbott GmbH & Co. KG Max-Planck-Ring 2 65205 Wiesbaden / DE | |||
Former [2012/46] | For all designated states Abbott Laboratories 100 Abbott Park Road Abbott Park, Illinois 60064-6008 / US | ||
For all designated states Abbott GmbH & Co. KG Max-Planck-Ring 2 65205 Wiesbaden / DE | Inventor(s) | 01 /
Wang, Ying 18833 Chatham Way Lake Villa, IL Illinois 60046 / US | 02 /
Brewer, Jason, T. 3901 Harmony Court Zion, IL Illinois 60099 / US | 03 /
Akritopoulou-Zanze, Irini 1817 South Waxwing Lane Libertyville, IL Illinois 60048 / US | 04 /
Djuric, Stevan, W. 621 Paddock Lane Libertyville, IL Illinois 60048 / US | 05 /
Pohlki, Frauke Neustadter Strasse 20 67112 Mutterstadt / DE | 06 /
Braje, Wilfried Emil-Heckel-Str. 4 68163 Mannheim / DE | 07 /
Relo, Ana-Lucia Romerweg 12 67161 Gonnheim / DE | [2012/46] | Representative(s) | Modiano, Micaela Nadia, et al Modiano & Partners (DE) Thierschstrasse 11 80538 München / DE | [2012/46] | Application number, filing date | 12175535.9 | 22.04.2010 | [2012/46] | Priority number, date | US20090171912P | 23.04.2009 Original published format: US 171912 P | [2012/46] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2522671 | Date: | 14.11.2012 | Language: | EN | [2012/46] | Type: | A3 Search report | No.: | EP2522671 | Date: | 24.04.2013 | Language: | EN | [2013/17] | Type: | B1 Patent specification | No.: | EP2522671 | Date: | 20.01.2016 | Language: | EN | [2016/03] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 27.03.2013 | Classification | IPC: | C07D498/04, C07D471/04, C07D471/14, C07D487/04, C07D491/04, // A61K31/4985, A61K31/551, A61K31/553, A61P25/00 | [2012/46] | CPC: |
C07D498/04 (EP,CN);
C07D487/04 (EP,CN);
A61P1/00 (EP);
A61P1/04 (EP);
A61P1/14 (EP);
A61P13/02 (EP);
A61P13/10 (EP);
A61P15/00 (EP);
A61P15/10 (EP);
A61P17/06 (EP);
A61P25/00 (EP);
A61P25/04 (EP);
A61P25/06 (EP);
A61P25/08 (EP);
A61P25/10 (EP);
A61P25/14 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/20 (EP);
A61P25/22 (EP);
A61P25/24 (EP);
A61P25/28 (EP);
A61P25/30 (EP);
A61P25/34 (EP);
A61P25/36 (EP);
A61P27/02 (EP);
A61P27/06 (EP);
A61P3/04 (EP);
A61P3/10 (EP);
A61P43/00 (EP);
A61P7/12 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
C07D471/04 (EP,CN);
C07D471/14 (EP);
C07D487/14 (CN);
C07D491/04 (EP)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2016/03] |
Former [2012/46] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR | Title | German: | 5-HT-Rezeptor-Modulatoren und Verfahren zu ihrer Verwendung | [2012/46] | English: | Modulators of 5-HT receptors and methods of use thereof | [2012/46] | French: | Modulateurs de récepteurs 5-HT et leurs procédés d'utilisation | [2012/46] | Examination procedure | 11.11.2013 | Amendment by applicant (claims and/or description) | 11.11.2013 | Examination requested [2013/51] | 05.12.2013 | Despatch of a communication from the examining division (Time limit: M04) | 15.04.2014 | Reply to a communication from the examining division | 29.09.2014 | Despatch of a communication from the examining division (Time limit: M06) | 08.04.2015 | Reply to a communication from the examining division | 08.07.2015 | Communication of intention to grant the patent | 11.11.2015 | Fee for grant paid | 11.11.2015 | Fee for publishing/printing paid | 11.11.2015 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP10716195.2 / EP2421870 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20100716195) is 11.04.2014 | Opposition(s) | 21.10.2016 | No opposition filed within time limit [2016/52] | Request for further processing for: | The application is deemed to be withdrawn due to non-payment of designation fees PT, EE, TR, SM, SK, SI, SE, RO, PL, NO, NL, MT, MK, MC, LV, LU, LT, IT, IS, IE, HU, HR, GR, GB, FR, FI, ES, DK, DE, CZ, CY, CH, BG, BE, AT | 11.11.2013 | Request for further processing filed | 11.11.2013 | Full payment