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Extract from the Register of European Patents

EP About this file: EP2659890

EP2659890 - Methods and compositions for the treatment of fibrosis [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  07.03.2014
Database last updated on 25.09.2024
Most recent event   Tooltip07.03.2014Refusal of applicationpublished on 09.04.2014  [2014/15]
Applicant(s)For all designated states
Orphan Synergy Europe - Pharma
16 Rue du Général Leclerc
78000 Versailles / FR
[2013/45]
Representative(s)Tezier Herman, Béatrice, et al
Cabinet Becker & Associés
25, rue Louis le Grand
75002 Paris / FR
[2013/45]
Application number, filing date12305487.630.04.2012
[2013/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2659890
Date:06.11.2013
Language:EN
[2013/45]
Search report(s)(Supplementary) European search report - dispatched on:EP23.08.2012
ClassificationIPC:A61K31/47, A61P1/16
[2013/45]
CPC:
A61K31/4741 (EP,US); A61P1/00 (EP); A61P1/16 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/45]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:Verfahren und Zusammensetzungen zur Behandlung von Fibrose[2013/45]
English:Methods and compositions for the treatment of fibrosis[2013/45]
French:Procédé et compositions de traitement de la fibrose[2013/45]
Examination procedure20.11.2013Despatch of communication that the application is refused, reason: Examination on filing A.90(5) [2014/15]
30.11.2013Application refused, date of legal effect [2014/15]
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO8803023  (MITSUBISHI CHEM IND [JP]) [X] 1 * the whole document *;
 [Y]WO2009155611  (KINEMED INC [US], et al) [Y] 1-4 * claims 1,4,5 * * page 12, paragraph 0046 *;
 [XY]  - YUASA S ET AL, "SUPPRESSIVE EFFECTS OF TRITOQUALINE ON CELL GROWTH AND COLLAGEN SECRETION IN FIBROBLASTS", JAPANESE JOURNAL OF PHARMACOLOGY, (1986), vol. 40, no. 2, ISSN 0021-5198, pages 339 - 341, XP002681392 [X] 1,2 * page 339, abstract * [Y] 1-4

DOI:   http://dx.doi.org/10.1254/jjp.40.339
 [X]  - UMEZU K ET AL, "SUPPRESSIVE EFFECT OF TRITOQUALINE ON THE ACCELERATION OF FIBROSIS IN THE LIVER", FOLIA PHARMACOLOGICA JAPONICA, (1986), vol. 87, no. 3, ISSN 0015-5691, pages 291 - 300, XP002681393 [X] 1,2 * page 300, abstract *

DOI:   http://dx.doi.org/10.1254/fpj.87.291
 [X]  - YUASA S ET AL, "THERAPEUTIC EFFECT OF TRITOQUALINE ON CHRONIC LIVER INJURY MODEL IN RATS INDUCED BY CARBON TETRACHLORIDE", FOLIA PHARMACOLOGICA JAPONICA, (1985), vol. 85, no. 4, doi:10.1254/fpj.85.249, ISSN 0015-5691, pages 249 - 257, XP002681394 [X] 1,2 * page 257, abstract *
 [Y]  - ZIMMERMANN HENNING W ET AL, "Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis", PLOS ONE, (201106), vol. 6, no. 6, ISSN 1932-6203, XP002681395 [Y] 1-4 * page 1, abstract *

DOI:   http://dx.doi.org/10.1371/JOURNAL.PONE.0021381
by applicantWO2007117704
 WO2008100539
 US2010144718
    - E. PUCHELLE; S. DE BENTZMANN; C. HUBEAU; J. JACQUOT; D. GAILLARD, "Mechanisms involved in cystic fibrosis airway inflammation", PEDIATRIC PULMONOLOGY, (2001), vol. 32, no. 23, pages 143 - 145
    - ZIMMERMANN HW ET AL., "Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis", PLOS ONE, (2011), vol. 6, no. 6, doi:doi:10.1371/JOURNAL.PONE.0021381, page E21381, XP002681395

DOI:   http://dx.doi.org/10.1371/JOURNAL.PONE.0021381
    - E P DI SEBASTIANO, GUT, (2000), vol. 47, pages 423 - 428
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.