received (date of receipt of payment) Request granted | 22.11.2013 | Decision despatched | The application is deemed to be withdrawn due to non-payment of the examination fee | 11.11.2013 | Request for further processing filed | 11.11.2013 | Full payment received (date of receipt of payment) Request granted | 22.11.2013 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 11.11.2013 | Request for further processing filed | 11.11.2013 | Full payment received (date of receipt of payment) Request granted | 22.11.2013 | Decision despatched | Fees paid | Renewal fee | 09.07.2012 | Renewal fee patent year 03 | 26.03.2013 | Renewal fee patent year 04 | 26.03.2014 | Renewal fee patent year 05 | 08.04.2015 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 22.04.2010 | AT | 20.01.2016 | BE | 20.01.2016 | CY | 20.01.2016 | CZ | 20.01.2016 | DK | 20.01.2016 | EE | 20.01.2016 | FI | 20.01.2016 | HR | 20.01.2016 | LT | 20.01.2016 | LV | 20.01.2016 | MC | 20.01.2016 | MK | 20.01.2016 | NL | 20.01.2016 | PL | 20.01.2016 | RO | 20.01.2016 | SE | 20.01.2016 | SI | 20.01.2016 | SK | 20.01.2016 | SM | 20.01.2016 | TR | 20.01.2016 | BG | 20.04.2016 | NO | 20.04.2016 | GR | 21.04.2016 | IE | 22.04.2016 | LU | 22.04.2016 | CH | 30.04.2016 | LI | 30.04.2016 | MT | 30.04.2016 | IS | 20.05.2016 | PT | 20.05.2016 | [2020/23] |
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Former [2016/30] | NL | 20.01.2016 | Documents cited: | Search | [XP]WO2009098236 (NOVARTIS AG [CH], et al) [XP] 1,12 * see example 12 on p. 78 *; | [X]US2008188460 (CASARA PATRICK [FR], et al) [X] 1,10,12 * see preparation 17, steps I, J, K, L, M and N *; | [X]EP0463691 (MERCK SHARP & DOHME [GB]) [X] 1,10,12 * see examples 2 and 3 *; | [X]EP0206225 (MERCK PATENT GMBH [DE]) [X] 1,10,12 * see example 5, indole derivative and 5-hydroxyindole derivative *; | [A]WO2008007661 (TAKEDA PHARMACEUTICAL [JP], et al) [A] 1-32,34 * see the structure of the pyrazinobenzoxazines and pyrazinobenzodiazepines according to claim 1 and activity as 5-HT2-receptor agonists *; | [A]WO8807997 (UNIV MONASH [AU], et al) [A] 1-32,34 * see structure of the compounds of claim 1 and activity as 5-HT2-receptor anatgonists *; | [XI]WO2005047252 (WYETH CORP [US], et al) [X] 33 * see claims 10 to 13 directed to methods of treatment of disorders related to the 5-HT6 receptor * [I] 33; | [XI]WO2004074243 (WYETH CORP [US], et al) [X] 33 * see claims 10 to 14 directed to methods of treatment of disorders related to the 5-HT6 receptor * [I] 33; | [XI]WO2007032833 (WYETH CORP [US], et al) [X] 33 * see claims 10 to 14 directed to methods of treatment of disorders related to the 5-HT6 receptor * [I] 33 | [X] - RUSSELL, MICHAEL G. N. ET AL, "Benz[f]isoquinoline analogs as high-affinity .sigma. ligands", JOURNAL OF MEDICINAL CHEMISTRY , 35(11), 2025-33 CODEN: JMCMAR; ISSN: 0022-2623, (1992), XP009139166 [X] 1,10,12 * see compounds 44 and 45 in table IV on p. 2029 * DOI: http://dx.doi.org/10.1021/jm00089a012 | [X] - BHANDARI, K. ET AL, "Agents acting on the central nervous system. Part XXXIV. 1,2,3,4,4a,5,6,7-Octahydropyrazino[1,2-a]-1-benzazepines", INDIAN JOURNAL OF CHEMISTRY, SECTION B: ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY , 25B(12), 1231-3 CODEN: IJSBDB; ISSN: 0376-4699, (1986), XP009139173 [X] 1,10,12 * see compounds IIc, IId, IIf and IIg in chart I on p. 1232 * | [X] - MUELLER, WERNER ET AL, "Seven-membered heterocyclics. Part 29. Synthesis of 1,2-annelated 1,4-benzodiazepines and 4,1-benzoxazepines", HELVETICA CHIMICA ACTA , 65(7), 2118-32 CODEN: HCACAV; ISSN: 0018-019X, (1982), XP009139171 [X] 1,12,20 * see compound 65 in scheme 5 and reduction of compound 7 with LiAlH4 to give compound 10 on p. 2120, l. 11 to 12. * DOI: http://dx.doi.org/10.1002/hlca.19820650719 | [X] - SMITH, R. G. 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